Neurological pain disorder_Dorsal Root Ganglia_GSE15041 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE15041
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Genes

600 genes differentially expressed during Neurological pain disorder_Dorsal Root Ganglia_GSE15041 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
DVL3 dishevelled segment polarity protein 3 3.97519
CHMP4B charged multivesicular body protein 4B 3.87466
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 3.78604
COG3 component of oligomeric golgi complex 3 3.61346
MAU2 MAU2 sister chromatid cohesion factor 3.45196
NMRAL1 NmrA-like family domain containing 1 3.32608
ZNF710 zinc finger protein 710 3.21724
SCUBE1 signal peptide, CUB domain, EGF-like 1 3.127
RASGEF1A RasGEF domain family, member 1A 3.09377
FOXD3 forkhead box D3 2.87775
MUTYH mutY homolog 2.73733
LENG8 leukocyte receptor cluster (LRC) member 8 2.68423
PRMT3 protein arginine methyltransferase 3 2.65188
CHRD chordin 2.64007
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2.63324
FAM171A1 family with sequence similarity 171, member A1 2.62129
NALCN sodium leak channel, non selective 2.60459
RABGAP1 RAB GTPase activating protein 1 2.59817
PAN3 PAN3 poly(A) specific ribonuclease subunit 2.59074
RTN1 reticulon 1 2.58401
XRN1 5'-3' exoribonuclease 1 2.54907
AFAP1 actin filament associated protein 1 2.47374
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 2.46777
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 2.4498
PNPLA3 patatin-like phospholipase domain containing 3 2.42863
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 2.40224
ENKD1 enkurin domain containing 1 2.39625
EPHB3 EPH receptor B3 2.38668
MYEF2 myelin expression factor 2 2.36323
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 2.35377
PIH1D2 PIH1 domain containing 2 2.33256
NEFH neurofilament, heavy polypeptide 2.328
MAPK4 mitogen-activated protein kinase 4 2.31653
MFAP1 microfibrillar-associated protein 1 2.25651
SIX3 SIX homeobox 3 2.24544
LIPT2 lipoyl(octanoyl) transferase 2 (putative) 2.22636
MAT2A methionine adenosyltransferase II, alpha 2.21132
CDK14 cyclin-dependent kinase 14 2.18311
PNPLA6 patatin-like phospholipase domain containing 6 2.18076
VASH2 vasohibin 2 2.1727
GARNL3 GTPase activating Rap/RanGAP domain-like 3 2.16785
UBE4A ubiquitination factor E4A 2.16674
MSMP microseminoprotein, prostate associated 2.15317
ADORA2A adenosine A2a receptor 2.14769
PTDSS1 phosphatidylserine synthase 1 2.14417
LALBA lactalbumin, alpha- 2.14382
PEX5 peroxisomal biogenesis factor 5 2.14355
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.14176
INTS4 integrator complex subunit 4 2.11607
N4BP2L1 NEDD4 binding protein 2-like 1 2.10143
PACS1 phosphofurin acidic cluster sorting protein 1 2.09849
NR2C1 nuclear receptor subfamily 2, group C, member 1 2.09657
FAM109B family with sequence similarity 109, member B 2.0914
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 2.0854
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 2.08059
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2.07968
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 2.06543
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 2.06214
RANGAP1 Ran GTPase activating protein 1 2.05422
FBXO34 F-box protein 34 2.02569
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 2.02523
GJB4 gap junction protein, beta 4, 30.3kDa 2.02397
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 2.02015
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.00694
SLC35B1 solute carrier family 35, member B1 1.99837
AHRR aryl-hydrocarbon receptor repressor 1.99547
SNAP91 synaptosomal-associated protein, 91kDa 1.98913
