MDA-MB-453 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

590 genes with high or low expression in MDA-MB-453 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SEC16A SEC16 homolog A (S. cerevisiae) 3.58281
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 3.57076
INPP5J inositol polyphosphate-5-phosphatase J 3.46691
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.44098
TMEM87A transmembrane protein 87A 3.0517
FGFR4 fibroblast growth factor receptor 4 3.05037
CALML5 calmodulin-like 5 3.00014
SGSM3 small G protein signaling modulator 3 2.97928
DCAF4 DDB1 and CUL4 associated factor 4 2.92832
TACR2 tachykinin receptor 2 2.91972
INTS6 integrator complex subunit 6 2.8927
CDR2L cerebellar degeneration-related protein 2-like 2.85483
DALRD3 DALR anticodon binding domain containing 3 2.83121
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.82607
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 2.78207
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.75229
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 2.72867
DCXR dicarbonyl/L-xylulose reductase 2.72303
GRB2 growth factor receptor-bound protein 2 2.71487
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.70417
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 2.68591
NPDC1 neural proliferation, differentiation and control, 1 2.6859
HELZ helicase with zinc finger 2.67831
INSIG2 insulin induced gene 2 2.63477
HOOK2 hook microtubule-tethering protein 2 2.62551
TGFB3 transforming growth factor, beta 3 2.61673
CRAT carnitine O-acetyltransferase 2.60553
PLXNA3 plexin A3 2.56629
ICT1 immature colon carcinoma transcript 1 2.56595
GPD1L glycerol-3-phosphate dehydrogenase 1-like 2.54676
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.5205
AR androgen receptor 2.47512
CLCA2 chloride channel accessory 2 2.4687
F8A1 coagulation factor VIII-associated 1 2.46706
SIX2 SIX homeobox 2 2.46425
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.46393
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.46188
TRIM3 tripartite motif containing 3 2.44593
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 2.42692
ZNF688 zinc finger protein 688 2.41718
EMD emerin 2.39938
RHOB ras homolog family member B 2.39351
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.38907
RAB4A RAB4A, member RAS oncogene family 2.3846
KCTD2 potassium channel tetramerization domain containing 2 2.37489
TAZ tafazzin 2.35881
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.35368
TRIP11 thyroid hormone receptor interactor 11 2.34894
ZNF768 zinc finger protein 768 2.34543
SREBF1 sterol regulatory element binding transcription factor 1 2.34005
ARFIP2 ADP-ribosylation factor interacting protein 2 2.32015
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.31601
HIST1H3D histone cluster 1, H3d 2.29983
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 2.29836
KIAA0485 uncharacterized LOC57235 2.28179
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 2.25739
GGPS1 geranylgeranyl diphosphate synthase 1 2.25402
OAZ3 ornithine decarboxylase antizyme 3 2.25387
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.23397
FOXP1 forkhead box P1 2.23062
HLF hepatic leukemia factor 2.22427
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.22412
TTC9 tetratricopeptide repeat domain 9 2.22153
UBL4A ubiquitin-like 4A 2.22052
CDSN corneodesmosin 2.21367
SUMO4 small ubiquitin-like modifier 4 2.20294
HIST1H2BG histone cluster 1, H2bg 2.1943
HIST1H2AE histone cluster 1, H2ae 2.19405
MIA3 melanoma inhibitory activity family, member 3 2.17879
FAM3A family with sequence similarity 3, member A 2.17411
SPDEF SAM pointed domain containing ETS transcription factor 2.14222
FOXA1 forkhead box A1 2.13867
FHOD1 formin homology 2 domain containing 1 2.12307
LGALS8 lectin, galactoside-binding, soluble, 8 2.12236
GOLGA4 golgin A4 2.11983
TBC1D10B TBC1 domain family, member 10B 2.11592
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.09632
HK2 hexokinase 2 2.08352
ZNF692 zinc finger protein 692 2.08057
FAM50A family with sequence similarity 50, member A 2.07805
TMEM80 transmembrane protein 80 2.07419
CCDC47 coiled-coil domain containing 47 2.05928
