Muscle Weakness Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Reduced strength of muscles. (Human Phenotype Ontology, HP_0001324)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D018908
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Genes

1076 genes/proteins associated with the disease Muscle Weakness from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AMPD1 adenosine monophosphate deaminase 1 2.88009
TTN titin 2.88009
MYOT myotilin 2.88009
PMP22 peripheral myelin protein 22 2.88009
GYG1 glycogenin 1 2.88009
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.88009
CSF3 colony stimulating factor 3 (granulocyte) 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.51631
TNF tumor necrosis factor 2.50334
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.49416
IL6 interleukin 6 2.44954
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.44315
BCL2 B-cell CLL/lymphoma 2 2.44293
CAT catalase 2.42488
JUN jun proto-oncogene 2.42215
BAX BCL2-associated X protein 2.42057
FAS Fas cell surface death receptor 2.40959
FOS FBJ murine osteosarcoma viral oncogene homolog 2.39144
CCL2 chemokine (C-C motif) ligand 2 2.38779
IL1B interleukin 1, beta 2.36771
IFNG interferon, gamma 2.35368
TP53 tumor protein p53 2.35368
CXCL8 chemokine (C-X-C motif) ligand 8 2.31279
SOD2 superoxide dismutase 2, mitochondrial 2.29128
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.2838
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.26985
GSTP1 glutathione S-transferase pi 1 2.26318
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.2572
MAPK3 mitogen-activated protein kinase 3 2.25616
VEGFA vascular endothelial growth factor A 2.24928
MAPK1 mitogen-activated protein kinase 1 2.24831
NR1I2 nuclear receptor subfamily 1, group I, member 2 2.23122
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.22887
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.22668
HMOX1 heme oxygenase 1 2.22161
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.2105
EGR1 early growth response 1 2.19456
NOS2 nitric oxide synthase 2, inducible 2.18116
ICAM1 intercellular adhesion molecule 1 2.16277
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.15853
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.15105
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.12495
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.11899
TGFB1 transforming growth factor, beta 1 2.11787
POMC proopiomelanocortin 2.11717
VCAM1 vascular cell adhesion molecule 1 2.10519
GSK3B glycogen synthase kinase 3 beta 2.10508
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.09557
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 2.08645
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.08056
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.07624
IL4 interleukin 4 2.07467
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.06997
BCL2L1 BCL2-like 1 2.06635
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.061
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.06051
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.05395
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.05332
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.04254
GADD45A growth arrest and DNA-damage-inducible, alpha 2.03637
IL1A interleukin 1, alpha 2.02839
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 2.02712
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.02445
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 2.01554
ALB albumin 2.01376
MPO myeloperoxidase 2.012
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.01146
APP amyloid beta (A4) precursor protein 1.99625
PARP1 poly (ADP-ribose) polymerase 1 1.98799
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.98496
SOD1 superoxide dismutase 1, soluble 1.97552
EDN1 endothelin 1 1.96979
MAPK8 mitogen-activated protein kinase 8 1.9667
FASLG Fas ligand (TNF superfamily, member 6) 1.95676
CCND1 cyclin D1 1.95435
DDIT3 DNA-damage-inducible transcript 3 1.95315
ATF3 activating transcription factor 3 1.94516
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.94233
EGFR epidermal growth factor receptor 1.93597
BDNF brain-derived neurotrophic factor 1.93152
THBS1 thrombospondin 1 1.92769
IL2 interleukin 2 1.92422
POR P450 (cytochrome) oxidoreductase 1.92297
APOB apolipoprotein B 1.91911
IL10 interleukin 10 1.91814
PLAT plasminogen activator, tissue 1.91034
IGF1 insulin-like growth factor 1 (somatomedin C) 1.90853
CTSL cathepsin L 1.90325
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.8996
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.89617
MCL1 myeloid cell leukemia 1 1.89216
CXCL10 chemokine (C-X-C motif) ligand 10 1.86062
NPPB natriuretic peptide B 1.84835
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.84376
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.84323
PRL prolactin 1.84251
GSTM1 glutathione S-transferase mu 1 1.83984
CYCS cytochrome c, somatic 1.83877
TIMP1 TIMP metallopeptidase inhibitor 1 1.83467
GFAP glial fibrillary acidic protein 1.83361
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.8329
F2 coagulation factor II (thrombin) 1.83007
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.82901
REN renin 1.82656
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.82011
MMP9 matrix metallopeptidase 9 1.81976
S100A9 S100 calcium binding protein A9 1.81684
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.81629
DUSP1 dual specificity phosphatase 1 1.81502
GSR glutathione reductase 1.80756
PPARG peroxisome proliferator-activated receptor gamma 1.80341
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.79637
NEFH neurofilament, heavy polypeptide 1.79408
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.79273
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.78854
PPARA peroxisome proliferator-activated receptor alpha 1.78188
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.78168
APOE apolipoprotein E 1.77394
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.76966
PCNA proliferating cell nuclear antigen 1.76946
CFLAR CASP8 and FADD-like apoptosis regulator 1.76752
CLU clusterin 1.76752
TAT tyrosine aminotransferase 1.76636
FGF2 fibroblast growth factor 2 (basic) 1.76578
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.75321
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.74782
ODC1 ornithine decarboxylase 1 1.74681
NQO1 NAD(P)H dehydrogenase, quinone 1 1.74641
STAR steroidogenic acute regulatory protein 1.74541
