MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes_Muscle - Striated (Skeletal) (MMHCC)_GSE1462 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1462
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Genes

600 genes differentially expressed during MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes_Muscle - Striated (Skeletal) (MMHCC)_GSE1462 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
FOSL2 FOS-like antigen 2 3.05868
CDH7 cadherin 7, type 2 3.042
MAPK8 mitogen-activated protein kinase 8 2.85655
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.84432
GPR32 G protein-coupled receptor 32 2.78276
GFRA2 GDNF family receptor alpha 2 2.76723
RAB5C RAB5C, member RAS oncogene family 2.74519
FLT1 fms-related tyrosine kinase 1 2.72636
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.71371
CCL8 chemokine (C-C motif) ligand 8 2.70016
ELOVL6 ELOVL fatty acid elongase 6 2.67872
PRSS22 protease, serine, 22 2.64846
VEZT vezatin, adherens junctions transmembrane protein 2.63818
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.58009
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.57946
CFL1 cofilin 1 (non-muscle) 2.57941
TRIP6 thyroid hormone receptor interactor 6 2.56664
MDK midkine (neurite growth-promoting factor 2) 2.54606
PAX6 paired box 6 2.54443
MMP11 matrix metallopeptidase 11 2.52096
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 2.5091
COLEC10 collectin sub-family member 10 (C-type lectin) 2.48744
IL1A interleukin 1, alpha 2.47307
RIN1 Ras and Rab interactor 1 2.45854
CCL13 chemokine (C-C motif) ligand 13 2.45497
ZNF224 zinc finger protein 224 2.42678
MAGEB2 melanoma antigen family B2 2.41353
SYCP1 synaptonemal complex protein 1 2.41345
LRRTM3 leucine rich repeat transmembrane neuronal 3 2.37993
CAMK4 calcium/calmodulin-dependent protein kinase IV 2.36283
IPO4 importin 4 2.35151
F2RL3 coagulation factor II (thrombin) receptor-like 3 2.30734
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.2865
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 2.27967
WDR76 WD repeat domain 76 2.27022
PLAC8 placenta-specific 8 2.25166
TSPAN9 tetraspanin 9 2.24885
DHFR dihydrofolate reductase 2.24727
ZSCAN16 zinc finger and SCAN domain containing 16 2.23584
ISOC2 isochorismatase domain containing 2 2.20539
PANX1 pannexin 1 2.20513
GSG1 germ cell associated 1 2.20238
COL11A2 collagen, type XI, alpha 2 2.19761
C1ORF106 chromosome 1 open reading frame 106 2.17582
CCNE2 cyclin E2 2.17419
FANCA Fanconi anemia, complementation group A 2.16729
MYO3A myosin IIIA 2.16476
MUC1 mucin 1, cell surface associated 2.14482
IGHD immunoglobulin heavy constant delta 2.14234
SIKE1 suppressor of IKBKE 1 2.1365
FCAR Fc fragment of IgA receptor 2.12209
IBSP integrin-binding sialoprotein 2.11266
TMEM176A transmembrane protein 176A 2.10736
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.10688
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.10466
LRP5 low density lipoprotein receptor-related protein 5 2.09284
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head) 2.08819
GPR137 G protein-coupled receptor 137 2.08272
DLC1 DLC1 Rho GTPase activating protein 2.07928
ADM2 adrenomedullin 2 2.07914
SKAP1 src kinase associated phosphoprotein 1 2.06988
PRIM2 primase, DNA, polypeptide 2 (58kDa) 2.04212
MIS18BP1 MIS18 binding protein 1 2.04208
APOL5 apolipoprotein L, 5 2.04109
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 2.03659
HOXB13 homeobox B13 2.02926
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.02098
ZC3H7B zinc finger CCCH-type containing 7B 2.01783
LY86 lymphocyte antigen 86 2.00129
MYO7B myosin VIIB 1.99214
