Nasopharyngeal Neoplasms Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

274 genes associated with the Nasopharyngeal Neoplasms phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ABT1 activator of basal transcription 1
ACE angiotensin I converting enzyme
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
ATXN1 ataxin 1
BCL2L12 BCL2-like 12 (proline rich)
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
BMP6 bone morphogenetic protein 6
BPIFA1 BPI fold containing family A, member 1
BPIFB1 BPI fold containing family B, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC170 coiled-coil domain containing 170
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCNE1 cyclin E1
CCNH cyclin H
CD209 CD209 molecule
CD44 CD44 molecule (Indian blood group)
CD83 CD83 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLPTM1L CLPTM1-like
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB5 cAMP responsive element binding protein 5
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCDC2 doublecortin domain containing 2
DCLRE1C DNA cross-link repair 1C
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEK DEK proto-oncogene
DLC1 DLC1 Rho GTPase activating protein
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DSP desmoplakin
DTNBP1 dystrobrevin binding protein 1
E2F3 E2F transcription factor 3
EDN1 endothelin 1
EDNRA endothelin receptor type A
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EME1 essential meiotic structure-specific endonuclease 1
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
F13A1 coagulation factor XIII, A1 polypeptide
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FEN1 flap structure-specific endonuclease 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GMPR guanosine monophosphate reductase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2H5 general transcription factor IIH, polypeptide 5
HCG9 HLA complex group 9 (non-protein coding)
HCP5 HLA complex P5 (non-protein coding)
HFE hemochromatosis
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HSPA1B heat shock 70kDa protein 1B
HUS1 HUS1 checkpoint homolog (S. pombe)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IL10 interleukin 10
IL12A interleukin 12A
IL16 interleukin 16
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23R interleukin 23 receptor
IL27 interleukin 27
IL6 interleukin 6
ITGA9 integrin, alpha 9
KIAA0319 KIAA0319
KIF13A kinesin family member 13A
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DL5B killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LAPTM4B lysosomal protein transmembrane 4 beta
LIG1 ligase I, DNA, ATP-dependent
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LTF lactotransferrin
LY86 lymphocyte antigen 86
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBD4 methyl-CpG binding domain protein 4
MBL2 mannose-binding lectin (protein C) 2, soluble
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MGMT O-6-methylguanine-DNA methyltransferase
MIR146A microRNA 146a
MIR196A2 microRNA 196a-2
MIR608 microRNA 608
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MT-TC tRNA
MT-TD tRNA
MT-TL2 tRNA
MT-TR tRNA
MT-TS1 tRNA
MT-TT tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUTYH mutY homolog
MYLIP myosin regulatory light chain interacting protein
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NAT6 N-acetyltransferase 6 (GCN5-related)
NBN nibrin
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOL7 nucleolar protein 7, 27kDa
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NUP153 nucleoporin 153kDa
OGG1 8-oxoguanine DNA glycosylase
OR2H1 olfactory receptor, family 2, subfamily H, member 1
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PIGR polymeric immunoglobulin receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNKP polynucleotide kinase 3'-phosphatase
POLB polymerase (DNA directed), beta
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAD51C RAD51 paralog C
RAD51D RAD51 paralog D
RAD52 RAD52 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RANBP9 RAN binding protein 9
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNR1 RNA, ribosomal cluster 1
RNR2 RNA, ribosomal cluster 2
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RREB1 ras responsive element binding protein 1
RXRA retinoid X receptor, alpha
SH2D3A SH2 domain containing 3A
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOD2 superoxide dismutase 2, mitochondrial
SPA17 sperm autoantigenic protein 17
SPP1 secreted phosphoprotein 1
SSR1 signal sequence receptor, alpha
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TDG thymine-DNA glycosylase
TDP2 tyrosyl-DNA phosphodiesterase 2
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB1 transforming growth factor, beta 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP73 tumor protein p73
TPMT thiopurine S-methyltransferase
TRIM38 tripartite motif containing 38
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UNG uracil-DNA glycosylase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNT3 wingless-type MMTV integration site family, member 3
XAB2 XPA binding protein 2
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB42 zinc finger and BTB domain containing 42