IFT27 intraflagellar transport 27 2.05552
MTFR1 mitochondrial fission regulator 1 2.05011
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.04796
NUP85 nucleoporin 85kDa 2.03027
TSC22D3 TSC22 domain family, member 3 2.02812
IRX5 iroquois homeobox 5 2.02722
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.02231
ADCY6 adenylate cyclase 6 2.00799
PIP prolactin-induced protein 2.0073
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 1.99844
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 1.99716
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.99291
HOXA7 homeobox A7 1.98436
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.98277
VBP1 von Hippel-Lindau binding protein 1 1.97791
SPOP speckle-type POZ protein 1.97495
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 1.97258
DBP D site of albumin promoter (albumin D-box) binding protein 1.96712
HIST1H3H histone cluster 1, H3h 1.96656
DIP interstitial pneumonitis, desquamative, familial 1.96487
SYCP2 synaptonemal complex protein 2 1.96262
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 1.96212
KAT7 K(lysine) acetyltransferase 7 1.94493
BPTF bromodomain PHD finger transcription factor 1.9328
GPI glucose-6-phosphate isomerase 1.93248
SLTM SAFB-like, transcription modulator 1.92973
HIST2H2BE histone cluster 2, H2be 1.92493
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.90965
CLEC3B C-type lectin domain family 3, member B 1.89924
GSTT1 glutathione S-transferase theta 1 1.89279
BRD1 bromodomain containing 1 1.89079
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 1.88069
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.86864
GMPPA GDP-mannose pyrophosphorylase A 1.86064
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 1.85616
HIST1H4F histone cluster 1, H4f 1.85282
FICD FIC domain containing 1.85064
RAB33B RAB33B, member RAS oncogene family 1.84489
HIST3H2A histone cluster 3, H2a 1.84248
TESK1 testis-specific kinase 1 1.83675
KAT6B K(lysine) acetyltransferase 6B 1.82997
PER3 period circadian clock 3 1.82804
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 1.8232
PAQR6 progestin and adipoQ receptor family member VI 1.82006
SREBF2 sterol regulatory element binding transcription factor 2 1.81792
PNPLA2 patatin-like phospholipase domain containing 2 1.81235
MTMR3 myotubularin related protein 3 1.80755
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.79893
PRPF3 pre-mRNA processing factor 3 1.7975
PPP1R3D protein phosphatase 1, regulatory subunit 3D 1.79327
ANAPC2 anaphase promoting complex subunit 2 1.79186
GOLGA5 golgin A5 1.79185
LRRC31 leucine rich repeat containing 31 1.78803
CREB3 cAMP responsive element binding protein 3 1.78769
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 1.7869
PHKB phosphorylase kinase, beta 1.78509
VCP valosin containing protein 1.77821
ACBD3 acyl-CoA binding domain containing 3 1.77555
HOXC11 homeobox C11 1.77541
PPP4C protein phosphatase 4, catalytic subunit 1.77267
SLC39A1 solute carrier family 39 (zinc transporter), member 1 1.77126
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 1.76645
SEC23B Sec23 homolog B (S. cerevisiae) 1.75868
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.74137
SBNO2 strawberry notch homolog 2 (Drosophila) 1.7381
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.73754
EP300 E1A binding protein p300 1.73501
ASCC2 activating signal cointegrator 1 complex subunit 2 1.73271
KLHL28 kelch-like family member 28 1.73238
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.73139
NVL nuclear VCP-like 1.72041
KIF22 kinesin family member 22 1.71974
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.71686
HILPDA hypoxia inducible lipid droplet-associated 1.71637
SPHAR S-phase response (cyclin related) 1.71492
RNPEP arginyl aminopeptidase (aminopeptidase B) 1.71479
TNK2 tyrosine kinase, non-receptor, 2 1.71195
IP6K2 inositol hexakisphosphate kinase 2 1.70827
WWP1 WW domain containing E3 ubiquitin protein ligase 1 1.70762
ARF1 ADP-ribosylation factor 1 1.70472
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 1.70442
MON2 MON2 homolog (S. cerevisiae) 1.70252
COPG1 coatomer protein complex, subunit gamma 1 1.69656
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.69376
