Notch signaling pathway Gene Set

Dataset PANTHER Pathways
Category structural or functional annotations
Type pathway
Description A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007219)
External Link http://www.pantherdb.org/pathway/pathDetail.do?clsAccession=P00045
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Genes

27 proteins participating in the Notch signaling pathway pathway from the PANTHER Pathways dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
CIR1 corepressor interacting with RBPJ, 1
DLK1 delta-like 1 homolog (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
JAG1 jagged 1
JAG2 jagged 2
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LNX2 ligand of numb-protein X 2
MAML1 mastermind-like 1 (Drosophila)
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
NCOR2 nuclear receptor corepressor 2
NCSTN nicastrin
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEURL2 neuralized E3 ubiquitin protein ligase 2
NEURL4 neuralized E3 ubiquitin protein ligase 4
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NUMB numb homolog (Drosophila)
POFUT1 protein O-fucosyltransferase 1
PSEN1 presenilin 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like