|Category||structural or functional annotations|
|Description||An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. (Gene Ontology, GO_0000165)|
|Downloads & Tools|
2 proteins participating in the MAP kinase cascade pathway from the HumanCyc Pathways dataset.