SORD sorbitol dehydrogenase 1.69179
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.69041
CCNG2 cyclin G2 1.68839
EHMT1 euchromatic histone-lysine N-methyltransferase 1 1.68178
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.68079
UBE3A ubiquitin protein ligase E3A 1.66908
XBP1 X-box binding protein 1 1.669
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 1.66572
CTAGE5 CTAGE family, member 5 1.66392
INHA inhibin, alpha 1.66254
SPG11 spastic paraplegia 11 (autosomal recessive) 1.65868
ADCY2 adenylate cyclase 2 (brain) 1.65576
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.65406
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.65265
DNASE1L1 deoxyribonuclease I-like 1 1.65217
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) 1.6508
FLII flightless I homolog (Drosophila) 1.64738
TOB1 transducer of ERBB2, 1 1.64704
TMEM134 transmembrane protein 134 1.64218
PRCC papillary renal cell carcinoma (translocation-associated) 1.64093
TUBGCP2 tubulin, gamma complex associated protein 2 1.64005
SLC2A4RG SLC2A4 regulator 1.63949
DHRS12 dehydrogenase/reductase (SDR family) member 12 1.63817
TMEM135 transmembrane protein 135 1.63408
ZMYM5 zinc finger, MYM-type 5 1.63024
MAN1B1 mannosidase, alpha, class 1B, member 1 1.62732
PLEKHA6 pleckstrin homology domain containing, family A member 6 1.62675
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 1.62259
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 1.62038
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.61913
RYBP RING1 and YY1 binding protein 1.61335
HRAS Harvey rat sarcoma viral oncogene homolog 1.61214
HIST1H2AG histone cluster 1, H2ag 1.61097
YBX2 Y box binding protein 2 1.60873
AZGP1 alpha-2-glycoprotein 1, zinc-binding 1.60871
GORASP1 golgi reassembly stacking protein 1, 65kDa 1.60827
ANGEL1 angel homolog 1 (Drosophila) 1.60818
GUK1 guanylate kinase 1 1.60638
CLN3 ceroid-lipofuscinosis, neuronal 3 1.60555
HIST1H4H histone cluster 1, H4h 1.60316
NT5C 5', 3'-nucleotidase, cytosolic 1.60212
SEC14L5 SEC14-like 5 (S. cerevisiae) 1.60136
CPEB3 cytoplasmic polyadenylation element binding protein 3 1.59966
EGLN3 egl-9 family hypoxia-inducible factor 3 1.59517
KDM3A lysine (K)-specific demethylase 3A 1.59382
TMEM63A transmembrane protein 63A 1.59104
ZNF75D zinc finger protein 75D 1.59083
PRR14 proline rich 14 1.58751
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 1.5854
LIG3 ligase III, DNA, ATP-dependent 1.5849
N4BP2L2-IT2 N4BPL2 intronic transcript 2 1.58487
SERF2 small EDRK-rich factor 2 1.58017
UBE2O ubiquitin-conjugating enzyme E2O 1.57694
RLF rearranged L-myc fusion 1.57402
GSK3B glycogen synthase kinase 3 beta 1.56673
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 1.56553
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.56514
YIPF1 Yip1 domain family, member 1 1.55195
APTX aprataxin 1.55149
G6PD glucose-6-phosphate dehydrogenase 1.54805
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.54329
COPE coatomer protein complex, subunit epsilon 1.54307
CASKIN2 CASK interacting protein 2 1.54032
DKFZP586I1420 uncharacterized protein DKFZp586I1420 1.54004
NBEAL2 neurobeachin-like 2 1.53895
PRODH proline dehydrogenase (oxidase) 1 1.53653
GHR growth hormone receptor 1.5349
AKAP8L A kinase (PRKA) anchor protein 8-like 1.53338
ERO1L ERO1-like (S. cerevisiae) 1.53236
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 1.52841
INHBB inhibin, beta B 1.52652
ACADSB acyl-CoA dehydrogenase, short/branched chain 1.52385
TRPS1 trichorhinophalangeal syndrome I 1.52256
N4BP2L2 NEDD4 binding protein 2-like 2 1.52205
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 1.51797
PBRM1 polybromo 1 1.5158
ARID4B AT rich interactive domain 4B (RBP1-like) 1.51048
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.50909
EGLN1 egl-9 family hypoxia-inducible factor 1 1.50896
SLC10A3 solute carrier family 10, member 3 1.50669
MCM3AP minichromosome maintenance complex component 3 associated protein 1.50534
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.50493
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.49577
FTSJ3 FtsJ homolog 3 (E. coli) 1.49396
AGO2 argonaute RISC catalytic component 2 1.49343
