Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-11A-11R-A22L-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Liver hepatocellular carcinoma_LIHC (The Cancer Genome Atlas)
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Genes

422 genes with high or low expression in Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-11A-11R-A22L-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACTRT3 actin-related protein T3
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADM adrenomedullin
ADRA2B adrenoceptor alpha 2B
AGTR1 angiotensin II receptor, type 1
AGXT alanine-glyoxylate aminotransferase
AKIRIN1 akirin 1
ALAS1 5'-aminolevulinate synthase 1
AMDHD1 amidohydrolase domain containing 1
AMHR2 anti-Mullerian hormone receptor, type II
ANGPTL4 angiopoietin-like 4
ANGPTL6 angiopoietin-like 6
ANKRD55 ankyrin repeat domain 55
ANTXRL anthrax toxin receptor-like
ANXA10 annexin A10
AOX2P aldehyde oxidase 2 pseudogene
APOF apolipoprotein F
ASPG asparaginase
ASS1 argininosuccinate synthase 1
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
AURKC aurora kinase C
AXL AXL receptor tyrosine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL3 B-cell CLL/lymphoma 3
BEND2 BEN domain containing 2
BHLHE40 basic helix-loop-helix family, member e40
BMPER BMP binding endothelial regulator
BMX BMX non-receptor tyrosine kinase
C10ORF107 chromosome 10 open reading frame 107
C14ORF180 chromosome 14 open reading frame 180
C17ORF102 chromosome 17 open reading frame 102
C19ORF26 chromosome 19 open reading frame 26
C1ORF162 chromosome 1 open reading frame 162
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
C2ORF40 chromosome 2 open reading frame 40
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCBE1 collagen and calcium binding EGF domains 1
CCDC116 coiled-coil domain containing 116
CCDC184 coiled-coil domain containing 184
CCDC3 coiled-coil domain containing 3
CCL14 chemokine (C-C motif) ligand 14
CCL3 chemokine (C-C motif) ligand 3
CCNH cyclin H
CCR1 chemokine (C-C motif) receptor 1
CD14 CD14 molecule
CD163 CD163 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD300A CD300a molecule
CD300C CD300c molecule
CD300LG CD300 molecule-like family member g
CD4 CD4 molecule
CD5L CD5 molecule-like
CD68 CD68 molecule
CD83 CD83 molecule
CDH20 cadherin 20, type 2
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CETP cholesteryl ester transfer protein, plasma
CFAP58 cilia and flagella associated protein 58
CFP complement factor properdin
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CISH cytokine inducible SH2-containing protein
CLEC10A C-type lectin domain family 10, member A
CLEC12A C-type lectin domain family 12, member A
CLEC3B C-type lectin domain family 3, member B
CLEC4G C-type lectin domain family 4, member G
CLEC4M C-type lectin domain family 4, member M
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNGA1 cyclic nucleotide gated channel alpha 1
CNN2 calponin 2
CNPY3 canopy FGF signaling regulator 3
COLEC10 collectin sub-family member 10 (C-type lectin)
COLEC11 collectin sub-family member 11
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPXM2 carboxypeptidase X (M14 family), member 2
CREM cAMP responsive element modulator
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRYBA1 crystallin, beta A1
CSF1R colony stimulating factor 1 receptor
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CSRNP1 cysteine-serine-rich nuclear protein 1
CTSB cathepsin B
CTSL cathepsin L
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXORF58 chromosome X open reading frame 58
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DCN decorin
DDT D-dopachrome tautomerase
DDTL D-dopachrome tautomerase-like
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DENND2A DENN/MADD domain containing 2A
DHODH dihydroorotate dehydrogenase (quinone)
DHRS7C dehydrogenase/reductase (SDR family) member 7C
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3OS DIO3 opposite strand/antisense RNA (head to head)
DISC2 disrupted in schizophrenia 2 (non-protein coding)
DLC1 DLC1 Rho GTPase activating protein
DNASE1L3 deoxyribonuclease I-like 3
DPEP2 dipeptidase 2
DUSP16 dual specificity phosphatase 16
EBI3 Epstein-Barr virus induced 3
