Malaria Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle. (Human Disease Ontology, DOID_12365)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D008288
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Genes

20 genes/proteins associated with the disease Malaria from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ICAM1 intercellular adhesion molecule 1 2.88009
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.88009
CD36 CD36 molecule (thrombospondin receptor) 2.88009
GYPC glycophorin C (Gerbich blood group) 2.88009
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 2.88009
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.88009
NOS2 nitric oxide synthase 2, inducible 2.88009
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.88009
HP haptoglobin 2.88009
TNF tumor necrosis factor 2.88009
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.88009
NCR3 natural cytotoxicity triggering receptor 3 2.88009
CISH cytokine inducible SH2-containing protein 2.88009
GYPA glycophorin A (MNS blood group) 2.88009
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.36476
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.13347
GSTP1 glutathione S-transferase pi 1 1.1122
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.04684