Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-11A-11R-A22L-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Liver hepatocellular carcinoma_LIHC (The Cancer Genome Atlas)
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Genes

365 genes with high or low expression in Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-11A-11R-A22L-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADAT aminoadipate aminotransferase
ABAT 4-aminobutyrate aminotransferase
ACAA1 acetyl-CoA acyltransferase 1
ACAA2 acetyl-CoA acyltransferase 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADGRG7 adhesion G protein-coupled receptor G7
ADM adrenomedullin
ADRA1A adrenoceptor alpha 1A
ADRB2 adrenoceptor beta 2, surface
AFM afamin
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AKIRIN1 akirin 1
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANGPTL6 angiopoietin-like 6
APOL1 apolipoprotein L, 1
AQP3 aquaporin 3 (Gill blood group)
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ARL4D ADP-ribosylation factor-like 4D
ARRDC3 arrestin domain containing 3
ARSD arylsulfatase D
ASPG asparaginase
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATG2A autophagy related 2A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCO2 beta-carotene oxygenase 2
BLNK B-cell linker
C16ORF72 chromosome 16 open reading frame 72
C1RL complement component 1, r subcomponent-like
C21ORF33 chromosome 21 open reading frame 33
C2ORF73 chromosome 2 open reading frame 73
C5ORF52 chromosome 5 open reading frame 52
C6 complement component 6
C8A complement component 8, alpha polypeptide
C8ORF4 chromosome 8 open reading frame 4
C9ORF72 chromosome 9 open reading frame 72
CA5A carbonic anhydrase VA, mitochondrial
CAT catalase
CBS cystathionine-beta-synthase
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD14 CD14 molecule
CD81 CD81 molecule
CDC37L1 cell division cycle 37-like 1
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDO1 cysteine dioxygenase type 1
CHIC2 cysteine-rich hydrophobic domain 2
CIDEB cell death-inducing DFFA-like effector b
CIRBP-AS1 CIRBP antisense RNA 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
COL6A6 collagen, type VI, alpha 6
CPED1 cadherin-like and PC-esterase domain containing 1
CPN2 carboxypeptidase N, polypeptide 2
CTPS1 CTP synthase 1
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DENND4A DENN/MADD domain containing 4A
DHODH dihydroorotate dehydrogenase (quinone)
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DNMBP dynamin binding protein
DPF3 D4, zinc and double PHD fingers, family 3
DTX1 deltex 1, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
DUSP14 dual specificity phosphatase 14
DUSP16 dual specificity phosphatase 16
DUSP6 dual specificity phosphatase 6
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
EIF5 eukaryotic translation initiation factor 5
ELL elongation factor RNA polymerase II
ELL2 elongation factor, RNA polymerase II, 2
EPAS1 endothelial PAS domain protein 1
EPHA2 EPH receptor A2
ERLIN1 ER lipid raft associated 1
ERRFI1 ERBB receptor feedback inhibitor 1
ETFDH electron-transferring-flavoprotein dehydrogenase
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EYA2 EYA transcriptional coactivator and phosphatase 2
F12 coagulation factor XII (Hageman factor)
FAM102A family with sequence similarity 102, member A
FAM110C family with sequence similarity 110, member C
FAM134B family with sequence similarity 134, member B
FAM198A family with sequence similarity 198, member A
FAM46A family with sequence similarity 46, member A
FAM46C family with sequence similarity 46, member C
FAXDC2 fatty acid hydroxylase domain containing 2
FBP1 fructose-1,6-bisphosphatase 1
FCAR Fc fragment of IgA receptor
FHL2 four and a half LIM domains 2
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FPR2 formyl peptide receptor 2
FRMD4B FERM domain containing 4B
FTCD formimidoyltransferase cyclodeaminase
GABARAPL1 GABA(A) receptor-associated protein like 1
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GAN gigaxonin
