Neovascularization, Pathologic Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

118 genes associated with the Neovascularization, Pathologic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGTR2 angiotensin II receptor, type 2
ANGPT2 angiopoietin 2
APAF1 apoptotic peptidase activating factor 1
AR androgen receptor
ARMS2 age-related maculopathy susceptibility 2
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BCL6 B-cell CLL/lymphoma 6
BIRC5 baculoviral IAP repeat containing 5
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CNR1 cannabinoid receptor 1 (brain)
COL18A1 collagen, type XVIII, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDIT4 DNA-damage-inducible transcript 4
EDN1 endothelin 1
EFNB2 ephrin-B2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPAS1 endothelial PAS domain protein 1
EPHB1 EPH receptor B1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGF4 fibroblast growth factor 4
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HP haptoglobin
HTRA1 HtrA serine peptidase 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDR kinase insert domain receptor
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LIPC lipase, hepatic
LTA lymphotoxin alpha
MICA MHC class I polypeptide-related sequence A
MIR126 microRNA 126
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTA1 metastasis associated 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NRP1 neuropilin 1
NRP2 neuropilin 2
ORM1 orosomucoid 1
PDCD1 programmed cell death 1
PDGFD platelet derived growth factor D
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAU plasminogen activator, urokinase
PLCG1 phospholipase C, gamma 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPRB protein tyrosine phosphatase, receptor type, B
PWAR1 Prader Willi/Angelman region RNA 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SOD2 superoxide dismutase 2, mitochondrial
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
ULK3 unc-51 like kinase 3
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
WT1 Wilms tumor 1