GPX1 glutathione peroxidase 1 1.73414
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.73129
CCL5 chemokine (C-C motif) ligand 5 1.73008
COL1A1 collagen, type I, alpha 1 1.73008
SRGN serglycin 1.73008
BTG2 BTG family, member 2 1.7226
MAPT microtubule-associated protein tau 1.7226
NFE2L2 nuclear factor, erythroid 2-like 2 1.72219
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.72014
HSPA8 heat shock 70kDa protein 8 1.71565
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.70719
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.70636
IL5 interleukin 5 1.70553
NOS3 nitric oxide synthase 3 (endothelial cell) 1.70244
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.70119
GCLC glutamate-cysteine ligase, catalytic subunit 1.70056
MMP2 matrix metallopeptidase 2 1.70035
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.69721
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.69513
NPPA natriuretic peptide A 1.69405
VIM vimentin 1.69405
CP ceruloplasmin (ferroxidase) 1.69103
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.68062
CCND3 cyclin D3 1.68062
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.67654
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.67654
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.67398
TAGLN transgelin 1.67376
NPY neuropeptide Y 1.67159
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.66986
CCNB1 cyclin B1 1.66382
INHBE inhibin, beta E 1.66081
HSPA1A heat shock 70kDa protein 1A 1.65908
EGR2 early growth response 2 1.65797
NUPR1 nuclear protein, transcriptional regulator, 1 1.65665
SGK1 serum/glucocorticoid regulated kinase 1 1.65665
LHB luteinizing hormone beta polypeptide 1.65136
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.64797
CES2 carboxylesterase 2 1.64775
TRIB3 tribbles pseudokinase 3 1.64595
ACO2 aconitase 2, mitochondrial 1.64146
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.63743
ECI1 enoyl-CoA delta isomerase 1 1.63653
CDK5 cyclin-dependent kinase 5 1.63361
C3 complement component 3 1.63339
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.6325
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.63227
CD44 CD44 molecule (Indian blood group) 1.62938
S100A8 S100 calcium binding protein A8 1.6278
ACHE acetylcholinesterase (Yt blood group) 1.62423
BIRC5 baculoviral IAP repeat containing 5 1.62357
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.62357
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.6229
BBC3 BCL2 binding component 3 1.6206
FGB fibrinogen beta chain 1.62036
CDK2 cyclin-dependent kinase 2 1.61851
CYBA cytochrome b-245, alpha polypeptide 1.61805
KLF4 Kruppel-like factor 4 (gut) 1.61736
FN1 fibronectin 1 1.61271
MAPK14 mitogen-activated protein kinase 14 1.61131
NRP1 neuropilin 1 1.60267
RRM2 ribonucleotide reductase M2 1.5992
ANGPTL4 angiopoietin-like 4 1.5992
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.59685
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.58818
CDK4 cyclin-dependent kinase 4 1.58327
TH tyrosine hydroxylase 1.5816
FASN fatty acid synthase 1.5816
RB1 retinoblastoma 1 1.58018
LPL lipoprotein lipase 1.58018
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.58018
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.57994
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.57877
BMP4 bone morphogenetic protein 4 1.57498
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.5721
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.5678
MMP13 matrix metallopeptidase 13 1.5678
CRP C-reactive protein, pentraxin-related 1.56239
G6PC glucose-6-phosphatase, catalytic subunit 1.56141
E2F1 E2F transcription factor 1 1.56117
GSTO1 glutathione S-transferase omega 1 1.56092
ECH1 enoyl CoA hydratase 1, peroxisomal 1.55747
CTSB cathepsin B 1.55698
IGFBP1 insulin-like growth factor binding protein 1 1.55698
NFE2L1 nuclear factor, erythroid 2-like 1 1.55574
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.55574
CCL3 chemokine (C-C motif) ligand 3 1.55525
RELN reelin 1.55378
TNNI3 troponin I type 3 (cardiac) 1.55378
CTGF connective tissue growth factor 1.55353
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.55108
JAK1 Janus kinase 1 1.55108
APOA1 apolipoprotein A-I 1.54475
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.54475
SCARB1 scavenger receptor class B, member 1 1.54427
CD14 CD14 molecule 1.54427
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.54354
G6PD glucose-6-phosphate dehydrogenase 1.54306
ATF5 activating transcription factor 5 1.54159
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.53892
DHCR24 24-dehydrocholesterol reductase 1.53844
CTSD cathepsin D 1.53431
XDH xanthine dehydrogenase 1.53283
ADRB1 adrenoceptor beta 1 1.52642
SLCO1B1 solute carrier organic anion transporter family, member 1B1 1.52566
SERINC3 serine incorporator 3 1.52313
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.52262
GSN gelsolin 1.52036
IL2RA interleukin 2 receptor, alpha 1.51734
FABP1 fatty acid binding protein 1, liver 1.51657
ALDOA aldolase A, fructose-bisphosphate 1.5143
CREB1 cAMP responsive element binding protein 1 1.5103
CRH corticotropin releasing hormone 1.50953
FGA fibrinogen alpha chain 1.50549
KRT8 keratin 8, type II 1.50498
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.50273
PDLIM7 PDZ and LIM domain 7 (enigma) 1.50273
IGFBP3 insulin-like growth factor binding protein 3 1.49915
TAC1 tachykinin, precursor 1 1.4966
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.4966
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.49584
EDNRB endothelin receptor type B 1.49356
GPX3 glutathione peroxidase 3 1.49356
FMO1 flavin containing monooxygenase 1 1.49148
HSPA1B heat shock 70kDa protein 1B 1.49122
LDLR low density lipoprotein receptor 1.48967
BAK1 BCL2-antagonist/killer 1 1.48916
CYP3A cytochrome P450, family 3, subfamily A 1.48479
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.48325
ACTA2 actin, alpha 2, smooth muscle, aorta 1.48093
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.47582
C10ORF10 chromosome 10 open reading frame 10 1.47426
NGF nerve growth factor (beta polypeptide) 1.47322
INA internexin neuronal intermediate filament protein, alpha 1.47296
XBP1 X-box binding protein 1 1.47167
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.47167
FOSL2 FOS-like antigen 2 1.47115
PLG plasminogen 1.47115
CCNA2 cyclin A2 1.47038
CALB1 calbindin 1, 28kDa 1.46986
ERBB2 erb-b2 receptor tyrosine kinase 2 1.46935