ECM1 extracellular matrix protein 1
EDN1 endothelin 1
EFCC1 EF-hand and coiled-coil domain containing 1
EGR1 early growth response 1
ELAC1 elaC ribonuclease Z 1
ELL elongation factor RNA polymerase II
ELL2 elongation factor, RNA polymerase II, 2
ENG endoglin
EPAS1 endothelial PAS domain protein 1
ERVFRD-1 endogenous retrovirus group FRD, member 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2 coagulation factor II (thrombin)
FAAH2 fatty acid amide hydrolase 2
FAM101B family with sequence similarity 101, member B
FAM107A family with sequence similarity 107, member A
FAM163B family with sequence similarity 163, member B
FAM177A1 family with sequence similarity 177, member A1
FAM180A family with sequence similarity 180, member A
FAM71A family with sequence similarity 71, member A
FAM74A1 family with sequence similarity 74, member A1
FAM74A4 family with sequence similarity 74, member A4
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FFAR1 free fatty acid receptor 1
FGB fibrinogen beta chain
FGF23 fibroblast growth factor 23
FGG fibrinogen gamma chain
FGL2 fibrinogen-like 2
FNDC4 fibronectin type III domain containing 4
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLH1B folate hydrolase 1B
FOLR2 folate receptor 2 (fetal)
FOXF1 forkhead box F1
FOXO1 forkhead box O1
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FPR3 formyl peptide receptor 3
FXYD6 FXYD domain containing ion transport regulator 6
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GAREM GRB2 associated, regulator of MAPK1
GATA6 GATA binding protein 6
GCDH glutaryl-CoA dehydrogenase
GDF2 growth differentiation factor 2
GDF3 growth differentiation factor 3
GLS2 glutaminase 2 (liver, mitochondrial)
GLT1D1 glycosyltransferase 1 domain containing 1
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GNMT glycine N-methyltransferase
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPM6A glycoprotein M6A
GPR162 G protein-coupled receptor 162
GPR83 G protein-coupled receptor 83
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRK5 G protein-coupled receptor kinase 5
GTF2IRD2P1 GTF2I repeat domain containing 2 pseudogene 1
GZF1 GDNF-inducible zinc finger protein 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAL histidine ammonia-lyase
HAMP hepcidin antimicrobial peptide
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HCRTR1 hypocretin (orexin) receptor 1
HES1 hes family bHLH transcription factor 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL15RA interleukin 15 receptor, alpha
IL1RL1 interleukin 1 receptor-like 1
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INHBB inhibin, beta B
INMT indolethylamine N-methyltransferase
IRF2BPL interferon regulatory factor 2 binding protein-like
IRF8 interferon regulatory factor 8
ISCA1 iron-sulfur cluster assembly 1
ISCA1P1 iron-sulfur cluster assembly 1 pseudogene 1
ITGAD integrin, alpha D
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
JDP2 Jun dimerization protein 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KCNK16 potassium channel, two pore domain subfamily K, member 16
KCTD4 potassium channel tetramerization domain containing 4
KHDC3L KH domain containing 3-like, subcortical maternal complex member
KIF19 kinesin family member 19
KLF10 Kruppel-like factor 10
KLF11 Kruppel-like factor 11
LCE2C late cornified envelope 2C
LCN6 lipocalin 6
LGMN legumain
LIFR leukemia inhibitory factor receptor alpha
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LINC00475 long intergenic non-protein coding RNA 475
LINC00574 long intergenic non-protein coding RNA 574
LOC653786 otoancorin pseudogene
LRG1 leucine-rich alpha-2-glycoprotein 1
LRRC55 leucine rich repeat containing 55
LRRC61 leucine rich repeat containing 61
LRRC70 leucine rich repeat containing 70
LRRC71 leucine rich repeat containing 71
LTBP4 latent transforming growth factor beta binding protein 4
LY86 lymphocyte antigen 86
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAG myelin associated glycoprotein
MAK male germ cell-associated kinase
MAP2K3 mitogen-activated protein kinase kinase 3
MARCO macrophage receptor with collagenous structure
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCL1 myeloid cell leukemia 1
MIDN midnolin
