Muscular Dystrophy_Muscle - Striated (Skeletal) (MMHCC)_GSE2507 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2507
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Genes

600 genes differentially expressed during Muscular Dystrophy_Muscle - Striated (Skeletal) (MMHCC)_GSE2507 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
CCDC90B coiled-coil domain containing 90B 3.30968
REXO2 RNA exonuclease 2 3.22812
OTUD7B OTU deubiquitinase 7B 3.17851
RNGTT RNA guanylyltransferase and 5'-phosphatase 3.14611
ATG5 autophagy related 5 3.12427
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 3.07222
ACO2 aconitase 2, mitochondrial 2.92904
ISCA2 iron-sulfur cluster assembly 2 2.91114
ZNF598 zinc finger protein 598 2.84246
CNOT1 CCR4-NOT transcription complex, subunit 1 2.83221
HARS histidyl-tRNA synthetase 2.8314
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.78457
MRPL15 mitochondrial ribosomal protein L15 2.75271
OSBPL1A oxysterol binding protein-like 1A 2.72127
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.71718
CHMP3 charged multivesicular body protein 3 2.70467
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 2.65542
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 2.64351
USP48 ubiquitin specific peptidase 48 2.63955
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 2.638
NDEL1 nudE neurodevelopment protein 1-like 1 2.63572
RNF44 ring finger protein 44 2.62247
INPP5F inositol polyphosphate-5-phosphatase F 2.615
IRF5 interferon regulatory factor 5 2.61073
HOXB2 homeobox B2 2.59888
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2.59877
S100A14 S100 calcium binding protein A14 2.54882
MRFAP1 Morf4 family associated protein 1 2.54338
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.49311
SUN1 Sad1 and UNC84 domain containing 1 2.48314
FNTA farnesyltransferase, CAAX box, alpha 2.47696
CHD8 chromodomain helicase DNA binding protein 8 2.46371
FGF11 fibroblast growth factor 11 2.45557
DMP1 dentin matrix acidic phosphoprotein 1 2.43393
SRSF9 serine/arginine-rich splicing factor 9 2.4114
PDCL3 phosducin-like 3 2.3789
RPL13A ribosomal protein L13a 2.37058
SAMD4B sterile alpha motif domain containing 4B 2.36785
ESYT1 extended synaptotagmin-like protein 1 2.3586
EML5 echinoderm microtubule associated protein like 5 2.35431
RPS24 ribosomal protein S24 2.35294
SUMO3 small ubiquitin-like modifier 3 2.34784
UBA5 ubiquitin-like modifier activating enzyme 5 2.33886
SURF4 surfeit 4 2.33056
CDC42SE1 CDC42 small effector 1 2.3188
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 2.31744
ARPP19 cAMP-regulated phosphoprotein, 19kDa 2.30738
MRPL50 mitochondrial ribosomal protein L50 2.28901
IL27RA interleukin 27 receptor, alpha 2.28591
CRAMP1L Crm, cramped-like (Drosophila) 2.28157
SREBF1 sterol regulatory element binding transcription factor 1 2.26156
TBK1 TANK-binding kinase 1 2.20669
CACHD1 cache domain containing 1 2.20213
REG3G regenerating islet-derived 3 gamma 2.17657
TMED3 transmembrane emp24 protein transport domain containing 3 2.16582
PPA1 pyrophosphatase (inorganic) 1 2.1655
TNPO3 transportin 3 2.14151
EIF1B eukaryotic translation initiation factor 1B 2.14149
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 2.13711
COL9A2 collagen, type IX, alpha 2 2.13408
SSR1 signal sequence receptor, alpha 2.12987
RECQL RecQ helicase-like 2.12851
BASP1 brain abundant, membrane attached signal protein 1 2.10904
MSL1 male-specific lethal 1 homolog (Drosophila) 2.10526
C8ORF33 chromosome 8 open reading frame 33 2.09974
MEF2D myocyte enhancer factor 2D 2.09946
TP63 tumor protein p63 2.07805
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.06806
RPTN repetin 2.06772
ODC1 ornithine decarboxylase 1 2.05922
LIAS lipoic acid synthetase 2.05885
AKIRIN2 akirin 2 2.05193
SPRY4 sprouty homolog 4 (Drosophila) 2.04811
STX4 syntaxin 4 2.04357
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 2.03864
CCNF cyclin F 2.03713
TM2D1 TM2 domain containing 1 2.03315
LDLR low density lipoprotein receptor 2.02219
TMEM43 transmembrane protein 43 2.01302
SCARB2 scavenger receptor class B, member 2 2.01214
BTG1 B-cell translocation gene 1, anti-proliferative 2.00978
RAD21 RAD21 homolog (S. pombe) 2.00945
LUC7L LUC7-like (S. cerevisiae) 2.00045
SIAH2 siah E3 ubiquitin protein ligase 2 1.99044