LOX lysyl oxidase 1.46701
MGMT O-6-methylguanine-DNA methyltransferase 1.46304
CREBBP CREB binding protein 1.46198
ATF4 activating transcription factor 4 1.46093
PPARD peroxisome proliferator-activated receptor delta 1.45936
IL18 interleukin 18 1.4575
TOP2A topoisomerase (DNA) II alpha 170kDa 1.4575
PON1 paraoxonase 1 1.4575
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.4567
ATM ATM serine/threonine kinase 1.4567
CD151 CD151 molecule (Raph blood group) 1.45431
GAMT guanidinoacetate N-methyltransferase 1.4522
TLR4 toll-like receptor 4 1.4522
CALR calreticulin 1.44899
GJA1 gap junction protein, alpha 1, 43kDa 1.44872
IGF1R insulin-like growth factor 1 receptor 1.44845
TIMP2 TIMP metallopeptidase inhibitor 2 1.44626
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.44139
MAOB monoamine oxidase B 1.43864
CA2 carbonic anhydrase II 1.43864
STMN1 stathmin 1 1.43864
ADCY7 adenylate cyclase 7 1.43646
GBP1 guanylate binding protein 1, interferon-inducible 1.43646
ACACB acetyl-CoA carboxylase beta 1.4351
EPO erythropoietin 1.43374
RHOA ras homolog family member A 1.4313
EPHX2 epoxide hydrolase 2, cytoplasmic 1.4313
BUB3 BUB3 mitotic checkpoint protein 1.43048
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.42696
INS insulin 1.42616
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.42508
FADS2 fatty acid desaturase 2 1.42266
S100A4 S100 calcium binding protein A4 1.42266
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.42156
CDK1 cyclin-dependent kinase 1 1.42074
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.41965
COL6A2 collagen, type VI, alpha 2 1.41965
PDE4B phosphodiesterase 4B, cAMP-specific 1.41965
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.41884
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.41694
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.41667
TYMS thymidylate synthetase 1.41613
FOXO1 forkhead box O1 1.41396
CKM creatine kinase, muscle 1.41119
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.4076
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.40732
APOC3 apolipoprotein C-III 1.40732
HSPB1 heat shock 27kDa protein 1 1.40705
NOX4 NADPH oxidase 4 1.40513
INHA inhibin, alpha 1.40373
SUCLG1 succinate-CoA ligase, alpha subunit 1.40373
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.40345
BIRC3 baculoviral IAP repeat containing 3 1.40092
TYMP thymidine phosphorylase 1.39952
KLF2 Kruppel-like factor 2 1.39952
LEP leptin 1.39869
TRIM2 tripartite motif containing 2 1.39841
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.39841
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.39591
CHEK2 checkpoint kinase 2 1.39591
NBN nibrin 1.39338
HSPE1 heat shock 10kDa protein 1 1.39338
RGS4 regulator of G-protein signaling 4 1.39226
SPP1 secreted phosphoprotein 1 1.39198
DRD1 dopamine receptor D1 1.39142
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.39142
BID BH3 interacting domain death agonist 1.38974
MAOA monoamine oxidase A 1.38918
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.38918
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.38835
GSTT1 glutathione S-transferase theta 1 1.3878
TUBB tubulin, beta class I 1.38498
SDC4 syndecan 4 1.38498
TUBB3 tubulin, beta 3 class III 1.38498
SELE selectin E 1.38469
STIP1 stress-induced phosphoprotein 1 1.38128
ANXA4 annexin A4 1.38128
GNAS GNAS complex locus 1.37958
MAP2 microtubule-associated protein 2 1.37761
OAT ornithine aminotransferase 1.37676
F3 coagulation factor III (thromboplastin, tissue factor) 1.3759
MUCL1 mucin-like 1 1.37532
FADS1 fatty acid desaturase 1 1.37418
GCLM glutamate-cysteine ligase, modifier subunit 1.37303
DRD2 dopamine receptor D2 1.37132
JUNB jun B proto-oncogene 1.3699
C1S complement component 1, s subcomponent 1.36706
H2AFX H2A histone family, member X 1.36447
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.36447
GADD45G growth arrest and DNA-damage-inducible, gamma 1.36332
KLF6 Kruppel-like factor 6 1.36332
IL12B interleukin 12B 1.36247
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.36019
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.36019
EZR ezrin 1.35705
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.35676
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.35618
TF transferrin 1.35444
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.35184
PKLR pyruvate kinase, liver and RBC 1.34694
GRN granulin 1.34694
GJB1 gap junction protein, beta 1, 32kDa 1.34694
MMP3 matrix metallopeptidase 3 1.34635
UBE2I ubiquitin-conjugating enzyme E2I 1.34606
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.34606
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.34518
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.34372
BAG3 BCL2-associated athanogene 3 1.34024
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.34024
RGS2 regulator of G-protein signaling 2 1.33995
LDHA lactate dehydrogenase A 1.33995
COL1A2 collagen, type I, alpha 2 1.3382
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.3382
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.3382
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.33761
DCN decorin 1.33701
GEM GTP binding protein overexpressed in skeletal muscle 1.33701
PSAP prosaposin 1.33701
ACADVL acyl-CoA dehydrogenase, very long chain 1.33701
ACADL acyl-CoA dehydrogenase, long chain 1.33701
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.33701
DPP4 dipeptidyl-peptidase 4 1.33701
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.33405
IL23A interleukin 23, alpha subunit p19 1.33287
CA3 carbonic anhydrase III 1.33287
OSBPL10 oxysterol binding protein-like 10 1.33228
MEP1B meprin A, beta 1.33228
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.33081
AXL AXL receptor tyrosine kinase 1.32846
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.32846
TPI1 triosephosphate isomerase 1 1.32756
ANXA2 annexin A2 1.32756
AR androgen receptor 1.32667
ALAS2 5'-aminolevulinate synthase 2 1.32428
CYBB cytochrome b-245, beta polypeptide 1.3228
UNG uracil-DNA glycosylase 1.32132
CDC25B cell division cycle 25B 1.31807
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.31807
S100A11 S100 calcium binding protein A11 1.31596
COL6A3 collagen, type VI, alpha 3 1.31596
CCNG1 cyclin G1 1.31536
DIABLO diablo, IAP-binding mitochondrial protein 1.31506
GSTA1 glutathione S-transferase alpha 1 1.31416
AIF1L allograft inflammatory factor 1-like 1.31357
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 1.31357