CD247 CD247 molecule 1.99093
THY1 Thy-1 cell surface antigen 1.98817
PBX2 pre-B-cell leukemia homeobox 2 1.98155
CKAP2 cytoskeleton associated protein 2 1.9811
MOBP myelin-associated oligodendrocyte basic protein 1.97941
LINC01587 long intergenic non-protein coding RNA 1587 1.96878
ZWINT ZW10 interacting kinetochore protein 1.9633
GFPT2 glutamine-fructose-6-phosphate transaminase 2 1.96195
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.96102
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 1.95944
ITSN1 intersectin 1 (SH3 domain protein) 1.9486
C8ORF44 chromosome 8 open reading frame 44 1.93896
CCL5 chemokine (C-C motif) ligand 5 1.93851
NAT10 N-acetyltransferase 10 (GCN5-related) 1.93618
SH2D2A SH2 domain containing 2A 1.93511
TRAF1 TNF receptor-associated factor 1 1.93114
IL1RL1 interleukin 1 receptor-like 1 1.93067
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 1.90633
IL21 interleukin 21 1.90161
PRPF19 pre-mRNA processing factor 19 1.89813
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 1.8936
HSFX2 heat shock transcription factor family, X linked 2 1.88394
TRGV5 T cell receptor gamma variable 5 1.88225
LRRC17 leucine rich repeat containing 17 1.8759
REG3A regenerating islet-derived 3 alpha 1.87501
ZBTB17 zinc finger and BTB domain containing 17 1.87486
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 1.87284
HYPK huntingtin interacting protein K 1.86922
DAZAP1 DAZ associated protein 1 1.86876
LOC220077 dedicator of cytokinesis 1 pseudogene 1.86165
COMMD1 copper metabolism (Murr1) domain containing 1 1.86059
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.85953
KIAA1324 KIAA1324 1.84486
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 1.84408
CRISP1 cysteine-rich secretory protein 1 1.84399
CADPS Ca++-dependent secretion activator 1.83908
GVINP1 GTPase, very large interferon inducible pseudogene 1 1.83653
PVRIG poliovirus receptor related immunoglobulin domain containing 1.83565
NCR3 natural cytotoxicity triggering receptor 3 1.83244
SEPT4 septin 4 1.828
ARG1 arginase 1 1.82466
ZIM2 zinc finger, imprinted 2 1.80982
NXPH4 neurexophilin 4 1.80523
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 1.80429
TMED9 transmembrane emp24 protein transport domain containing 9 1.80417
MXD1 MAX dimerization protein 1 1.803
AMELX amelogenin, X-linked 1.80265
COL4A2 collagen, type IV, alpha 2 1.80256
KIF1A kinesin family member 1A 1.79908
ANKLE2 ankyrin repeat and LEM domain containing 2 1.79489
MYO9B myosin IXB 1.79397
LRRC8D leucine rich repeat containing 8 family, member D 1.79221
RPSAP20 ribosomal protein SA pseudogene 20 1.78743
CYP2A7P1 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1 1.78691
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.78509
CD79A CD79a molecule, immunoglobulin-associated alpha 1.78098
FAM155A family with sequence similarity 155, member A 1.77156
NSUN7 NOP2/Sun domain family, member 7 1.7708
NYX nyctalopin 1.76954
GSTM2 glutathione S-transferase mu 2 (muscle) 1.76587
PRSS55 protease, serine, 55 1.74861
GH1 growth hormone 1 1.74482
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 1.74431
TRO trophinin 1.74273
LAMB4 laminin, beta 4 1.74116
KRT1 keratin 1, type II 1.73893
LDLR low density lipoprotein receptor 1.73646
NPBWR2 neuropeptides B/W receptor 2 1.7361
CCL20 chemokine (C-C motif) ligand 20 1.7351
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.73509
FOXL2 forkhead box L2 1.72683
GBA glucosidase, beta, acid 1.72667
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.72587
ATF6B activating transcription factor 6 beta 1.72463
GNA13 guanine nucleotide binding protein (G protein), alpha 13 1.72232
