MDA-MB-453 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
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Genes

62 genes with high or low copy number in MDA-MB-453 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
LUZP2 leucine zipper protein 2 4.51153
PYGO1 pygopus family PHD finger 1 4.51153
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 4.51153
XRN2 5'-3' exoribonuclease 2 2.76305
USH1G Usher syndrome 1G (autosomal recessive) 2.64759
CDR2L cerebellar degeneration-related protein 2-like 2.64759
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 2.64759
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 2.64759
FADS6 fatty acid desaturase 6 2.64759
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 2.64759
KCTD2 potassium channel tetramerization domain containing 2 2.64759
COX11 COX11 cytochrome c oxidase copper chaperone 2.64759
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 2.64759
HID1 HID1 domain containing 2.64759
OTOP2 otopetrin 2 2.64759
OTOP3 otopetrin 3 2.64759
ICT1 immature colon carcinoma transcript 1 2.64759
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 2.64759
NT5C 5', 3'-nucleotidase, cytosolic 2.59653
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.59653
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 2.59653
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.59653
C17ORF58 chromosome 17 open reading frame 58 2.59653
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 2.59653
SNORA38B small nucleolar RNA, H/ACA box 38B 2.59653
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 2.59653
STXBP4 syntaxin binding protein 4 2.59653
SUMO2 small ubiquitin-like modifier 2 2.59653
ARMC7 armadillo repeat containing 7 2.59653
MRPS7 mitochondrial ribosomal protein S7 2.59653
NUP85 nucleoporin 85kDa 2.59653
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2.59653
NOL11 nucleolar protein 11 2.59653
BPTF bromodomain PHD finger transcription factor 2.59653
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 2.59653
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 2.59653
LOC100287042 uncharacterized LOC100287042 2.59653
HN1 hematological and neurological expressed 1 2.59653
MIF4GD MIF4G domain containing 2.59653
HELZ helicase with zinc finger 2.49065
PRKCA protein kinase C, alpha 2.49065
MIR634 microRNA 634 2.49065
CEP112 centrosomal protein 112kDa 2.44392
BRIP1 BRCA1 interacting protein C-terminal helicase 1 2.35236
PRTG protogenin 2.15316
TUSC1 tumor suppressor candidate 1 2.12573
MIR635 microRNA 635 2.10992
LOC440461 Rho GTPase activating protein 27 pseudogene 2.10992
ARSG arylsulfatase G 2.10992
LINC00674 long intergenic non-protein coding RNA 674 2.10992
SLC16A6 solute carrier family 16, member 6 2.10992
TOM1L1 target of myb1 (chicken)-like 1 2.10992
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.10992
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.10992
FAM20A family with sequence similarity 20, member A 2.10992
AMZ2 archaelysin family metallopeptidase 2 2.10992
AXIN2 axin 2 2.09431

low copy number

Symbol Name Standardized Value
RBMXL3 RNA binding motif protein, X-linked-like 3 -3.83684
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2 -3.61078
SNORA35 small nucleolar RNA, H/ACA box 35 -3.12964
OR52N5 olfactory receptor, family 52, subfamily N, member 5 -2.84224
OR52N1 olfactory receptor, family 52, subfamily N, member 1 -2.73524