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.31297
MAP2K2 mitogen-activated protein kinase kinase 2 1.31297
BIRC2 baculoviral IAP repeat containing 2 1.31297
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.31267
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.31208
S100A6 S100 calcium binding protein A6 1.31208
PFKP phosphofructokinase, platelet 1.31178
PF4 platelet factor 4 1.31178
HDAC1 histone deacetylase 1 1.30911
ADRB2 adrenoceptor beta 2, surface 1.30881
BTG1 B-cell translocation gene 1, anti-proliferative 1.30604
NCOA1 nuclear receptor coactivator 1 1.30604
CREM cAMP responsive element modulator 1.30604
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.30604
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) 1.30482
PYGL phosphorylase, glycogen, liver 1.3039
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 1.3039
SRXN1 sulfiredoxin 1 1.3036
FNBP1 formin binding protein 1 1.30147
EGR3 early growth response 3 1.29996
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.29905
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.29812
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.29719
NDRG2 NDRG family member 2 1.29595
EFNB3 ephrin-B3 1.29595
BIN1 bridging integrator 1 1.29564
AK3 adenylate kinase 3 1.29564
SFXN1 sideroflexin 1 1.29564
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.29564
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.29564
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.2941
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.2941
CALCA calcitonin-related polypeptide alpha 1.29348
EGF epidermal growth factor 1.29194
TGFB2 transforming growth factor, beta 2 1.2898
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.28827
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.28827
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.28796
GSTA2 glutathione S-transferase alpha 2 1.28579
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.28549
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.28549
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.28518
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.28487
POU2F1 POU class 2 homeobox 1 1.28487
LBP lipopolysaccharide binding protein 1.28425
EEF2 eukaryotic translation elongation factor 2 1.28241
MKI67 marker of proliferation Ki-67 1.28058
ISG15 ISG15 ubiquitin-like modifier 1.28058
PLA1A phospholipase A1 member A 1.27936
EPRS glutamyl-prolyl-tRNA synthetase 1.27936
OTC ornithine carbamoyltransferase 1.27936
ACIN1 apoptotic chromatin condensation inducer 1 1.27936
TXNRD1 thioredoxin reductase 1 1.27813
CDKN2A cyclin-dependent kinase inhibitor 2A 1.27689
ACP5 acid phosphatase 5, tartrate resistant 1.27657
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.27564
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.27409
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.27286
CXCR4 chemokine (C-X-C motif) receptor 4 1.27193
AQP1 aquaporin 1 (Colton blood group) 1.27132
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.27132
CD36 CD36 molecule (thrombospondin receptor) 1.26978
CTSS cathepsin S 1.26947
VWF von Willebrand factor 1.26947
UBC ubiquitin C 1.26947
TKT transketolase 1.26947
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.26947
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.26947
PCDH7 protocadherin 7 1.26917
RBPMS RNA binding protein with multiple splicing 1.26917
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.26856
PDIA3 protein disulfide isomerase family A, member 3 1.26856
FKBP5 FK506 binding protein 5 1.26856
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.26794
IL12A interleukin 12A 1.26763
PTEN phosphatase and tensin homolog 1.26638
GDF15 growth differentiation factor 15 1.26638
CPT2 carnitine palmitoyltransferase 2 1.26576
BAD BCL2-associated agonist of cell death 1.26452
PDPK1 3-phosphoinositide dependent protein kinase 1 1.26421
LCN2 lipocalin 2 1.26329
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.26236
PDIA4 protein disulfide isomerase family A, member 4 1.26205
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.26113
GSTM3 glutathione S-transferase mu 3 (brain) 1.26113
DCXR dicarbonyl/L-xylulose reductase 1.25929
ISYNA1 inositol-3-phosphate synthase 1 1.25929
ASS1 argininosuccinate synthase 1 1.25868
STAT1 signal transducer and activator of transcription 1, 91kDa 1.25776
ACTB actin, beta 1.25682
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.25525
PRDX2 peroxiredoxin 2 1.25525
RAD50 RAD50 homolog (S. cerevisiae) 1.25525
IRF1 interferon regulatory factor 1 1.25525
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.25525
CPT1A carnitine palmitoyltransferase 1A (liver) 1.25494
PHYH phytanoyl-CoA 2-hydroxylase 1.25432
EPOR erythropoietin receptor 1.25432
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.25245
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.25183
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.25183
PRNP prion protein 1.24997
CHRM5 cholinergic receptor, muscarinic 5 1.24935
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.24935
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.24935
THNSL2 threonine synthase-like 2 (S. cerevisiae) 1.24905
TYK2 tyrosine kinase 2 1.24905
BCHE butyrylcholinesterase 1.24905
PCCB propionyl CoA carboxylase, beta polypeptide 1.24905
SATB1 SATB homeobox 1 1.24905
CAPN2 calpain 2, (m/II) large subunit 1.24843
HRAS Harvey rat sarcoma viral oncogene homolog 1.2475
IGFBP4 insulin-like growth factor binding protein 4 1.24496
ACAA2 acetyl-CoA acyltransferase 2 1.24496
AK1 adenylate kinase 1 1.24465
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.24465
FMO2 flavin containing monooxygenase 2 (non-functional) 1.24465
SREBF1 sterol regulatory element binding transcription factor 1 1.24401
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.24213
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.23993
RPS19 ribosomal protein S19 1.23993
TUBA4A tubulin, alpha 4a 1.23993
SQSTM1 sequestosome 1 1.23837
PTK2B protein tyrosine kinase 2 beta 1.23837
BTG3 BTG family, member 3 1.23552
APOC1 apolipoprotein C-I 1.23552
KIF3A kinesin family member 3A 1.2352
TMED9 transmembrane emp24 protein transport domain containing 9 1.2352
TRIM28 tripartite motif containing 28 1.2352
GATA3 GATA binding protein 3 1.23488
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.23424
SESN2 sestrin 2 1.23169
SAT1 spermidine/spermine N1-acetyltransferase 1 1.23169