SPOP speckle-type POZ protein 1.98501
ERO1LB ERO1-like beta (S. cerevisiae) 1.98431
CHMP5 charged multivesicular body protein 5 1.98353
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.97912
COMMD9 COMM domain containing 9 1.97683
SCAMP1 secretory carrier membrane protein 1 1.9751
EPX eosinophil peroxidase 1.97275
AHNAK AHNAK nucleoprotein 1.96737
C16ORF74 chromosome 16 open reading frame 74 1.96166
THUMPD1 THUMP domain containing 1 1.9613
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.95967
SLMO2 slowmo homolog 2 (Drosophila) 1.95819
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.95605
C9ORF3 chromosome 9 open reading frame 3 1.95527
RALBP1 ralA binding protein 1 1.94964
CAT catalase 1.9454
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 1.94459
NUDCD3 NudC domain containing 3 1.94038
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.93708
ZNF821 zinc finger protein 821 1.93244
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.92109
SMAD1 SMAD family member 1 1.92039
MRPL43 mitochondrial ribosomal protein L43 1.91901
GBAS glioblastoma amplified sequence 1.91897
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 1.91753
UBXN4 UBX domain protein 4 1.91136
SNX2 sorting nexin 2 1.90349
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 1.90277
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 1.9004
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.89739
ZMYND11 zinc finger, MYND-type containing 11 1.87399
CDK8 cyclin-dependent kinase 8 1.87098
GTPBP2 GTP binding protein 2 1.87035
KANSL2 KAT8 regulatory NSL complex subunit 2 1.86962
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.8669
GPX1 glutathione peroxidase 1 1.86281
HMP19 HMP19 protein 1.85937
BZW1 basic leucine zipper and W2 domains 1 1.85709
MYPOP Myb-related transcription factor, partner of profilin 1.85336
RNF141 ring finger protein 141 1.84485
DHRSX dehydrogenase/reductase (SDR family) X-linked 1.84248
TTL tubulin tyrosine ligase 1.84098
ATAD2B ATPase family, AAA domain containing 2B 1.83708
CYC1 cytochrome c-1 1.83574
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.83188
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 1.82745
SARS2 seryl-tRNA synthetase 2, mitochondrial 1.81579
DNM2 dynamin 2 1.81126
METTL7A methyltransferase like 7A 1.80941
GANAB glucosidase, alpha; neutral AB 1.80799
LDHAL6A lactate dehydrogenase A-like 6A 1.8077
RRP1B ribosomal RNA processing 1B 1.79432
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 1.79313
STX18 syntaxin 18 1.79274
GLCE glucuronic acid epimerase 1.78975
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.7896
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 1.78905
GPR12 G protein-coupled receptor 12 1.78312
NTSR1 neurotensin receptor 1 (high affinity) 1.77911
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.77631
ECE1 endothelin converting enzyme 1 1.77263
TNRC6A trinucleotide repeat containing 6A 1.77156
ZFP2 ZFP2 zinc finger protein 1.76748
TRAF3 TNF receptor-associated factor 3 1.76629
MTA2 metastasis associated 1 family, member 2 1.76599
SOAT2 sterol O-acyltransferase 2 1.75596
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.75136
SURF1 surfeit 1 1.74832
RAE1 ribonucleic acid export 1 1.74191
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.74069
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 1.74057
ADGRL1 adhesion G protein-coupled receptor L1 1.73596
APP amyloid beta (A4) precursor protein 1.73492
RABGGTB Rab geranylgeranyltransferase, beta subunit 1.73151
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 1.73069
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.73049
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.72957
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 1.71669
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.71498
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 1.71122
RB1 retinoblastoma 1 1.71035
GDI1 GDP dissociation inhibitor 1 1.70165
HMOX1 heme oxygenase 1 1.69826
PEX14 peroxisomal biogenesis factor 14 1.6953
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 1.69444
PABPN1 poly(A) binding protein, nuclear 1 1.69433
ALAD aminolevulinate dehydratase 1.68855
ERCC2 excision repair cross-complementation group 2 1.68306
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.68155