ARID5A AT rich interactive domain 5A (MRF1-like) 1.72144
LOC51145 uncharacterized LOC51145 1.72
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.71772
VTCN1 V-set domain containing T cell activation inhibitor 1 1.71684
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.71497
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 1.71286
HNF4A hepatocyte nuclear factor 4, alpha 1.70852
SPA17 sperm autoantigenic protein 17 1.70788
LGALS9 lectin, galactoside-binding, soluble, 9 1.70328
KLK15 kallikrein-related peptidase 15 1.69793
POLQ polymerase (DNA directed), theta 1.69221
NEFH neurofilament, heavy polypeptide 1.69143
SMCP sperm mitochondria-associated cysteine-rich protein 1.68993
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 1.68822
ARG2 arginase 2 1.68733
PDCL phosducin-like 1.68176
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 1.68136
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 1.68131
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.67674
PWWP2A PWWP domain containing 2A 1.67591
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 1.67113
SH2D3C SH2 domain containing 3C 1.66893
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.66718
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.66603
PYCR1 pyrroline-5-carboxylate reductase 1 1.66239
CAMK2D calcium/calmodulin-dependent protein kinase II delta 1.66086
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 1.65963
FGFR2 fibroblast growth factor receptor 2 1.65787
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.65783
ERC1 ELKS/RAB6-interacting/CAST family member 1 1.65271
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.65004
C19ORF54 chromosome 19 open reading frame 54 1.65003
F11 coagulation factor XI 1.64927
TIFA TRAF-interacting protein with forkhead-associated domain 1.64732
MAT1A methionine adenosyltransferase I, alpha 1.64594
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 1.6452
HCRTR2 hypocretin (orexin) receptor 2 1.64483
KCTD20 potassium channel tetramerization domain containing 20 1.64065
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.63801
TRPV2 transient receptor potential cation channel, subfamily V, member 2 1.63531
MTRF1L mitochondrial translational release factor 1-like 1.63355
PLEK pleckstrin 1.63286
CTRC chymotrypsin C (caldecrin) 1.63015
C2 complement component 2 1.6279
MNT MAX network transcriptional repressor 1.62787
ZNF350 zinc finger protein 350 1.62529
PTCRA pre T-cell antigen receptor alpha 1.62285
BLM Bloom syndrome, RecQ helicase-like 1.62098
DMPK dystrophia myotonica-protein kinase 1.61965
LY6G6C lymphocyte antigen 6 complex, locus G6C 1.61874
BIN2 bridging integrator 2 1.61317
ADAMDEC1 ADAM-like, decysin 1 1.60948
EDAR ectodysplasin A receptor 1.60938
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.60606
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.60569
DHCR7 7-dehydrocholesterol reductase 1.60415
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 1.60415
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.60114
NXPH3 neurexophilin 3 1.59999
CREB3L1 cAMP responsive element binding protein 3-like 1 1.59995
GPC2 glypican 2 1.59961
RPP40 ribonuclease P/MRP 40kDa subunit 1.59844
ZC3H3 zinc finger CCCH-type containing 3 1.59725
G6PD glucose-6-phosphate dehydrogenase 1.59349
DBN1 drebrin 1 1.58807
CSK c-src tyrosine kinase 1.58708
DPP3 dipeptidyl-peptidase 3 1.58662
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.58356
PTPRA protein tyrosine phosphatase, receptor type, A 1.58353
PRSS3P2 protease, serine, 3 pseudogene 2 1.58352
SCYL2 SCY1-like 2 (S. cerevisiae) 1.57776