MT1G metallothionein 1G 1.23074
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.22948
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.22948
HADH hydroxyacyl-CoA dehydrogenase 1.22821
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.22696
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.22632
CD86 CD86 molecule 1.22632
NINJ1 ninjurin 1 1.22632
SRM spermidine synthase 1.22632
TMEM97 transmembrane protein 97 1.22632
PENK proenkephalin 1.22469
PKM pyruvate kinase, muscle 1.22469
PRKCB protein kinase C, beta 1.22469
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.22177
ITGB5 integrin, beta 5 1.22177
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.22177
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.21855
MCAM melanoma cell adhesion molecule 1.21727
AHR aryl hydrocarbon receptor 1.21727
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.21727
GPR176 G protein-coupled receptor 176 1.21534
PTGES prostaglandin E synthase 1.21534
TUBG1 tubulin, gamma 1 1.21501
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.21501
ADM adrenomedullin 1.21468
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.21468
PLTP phospholipid transfer protein 1.21304
CXCL2 chemokine (C-X-C motif) ligand 2 1.21304
BDKRB1 bradykinin receptor B1 1.21304
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.21076
SFTPB surfactant protein B 1.20881
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 1.20848
FAM107A family with sequence similarity 107, member A 1.20848
ACACA acetyl-CoA carboxylase alpha 1.20751
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.20687
GADD45B growth arrest and DNA-damage-inducible, beta 1.20526
FXR2 fragile X mental retardation, autosomal homolog 2 1.2046
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.2046
HTRA1 HtrA serine peptidase 1 1.2046
KDR kinase insert domain receptor 1.20328
CXCL5 chemokine (C-X-C motif) ligand 5 1.20295
TNC tenascin C 1.20295
TSPO translocator protein (18kDa) 1.20295
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.20295
CCL4 chemokine (C-C motif) ligand 4 1.2013
GHR growth hormone receptor 1.19966
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.19672
NEFL neurofilament, light polypeptide 1.19672
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 1.19607
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 1.19607
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.19607
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.19607
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.19607
MAPK9 mitogen-activated protein kinase 9 1.19574
IRS1 insulin receptor substrate 1 1.19574
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.19379
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.19179
ANXA1 annexin A1 1.19113
CCNB2 cyclin B2 1.19113
CKB creatine kinase, brain 1.1908
MGST1 microsomal glutathione S-transferase 1 1.18882
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.18783
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.18783
BHLHE40 basic helix-loop-helix family, member e40 1.18783
G0S2 G0/G1 switch 2 1.18489
HBB hemoglobin, beta 1.18489
TEX261 testis expressed 261 1.18489
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 1.18424
MAP3K8 mitogen-activated protein kinase kinase kinase 8 1.18391
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.18391
INSIG1 insulin induced gene 1 1.18193
IL1RN interleukin 1 receptor antagonist 1.18193
FSHB follicle stimulating hormone, beta polypeptide 1.18093
ADIPOR2 adiponectin receptor 2 1.17993
DGAT1 diacylglycerol O-acyltransferase 1 1.17993
CYB5R3 cytochrome b5 reductase 3 1.17993
MAP2K1 mitogen-activated protein kinase kinase 1 1.17926
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.17926
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.17629
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.17596
UBE2C ubiquitin-conjugating enzyme E2C 1.17333
MSMO1 methylsterol monooxygenase 1 1.17333
NDRG1 N-myc downstream regulated 1 1.173
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.17268
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.17268
PDCD5 programmed cell death 5 1.17268
DPYSL3 dihydropyrimidinase-like 3 1.17268
PSIP1 PC4 and SFRS1 interacting protein 1 1.17268
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 1.17202
VCAN versican 1.17202
LMNA lamin A/C 1.17034
WNT4 wingless-type MMTV integration site family, member 4 1.16833
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.16833
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.16766
ABHD2 abhydrolase domain containing 2 1.167
MUT methylmalonyl CoA mutase 1.167
HPCAL1 hippocalcin-like 1 1.167
CRYAB crystallin, alpha B 1.16666
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.16666
LIAS lipoic acid synthetase 1.16633
HMHA1 histocompatibility (minor) HA-1 1.16633
ESR1 estrogen receptor 1 1.16533
CCL11 chemokine (C-C motif) ligand 11 1.165
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.165
TGIF1 TGFB-induced factor homeobox 1 1.16467
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.16203
RAD23A RAD23 homolog A (S. cerevisiae) 1.1617
HSDL2 hydroxysteroid dehydrogenase like 2 1.1617
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.1607
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.1607
NES nestin 1.1607
CD40LG CD40 ligand 1.1607
CAPN1 calpain 1, (mu/I) large subunit 1.1607
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.15933
CYB5A cytochrome b5 type A (microsomal) 1.15933
TRPM6 transient receptor potential cation channel, subfamily M, member 6 1.15763
HLA-DRA major histocompatibility complex, class II, DR alpha 1.15763
PER1 period circadian clock 1 1.15695
LCAT lecithin-cholesterol acyltransferase 1.15695
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.15661
F2R coagulation factor II (thrombin) receptor 1.15661
HMGB1 high mobility group box 1 1.15661
ASL argininosuccinate lyase 1.15627
EIF3A eukaryotic translation initiation factor 3, subunit A 1.15627
CA12 carbonic anhydrase XII 1.15627
FSCN1 fascin actin-bundling protein 1 1.15627
COL7A1 collagen, type VII, alpha 1 1.15627
FLT1 fms-related tyrosine kinase 1 1.15391
CCNE2 cyclin E2 1.15391
PRC1 protein regulator of cytokinesis 1 1.15324
SP1 Sp1 transcription factor 1.15156
LEPR leptin receptor 1.15156
CHEK1 checkpoint kinase 1 1.15156
ACSS2 acyl-CoA synthetase short-chain family member 2 1.15089
ABHD4 abhydrolase domain containing 4 1.15089