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.6792
PRSS8 protease, serine, 8 1.67574
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 1.67405
MRPL17 mitochondrial ribosomal protein L17 1.67207
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 1.6686
IQGAP1 IQ motif containing GTPase activating protein 1 1.6626
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.65292
PDLIM4 PDZ and LIM domain 4 1.6518
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.65169
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.65148
JMJD6 jumonji domain containing 6 1.63877
MAN1B1 mannosidase, alpha, class 1B, member 1 1.63505
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.63488
MAGED2 melanoma antigen family D2 1.63299
SF3B2 splicing factor 3b, subunit 2, 145kDa 1.63209
C9ORF72 chromosome 9 open reading frame 72 1.63064
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.62912
HIST2H2AB histone cluster 2, H2ab 1.62795
HOXA1 homeobox A1 1.61728
MCM3AP minichromosome maintenance complex component 3 associated protein 1.61612
HLA-A major histocompatibility complex, class I, A 1.61607
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.61539
GGNBP2 gametogenetin binding protein 2 1.6128
WIZ widely interspaced zinc finger motifs 1.6111
PML promyelocytic leukemia 1.61068
MOGS mannosyl-oligosaccharide glucosidase 1.60166
ITGA7 integrin, alpha 7 1.59809
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.59653
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.59552
SEC16A SEC16 homolog A (S. cerevisiae) 1.59125
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 1.59096
RPN1 ribophorin I 1.58653
PON2 paraoxonase 2 1.58599
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.5848
FAM8A1 family with sequence similarity 8, member A1 1.58137
DYNLL1 dynein, light chain, LC8-type 1 1.57764
MEF2B myocyte enhancer factor 2B 1.57756
SKAP2 src kinase associated phosphoprotein 2 1.57669
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 1.57626
PTGR1 prostaglandin reductase 1 1.57546
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.57
GLRX glutaredoxin (thioltransferase) 1.56981
RSU1 Ras suppressor protein 1 1.56859
CRYL1 crystallin, lambda 1 1.56087
TMEM62 transmembrane protein 62 1.55857
BTBD1 BTB (POZ) domain containing 1 1.55391
SERTAD1 SERTA domain containing 1 1.55369
GON4L gon-4-like (C. elegans) 1.55364
EPC1 enhancer of polycomb homolog 1 (Drosophila) 1.55346
CAPRIN2 caprin family member 2 1.55318
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.55227
ZDHHC7 zinc finger, DHHC-type containing 7 1.54654
ZNF771 zinc finger protein 771 1.54366
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 1.54288
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 1.53952
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 1.53716
SETD6 SET domain containing 6 1.53391
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.53381
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 1.52816
COL11A2 collagen, type XI, alpha 2 1.52757
DCK deoxycytidine kinase 1.52743
TRAM1 translocation associated membrane protein 1 1.52035
MAT2A methionine adenosyltransferase II, alpha 1.51716
DDR1 discoidin domain receptor tyrosine kinase 1 1.51672
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.51648
BCL2L2 BCL2-like 2 1.51171
PACRGL PARK2 co-regulated-like 1.51008
ANAPC4 anaphase promoting complex subunit 4 1.50921
MYOM2 myomesin 2 1.50731
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 1.50708
FAM96A family with sequence similarity 96, member A 1.50417
UBXN11 UBX domain protein 11 1.50149
CLTA clathrin, light chain A 1.50148
ALPPL2 alkaline phosphatase, placental-like 2 1.49662
ACTN2 actinin, alpha 2 1.49592
GPR27 G protein-coupled receptor 27 1.49271
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 1.49181
ELL elongation factor RNA polymerase II 1.49007
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.48931
PDIA4 protein disulfide isomerase family A, member 4 1.48865
PBX1 pre-B-cell leukemia homeobox 1 1.4834
CTSV cathepsin V 1.48297
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.48199
MFSD1 major facilitator superfamily domain containing 1 1.48133
CHD4 chromodomain helicase DNA binding protein 4 1.48004
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 1.47843
PTGFR prostaglandin F receptor (FP) 1.47304