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 1.49216
MNX1 motor neuron and pancreas homeobox 1 1.49151
PLCB4 phospholipase C, beta 4 1.49058
KCTD3 potassium channel tetramerization domain containing 3 1.48957
SLC16A6 solute carrier family 16, member 6 1.48913
HOXC10 homeobox C10 1.48855
COQ6 coenzyme Q6 monooxygenase 1.48662
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.48524
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 1.484
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 1.48374
CYB561 cytochrome b561 1.48218
HIRIP3 HIRA interacting protein 3 1.48144
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.47893
IL17RC interleukin 17 receptor C 1.47304
CERS6 ceramide synthase 6 1.47172
ERBB2 erb-b2 receptor tyrosine kinase 2 1.471
NXF1 nuclear RNA export factor 1 1.46977
FBRS fibrosin 1.4688
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 1.46614
FAM179B family with sequence similarity 179, member B 1.4661
CDK5RAP3 CDK5 regulatory subunit associated protein 3 1.46463
PLAC1 placenta-specific 1 1.46394
PAPOLA poly(A) polymerase alpha 1.46109
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 1.46029
TMEM104 transmembrane protein 104 1.45637
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 1.4554
SIDT1 SID1 transmembrane family, member 1 1.45458
ZNF672 zinc finger protein 672 1.45304
SRP54 signal recognition particle 54kDa 1.45093
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 1.45075
FNBP1L formin binding protein 1-like 1.45062
IGFBP5 insulin-like growth factor binding protein 5 1.44887
CEP104 centrosomal protein 104kDa 1.4428
RANBP9 RAN binding protein 9 1.44275
PRLR prolactin receptor 1.4366
OSBPL2 oxysterol binding protein-like 2 1.43586
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 1.43529
GDI1 GDP dissociation inhibitor 1 1.43372
ZCCHC2 zinc finger, CCHC domain containing 2 1.4328
KCTD15 potassium channel tetramerization domain containing 15 1.42993
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.42958
PXMP4 peroxisomal membrane protein 4, 24kDa 1.42867
EHF ets homologous factor 1.42153
NEK4 NIMA-related kinase 4 1.42145
ILVBL ilvB (bacterial acetolactate synthase)-like 1.42025
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 1.41982
COQ9 coenzyme Q9 1.41932

low expression

Symbol Name Standardized Value
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -3.53725
SORBS3 sorbin and SH3 domain containing 3 -3.51165
TSPAN3 tetraspanin 3 -3.43487
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -3.2171
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -3.11107
ITGB8 integrin, beta 8 -2.96359
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.81369
CTSC cathepsin C -2.7651
HOMER2 homer scaffolding protein 2 -2.72484
COX5A cytochrome c oxidase subunit Va -2.71988
AKAP13 A kinase (PRKA) anchor protein 13 -2.71177
CALHM2 calcium homeostasis modulator 2 -2.70065
ORC1 origin recognition complex, subunit 1 -2.68478
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -2.66482
STEAP1 six transmembrane epithelial antigen of the prostate 1 -2.59892
PMPCB peptidase (mitochondrial processing) beta -2.58505
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -2.56598
IL27RA interleukin 27 receptor, alpha -2.55602
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -2.55562
COMMD4 COMM domain containing 4 -2.54305
RLN1 relaxin 1 -2.53066
ADCY3 adenylate cyclase 3 -2.48213
ADD3 adducin 3 (gamma) -2.47605
C1RL complement component 1, r subcomponent-like -2.47475
HSDL2 hydroxysteroid dehydrogenase like 2 -2.47162
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -2.46948
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.4443
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -2.43419
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -2.42993
GLS glutaminase -2.42895
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.42407
ACE2 angiotensin I converting enzyme 2 -2.42245
CENPN centromere protein N -2.40003
PFDN1 prefoldin subunit 1 -2.3961
PRMT3 protein arginine methyltransferase 3 -2.3891
FSCN1 fascin actin-bundling protein 1 -2.38557
CD163 CD163 molecule -2.38168
PAQR3 progestin and adipoQ receptor family member III -2.3713