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 1.98784
HIP1R huntingtin interacting protein 1 related 1.97642
GDA guanine deaminase 1.9732
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 1.96724
BECN1 beclin 1, autophagy related 1.95977
CDC45 cell division cycle 45 1.95517
GJD2 gap junction protein, delta 2, 36kDa 1.94792
CHMP2B charged multivesicular body protein 2B 1.93073
RBM12 RNA binding motif protein 12 1.92767
RTN3 reticulon 3 1.9243
CDCA5 cell division cycle associated 5 1.9228
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.91201
SCAF8 SR-related CTD-associated factor 8 1.91146
DGKQ diacylglycerol kinase, theta 110kDa 1.90665
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 1.90611
CDC40 cell division cycle 40 1.90528
KIF12 kinesin family member 12 1.90347
EVL Enah/Vasp-like 1.89592
CLASP2 cytoplasmic linker associated protein 2 1.88813
MEF2B myocyte enhancer factor 2B 1.87386
GAS8 growth arrest-specific 8 1.87207
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 1.86196
KDM5B lysine (K)-specific demethylase 5B 1.86064
CLK4 CDC-like kinase 4 1.85565
UBA1 ubiquitin-like modifier activating enzyme 1 1.84792
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.84084
TMEM171 transmembrane protein 171 1.83749
FAM49A family with sequence similarity 49, member A 1.82266
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.82159
WDPCP WD repeat containing planar cell polarity effector 1.81213
WFDC2 WAP four-disulfide core domain 2 1.80344
SLC26A6 solute carrier family 26 (anion exchanger), member 6 1.80297
BMF Bcl2 modifying factor 1.80183
ITFG1 integrin alpha FG-GAP repeat containing 1 1.8005
KDM4B lysine (K)-specific demethylase 4B 1.76226
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 1.76196
PARP6 poly (ADP-ribose) polymerase family, member 6 1.76117
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.74469
OPA1 optic atrophy 1 (autosomal dominant) 1.74244
LRRC41 leucine rich repeat containing 41 1.74001
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 1.73814
EXOSC2 exosome component 2 1.73203
DOCK9 dedicator of cytokinesis 9 1.72547
LGMN legumain 1.72033
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.71962
HUS1 HUS1 checkpoint homolog (S. pombe) 1.71774
ATAD5 ATPase family, AAA domain containing 5 1.71611
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 1.70973
GARS glycyl-tRNA synthetase 1.70947
DTX4 deltex 4, E3 ubiquitin ligase 1.70457
FAM168A family with sequence similarity 168, member A 1.70238
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.6961
SDCBP syndecan binding protein (syntenin) 1.69576
STOX2 storkhead box 2 1.68663
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 1.68485
KCNK3 potassium channel, two pore domain subfamily K, member 3 1.68439
PDE8B phosphodiesterase 8B 1.6828
CHD2 chromodomain helicase DNA binding protein 2 1.67842
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 1.67136
UBE2G1 ubiquitin-conjugating enzyme E2G 1 1.66576
MED1 mediator complex subunit 1 1.65807
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 1.65695
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 1.65692
LENEP lens epithelial protein 1.65587
FGF4 fibroblast growth factor 4 1.65516
RGS8 regulator of G-protein signaling 8 1.6426
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.64043
RGS14 regulator of G-protein signaling 14 1.63854
ETV2 ets variant 2 1.63827
CLEC9A C-type lectin domain family 9, member A 1.63582
DGUOK deoxyguanosine kinase 1.63341
CPB1 carboxypeptidase B1 (tissue) 1.63208
TXLNA taxilin alpha 1.62386
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.62178
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 1.61972
WDR60 WD repeat domain 60 1.61667