USP8 ubiquitin specific peptidase 8 1.47093
HAUS8 HAUS augmin-like complex, subunit 8 1.47091
EVX1 even-skipped homeobox 1 1.46838
GBE1 glucan (1,4-alpha-), branching enzyme 1 1.46719
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.46322
CLEC16A C-type lectin domain family 16, member A 1.46262
ERH enhancer of rudimentary homolog (Drosophila) 1.46225
PARD3 par-3 family cell polarity regulator 1.45902
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.45525
QDPR quinoid dihydropteridine reductase 1.45468
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.45458
STK25 serine/threonine kinase 25 1.44767
RIC8A RIC8 guanine nucleotide exchange factor A 1.44688
MTCH1 mitochondrial carrier 1 1.44481
RCC2 regulator of chromosome condensation 2 1.44348
PSAT1 phosphoserine aminotransferase 1 1.44005
FAHD1 fumarylacetoacetate hydrolase domain containing 1 1.43904
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.43399
PLA2G10 phospholipase A2, group X 1.43209
IYD iodotyrosine deiodinase 1.43176
CXORF38 chromosome X open reading frame 38 1.42955
PRNP prion protein 1.42894
COX17 COX17 cytochrome c oxidase copper chaperone 1.42489
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 1.42195
USP3 ubiquitin specific peptidase 3 1.41883
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.4149
SLC39A9 solute carrier family 39, member 9 1.41417
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.40717
G6PC glucose-6-phosphatase, catalytic subunit 1.40574
SERGEF secretion regulating guanine nucleotide exchange factor 1.40457
IFNA4 interferon, alpha 4 1.40425
SMYD1 SET and MYND domain containing 1 1.40367
NFIB nuclear factor I/B 1.40289
RDX radixin 1.40153
CDK9 cyclin-dependent kinase 9 1.40129
TSPO translocator protein (18kDa) 1.40047
TMED4 transmembrane emp24 protein transport domain containing 4 1.399
OC90 otoconin 90 1.39776
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.39757
RPE ribulose-5-phosphate-3-epimerase 1.39585

decreased expression

Symbol Name Standardized Value
RBBP4 retinoblastoma binding protein 4 -3.55378
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -3.45825
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.34934
MRPS25 mitochondrial ribosomal protein S25 -3.31559
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -3.15147
STX12 syntaxin 12 -2.99593
KLHL9 kelch-like family member 9 -2.90034
MRPS7 mitochondrial ribosomal protein S7 -2.87213
TEX261 testis expressed 261 -2.86254
PTDSS1 phosphatidylserine synthase 1 -2.83701
KLHL7 kelch-like family member 7 -2.8336
PNKP polynucleotide kinase 3'-phosphatase -2.80749
RAB33B RAB33B, member RAS oncogene family -2.72082
MRPL48 mitochondrial ribosomal protein L48 -2.707
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.67791
NDE1 nudE neurodevelopment protein 1 -2.67462
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -2.6561
C11ORF58 chromosome 11 open reading frame 58 -2.6414
KDM3B lysine (K)-specific demethylase 3B -2.62901
PDCD2L programmed cell death 2-like -2.56144
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.55781
RPS11 ribosomal protein S11 -2.55664
COPS4 COP9 signalosome subunit 4 -2.55431
MBTPS1 membrane-bound transcription factor peptidase, site 1 -2.53978
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.53786
SKP1 S-phase kinase-associated protein 1 -2.52344
CSHL1 chorionic somatomammotropin hormone-like 1 -2.51676
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -2.50796
HFE hemochromatosis -2.50305
AURKAIP1 aurora kinase A interacting protein 1 -2.48912
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -2.48784
EXOSC5 exosome component 5 -2.48302
THAP4 THAP domain containing 4 -2.45817
SWI5 SWI5 recombination repair homolog (yeast) -2.45215
CD59 CD59 molecule, complement regulatory protein -2.44752
NGDN neuroguidin, EIF4E binding protein -2.42776
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -2.42427
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.4095
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.37707
PCBP2 poly(rC) binding protein 2 -2.35633
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.35021
PIAS1 protein inhibitor of activated STAT, 1 -2.34366
RAB7A RAB7A, member RAS oncogene family -2.3241
NCBP1 nuclear cap binding protein subunit 1, 80kDa -2.32308