LDAH lipid droplet associated hydrolase 1.57726
CLEC11A C-type lectin domain family 11, member A 1.5768
C19ORF24 chromosome 19 open reading frame 24 1.57573
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 1.57425
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 1.57038
RPL22P22 ribosomal protein L22 pseudogene 22 1.56939
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.56799
DBF4 DBF4 zinc finger 1.5669
PRR14L proline rich 14-like 1.55869
SND1 staphylococcal nuclease and tudor domain containing 1 1.55573
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 1.55519
SIRT2 sirtuin 2 1.55426
GK2 glycerol kinase 2 1.55151
LAGE3 L antigen family, member 3 1.55005
REEP4 receptor accessory protein 4 1.54908
VTN vitronectin 1.54706
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 1.54539
LINC00597 long intergenic non-protein coding RNA 597 1.54536
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.54448
FNTB farnesyltransferase, CAAX box, beta 1.54078
HCFC1 host cell factor C1 1.53791
PELP1 proline, glutamate and leucine rich protein 1 1.53703
CDON cell adhesion associated, oncogene regulated 1.53701
ZGPAT zinc finger, CCCH-type with G patch domain 1.53613
DFNA5 deafness, autosomal dominant 5 1.53455
TAGLN3 transgelin 3 1.5316
ORAI3 ORAI calcium release-activated calcium modulator 3 1.53123
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.53046
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 1.53045
TMEM223 transmembrane protein 223 1.52866
CTSW cathepsin W 1.52606
ZFP30 ZFP30 zinc finger protein 1.52467
CDC7 cell division cycle 7 1.52455
NRL neural retina leucine zipper 1.52405
PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.52085
TATDN2 TatD DNase domain containing 2 1.52084
LIG1 ligase I, DNA, ATP-dependent 1.52043
IL6 interleukin 6 1.51898
PSG4 pregnancy specific beta-1-glycoprotein 4 1.51315
PRSS3 protease, serine, 3 1.51281
MRPS11P1 mitochondrial ribosomal protein S11 pseudogene 1 1.51073
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 1.5086
ADAM28 ADAM metallopeptidase domain 28 1.50788
PHTF1 putative homeodomain transcription factor 1 1.50761
CTNND2 catenin (cadherin-associated protein), delta 2 1.50454
PTHLH parathyroid hormone-like hormone 1.50438
KCNK10 potassium channel, two pore domain subfamily K, member 10 1.50277
HAND2 heart and neural crest derivatives expressed 2 1.50247
SLC39A4 solute carrier family 39 (zinc transporter), member 4 1.49969
PDIA4 protein disulfide isomerase family A, member 4 1.4982
CD2 CD2 molecule 1.49802
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.49534
NOP14-AS1 NOP14 antisense RNA 1 1.49382
RPL36AP52 ribosomal protein L36a pseudogene 1.49337
CAPN5 calpain 5 1.4923
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 1.49166
ARHGAP24 Rho GTPase activating protein 24 1.49147
GUCA1A guanylate cyclase activator 1A (retina) 1.49072
KIF6 kinesin family member 6 1.48961
PLXNA2 plexin A2 1.48919
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.4856
SSX4 synovial sarcoma, X breakpoint 4 1.48346
TMEM209 transmembrane protein 209 1.48143
AIM1L absent in melanoma 1-like 1.48029
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.47941
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.47704
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1.47648
CRABP2 cellular retinoic acid binding protein 2 1.47535
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.47436
OCA2 oculocutaneous albinism II 1.47237
MLANA melan-A 1.46861
KLRC2 killer cell lectin-like receptor subfamily C, member 2 1.46849
ADORA3 adenosine A3 receptor 1.46782
ZNF81 zinc finger protein 81 1.46732
SPIN1 spindlin 1 1.4665