GUCA2B guanylate cyclase activator 2B (uroguanylin) 1.59539
ANKRD12 ankyrin repeat domain 12 1.59466
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 1.58799
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.58456
CPNE7 copine VII 1.58096
YBX2 Y box binding protein 2 1.57783
TTYH3 tweety family member 3 1.57726
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 1.57601
SAMD4B sterile alpha motif domain containing 4B 1.57073
FOSL1 FOS-like antigen 1 1.56971
DCLRE1C DNA cross-link repair 1C 1.56955
GLOD5 glyoxalase domain containing 5 1.567
SPAG11B sperm associated antigen 11B 1.56212
ZNF780B zinc finger protein 780B 1.55122
CBX7 chromobox homolog 7 1.54721
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 1.54622
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.54209
PLEK2 pleckstrin 2 1.54042
RAB2B RAB2B, member RAS oncogene family 1.52991
CD86 CD86 molecule 1.52477
MED12 mediator complex subunit 12 1.52405
FGFR4 fibroblast growth factor receptor 4 1.52299
IGF2R insulin-like growth factor 2 receptor 1.51743
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 1.51679
TMEM41B transmembrane protein 41B 1.51398
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli) 1.50618
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.50323
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 1.49695
NFYA nuclear transcription factor Y, alpha 1.49597
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 1.49565
ATXN3 ataxin 3 1.49472
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 1.49275
TMEM63A transmembrane protein 63A 1.489
CLTC clathrin, heavy chain (Hc) 1.48634
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.48596
OLAH oleoyl-ACP hydrolase 1.47992
ZDHHC9 zinc finger, DHHC-type containing 9 1.4772
NF1 neurofibromin 1 1.47632
MED23 mediator complex subunit 23 1.47423
UNC13B unc-13 homolog B (C. elegans) 1.47393
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 1.47387
TRIM32 tripartite motif containing 32 1.4708
UBAP2 ubiquitin associated protein 2 1.46246
ZNF787 zinc finger protein 787 1.46142
FBXL6 F-box and leucine-rich repeat protein 6 1.46055
ELMO2 engulfment and cell motility 2 1.45808
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.45672
BMP3 bone morphogenetic protein 3 1.45521
FLT1 fms-related tyrosine kinase 1 1.45229
UPK1B uroplakin 1B 1.45195
ATN1 atrophin 1 1.45127
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.44805
BAIAP2 BAI1-associated protein 2 1.44465
DNALI1 dynein, axonemal, light intermediate chain 1 1.44217
CRYZL1 crystallin, zeta (quinone reductase)-like 1 1.4413
KIF2A kinesin heavy chain member 2A 1.4404
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 1.43604
ALB albumin 1.43005
WDR31 WD repeat domain 31 1.42893
CPEB3 cytoplasmic polyadenylation element binding protein 3 1.42458
TERF2IP telomeric repeat binding factor 2, interacting protein 1.42264
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 1.4218
GAB2 GRB2-associated binding protein 2 1.42111
ZDHHC23 zinc finger, DHHC-type containing 23 1.42021
ZNF362 zinc finger protein 362 1.41167
TRIM65 tripartite motif containing 65 1.41086
NTN1 netrin 1 1.40943
DDIT4 DNA-damage-inducible transcript 4 1.40741
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 1.40662
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 1.40596
ZDHHC13 zinc finger, DHHC-type containing 13 1.40374
DCAF4 DDB1 and CUL4 associated factor 4 1.40348
LIMS1 LIM and senescent cell antigen-like domains 1 1.40162
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 1.39546
USP10 ubiquitin specific peptidase 10 1.3952
TNR tenascin R 1.39233
FXYD4 FXYD domain containing ion transport regulator 4 1.39231
UBE3D ubiquitin protein ligase E3D 1.38913