GAREM GRB2 associated, regulator of MAPK1
GATA4 GATA binding protein 4
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GC group-specific component (vitamin D binding protein)
GCDH glutaryl-CoA dehydrogenase
GDPGP1 GDP-D-glucose phosphorylase 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GHR growth hormone receptor
GLT1D1 glycosyltransferase 1 domain containing 1
GPHN gephyrin
GPR146 G protein-coupled receptor 146
GPR180 G protein-coupled receptor 180
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GRAMD3 GRAM domain containing 3
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSTZ1 glutathione S-transferase zeta 1
GYS2 glycogen synthase 2 (liver)
HAMP hepcidin antimicrobial peptide
HAO2 hydroxyacid oxidase 2 (long chain)
HELB helicase (DNA) B
HHEX hematopoietically expressed homeobox
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HP haptoglobin
HPX hemopexin
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO2 indoleamine 2,3-dioxygenase 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL1RAP interleukin 1 receptor accessory protein
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
IL4R interleukin 4 receptor
IRF2BPL interferon regulatory factor 2 binding protein-like
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPKC inositol-trisphosphate 3-kinase C
IYD iodotyrosine deiodinase
JUN jun proto-oncogene
JUND jun D proto-oncogene
KALRN kalirin, RhoGEF kinase
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM6B lysine (K)-specific demethylase 6B
KDSR 3-ketodihydrosphingosine reductase
KIAA0040 KIAA0040
KLF6 Kruppel-like factor 6
KLHL15 kelch-like family member 15
KLHL25 kelch-like family member 25
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LCAT lecithin-cholesterol acyltransferase
LDLR low density lipoprotein receptor
LIPN lipase, family member N
LNX2 ligand of numb-protein X 2
LOC647859 occludin pseudogene
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene
LONP2 lon peptidase 2, peroxisomal
LONRF1 LON peptidase N-terminal domain and ring finger 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPA lipoprotein, Lp(a)
LPIN2 lipin 2
LRRC19 leucine rich repeat containing 19
LTBP3 latent transforming growth factor beta binding protein 3
LURAP1L leucine rich adaptor protein 1-like
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K3 mitogen-activated protein kinase kinase 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MAT1A methionine adenosyltransferase I, alpha
MBIP MAP3K12 binding inhibitory protein 1
MBNL2 muscleblind-like splicing regulator 2
MCL1 myeloid cell leukemia 1
MT1A metallothionein 1A
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO1B myosin IB
N4BP2L1 NEDD4 binding protein 2-like 1
NAMPT nicotinamide phosphoribosyltransferase
NDEL1 nudE neurodevelopment protein 1-like 1
NDRG2 NDRG family member 2
NFIL3 nuclear factor, interleukin 3 regulated
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NNMT nicotinamide N-methyltransferase
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRBF2 nuclear receptor binding factor 2
NRG1 neuregulin 1
NSUN6 NOP2/Sun domain family, member 6
ODF3L1 outer dense fiber of sperm tails 3-like 1
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OTUD4 OTU deubiquitinase 4
PADI4 peptidyl arginine deiminase, type IV
PALM2 paralemmin 2
PANK1 pantothenate kinase 1
PBLD phenazine biosynthesis-like protein domain containing
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE7B phosphodiesterase 7B
PER2 period circadian clock 2
PGM1 phosphoglucomutase 1
PHF13 PHD finger protein 13
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PITPNB phosphatidylinositol transfer protein, beta
PLG plasminogen
PLIN1 perilipin 1
PLK3 polo-like kinase 3
PLSCR4 phospholipid scramblase 4
PNP purine nucleoside phosphorylase
PNPLA8 patatin-like phospholipase domain containing 8
PNRC1 proline-rich nuclear receptor coactivator 1
PON3 paraoxonase 3
POR P450 (cytochrome) oxidoreductase
PPAP2B phosphatidic acid phosphatase type 2B