HAVCR1 hepatitis A virus cellular receptor 1 1.4663
H2AFY2 H2A histone family, member Y2 1.46547
HPS1 Hermansky-Pudlak syndrome 1 1.46406
TXN thioredoxin 1.46186
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.46116
KIAA0101 KIAA0101 1.45748
CHP2 calcineurin-like EF-hand protein 2 1.4572
TBC1D16 TBC1 domain family, member 16 1.45538
BRPF1 bromodomain and PHD finger containing, 1 1.45345

decreased expression

Symbol Name Standardized Value
C17ORF53 chromosome 17 open reading frame 53 -3.81935
FOXL1 forkhead box L1 -2.85979
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) -2.73577
MUC16 mucin 16, cell surface associated -2.72946
TKTL1 transketolase-like 1 -2.72602
MAL mal, T-cell differentiation protein -2.61622
ZNF221 zinc finger protein 221 -2.61034
RAB4B RAB4B, member RAS oncogene family -2.56744
CDH4 cadherin 4, type 1, R-cadherin (retinal) -2.50698
DNAAF1 dynein, axonemal, assembly factor 1 -2.46941
ACPP acid phosphatase, prostate -2.44978
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) -2.4435
NPTX2 neuronal pentraxin II -2.37226
FOXD4L1 forkhead box D4-like 1 -2.31317
ARSF arylsulfatase F -2.27513
PNPLA2 patatin-like phospholipase domain containing 2 -2.27124
AATK apoptosis-associated tyrosine kinase -2.25223
CHRD chordin -2.22851
LMAN1L lectin, mannose-binding, 1 like -2.21631
CYB5R2 cytochrome b5 reductase 2 -2.19681
CSPG4P1Y chondroitin sulfate proteoglycan 4 pseudogene 1, Y-linked -2.17738
DNAL4 dynein, axonemal, light chain 4 -2.12572
STMN2 stathmin 2 -2.11358
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding) -2.11341
FRMPD4 FERM and PDZ domain containing 4 -2.10818
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding) -2.09899
FLJ22184 -2.09489
FCHO1 FCH domain only 1 -2.08088
ANTXR1 anthrax toxin receptor 1 -2.0522
KRT17 keratin 17, type I -2.05006
SSX5 synovial sarcoma, X breakpoint 5 -2.04415
HPD 4-hydroxyphenylpyruvate dioxygenase -2.00979
ERBB3 erb-b2 receptor tyrosine kinase 3 -1.98119
PPT2 palmitoyl-protein thioesterase 2 -1.96603
SAA3P serum amyloid A3 pseudogene -1.95302
SOX1 SRY (sex determining region Y)-box 1 -1.95275
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -1.9449
DKK3 dickkopf WNT signaling pathway inhibitor 3 -1.93713
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 -1.9368
CHD1L chromodomain helicase DNA binding protein 1-like -1.93663
PCDHB3 protocadherin beta 3 -1.91378
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -1.90813
SH3BP1 SH3-domain binding protein 1 -1.90139
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D -1.89305
PMS2P2 postmeiotic segregation increased 2 pseudogene 2 -1.87174
HBQ1 hemoglobin, theta 1 -1.86992
STRN striatin, calmodulin binding protein -1.85581
NRXN3 neurexin 3 -1.85277
PRB3 proline-rich protein BstNI subfamily 3 -1.8486
HIST1H2AG histone cluster 1, H2ag -1.84683
MXRA7 matrix-remodelling associated 7 -1.84325
MFSD7 major facilitator superfamily domain containing 7 -1.84248
HKDC1 hexokinase domain containing 1 -1.81211
NLK nemo-like kinase -1.81183
DMC1 DNA meiotic recombinase 1 -1.80565
CNN2 calponin 2 -1.78318
RCAN2 regulator of calcineurin 2 -1.78219
TNNI3 troponin I type 3 (cardiac) -1.77817
FGFR3 fibroblast growth factor receptor 3 -1.77419
FA2H fatty acid 2-hydroxylase -1.76944
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -1.7674
AIRE autoimmune regulator -1.76705
SIRT5 sirtuin 5 -1.76558
PCDHGA8 protocadherin gamma subfamily A, 8 -1.7638
KLHDC8A kelch domain containing 8A -1.75346
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -1.75312
DOC2A double C2-like domains, alpha -1.75303
NPR1 natriuretic peptide receptor 1 -1.75081