TOP3B topoisomerase (DNA) III beta 1.38862
DIRC2 disrupted in renal carcinoma 2 1.38193
COX2 1.38048
NPW neuropeptide W 1.37888
DOC2B double C2-like domains, beta 1.37858
EPM2AIP1 EPM2A (laforin) interacting protein 1 1.37677
GIF gastric intrinsic factor (vitamin B synthesis) 1.37627
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 1.37414
NUMA1 nuclear mitotic apparatus protein 1 1.37264
KRT36 keratin 36, type I 1.36772
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.36641
CNKSR2 connector enhancer of kinase suppressor of Ras 2 1.35916
SCN7A sodium channel, voltage gated, type VII alpha subunit 1.35222
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.35107
CNKSR1 connector enhancer of kinase suppressor of Ras 1 1.3499
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase 1.34966
BPIFB2 BPI fold containing family B, member 2 1.34913
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 1.34734
TNRC6A trinucleotide repeat containing 6A 1.34681
ETF1 eukaryotic translation termination factor 1 1.34524
ATXN10 ataxin 10 1.34421
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.34139
RFWD3 ring finger and WD repeat domain 3 1.34061
RERG RAS-like, estrogen-regulated, growth inhibitor 1.33716
RBM44 RNA binding motif protein 44 1.33435
NME4 NME/NM23 nucleoside diphosphate kinase 4 1.3323
USP9X ubiquitin specific peptidase 9, X-linked 1.33109
KLHL35 kelch-like family member 35 1.33062
LAMA1 laminin, alpha 1 1.32713
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 1.32676
JAK1 Janus kinase 1 1.32663
HSF2BP heat shock transcription factor 2 binding protein 1.32658
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 1.32574
ADAM2 ADAM metallopeptidase domain 2 1.32538
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.3238
DMD dystrophin 1.32339
WAPAL wings apart-like homolog (Drosophila) 1.32237
UBQLN3 ubiquilin 3 1.32231
PROKR2 prokineticin receptor 2 1.32159
RB1 retinoblastoma 1 1.32109
RNASEK ribonuclease, RNase K 1.32074
PRRT4 proline-rich transmembrane protein 4 1.31982
SFXN1 sideroflexin 1 1.31902
CELA2A chymotrypsin-like elastase family, member 2A 1.31901
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 1.31895
GLT8D2 glycosyltransferase 8 domain containing 2 1.31571
FBXL8 F-box and leucine-rich repeat protein 8 1.31521
NEO1 neogenin 1 1.31494
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 1.31447
NANP N-acetylneuraminic acid phosphatase 1.31318
HDLBP high density lipoprotein binding protein 1.31272
GALP galanin-like peptide 1.31168
KLHL7 kelch-like family member 7 1.31144
GALC galactosylceramidase 1.31035
ALOX5 arachidonate 5-lipoxygenase 1.30727
SLC39A14 solute carrier family 39 (zinc transporter), member 14 1.30561
KIDINS220 kinase D-interacting substrate, 220kDa 1.30322
ACTG1 actin gamma 1 1.30191
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.30144
UNC5A unc-5 homolog A (C. elegans) 1.29849
FGF21 fibroblast growth factor 21 1.29593
CLCN5 chloride channel, voltage-sensitive 5 1.2923
NEK7 NIMA-related kinase 7 1.29076
ZFP57 ZFP57 zinc finger protein 1.2888
CLCN6 chloride channel, voltage-sensitive 6 1.28714
SHE Src homology 2 domain containing E 1.28699
YPEL4 yippee-like 4 (Drosophila) 1.28606
MEF2D myocyte enhancer factor 2D 1.28545
MEGF8 multiple EGF-like-domains 8 1.28544
ZFYVE1 zinc finger, FYVE domain containing 1 1.2788
RPUSD1 RNA pseudouridylate synthase domain containing 1 1.27643
RAB25 RAB25, member RAS oncogene family 1.27622
MON2 MON2 homolog (S. cerevisiae) 1.27601
CRYGA crystallin, gamma A 1.27478
CACUL1 CDK2-associated, cullin domain 1 1.27424
KRT14 keratin 14, type I 1.27316
LRRC57 leucine rich repeat containing 57 1.27106
MATR3 matrin 3 1.27045