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.15089
SELL selectin L 1.14989
COL18A1 collagen, type XVIII, alpha 1 1.14954
PON2 paraoxonase 2 1.14954
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 1.14919
GSK3A glycogen synthase kinase 3 alpha 1.14541
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.14541
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.14541
UQCRC1 ubiquinol-cytochrome c reductase core protein I 1.14541
CDK7 cyclin-dependent kinase 7 1.14541
TFRC transferrin receptor 1.14438
CAV1 caveolin 1, caveolae protein, 22kDa 1.14302
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.14234
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 1.14098
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.1403
PABPC1 poly(A) binding protein, cytoplasmic 1 1.1403
COX2 1.1403
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 1.1403
EPCAM epithelial cell adhesion molecule 1.13895
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.13895
EFNA1 ephrin-A1 1.13895
GAST gastrin 1.13895
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.13895
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.13793
DDIT4 DNA-damage-inducible transcript 4 1.13689
FBXO32 F-box protein 32 1.13552
LIPC lipase, hepatic 1.13552
IGFBP5 insulin-like growth factor binding protein 5 1.13518
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.13518
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 1.13518
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.13279
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.13279
SBSPON somatomedin B and thrombospondin, type 1 domain containing 1.13245
DCAF8 DDB1 and CUL4 associated factor 8 1.13245
S100A10 S100 calcium binding protein A10 1.13177
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.13177
GLDC glycine dehydrogenase (decarboxylating) 1.13041
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.13041
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.13041
SLCO1B3 solute carrier organic anion transporter family, member 1B3 1.13041
KLK1 kallikrein 1 1.13041
EDNRA endothelin receptor type A 1.13007
FOSL1 FOS-like antigen 1 1.12906
CD83 CD83 molecule 1.12838
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.12838
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.12838
ENDOG endonuclease G 1.12564
SPON1 spondin 1, extracellular matrix protein 1.12564
DPYSL2 dihydropyrimidinase-like 2 1.12564
PGRMC1 progesterone receptor membrane component 1 1.12564
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.1253
ESD esterase D 1.1253
PALLD palladin, cytoskeletal associated protein 1.1253
KLF5 Kruppel-like factor 5 (intestinal) 1.12495
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.12495
LGALS3 lectin, galactoside-binding, soluble, 3 1.12495
STC2 stanniocalcin 2 1.12495
RPS6 ribosomal protein S6 1.12495
QPRT quinolinate phosphoribosyltransferase 1.12461
HBEGF heparin-binding EGF-like growth factor 1.12254
MME membrane metallo-endopeptidase 1.12185
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.12185
PDIA6 protein disulfide isomerase family A, member 6 1.12185
COX5A cytochrome c oxidase subunit Va 1.12082
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.12048
KMT2A lysine (K)-specific methyltransferase 2A 1.12048
PTPRD protein tyrosine phosphatase, receptor type, D 1.12048
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 1.12048
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.12014
PRKCD protein kinase C, delta 1.11911
PLCG1 phospholipase C, gamma 1 1.11843
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.11843
PLLP plasmolipin 1.11741
PRKCSH protein kinase C substrate 80K-H 1.11741
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.11741
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.11741
CD2AP CD2-associated protein 1.11741
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.11707
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.11606
IRF9 interferon regulatory factor 9 1.11606
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.11606
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.11571
CDC25A cell division cycle 25A 1.11501
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.11501
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) 1.11255
MRO maestro 1.11255
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.11255
CD40 CD40 molecule, TNF receptor superfamily member 5 1.11255
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.11186
BCL2L2 BCL2-like 2 1.11116
ZFP36L2 ZFP36 ring finger protein-like 2 1.11116
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.11116
IVNS1ABP influenza virus NS1A binding protein 1.11116
RAB31 RAB31, member RAS oncogene family 1.11116
CDC25C cell division cycle 25C 1.11011
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 1.11011
ECI2 enoyl-CoA delta isomerase 2 1.11011
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.10977
MYCBP MYC binding protein 1.10977
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.10838
COL4A1 collagen, type IV, alpha 1 1.10838
TIMP3 TIMP metallopeptidase inhibitor 3 1.10769
CFI complement factor I 1.10665
CALD1 caldesmon 1 1.10665
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.10527
SIGMAR1 sigma non-opioid intracellular receptor 1 1.10527
NOS1 nitric oxide synthase 1 (neuronal) 1.10388
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 1.10282
TRIM22 tripartite motif containing 22 1.10282
MED13L mediator complex subunit 13-like 1.10282
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1.10282
GPX2 glutathione peroxidase 2 1.10282
RFTN1 raftlin, lipid raft linker 1 1.10246
MSH3 mutS homolog 3 1.10246
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.10211
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.10211
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.10175
CCNE1 cyclin E1 1.10104
MT1A metallothionein 1A 1.09998
TSNAX translin-associated factor X 1.09998
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 1.09963
MARCKS myristoylated alanine-rich protein kinase C substrate 1.09892
S100B S100 calcium binding protein B 1.09892
KRT18 keratin 18, type I 1.09822
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.09822
MTUS1 microtubule associated tumor suppressor 1 1.09751
CSNK1A1 casein kinase 1, alpha 1 1.09751
ACKR3 atypical chemokine receptor 3 1.09751
TRAF2 TNF receptor-associated factor 2 1.09751
MT2A metallothionein 2A 1.09611
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.09576