C2ORF47 chromosome 2 open reading frame 47 -2.32133
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -2.31887
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -2.30381
AKR1E2 aldo-keto reductase family 1, member E2 -2.29361
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -2.2869
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.27308
MTMR10 myotubularin related protein 10 -2.26547
RPL6 ribosomal protein L6 -2.26431
IL6ST interleukin 6 signal transducer -2.24943
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -2.24897
CLTC clathrin, heavy chain (Hc) -2.22453
PEX11B peroxisomal biogenesis factor 11 beta -2.20873
MINOS1 mitochondrial inner membrane organizing system 1 -2.20837
CLCN7 chloride channel, voltage-sensitive 7 -2.2026
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -2.19689
MEMO1 mediator of cell motility 1 -2.19452
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -2.19168
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.18586
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.18179
SORBS3 sorbin and SH3 domain containing 3 -2.17961
SPRYD4 SPRY domain containing 4 -2.17853
TBRG1 transforming growth factor beta regulator 1 -2.17434
NEURL4 neuralized E3 ubiquitin protein ligase 4 -2.17411
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -2.16603
SMAP2 small ArfGAP2 -2.15951
GRB2 growth factor receptor-bound protein 2 -2.15815
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) -2.1543
REPS1 RALBP1 associated Eps domain containing 1 -2.13807
TP53 tumor protein p53 -2.12883
PCCB propionyl CoA carboxylase, beta polypeptide -2.12591
CLCN4 chloride channel, voltage-sensitive 4 -2.12131
LRRC59 leucine rich repeat containing 59 -2.11361
TTC27 tetratricopeptide repeat domain 27 -2.11219
ZBTB22 zinc finger and BTB domain containing 22 -2.10944
COPS6 COP9 signalosome subunit 6 -2.10497
SMAD2 SMAD family member 2 -2.10359
RAB35 RAB35, member RAS oncogene family -2.10134
SFXN2 sideroflexin 2 -2.09201
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -2.09113
GLUL glutamate-ammonia ligase -2.08775
YBX1 Y box binding protein 1 -2.07922
C11ORF31 chromosome 11 open reading frame 31 -2.07853
HAGH hydroxyacylglutathione hydrolase -2.07696
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -2.07447
ATG4B autophagy related 4B, cysteine peptidase -2.06779
CCT2 chaperonin containing TCP1, subunit 2 (beta) -2.06559
RABAC1 Rab acceptor 1 (prenylated) -2.06289
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -2.06032
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.05819
MRPL44 mitochondrial ribosomal protein L44 -2.05694
RPL7A ribosomal protein L7a -2.0532
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.05011
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.04811
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.03997
SH3PXD2A SH3 and PX domains 2A -2.02709
BRAP BRCA1 associated protein -2.02552
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.02542
CRAT carnitine O-acetyltransferase -2.01866
TPRG1L tumor protein p63 regulated 1-like -2.0112
FXN frataxin -1.96905
UBE2T ubiquitin-conjugating enzyme E2T -1.96326
CCNJ cyclin J -1.96166
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -1.95925
GTF2I general transcription factor IIi -1.95815
PHC1 polyhomeotic homolog 1 (Drosophila) -1.95566
SEC13 SEC13 homolog (S. cerevisiae) -1.95441
NFU1 NFU1 iron-sulfur cluster scaffold -1.95288
FAM114A2 family with sequence similarity 114, member A2 -1.95142
YY1 YY1 transcription factor -1.94582
PSTK phosphoseryl-tRNA kinase -1.94409
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -1.9409
RPP14 ribonuclease P/MRP 14kDa subunit -1.92495
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) -1.91536
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -1.90929
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -1.8995
FKBP9 FK506 binding protein 9, 63 kDa -1.89337
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -1.88911
IL15 interleukin 15 -1.88503
CXXC5 CXXC finger protein 5 -1.88093
TSPAN7 tetraspanin 7 -1.87756
RANGRF RAN guanine nucleotide release factor -1.87587
EDF1 endothelial differentiation-related factor 1 -1.87475
NF2 neurofibromin 2 (merlin) -1.87287
TESK1 testis-specific kinase 1 -1.87082
NUP62 nucleoporin 62kDa -1.85911