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.26715

decreased expression

Symbol Name Standardized Value
MTO1 mitochondrial tRNA translation optimization 1 -3.86606
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -3.41102
IL17RC interleukin 17 receptor C -3.27583
PARD3 par-3 family cell polarity regulator -3.17565
PTGIS prostaglandin I2 (prostacyclin) synthase -3.13333
DUSP23 dual specificity phosphatase 23 -3.10438
ACOT1 acyl-CoA thioesterase 1 -2.95585
LRRK1 leucine-rich repeat kinase 1 -2.92701
CRABP1 cellular retinoic acid binding protein 1 -2.92167
DDB2 damage-specific DNA binding protein 2, 48kDa -2.85743
ZNF213 zinc finger protein 213 -2.84661
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -2.81886
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.80117
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -2.78668
NOS3 nitric oxide synthase 3 (endothelial cell) -2.75818
RANBP1 RAN binding protein 1 -2.73612
HOXC5 homeobox C5 -2.73105
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -2.72952
WNK4 WNK lysine deficient protein kinase 4 -2.7242
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -2.68989
DSN1 DSN1, MIS12 kinetochore complex component -2.62689
KIFC1 kinesin family member C1 -2.62376
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 -2.62313
CDC14B cell division cycle 14B -2.58697
PON1 paraoxonase 1 -2.57432
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.57359
KLF9 Kruppel-like factor 9 -2.54977
TNMD tenomodulin -2.54398
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -2.53881
KRT1 keratin 1, type II -2.53796
NAV2 neuron navigator 2 -2.47216
KIF11 kinesin family member 11 -2.47186
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -2.4395
ENGASE endo-beta-N-acetylglucosaminidase -2.41832
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -2.41444
KLC3 kinesin light chain 3 -2.40347
RPP14 ribonuclease P/MRP 14kDa subunit -2.39981
GPR27 G protein-coupled receptor 27 -2.38889
ZNF410 zinc finger protein 410 -2.34146
ARNT aryl hydrocarbon receptor nuclear translocator -2.32763
KLHL36 kelch-like family member 36 -2.32282
RPUSD4 RNA pseudouridylate synthase domain containing 4 -2.31869
MRPL12 mitochondrial ribosomal protein L12 -2.29515
NOVA2 neuro-oncological ventral antigen 2 -2.29325
TSC1 tuberous sclerosis 1 -2.28943
ZNF76 zinc finger protein 76 -2.28021
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -2.27821
PRSS36 protease, serine, 36 -2.27152
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -2.26366
MOK MOK protein kinase -2.26256
SP3 Sp3 transcription factor -2.23446
AMDHD2 amidohydrolase domain containing 2 -2.20388
SCNN1B sodium channel, non voltage gated 1 beta subunit -2.20336
OSBPL10 oxysterol binding protein-like 10 -2.20274
FOXM1 forkhead box M1 -2.19586
PTCH1 patched 1 -2.19432
NSD1 nuclear receptor binding SET domain protein 1 -2.1838
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -2.17192
CPA3 carboxypeptidase A3 (mast cell) -2.16902
FSCN3 fascin actin-bundling protein 3, testicular -2.15862
GSG1 germ cell associated 1 -2.15625
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 -2.15455
ACRBP acrosin binding protein -2.14732
BBS9 Bardet-Biedl syndrome 9 -2.12752
FANCF Fanconi anemia, complementation group F -2.12636
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -2.11685
NEU2 sialidase 2 (cytosolic sialidase) -2.10533
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 -2.10289
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase -2.0899
LARP7 La ribonucleoprotein domain family, member 7 -2.08524
RWDD1 RWD domain containing 1 -2.07207
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -2.05747
SFTPD surfactant protein D -2.05552