YBX3 Y box binding protein 3 -2.36632
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.35332
ARHGAP24 Rho GTPase activating protein 24 -2.34954
PRKD3 protein kinase D3 -2.33484
ZBTB20 zinc finger and BTB domain containing 20 -2.30795
IRS2 insulin receptor substrate 2 -2.29407
PROS1 protein S (alpha) -2.29269
IL2 interleukin 2 -2.29264
BIN1 bridging integrator 1 -2.29211
LYN LYN proto-oncogene, Src family tyrosine kinase -2.29134
EDDM3A epididymal protein 3A -2.28916
TP53 tumor protein p53 -2.27889
RFX3 regulatory factor X, 3 (influences HLA class II expression) -2.24818
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.24259
SKAP2 src kinase associated phosphoprotein 2 -2.24224
PPT2 palmitoyl-protein thioesterase 2 -2.23797
GDF11 growth differentiation factor 11 -2.23287
DIAPH2-AS1 DIAPH2 antisense RNA 1 -2.20434
HIST1H4B histone cluster 1, H4b -2.20084
PELI1 pellino E3 ubiquitin protein ligase 1 -2.19562
BTBD1 BTB (POZ) domain containing 1 -2.19265
CCDC69 coiled-coil domain containing 69 -2.18309
COIL coilin -2.1796
TTF2 transcription termination factor, RNA polymerase II -2.17489
SNX10 sorting nexin 10 -2.16518
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -2.16476
ADGRE5 adhesion G protein-coupled receptor E5 -2.16103
TEX10 testis expressed 10 -2.15626
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) -2.15176
HCRTR2 hypocretin (orexin) receptor 2 -2.14766
OSBPL9 oxysterol binding protein-like 9 -2.14606
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -2.12479
EMP1 epithelial membrane protein 1 -2.12432
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.11369
PTPRB protein tyrosine phosphatase, receptor type, B -2.10337
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.09743
TRDN triadin -2.09511
ANXA11 annexin A11 -2.06382
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -2.06236
IFT57 intraflagellar transport 57 -2.0581
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -2.05048
NLRX1 NLR family member X1 -2.02048
PSMC3IP PSMC3 interacting protein -2.0193
SRI sorcin -2.01668
CREB5 cAMP responsive element binding protein 5 -1.99727
STAT5B signal transducer and activator of transcription 5B -1.9928
ELF5 E74-like factor 5 (ets domain transcription factor) -1.9886
NCAPG2 non-SMC condensin II complex, subunit G2 -1.98391
ZNHIT1 zinc finger, HIT-type containing 1 -1.98257
GPR171 G protein-coupled receptor 171 -1.97906
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -1.97569
PRPF4 pre-mRNA processing factor 4 -1.97339
LINC00869 long intergenic non-protein coding RNA 869 -1.97222
PLAG1 pleiomorphic adenoma gene 1 -1.9688
MMRN1 multimerin 1 -1.96751
CCDC28A coiled-coil domain containing 28A -1.96511
WDR61 WD repeat domain 61 -1.96445
PGAP1 post-GPI attachment to proteins 1 -1.96202
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.95776
FKTN fukutin -1.95287
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) -1.94864
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -1.94416
BRCA1 breast cancer 1, early onset -1.93768
HOXB6 homeobox B6 -1.93354
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -1.93122
TNNI3 troponin I type 3 (cardiac) -1.92343
EXTL3 exostosin-like glycosyltransferase 3 -1.92239
FOXO4 forkhead box O4 -1.92137
CR2 complement component (3d/Epstein Barr virus) receptor 2 -1.9179
IKZF4 IKAROS family zinc finger 4 (Eos) -1.9144
MRPL16 mitochondrial ribosomal protein L16 -1.91036
TCHH trichohyalin -1.89666
ATP11B ATPase, class VI, type 11B -1.8938
TSPAN12 tetraspanin 12 -1.89122
PRIM2 primase, DNA, polypeptide 2 (58kDa) -1.89056
BPGM 2,3-bisphosphoglycerate mutase -1.88931
PTGDR prostaglandin D2 receptor (DP) -1.88628
TPP2 tripeptidyl peptidase II -1.88287
ZNF394 zinc finger protein 394 -1.87647
MAG myelin associated glycoprotein -1.87408
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -1.87251
DGKA diacylglycerol kinase, alpha 80kDa -1.85795
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -1.85455
CD40 CD40 molecule, TNF receptor superfamily member 5 -1.85116
CAMTA1 calmodulin binding transcription activator 1 -1.84302
HPSE heparanase -1.83509
IL24 interleukin 24 -1.82677
PDGFRL platelet-derived growth factor receptor-like -1.82669