ADGRA3 adhesion G protein-coupled receptor A3 -1.85356
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.84743
NR1H3 nuclear receptor subfamily 1, group H, member 3 -1.84228
UROS uroporphyrinogen III synthase -1.84056
ATRAID all-trans retinoic acid-induced differentiation factor -1.83969
TFB2M transcription factor B2, mitochondrial -1.83892
CDK11A cyclin-dependent kinase 11A -1.837
CBR1 carbonyl reductase 1 -1.83598
RAB5C RAB5C, member RAS oncogene family -1.83402
H2AFX H2A histone family, member X -1.83362
ULK1 unc-51 like autophagy activating kinase 1 -1.83292
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -1.81925
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.81687
FAM136A family with sequence similarity 136, member A -1.80605
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -1.80474
SHMT1 serine hydroxymethyltransferase 1 (soluble) -1.80472
BIRC6 baculoviral IAP repeat containing 6 -1.80405
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -1.79866
EIF3C eukaryotic translation initiation factor 3, subunit C -1.79319
RAB6A RAB6A, member RAS oncogene family -1.79164
VWF von Willebrand factor -1.78969
ZNF706 zinc finger protein 706 -1.78784
UBC ubiquitin C -1.78548
DCTN6 dynactin 6 -1.78485
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -1.78281
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -1.77672
RPP21 ribonuclease P/MRP 21kDa subunit -1.77392
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -1.76726
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.76702
APLP2 amyloid beta (A4) precursor-like protein 2 -1.76162
DCTN3 dynactin 3 (p22) -1.75823
BMS1 BMS1 ribosome biogenesis factor -1.75744
ARL3 ADP-ribosylation factor-like 3 -1.7548
SCAMP3 secretory carrier membrane protein 3 -1.74624
MRPS21 mitochondrial ribosomal protein S21 -1.74235
NONO non-POU domain containing, octamer-binding -1.74166
SDCCAG3 serologically defined colon cancer antigen 3 -1.73773
MRPL28 mitochondrial ribosomal protein L28 -1.73338
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -1.73333
IVD isovaleryl-CoA dehydrogenase -1.73278
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.73044
ZC3H14 zinc finger CCCH-type containing 14 -1.72835
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -1.72634
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -1.72429
ICT1 immature colon carcinoma transcript 1 -1.72112
FCF1 FCF1 rRNA-processing protein -1.72028
MRPL52 mitochondrial ribosomal protein L52 -1.71862
COQ3 coenzyme Q3 methyltransferase -1.7173
GOLGA5 golgin A5 -1.70697
MED23 mediator complex subunit 23 -1.70454
SEP15 15 kDa selenoprotein -1.70445
LBR lamin B receptor -1.69995
NIP7 NIP7, nucleolar pre-rRNA processing protein -1.69853
HIGD1A HIG1 hypoxia inducible domain family, member 1A -1.69742
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -1.69427
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -1.69025
FOXP2 forkhead box P2 -1.68776
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -1.68753
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -1.68018
TUBA4A tubulin, alpha 4a -1.67917
NTAN1 N-terminal asparagine amidase -1.67161
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta -1.6716
USP25 ubiquitin specific peptidase 25 -1.66894
MRPL16 mitochondrial ribosomal protein L16 -1.66874
YIPF1 Yip1 domain family, member 1 -1.66853
ANG angiogenin, ribonuclease, RNase A family, 5 -1.66543
HINT1 histidine triad nucleotide binding protein 1 -1.66498
PHB prohibitin -1.65861
GATA4 GATA binding protein 4 -1.65408
RPUSD4 RNA pseudouridylate synthase domain containing 4 -1.65365
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -1.65281
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -1.6518
RPS25 ribosomal protein S25 -1.64178
EMC10 ER membrane protein complex subunit 10 -1.64017
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -1.63848
IGBP1 immunoglobulin (CD79A) binding protein 1 -1.63595
RET ret proto-oncogene -1.63444
RNPEP arginyl aminopeptidase (aminopeptidase B) -1.63259
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -1.63253
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -1.63203
NIT2 nitrilase family, member 2 -1.62391
RPL10A ribosomal protein L10a -1.6218
FAM50A family with sequence similarity 50, member A -1.62075
MRPL13 mitochondrial ribosomal protein L13 -1.61776