CLDN18 claudin 18 -1.74688
SH3GL3 SH3-domain GRB2-like 3 -1.74008
F2 coagulation factor II (thrombin) -1.7233
TOR4A torsin family 4, member A -1.71266
DMBT1 deleted in malignant brain tumors 1 -1.71051
HIST1H2AJ histone cluster 1, H2aj -1.70938
CCNJL cyclin J-like -1.69933
AGR2 anterior gradient 2 -1.69932
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -1.69389
APC2 adenomatosis polyposis coli 2 -1.69183
SFRP1 secreted frizzled-related protein 1 -1.68878
PPY pancreatic polypeptide -1.6879
DEFB4A defensin, beta 4A -1.68515
MYO16 myosin XVI -1.68226
ZNF35 zinc finger protein 35 -1.67929
CORO1B coronin, actin binding protein, 1B -1.67747
CADM4 cell adhesion molecule 4 -1.67594
PRSS8 protease, serine, 8 -1.67366
GNB5 guanine nucleotide binding protein (G protein), beta 5 -1.66686
APCS amyloid P component, serum -1.66029
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -1.66012
C14ORF2 chromosome 14 open reading frame 2 -1.65376
PPP1R13B protein phosphatase 1, regulatory subunit 13B -1.64649
GRIK5 glutamate receptor, ionotropic, kainate 5 -1.64227
NOTCH3 notch 3 -1.63908
AOX1 aldehyde oxidase 1 -1.63826
HAB1 B1 for mucin -1.62886
MOS v-mos Moloney murine sarcoma viral oncogene homolog -1.62835
LENEP lens epithelial protein -1.6276
EPHX2 epoxide hydrolase 2, cytoplasmic -1.6271
COL9A3 collagen, type IX, alpha 3 -1.62633
CAV2 caveolin 2 -1.61197
SAA2 serum amyloid A2 -1.61093
ZNF518A zinc finger protein 518A -1.61082
TPX2 TPX2, microtubule-associated -1.60708
SIGLEC9 sialic acid binding Ig-like lectin 9 -1.59681
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -1.59261
TMEM100 transmembrane protein 100 -1.5907
MNX1 motor neuron and pancreas homeobox 1 -1.59058
AIF1 allograft inflammatory factor 1 -1.59019
PRKCG protein kinase C, gamma -1.58279
TP53BP1 tumor protein p53 binding protein 1 -1.58188
CDH19 cadherin 19, type 2 -1.57781
ANAPC13 anaphase promoting complex subunit 13 -1.5773
SLAMF1 signaling lymphocytic activation molecule family member 1 -1.57635
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -1.57628
UBASH3A ubiquitin associated and SH3 domain containing A -1.57413
INS insulin -1.57169
ZBTB3 zinc finger and BTB domain containing 3 -1.57156
SETD4 SET domain containing 4 -1.56937
CSRP1 cysteine and glycine-rich protein 1 -1.56608
CRTAC1 cartilage acidic protein 1 -1.56455
NR4A3 nuclear receptor subfamily 4, group A, member 3 -1.56187
MED9 mediator complex subunit 9 -1.56032
IL21R interleukin 21 receptor -1.56024
NSD1 nuclear receptor binding SET domain protein 1 -1.5514
ZBTB39 zinc finger and BTB domain containing 39 -1.54925
KEL Kell blood group, metallo-endopeptidase -1.5482
CNTNAP2 contactin associated protein-like 2 -1.53881
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -1.53776
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -1.53578
GPR162 G protein-coupled receptor 162 -1.5316
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -1.52712
EHD3 EH-domain containing 3 -1.52254
MMP24 matrix metallopeptidase 24 (membrane-inserted) -1.51995
RPS12 ribosomal protein S12 -1.51683
TEX11 testis expressed 11 -1.51256
ADGRG3 adhesion G protein-coupled receptor G3 -1.50971
GREM1 gremlin 1, DAN family BMP antagonist -1.50671
HOXB5 homeobox B5 -1.5062
HOXD12 homeobox D12 -1.50515
IL23R interleukin 23 receptor -1.50393
PRX periaxin -1.49784
MEST mesoderm specific transcript -1.49369
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -1.49314
MTMR11 myotubularin related protein 11 -1.48907
THEG theg spermatid protein -1.48751
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 -1.48724
HRH3 histamine receptor H3 -1.48616
GRIA1 glutamate receptor, ionotropic, AMPA 1 -1.4835