NXN nucleoredoxin -1.81115
TUBA1A tubulin, alpha 1a -1.8071
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -1.80585
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -1.8025
HAS1 hyaluronan synthase 1 -1.7983
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -1.79656
ZNF639 zinc finger protein 639 -1.79413
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -1.79371
DPY19L1 dpy-19-like 1 (C. elegans) -1.78238
MYO5A myosin VA (heavy chain 12, myoxin) -1.77974
TEX11 testis expressed 11 -1.77481
RAB32 RAB32, member RAS oncogene family -1.76878
PML promyelocytic leukemia -1.7608
IL5RA interleukin 5 receptor, alpha -1.76078
ASXL2 additional sex combs like transcriptional regulator 2 -1.75969
GABARAPL1 GABA(A) receptor-associated protein like 1 -1.74773
EXOSC5 exosome component 5 -1.74671
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) -1.74624
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -1.74376
TUBA1B tubulin, alpha 1b -1.74355
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -1.74319
CXCR5 chemokine (C-X-C motif) receptor 5 -1.73671
CLIP2 CAP-GLY domain containing linker protein 2 -1.73589
EIF3F eukaryotic translation initiation factor 3, subunit F -1.73385
S100A12 S100 calcium binding protein A12 -1.73301
AKR1C3 aldo-keto reductase family 1, member C3 -1.73128
FBXO40 F-box protein 40 -1.72952
TMEM38B transmembrane protein 38B -1.72664
PPP4R4 protein phosphatase 4, regulatory subunit 4 -1.72628
STRA6 stimulated by retinoic acid 6 -1.71623
PPARA peroxisome proliferator-activated receptor alpha -1.71067
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -1.7079
HOXB7 homeobox B7 -1.70593
COG5 component of oligomeric golgi complex 5 -1.70584
TDRD1 tudor domain containing 1 -1.70243
CCNE1 cyclin E1 -1.70102
ITM2C integral membrane protein 2C -1.70025
LOC644450 uncharacterized LOC644450 -1.69739
MFGE8 milk fat globule-EGF factor 8 protein -1.69649
ARL2 ADP-ribosylation factor-like 2 -1.69438
NT5M 5',3'-nucleotidase, mitochondrial -1.69111
TEF thyrotrophic embryonic factor -1.68291
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -1.68134
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene -1.67838
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 -1.67408
TMEM8A transmembrane protein 8A -1.67381
UNC13A unc-13 homolog A (C. elegans) -1.67248
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -1.67095
SYTL2 synaptotagmin-like 2 -1.66853
MATN2 matrilin 2 -1.66387
MED28 mediator complex subunit 28 -1.66301
RPA1 replication protein A1, 70kDa -1.65999
WRN Werner syndrome, RecQ helicase-like -1.65857
CHN1 chimerin 1 -1.6575
EMG1 EMG1 N1-specific pseudouridine methyltransferase -1.65557
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 -1.65474
EDC3 enhancer of mRNA decapping 3 -1.65192
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -1.6497
STAR steroidogenic acute regulatory protein -1.64679
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 -1.64644
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -1.64628
PHLDA1 pleckstrin homology-like domain, family A, member 1 -1.6443
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.63769
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -1.63462
GDAP1 ganglioside induced differentiation associated protein 1 -1.62094
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -1.6178
BICD2 bicaudal D homolog 2 (Drosophila) -1.6156
FYN FYN proto-oncogene, Src family tyrosine kinase -1.61488
WDR73 WD repeat domain 73 -1.61209
SRPK2 SRSF protein kinase 2 -1.61107
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.61082
CIB2 calcium and integrin binding family member 2 -1.60705
RPL27 ribosomal protein L27 -1.60654
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -1.606
GPNMB glycoprotein (transmembrane) nmb -1.60404
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -1.60363
ADAM12 ADAM metallopeptidase domain 12 -1.60042
PSIP1 PC4 and SFRS1 interacting protein 1 -1.59442
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 -1.5905
TIMP2 TIMP metallopeptidase inhibitor 2 -1.58881
DOCK10 dedicator of cytokinesis 10 -1.58451
CBR1 carbonyl reductase 1 -1.58378
PPAP2A phosphatidic acid phosphatase type 2A -1.58222
