MDA-MB-436 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

83 genes mutated in the MDA-MB-436 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKRD26 ankyrin repeat domain 26
ASPH aspartate beta-hydroxylase
BIRC6 baculoviral IAP repeat containing 6
C10ORF88 chromosome 10 open reading frame 88
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPE centromere protein E, 312kDa
CLUH clustered mitochondria (cluA/CLU1) homolog
COL6A2 collagen, type VI, alpha 2
DCAF5 DDB1 and CUL4 associated factor 5
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGKZ diacylglycerol kinase, zeta
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNA2 DNA replication helicase/nuclease 2
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK4 docking protein 4
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ERLIN2 ER lipid raft associated 2
EXD2 exonuclease 3'-5' domain containing 2
EXOSC10 exosome component 10
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM162A family with sequence similarity 162, member A
FAM184A family with sequence similarity 184, member A
FANCI Fanconi anemia, complementation group I
FBN2 fibrillin 2
FLNA filamin A, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GMPR2 guanosine monophosphate reductase 2
HACD1 3-hydroxyacyl-CoA dehydratase 1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HECA headcase homolog (Drosophila)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
ITGA6 integrin, alpha 6
KANK2 KN motif and ankyrin repeat domains 2
KIAA1324L KIAA1324-like
KIF20B kinesin family member 20B
LPAR3 lysophosphatidic acid receptor 3
MAGEF1 melanoma antigen family F1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MCM6 minichromosome maintenance complex component 6
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MLH3 mutL homolog 3
MRC2 mannose receptor, C type 2
MRPS16 mitochondrial ribosomal protein S16
NAF1 nuclear assembly factor 1 ribonucleoprotein
NAV2 neuron navigator 2
NUP133 nucleoporin 133kDa
PGP phosphoglycolate phosphatase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PINK1 PTEN induced putative kinase 1
PLA2G16 phospholipase A2, group XVI
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTK2B protein tyrosine kinase 2 beta
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RHOC ras homolog family member C
RMI2 RecQ mediated genome instability 2
SCAF1 SR-related CTD-associated factor 1
SEC23IP SEC23 interacting protein
SEC31A SEC31 homolog A (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOD1 superoxide dismutase 1, soluble
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TMEM104 transmembrane protein 104
TMEM132D transmembrane protein 132D
TMEM55B transmembrane protein 55B
TRAPPC5 trafficking protein particle complex 5
TWIST1 twist family bHLH transcription factor 1
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBOX5 U-box domain containing 5
URI1 URI1, prefoldin-like chaperone
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
UVSSA UV-stimulated scaffold protein A
VSIG10L V-set and immunoglobulin domain containing 10 like
ZFAND1 zinc finger, AN1-type domain 1
ZNF2 zinc finger protein 2
ZNF8 zinc finger protein 8