RGS17 regulator of G-protein signaling 17 1.09576
PDYN prodynorphin 1.09576
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.09576
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.09576
LTF lactotransferrin 1.09576
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 1.09541
PBX2 pre-B-cell leukemia homeobox 2 1.09541
SLC44A1 solute carrier family 44 (choline transporter), member 1 1.09541
LZTFL1 leucine zipper transcription factor-like 1 1.09541
RXRA retinoid X receptor, alpha 1.09436
ANXA5 annexin A5 1.09332
LAMP2 lysosomal-associated membrane protein 2 1.09297
TOB1 transducer of ERBB2, 1 1.09297
AKR1D1 aldo-keto reductase family 1, member D1 1.09297
ACSL5 acyl-CoA synthetase long-chain family member 5 1.09297
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.09262
SIRT1 sirtuin 1 1.09262
DUSP6 dual specificity phosphatase 6 1.09119
COMT catechol-O-methyltransferase 1.09083
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.09047
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.0894
PCSK9 proprotein convertase subtilisin/kexin type 9 1.08868
GTF2H5 general transcription factor IIH, polypeptide 5 1.08868
CCAR1 cell division cycle and apoptosis regulator 1 1.08868
BCL6B B-cell CLL/lymphoma 6, member B 1.08868
MFN2 mitofusin 2 1.08868
TGM2 transglutaminase 2 1.08868
LMCD1 LIM and cysteine-rich domains 1 1.08868
WDR26 WD repeat domain 26 1.08868
TLR2 toll-like receptor 2 1.08868
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.08655
ERCC4 excision repair cross-complementation group 4 1.08407
MT1E metallothionein 1E 1.08407
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.08407
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.08407
ETHE1 ethylmalonic encephalopathy 1 1.08196
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.08196
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.08196
TMED5 transmembrane emp24 protein transport domain containing 5 1.08196
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 1.08196
GSTM2 glutathione S-transferase mu 2 (muscle) 1.08161
IER3 immediate early response 3 1.08161
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.08019
NCOA3 nuclear receptor coactivator 3 1.07983
BAG1 BCL2-associated athanogene 1.07983
HHEX hematopoietically expressed homeobox 1.07983
CSK c-src tyrosine kinase 1.07983
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.07947
CYR61 cysteine-rich, angiogenic inducer, 61 1.07947
CDKN3 cyclin-dependent kinase inhibitor 3 1.07732
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.07732
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.07553
SMOX spermine oxidase 1.07553
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.07553
MTTP microsomal triglyceride transfer protein 1.07553
ARHGAP5 Rho GTPase activating protein 5 1.07518
SLMO2 slowmo homolog 2 (Drosophila) 1.07482
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.07447
HSF1 heat shock transcription factor 1 1.07447
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.07163
C1QA complement component 1, q subcomponent, A chain 1.07163
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 1.07128
PITX2 paired-like homeodomain 2 1.06917
BAIAP2L1 BAI1-associated protein 2-like 1 1.06881
CD81 CD81 molecule 1.06881
NME7 NME/NM23 family member 7 1.06881
DPP3 dipeptidyl-peptidase 3 1.06881
GSTZ1 glutathione S-transferase zeta 1 1.06734
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.06734
TFPI2 tissue factor pathway inhibitor 2 1.06734
DUSP10 dual specificity phosphatase 10 1.06734
MVP major vault protein 1.06734
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 1.06734
TSHB thyroid stimulating hormone, beta 1.06552
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.06552
SUN2 Sad1 and UNC84 domain containing 2 1.06406
GATA5 GATA binding protein 5 1.06406
MMP1 matrix metallopeptidase 1 1.0637
GLB1L galactosidase, beta 1-like 1.0637
BRCA1 breast cancer 1, early onset 1.0637
ADCK2 aarF domain containing kinase 2 1.0637
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.06333
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.06333
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 1.06333
VIP vasoactive intestinal peptide 1.06333
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 1.06333
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.06297
LIF leukemia inhibitory factor 1.06261
CPN1 carboxypeptidase N, polypeptide 1 1.06261
BECN1 beclin 1, autophagy related 1.06261
MAP3K12 mitogen-activated protein kinase kinase kinase 12 1.06261
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.06261
HMGB2 high mobility group box 2 1.06261
CDC14B cell division cycle 14B 1.06261
TJP3 tight junction protein 3 1.06261
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 1.06261
HEXA hexosaminidase A (alpha polypeptide) 1.06261
WNK1 WNK lysine deficient protein kinase 1 1.06261
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.06261
ELOVL6 ELOVL fatty acid elongase 6 1.06261
SELM selenoprotein M 1.06261
ORM1 orosomucoid 1 1.05972
TSC22D3 TSC22 domain family, member 3 1.05972
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.05936
MAP2K3 mitogen-activated protein kinase kinase 3 1.05936
HOMER1 homer scaffolding protein 1 1.05936
NCL nucleolin 1.05936
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.05936
S1PR1 sphingosine-1-phosphate receptor 1 1.05936
ALPL alkaline phosphatase, liver/bone/kidney 1.05721
ATF2 activating transcription factor 2 1.05685
HSPA4 heat shock 70kDa protein 4 1.05685
SARS seryl-tRNA synthetase 1.05648
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.05648
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.05535
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.05535
THY1 Thy-1 cell surface antigen 1.05535
GLUD1 glutamate dehydrogenase 1 1.05535
AK4 adenylate kinase 4 1.05498
MGP matrix Gla protein 1.05386
IFT81 intraflagellar transport 81 1.05349
DHRS7B dehydrogenase/reductase (SDR family) member 7B 1.05312
CNR1 cannabinoid receptor 1 (brain) 1.05274
EFCAB7 EF-hand calcium binding domain 7 1.05274
ZHX3 zinc fingers and homeoboxes 3 1.05274
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.05126
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.05126
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.05126
SREBF2 sterol regulatory element binding transcription factor 2 1.05126
BRD2 bromodomain containing 2 1.05052
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.05052