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -1.58045
MX1 MX dynamin-like GTPase 1 -1.57993
SACS sacsin molecular chaperone -1.57153
ZNF37BP zinc finger protein 37B, pseudogene -1.56985
ZNF219 zinc finger protein 219 -1.56562
PRRX1 paired related homeobox 1 -1.56508
ECH1 enoyl CoA hydratase 1, peroxisomal -1.56204
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -1.55898
MAGEB2 melanoma antigen family B2 -1.55745
AGXT alanine-glyoxylate aminotransferase -1.55608
ICAM5 intercellular adhesion molecule 5, telencephalin -1.55521
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -1.54769
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -1.54468
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.54128
JAM3 junctional adhesion molecule 3 -1.53709
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -1.53035
TRHDE thyrotropin-releasing hormone degrading enzyme -1.5281
FBXO17 F-box protein 17 -1.52721
WIPF2 WAS/WASL interacting protein family, member 2 -1.52521
LIMS1 LIM and senescent cell antigen-like domains 1 -1.5236
TBC1D2B TBC1 domain family, member 2B -1.52271
RHOBTB3 Rho-related BTB domain containing 3 -1.52123
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -1.52117
ARSE arylsulfatase E (chondrodysplasia punctata 1) -1.52
OR12D3 olfactory receptor, family 12, subfamily D, member 3 -1.51439
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -1.51364
FOXF1 forkhead box F1 -1.5104
EXOSC9 exosome component 9 -1.5099
GPATCH8 G patch domain containing 8 -1.50916
ONECUT1 one cut homeobox 1 -1.50885
HOXA5 homeobox A5 -1.50715
OR1G1 olfactory receptor, family 1, subfamily G, member 1 -1.50518
PRCP prolylcarboxypeptidase (angiotensinase C) -1.50392
GYPA glycophorin A (MNS blood group) -1.50276
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -1.50233
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.50066
DPYS dihydropyrimidinase -1.49753
UPP1 uridine phosphorylase 1 -1.4973
EFHC2 EF-hand domain (C-terminal) containing 2 -1.49191
EXOG endo/exonuclease (5'-3'), endonuclease G-like -1.49101
NOX1 NADPH oxidase 1 -1.48927
LIAS lipoic acid synthetase -1.48705
PAX1 paired box 1 -1.48638
GINS2 GINS complex subunit 2 (Psf2 homolog) -1.4838
ADPGK ADP-dependent glucokinase -1.48178
SGK1 serum/glucocorticoid regulated kinase 1 -1.47493
NNT nicotinamide nucleotide transhydrogenase -1.47419
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -1.4735
IGFBP7 insulin-like growth factor binding protein 7 -1.4716
LEPROTL1 leptin receptor overlapping transcript-like 1 -1.47095
BTN3A2 butyrophilin, subfamily 3, member A2 -1.46928
RPAIN RPA interacting protein -1.46921
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) -1.467
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.46619
PDE8A phosphodiesterase 8A -1.46509
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 -1.46372
ADA adenosine deaminase -1.46333
CDON cell adhesion associated, oncogene regulated -1.46166
IL23A interleukin 23, alpha subunit p19 -1.46148
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -1.46144
CDK18 cyclin-dependent kinase 18 -1.45802
HABP4 hyaluronan binding protein 4 -1.45577
PHLDA3 pleckstrin homology-like domain, family A, member 3 -1.45483
TMEM35 transmembrane protein 35 -1.44613
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -1.44601
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -1.44597
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -1.44555
LDHB lactate dehydrogenase B -1.44525
TEK TEK tyrosine kinase, endothelial -1.44219
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -1.44153
IL10RA interleukin 10 receptor, alpha -1.44022
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 -1.43458
CLIC4 chloride intracellular channel 4 -1.43258
SUSD5 sushi domain containing 5 -1.4314
ALPI alkaline phosphatase, intestinal -1.42896
ZNRF4 zinc and ring finger 4 -1.42838
LRRC49 leucine rich repeat containing 49 -1.42521
MDH1 malate dehydrogenase 1, NAD (soluble) -1.42165
GJA1 gap junction protein, alpha 1, 43kDa -1.42164
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -1.41856
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -1.41612
TSPAN6 tetraspanin 6 -1.41607
POU3F3 POU class 3 homeobox 3 -1.41559