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PROK2 prokineticin 2
PRR18 proline rich 18
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PXDC1 PX domain containing 1
RAB30 RAB30, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAG2 recombination activating gene 2
RALGDS ral guanine nucleotide dissociation stimulator
RANBP3L RAN binding protein 3-like
RASGEF1B RasGEF domain family, member 1B
RBM47 RNA binding motif protein 47
RBM7 RNA binding motif protein 7
RCL1 RNA terminal phosphate cyclase-like 1
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RGCC regulator of cell cycle
RGS7 regulator of G-protein signaling 7
RHOB ras homolog family member B
RIPK4 receptor-interacting serine-threonine kinase 4
RND3 Rho family GTPase 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF152 ring finger protein 152
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
S100A12 S100 calcium binding protein A12
SARDH sarcosine dehydrogenase
SDC4 syndecan 4
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERTAD1 SERTA domain containing 1
SGMS2 sphingomyelin synthase 2
SHB Src homology 2 domain containing adaptor protein B
SIK2 salt-inducible kinase 2
SIK3 SIK family kinase 3
SIRPB1 signal-regulatory protein beta 1
SLC16A12 solute carrier family 16, member 12
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC25A18 solute carrier family 25 (glutamate carrier), member 18
SLC25A47 solute carrier family 25, member 47
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35G5 solute carrier family 35, member G5
SLC38A2 solute carrier family 38, member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC51A solute carrier family 51, alpha subunit
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLITRK3 SLIT and NTRK-like family, member 3
SNORA71A small nucleolar RNA, H/ACA box 71A
SNORA71D small nucleolar RNA, H/ACA box 71D
SNORD115-13 small nucleolar RNA, C/D box 115-13
SNX33 sorting nexin 33
SNX9 sorting nexin 9
SOCS2 suppressor of cytokine signaling 2
SOWAHC sosondowah ankyrin repeat domain family member C
SOX6 SRY (sex determining region Y)-box 6
SPINK6 serine peptidase inhibitor, Kazal type 6
SPRY2 sprouty homolog 2 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSBP3 single stranded DNA binding protein 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK40 serine/threonine kinase 40
STOM stomatin
STRN3 striatin, calmodulin binding protein 3
SYT9 synaptotagmin IX
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TAT tyrosine aminotransferase
TBC1D15 TBC1 domain family, member 15
TDO2 tryptophan 2,3-dioxygenase
TF transferrin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TJP2 tight junction protein 2
TMEM154 transmembrane protein 154
TMEM263 transmembrane protein 263
TMEM82 transmembrane protein 82
TMPRSS2 transmembrane protease, serine 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TPST1 tyrosylprotein sulfotransferase 1
TRAM2 translocation associated membrane protein 2
TRIB1 tribbles pseudokinase 1
TRIM35 tripartite motif containing 35
TSC22D2 TSC22 domain family, member 2
TSLP thymic stromal lymphopoietin
TTC36 tetratricopeptide repeat domain 36
TTLL11 tubulin tyrosine ligase-like family member 11
TTR transthyretin
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBALD1 UBA-like domain containing 1
UBAP1 ubiquitin associated protein 1
UBC ubiquitin C
UROC1 urocanate hydratase 1
USP12 ubiquitin specific peptidase 12
USP38 ubiquitin specific peptidase 38
USP47 ubiquitin specific peptidase 47
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VNN1 vanin 1
WEE1 WEE1 G2 checkpoint kinase
WNT11 wingless-type MMTV integration site family, member 11
YPEL2 yippee-like 2 (Drosophila)
ZBTB21 zinc finger and BTB domain containing 21
ZBTB43 zinc finger and BTB domain containing 43
ZBTB7A zinc finger and BTB domain containing 7A
ZC2HC1C zinc finger, C2HC-type containing 1C
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF367 zinc finger protein 367
ZNF800 zinc finger protein 800

low expression

Symbol Name
TCHP trichoplein, keratin filament binding