NRD1 nardilysin (N-arginine dibasic convertase) -1.6153
ACTL6A actin-like 6A -1.61439
ZNFX1 zinc finger, NFX1-type containing 1 -1.61436
SNX6 sorting nexin 6 -1.61188
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -1.61112
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -1.60761
UBE2O ubiquitin-conjugating enzyme E2O -1.60383
ACYP2 acylphosphatase 2, muscle type -1.60344
MAK16 MAK16 homolog (S. cerevisiae) -1.60212
SLC25A44 solute carrier family 25, member 44 -1.60145
CECR6 cat eye syndrome chromosome region, candidate 6 -1.59853
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -1.59754
RPS7 ribosomal protein S7 -1.59407
C20ORF24 chromosome 20 open reading frame 24 -1.59355
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -1.59117
USP6NL USP6 N-terminal like -1.5896
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -1.58498
TBC1D10A TBC1 domain family, member 10A -1.58231
SNX14 sorting nexin 14 -1.57984
SEC61B Sec61 beta subunit -1.57952
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 -1.57888
REEP6 receptor accessory protein 6 -1.57541
H1F0 H1 histone family, member 0 -1.57522
CTSC cathepsin C -1.57177
PLRG1 pleiotropic regulator 1 -1.57047
LIG3 ligase III, DNA, ATP-dependent -1.56989
FICD FIC domain containing -1.56521
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -1.56239
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -1.55504
MRPL55 mitochondrial ribosomal protein L55 -1.55314
IPO11 importin 11 -1.55186
RCL1 RNA terminal phosphate cyclase-like 1 -1.55143
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -1.54246
RPS4Y1 ribosomal protein S4, Y-linked 1 -1.54189
MARCH5 membrane-associated ring finger (C3HC4) 5 -1.5393
ABHD16A abhydrolase domain containing 16A -1.53787
COA3 cytochrome c oxidase assembly factor 3 -1.53726
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -1.53561
SWAP70 SWAP switching B-cell complex 70kDa subunit -1.53347
PTTG1 pituitary tumor-transforming 1 -1.53204
ZNF277 zinc finger protein 277 -1.52842
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -1.52818
FAF1 Fas (TNFRSF6) associated factor 1 -1.52494
GTPBP1 GTP binding protein 1 -1.52469
CCDC12 coiled-coil domain containing 12 -1.52393
GBA glucosidase, beta, acid -1.51798
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -1.51796
SNAP47 synaptosomal-associated protein, 47kDa -1.51742
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -1.51738
TOMM34 translocase of outer mitochondrial membrane 34 -1.51313
ZNF106 zinc finger protein 106 -1.51056
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -1.50361
LTA4H leukotriene A4 hydrolase -1.50348
APC2 adenomatosis polyposis coli 2 -1.50071
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -1.49242
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 -1.48951
ITLN1 intelectin 1 (galactofuranose binding) -1.48878
INTS3 integrator complex subunit 3 -1.48518
RNF166 ring finger protein 166 -1.48429
MGST1 microsomal glutathione S-transferase 1 -1.48395
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -1.47937
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -1.47624
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -1.47608
FDPS farnesyl diphosphate synthase -1.47477
STRAP serine/threonine kinase receptor associated protein -1.47464
RPL7 ribosomal protein L7 -1.47272
VDAC2 voltage-dependent anion channel 2 -1.47192
ANKRD40 ankyrin repeat domain 40 -1.47132
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -1.46347
EFTUD2 elongation factor Tu GTP binding domain containing 2 -1.46276
PXN paxillin -1.46174
SDHAF1 succinate dehydrogenase complex assembly factor 1 -1.45411
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -1.45092
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -1.44817
AK3 adenylate kinase 3 -1.44622
NPEPPS aminopeptidase puromycin sensitive -1.4396
DCAF11 DDB1 and CUL4 associated factor 11 -1.4382
SEC24B SEC24 family member B -1.43777
SNAPIN SNAP-associated protein -1.43159
SPATA6 spermatogenesis associated 6 -1.42906
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -1.42733
ANXA6 annexin A6 -1.42574
TMEM131 transmembrane protein 131 -1.42483
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -1.42284
GOLGA3 golgin A3 -1.42255
OLFM2 olfactomedin 2 -1.42091
GNPAT glyceronephosphate O-acyltransferase -1.4174