SRPR signal recognition particle receptor (docking protein) -1.48321
CES1 carboxylesterase 1 -1.47509
HIST1H3F histone cluster 1, H3f -1.47334
TNNC1 troponin C type 1 (slow) -1.46861
ZNF365 zinc finger protein 365 -1.46837
TSPAN5 tetraspanin 5 -1.46403
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -1.46392
FABP1 fatty acid binding protein 1, liver -1.46359
PARP3 poly (ADP-ribose) polymerase family, member 3 -1.46063
STMN4 stathmin-like 4 -1.45921
PCDHGA11 protocadherin gamma subfamily A, 11 -1.45822
LOC254896 uncharacterized LOC254896 -1.45642
NCKIPSD NCK interacting protein with SH3 domain -1.45585
C1ORF54 chromosome 1 open reading frame 54 -1.45559
SLC12A9 solute carrier family 12, member 9 -1.45396
IL12A interleukin 12A -1.44754
GPR22 G protein-coupled receptor 22 -1.44722
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -1.44392
APOA2 apolipoprotein A-II -1.44316
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -1.44215
WNT6 wingless-type MMTV integration site family, member 6 -1.43988
MSX2 msh homeobox 2 -1.43928
HBA2 hemoglobin, alpha 2 -1.43897
IL9R interleukin 9 receptor -1.43875
CRP C-reactive protein, pentraxin-related -1.43657
PLXNB1 plexin B1 -1.4296
CALML5 calmodulin-like 5 -1.42801
APOC4 apolipoprotein C-IV -1.42471
PRLH prolactin releasing hormone -1.42466
MRPL4 mitochondrial ribosomal protein L4 -1.42053
LUZP2 leucine zipper protein 2 -1.4184
KSR1 kinase suppressor of ras 1 -1.41744
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 -1.41672
COX6C cytochrome c oxidase subunit VIc -1.41444
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.41335
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) -1.40957
MTA2 metastasis associated 1 family, member 2 -1.40518
TULP2 tubby like protein 2 -1.40382
ZNF236 zinc finger protein 236 -1.40068
ITPK1 inositol-tetrakisphosphate 1-kinase -1.40035
LGALS1 lectin, galactoside-binding, soluble, 1 -1.39997
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -1.39962
FAM83E family with sequence similarity 83, member E -1.39866
URM1 ubiquitin related modifier 1 -1.39349
DTX4 deltex 4, E3 ubiquitin ligase -1.3903
ADAM8 ADAM metallopeptidase domain 8 -1.3853
FBXL7 F-box and leucine-rich repeat protein 7 -1.38141
WNT11 wingless-type MMTV integration site family, member 11 -1.38116
C16ORF71 chromosome 16 open reading frame 71 -1.3794
PHF14 PHD finger protein 14 -1.37784
BDKRB2 bradykinin receptor B2 -1.37364
NOS1 nitric oxide synthase 1 (neuronal) -1.37233
CTRL chymotrypsin-like -1.37054
NSF N-ethylmaleimide-sensitive factor -1.36851
JPH2 junctophilin 2 -1.36758
CDK6 cyclin-dependent kinase 6 -1.36492
TM6SF2 transmembrane 6 superfamily member 2 -1.36354
MTMR7 myotubularin related protein 7 -1.36088
PAQR5 progestin and adipoQ receptor family member V -1.35873
HMBS hydroxymethylbilane synthase -1.3585
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -1.3574
GOLGA6A golgin A6 family, member A -1.35676
IGSF3 immunoglobulin superfamily, member 3 -1.35632
PLLP plasmolipin -1.35524
UQCRC1 ubiquinol-cytochrome c reductase core protein I -1.35432
SOD3 superoxide dismutase 3, extracellular -1.35063
TPO thyroid peroxidase -1.34911
CCDC6 coiled-coil domain containing 6 -1.34849
RAB32 RAB32, member RAS oncogene family -1.34821
WFDC1 WAP four-disulfide core domain 1 -1.34596
IGFBP6 insulin-like growth factor binding protein 6 -1.34494
UMPS uridine monophosphate synthetase -1.34429
HOOK2 hook microtubule-tethering protein 2 -1.34353
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 -1.3435
FOXD1 forkhead box D1 -1.34169
RAB11FIP5 RAB11 family interacting protein 5 (class I) -1.33772