HMGN3 high mobility group nucleosomal binding domain 3 1.05052
ZNF702P zinc finger protein 702, pseudogene 1.05015
HIBADH 3-hydroxyisobutyrate dehydrogenase 1.05015
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 1.05015
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.04831
ENO3 enolase 3 (beta, muscle) 1.04721
PGAM1 phosphoglycerate mutase 1 (brain) 1.04721
FDPS farnesyl diphosphate synthase 1.04538
DPYD dihydropyrimidine dehydrogenase 1.04538
ENO1 enolase 1, (alpha) 1.04427
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.04427
FLOT1 flotillin 1 1.04427
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1.04427
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.04427
YARS tyrosyl-tRNA synthetase 1.04427
CCND2 cyclin D2 1.04427
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.04352
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.04352
AURKA aurora kinase A 1.04276
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 1.04276
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.04276
RBM34 RNA binding motif protein 34 1.04276
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 1.04239
SIRT4 sirtuin 4 1.04201
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 1.04201
SYT13 synaptotagmin XIII 1.04201
ZFP36 ZFP36 ring finger protein 1.03976
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.03976
A2M alpha-2-macroglobulin 1.03976
GPX4 glutathione peroxidase 4 1.03976
FHL1 four and a half LIM domains 1 1.03939
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.03939
FGF21 fibroblast growth factor 21 1.03939
LEF1 lymphoid enhancer-binding factor 1 1.03939
TTK TTK protein kinase 1.03939
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.03939
UFD1L ubiquitin fusion degradation 1 like (yeast) 1.03827
REEP6 receptor accessory protein 6 1.03827
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 1.03827
H1FX H1 histone family, member X 1.03827
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.03827
BST2 bone marrow stromal cell antigen 2 1.03827
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.03789
INSR insulin receptor 1.03715
CBR1 carbonyl reductase 1 1.03715
CIRBP cold inducible RNA binding protein 1.03567
SDC2 syndecan 2 1.03567
ACAT1 acetyl-CoA acetyltransferase 1 1.03567
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.03567
MBP myelin basic protein 1.03456
RHOB ras homolog family member B 1.03419
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.03419
INHBA inhibin, beta A 1.03419
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.03271
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.03271
GRPR gastrin-releasing peptide receptor 1.03271
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 1.03271
CLCN4 chloride channel, voltage-sensitive 4 1.03235
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.03235
AQP4 aquaporin 4 1.03197
CUEDC2 CUE domain containing 2 1.03197
SART3 squamous cell carcinoma antigen recognized by T cells 3 1.03197
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.03197
PRLR prolactin receptor 1.03159
ALAS1 5'-aminolevulinate synthase 1 1.02896
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.02896
RORA RAR-related orphan receptor A 1.02821
POU5F1 POU class 5 homeobox 1 1.02821
MEF2C myocyte enhancer factor 2C 1.02821
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 1.02783
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.02746
C1QBP complement component 1, q subcomponent binding protein 1.02708
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 1.02708
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 1.02708
PKP2 plakophilin 2 1.02708
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.02708
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.02708
ELOVL3 ELOVL fatty acid elongase 3 1.02708
ETFDH electron-transferring-flavoprotein dehydrogenase 1.02708
CLIP1 CAP-GLY domain containing linker protein 1 1.02671
AQP3 aquaporin 3 (Gill blood group) 1.02634
CASP12 caspase 12 (gene/pseudogene) 1.02634
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.02634
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.02447
ACTA1 actin, alpha 1, skeletal muscle 1.02447
ADIPOQ adiponectin, C1Q and collagen domain containing 1.02299
ELMOD3 ELMO/CED-12 domain containing 3 1.02262
KLHL28 kelch-like family member 28 1.02262
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.02262
IL15RA interleukin 15 receptor, alpha 1.02262
HPS1 Hermansky-Pudlak syndrome 1 1.02262
RPAIN RPA interacting protein 1.02225
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.02225
MAP4 microtubule-associated protein 4 1.02151
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 1.02151
RHOQ ras homolog family member Q 1.02151
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.02151
RSRP1 arginine/serine-rich protein 1 1.02151
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.02114
BMP2 bone morphogenetic protein 2 1.02114
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.02077
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.02077
GLS glutaminase 1.02077
FABP4 fatty acid binding protein 4, adipocyte 1.01928
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.01852
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.01852
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 1.01701
KIF23 kinesin family member 23 1.01701
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.01663
STX3 syntaxin 3 1.01625
SCNN1G sodium channel, non voltage gated 1 gamma subunit 1.01625
DPYSL4 dihydropyrimidinase-like 4 1.01587
AVP arginine vasopressin 1.01587
IL1R1 interleukin 1 receptor, type I 1.01587
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.01587
DHFR dihydrofolate reductase 1.01587
AKR1C3 aldo-keto reductase family 1, member C3 1.01549
FKBP4 FK506 binding protein 4, 59kDa 1.01361
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.01324
TRIP6 thyroid hormone receptor interactor 6 1.01324
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 1.01324
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.01324
HDAC3 histone deacetylase 3 1.01099
SKAP2 src kinase associated phosphoprotein 2 1.01099
RIOK3 RIO kinase 3 1.01062
COTL1 coactosin-like F-actin binding protein 1 1.01062
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.01062
TJP1 tight junction protein 1 1.01062
CCS copper chaperone for superoxide dismutase 1.01062
F10 coagulation factor X 1.01025
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.01025