AGFG2 ArfGAP with FG repeats 2 -2.04824
MELK maternal embryonic leucine zipper kinase -2.04209
HJURP Holliday junction recognition protein -2.03378
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.01921
NUP188 nucleoporin 188kDa -2.01868
DCHS1 dachsous cadherin-related 1 -2.01147
SH3BP1 SH3-domain binding protein 1 -2.00081
GPR107 G protein-coupled receptor 107 -1.98923
PSCA prostate stem cell antigen -1.98465
FKBPL FK506 binding protein like -1.98122
NPHP4 nephronophthisis 4 -1.97913
KIF18B kinesin family member 18B -1.94441
OTUD3 OTU deubiquitinase 3 -1.94226
PPARA peroxisome proliferator-activated receptor alpha -1.94065
ACAD11 acyl-CoA dehydrogenase family, member 11 -1.93297
DENND2D DENN/MADD domain containing 2D -1.92937
VEGFC vascular endothelial growth factor C -1.92882
UPB1 ureidopropionase, beta -1.92475
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -1.924
TRMT61A tRNA methyltransferase 61A -1.91658
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -1.90491
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) -1.90129
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -1.90058
METTL7B methyltransferase like 7B -1.89943
GRID1 glutamate receptor, ionotropic, delta 1 -1.89508
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -1.89261
GOSR2 golgi SNAP receptor complex member 2 -1.8849
CALCRL calcitonin receptor-like -1.87988
ZSCAN10 zinc finger and SCAN domain containing 10 -1.87749
ANGPTL6 angiopoietin-like 6 -1.87749
NEUROD2 neuronal differentiation 2 -1.87749
ZNF593 zinc finger protein 593 -1.87373
PLG plasminogen -1.87347
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -1.87098
ZNF653 zinc finger protein 653 -1.87044
GRWD1 glutamate-rich WD repeat containing 1 -1.86111
CDC25A cell division cycle 25A -1.85582
UBIAD1 UbiA prenyltransferase domain containing 1 -1.8521
GPR62 G protein-coupled receptor 62 -1.85003
PRTG protogenin -1.84704
CD3G CD3g molecule, gamma (CD3-TCR complex) -1.83907
METTL18 methyltransferase like 18 -1.8373
TREX2 three prime repair exonuclease 2 -1.82991
ZUFSP zinc finger with UFM1-specific peptidase domain -1.82932
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -1.82141
PLK1 polo-like kinase 1 -1.82007
FAM64A family with sequence similarity 64, member A -1.81811
PDZD2 PDZ domain containing 2 -1.81315
SULF1 sulfatase 1 -1.81025
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -1.81009
EFNA2 ephrin-A2 -1.80135
RCOR2 REST corepressor 2 -1.80093
CAPN8 calpain 8 -1.79932
SCN2B sodium channel, voltage gated, type II beta subunit -1.79664
VARS2 valyl-tRNA synthetase 2, mitochondrial -1.79339
VSTM2B V-set and transmembrane domain containing 2B -1.79335
MCM3 minichromosome maintenance complex component 3 -1.79167
SPHK1 sphingosine kinase 1 -1.78976
ZNF474 zinc finger protein 474 -1.78485
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -1.7777
MED4 mediator complex subunit 4 -1.77718
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -1.77676
DLL3 delta-like 3 (Drosophila) -1.77643
F9 coagulation factor IX -1.77325
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 -1.76776
COL23A1 collagen, type XXIII, alpha 1 -1.7673
SUSD3 sushi domain containing 3 -1.7644
CASP9 caspase 9, apoptosis-related cysteine peptidase -1.76331
THOC3 THO complex 3 -1.76092
SESN3 sestrin 3 -1.75901
RFX1 regulatory factor X, 1 (influences HLA class II expression) -1.75746
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma -1.75407
FAM212A family with sequence similarity 212, member A -1.75368
DNAAF3 dynein, axonemal, assembly factor 3 -1.75348
COQ9 coenzyme Q9 -1.74942
ZNF827 zinc finger protein 827 -1.74827
PARK2 parkin RBR E3 ubiquitin protein ligase -1.74752