CANT1 calcium activated nucleotidase 1 -1.33721
LINC00339 long intergenic non-protein coding RNA 339 -1.33672
FGF16 fibroblast growth factor 16 -1.33658
ANAPC15 anaphase promoting complex subunit 15 -1.3365
EDA ectodysplasin A -1.33524
ACOT7 acyl-CoA thioesterase 7 -1.33485
PODNL1 podocan-like 1 -1.33449
KIAA1467 KIAA1467 -1.33419
ZNF764 zinc finger protein 764 -1.33333
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -1.33265
SALL2 spalt-like transcription factor 2 -1.33238
SPPL2B signal peptide peptidase like 2B -1.33237
ICAM1 intercellular adhesion molecule 1 -1.3293
ADAM3B ADAM metallopeptidase domain 3B (pseudogene) -1.32662
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) -1.32635
CDHR1 cadherin-related family member 1 -1.32441
TEF thyrotrophic embryonic factor -1.3237
RNF10 ring finger protein 10 -1.32352
SRCAP Snf2-related CREBBP activator protein -1.31991
ACSS3 acyl-CoA synthetase short-chain family member 3 -1.31861
MASP2 mannan-binding lectin serine peptidase 2 -1.31705
SNTG1 syntrophin, gamma 1 -1.31525
SOX10 SRY (sex determining region Y)-box 10 -1.31257
ADGRB3 adhesion G protein-coupled receptor B3 -1.31246
SLN sarcolipin -1.31015
DRD1 dopamine receptor D1 -1.30718
SEC14L4 SEC14-like 4 (S. cerevisiae) -1.30057
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -1.30039
A4GNT alpha-1,4-N-acetylglucosaminyltransferase -1.30013
ACTA1 actin, alpha 1, skeletal muscle -1.29972
SDK2 sidekick cell adhesion molecule 2 -1.29966
PRH1 proline-rich protein HaeIII subfamily 1 -1.298
FN1 fibronectin 1 -1.29716
HLA-DOA major histocompatibility complex, class II, DO alpha -1.29652
LMAN1 lectin, mannose-binding, 1 -1.29596
GCM1 glial cells missing homolog 1 (Drosophila) -1.29528
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 -1.29524
LSM12 LSM12 homolog (S. cerevisiae) -1.29496
COL17A1 collagen, type XVII, alpha 1 -1.29317
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -1.29032
HGFAC HGF activator -1.28891
ZBTB8B zinc finger and BTB domain containing 8B -1.28834
ACTA2 actin, alpha 2, smooth muscle, aorta -1.28783
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -1.2866
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -1.28611
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 -1.28495
HBB hemoglobin, beta -1.28323
ISYNA1 inositol-3-phosphate synthase 1 -1.28253
CRYBA1 crystallin, beta A1 -1.28086
TLR4 toll-like receptor 4 -1.27949
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -1.27843
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.27753
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -1.27718
RPL23A ribosomal protein L23a -1.27595
ST14 suppression of tumorigenicity 14 (colon carcinoma) -1.27267
UNGP2 uracil-DNA glycosylase pseudogene 2 -1.27265
C19ORF40 chromosome 19 open reading frame 40 -1.27201
TMEM59L transmembrane protein 59-like -1.27015
MUC5B mucin 5B, oligomeric mucus/gel-forming -1.26514
TSPAN14 tetraspanin 14 -1.26491
ALDOA aldolase A, fructose-bisphosphate -1.26397
SCN11A sodium channel, voltage gated, type XI alpha subunit -1.26348
CBR3 carbonyl reductase 3 -1.26332
PRTN3 proteinase 3 -1.26311
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -1.26266
SLIT3 slit homolog 3 (Drosophila) -1.26256
ZNF202 zinc finger protein 202 -1.26249
SIDT2 SID1 transmembrane family, member 2 -1.26234
GAGE12I G antigen 12I -1.26183
MLPH melanophilin -1.2618
TCL1A T-cell leukemia/lymphoma 1A -1.26129
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -1.26025
KLF7 Kruppel-like factor 7 (ubiquitous) -1.26012
RNF130 ring finger protein 130 -1.25752
THBS1 thrombospondin 1 -1.25683
OSBP2 oxysterol binding protein 2 -1.25487