Malaria, Falciparum Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

126 genes associated with the Malaria, Falciparum phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADCY9 adenylate cyclase 9
ADGRE1 adhesion G protein-coupled receptor E1
ADRB2 adrenoceptor beta 2, surface
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOE apolipoprotein E
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
C6 complement component 6
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRP C-reactive protein, pentraxin-related
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DERL3 derlin 3
FAS Fas cell surface death receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOXO3 forkhead box O3
FOXP3 forkhead box P3
G6PD glucose-6-phosphate dehydrogenase
GBP7 guanylate binding protein 7
GCLC glutamate-cysteine ligase, catalytic subunit
GNAS GNAS complex locus
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GYPA glycophorin A (MNS blood group)
GYPB glycophorin B (MNS blood group)
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HP haptoglobin
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL12B interleukin 12B
IL13 interleukin 13
IL17RC interleukin 17 receptor C
IL17RD interleukin 17 receptor D
IL17RE interleukin 17 receptor E
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL3 interleukin 3
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IRF1 interferon regulatory factor 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DL5B killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LCT lactase
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIF-AS1 MIF antisense RNA 1
NCF1 neutrophil cytosolic factor 1
NCF1B neutrophil cytosolic factor 1B pseudogene
NCF1C neutrophil cytosolic factor 1C pseudogene
NCR3 natural cytotoxicity triggering receptor 3
NOS2 nitric oxide synthase 2, inducible
PECAM1 platelet/endothelial cell adhesion molecule 1
PROCR protein C receptor, endothelial
RAD50 RAD50 homolog (S. cerevisiae)
RTN3 reticulon 3
SELE selectin E
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SOD2 superoxide dismutase 2, mitochondrial
SPTB spectrin, beta, erythrocytic
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRB T cell receptor beta locus
TRIM5 tripartite motif containing 5
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9