GSE1 Gse1 coiled-coil protein -1.74626
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -1.7413
CA7 carbonic anhydrase VII -1.7409
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa -1.73398
KLHDC8A kelch domain containing 8A -1.73354
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase -1.72525
ZNF575 zinc finger protein 575 -1.7247
NLE1 notchless homolog 1 (Drosophila) -1.7205
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -1.71989
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30 -1.7165
VSIG10L V-set and immunoglobulin domain containing 10 like -1.7108
SLC46A1 solute carrier family 46 (folate transporter), member 1 -1.70436
ATAD2 ATPase family, AAA domain containing 2 -1.70142
TSEN2 TSEN2 tRNA splicing endonuclease subunit -1.69609
VIPR2 vasoactive intestinal peptide receptor 2 -1.6913
TST thiosulfate sulfurtransferase (rhodanese) -1.69052
AGTR2 angiotensin II receptor, type 2 -1.68874
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 -1.68761
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -1.6783
MIER2 mesoderm induction early response 1, family member 2 -1.67691
TCF20 transcription factor 20 (AR1) -1.67106
ATP10A ATPase, class V, type 10A -1.6706
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -1.66678
PRICKLE3 prickle homolog 3 (Drosophila) -1.65995
BCL9 B-cell CLL/lymphoma 9 -1.65457
GANC glucosidase, alpha; neutral C -1.6543
TAS2R41 taste receptor, type 2, member 41 -1.65235
OXT oxytocin/neurophysin I prepropeptide -1.65235
ASRGL1 asparaginase like 1 -1.65079
POMC proopiomelanocortin -1.64957
ALS2CL ALS2 C-terminal like -1.64152
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -1.63898
GCKR glucokinase (hexokinase 4) regulator -1.63711
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -1.63423
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -1.63396
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -1.6318
NR2F6 nuclear receptor subfamily 2, group F, member 6 -1.63099
DESI2 desumoylating isopeptidase 2 -1.62004
ARMC2 armadillo repeat containing 2 -1.61959
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 -1.61643
TMEM108 transmembrane protein 108 -1.61612
RNF187 ring finger protein 187 -1.61143
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 -1.59975
WDR70 WD repeat domain 70 -1.59723
TFG TRK-fused gene -1.59653
GPR176 G protein-coupled receptor 176 -1.59623
CFDP1 craniofacial development protein 1 -1.58835
TMEM252 transmembrane protein 252 -1.5881
TSPAN5 tetraspanin 5 -1.58562
CLOCK clock circadian regulator -1.58382
EFNB3 ephrin-B3 -1.57884
ACOT8 acyl-CoA thioesterase 8 -1.57741
DRG2 developmentally regulated GTP binding protein 2 -1.57711
CNTLN centlein, centrosomal protein -1.57546
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -1.574
LRRC32 leucine rich repeat containing 32 -1.57338
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 -1.57029
EPPIN-WFDC6 EPPIN-WFDC6 readthrough -1.56604
PDGFA platelet-derived growth factor alpha polypeptide -1.56518
DMKN dermokine -1.55668
SIRT6 sirtuin 6 -1.55582
ALDOB aldolase B, fructose-bisphosphate -1.55381
KIF20A kinesin family member 20A -1.54975
IPO9 importin 9 -1.54935
ACTN4 actinin, alpha 4 -1.54832
FEV FEV (ETS oncogene family) -1.54533
MARCH9 membrane-associated ring finger (C3HC4) 9 -1.54455
OXA1L oxidase (cytochrome c) assembly 1-like -1.54116
FBXO31 F-box protein 31 -1.53859
SPINK5 serine peptidase inhibitor, Kazal type 5 -1.53723
POU3F2 POU class 3 homeobox 2 -1.53559
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -1.53498
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -1.53435
AADAT aminoadipate aminotransferase -1.5316
PODNL1 podocan-like 1 -1.52891
TMEM101 transmembrane protein 101 -1.52656
MAPK1 mitogen-activated protein kinase 1 -1.52594
SUMF2 sulfatase modifying factor 2 -1.52571
TKFC triokinase/FMN cyclase -1.52192
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -1.52053
WNT10A wingless-type MMTV integration site family, member 10A -1.51999
SCARF1 scavenger receptor class F, member 1 -1.51831
SOX30 SRY (sex determining region Y)-box 30 -1.51802
TARBP2 TAR (HIV-1) RNA binding protein 2 -1.51573
EXO1 exonuclease 1 -1.51539
POU2AF1 POU class 2 associating factor 1 -1.5137
GMPPB GDP-mannose pyrophosphorylase B -1.51105
TAS1R3 taste receptor, type 1, member 3 -1.5107
NFAM1 NFAT activating protein with ITAM motif 1 -1.50782
COL9A2 collagen, type IX, alpha 2 -1.50777
PRSS35 protease, serine, 35 -1.50682
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 -1.50674
PLAGL2 pleiomorphic adenoma gene-like 2 -1.50535
CDCA3 cell division cycle associated 3 -1.50323
FIBIN fin bud initiation factor homolog (zebrafish) -1.50141
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) -1.49784
SRF serum response factor (c-fos serum response element-binding transcription factor) -1.49567
HNF4A hepatocyte nuclear factor 4, alpha -1.49365
ALPK2 alpha-kinase 2 -1.49302
NR1H4 nuclear receptor subfamily 1, group H, member 4 -1.49142
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -1.49011
LRP2 low density lipoprotein receptor-related protein 2 -1.48675
RAD9B RAD9 homolog B (S. pombe) -1.48515
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -1.48337
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) -1.48189
COL4A4 collagen, type IV, alpha 4 -1.47913
NRTN neurturin -1.47909
NLGN2 neuroligin 2 -1.47871
MARCH10 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase -1.47782
COL6A3 collagen, type VI, alpha 3 -1.47242
PTH1R parathyroid hormone 1 receptor -1.47222
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -1.46946
LAD1 ladinin 1 -1.46632
RHBDL3 rhomboid, veinlet-like 3 (Drosophila) -1.46581
THUMPD2 THUMP domain containing 2 -1.46487
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -1.45758
FAM83D family with sequence similarity 83, member D -1.45733
GDF6 growth differentiation factor 6 -1.445
MSX2 msh homeobox 2 -1.44353
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) -1.44293
GALR3 galanin receptor 3 -1.44272
JDP2 Jun dimerization protein 2 -1.4401
BTBD17 BTB (POZ) domain containing 17 -1.43918
PARVG parvin, gamma -1.43753
STAR steroidogenic acute regulatory protein -1.43581
PLBD1 phospholipase B domain containing 1 -1.43536
PPP6C protein phosphatase 6, catalytic subunit -1.4346
FOXI2 forkhead box I2 -1.43304
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.43216
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 -1.42771
ADD2 adducin 2 (beta) -1.42657
ZBTB12 zinc finger and BTB domain containing 12 -1.42601
HAS2 hyaluronan synthase 2 -1.42297
DUT deoxyuridine triphosphatase -1.42259
WWC1 WW and C2 domain containing 1 -1.42237
AP4S1 adaptor-related protein complex 4, sigma 1 subunit -1.42113
PRPF19 pre-mRNA processing factor 19 -1.41958
POLM polymerase (DNA directed), mu -1.4182
MTF2 metal response element binding transcription factor 2 -1.41782
TRUB1 TruB pseudouridine (psi) synthase family member 1 -1.41675
RNASEH2B ribonuclease H2, subunit B -1.41527
PNKD paroxysmal nonkinesigenic dyskinesia -1.41464
SLC38A4 solute carrier family 38, member 4 -1.41435
XRCC6BP1 XRCC6 binding protein 1 -1.40724
RASL10A RAS-like, family 10, member A -1.40716
TMCO6 transmembrane and coiled-coil domains 6 -1.40582
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -1.40145
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.39873
PDE7B phosphodiesterase 7B -1.39345
OPRM1 opioid receptor, mu 1 -1.39338