MIP major intrinsic protein of lens fiber
MMRN1 multimerin 1
MOB3C MOB kinase activator 3C
MOG myelin oligodendrocyte glycoprotein
MPEG1 macrophage expressed 1
MPPED1 metallophosphoesterase domain containing 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MS4A7 membrane-spanning 4-domains, subfamily A, member 7
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MT1E metallothionein 1E
MT1X metallothionein 1X
MT2A metallothionein 2A
MYADM myeloid-associated differentiation marker
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCT1 myc target 1
MYD88 myeloid differentiation primary response 88
NAF1 nuclear assembly factor 1 ribonucleoprotein
NAMPT nicotinamide phosphoribosyltransferase
NAP1L5 nucleosome assembly protein 1-like 5
NCOA7 nuclear receptor coactivator 7
NDEL1 nudE neurodevelopment protein 1-like 1
NDRG2 NDRG family member 2
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NFAM1 NFAT activating protein with ITAM motif 1
NFIL3 nuclear factor, interleukin 3 regulated
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NKX3-1 NK3 homeobox 1
NLRP3 NLR family, pyrin domain containing 3
NNMT nicotinamide N-methyltransferase
NOP14 NOP14 nucleolar protein
NPR1 natriuretic peptide receptor 1
NPY1R neuropeptide Y receptor Y1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NSUN6 NOP2/Sun domain family, member 6
NTF3 neurotrophin 3
NUDT9P1 nudix (nucleoside diphosphate linked moiety X)-type motif 9 pseudogene 1
OIT3 oncoprotein induced transcript 3
OR1C1 olfactory receptor, family 1, subfamily C, member 1
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2T8 olfactory receptor, family 2, subfamily T, member 8
OSTF1 osteoclast stimulating factor 1
OTOA otoancorin
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III
PABPN1L poly(A) binding protein, nuclear 1-like (cytoplasmic)
PADI6 peptidyl arginine deiminase, type VI
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDZRN4 PDZ domain containing ring finger 4
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGLYRP2 peptidoglycan recognition protein 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PILRA paired immunoglobin-like type 2 receptor alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PITPNM3 PITPNM family member 3
PLA2G16 phospholipase A2, group XVI
PLA2G5 phospholipase A2, group V
PLIN2 perilipin 2
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PNPLA2 patatin-like phospholipase domain containing 2
PNRC1 proline-rich nuclear receptor coactivator 1
PON1 paraoxonase 1
PON3 paraoxonase 3
POR P450 (cytochrome) oxidoreductase
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRAM1 PML-RARA regulated adaptor molecule 1
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PROX2 prospero homeobox 2
PTGIS prostaglandin I2 (prostacyclin) synthase
PTH1R parathyroid hormone 1 receptor
PVALB parvalbumin
PXMP2 peroxisomal membrane protein 2, 22kDa
R3HCC1 R3H domain and coiled-coil containing 1
RAB20 RAB20, member RAS oncogene family
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RASGEF1B RasGEF domain family, member 1B
RBM7 RNA binding motif protein 7
RBMXL1 RNA binding motif protein, X-linked-like 1
RCL1 RNA terminal phosphate cyclase-like 1
RGN regucalcin
RHOB ras homolog family member B
RILPL2 Rab interacting lysosomal protein-like 2
RNF166 ring finger protein 166
RSPH4A radial spoke head 4 homolog A (Chlamydomonas)
RYBP RING1 and YY1 binding protein
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCIMP SLP adaptor and CSK interacting membrane protein
SDC3 syndecan 3
SDC4 syndecan 4
SDS serine dehydratase
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERTAD1 SERTA domain containing 1
SF1 splicing factor 1
SGK1 serum/glucocorticoid regulated kinase 1
SH2D1B SH2 domain containing 1B
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SIGLEC5 sialic acid binding Ig-like lectin 5
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC36A3 solute carrier family 36, member 3
SLITRK3 SLIT and NTRK-like family, member 3
SMIM12 small integral membrane protein 12
SNORA38B small nucleolar RNA, H/ACA box 38B
SNORA6 small nucleolar RNA, H/ACA box 6
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SPP2 secreted phosphoprotein 2, 24kDa
SPRY2 sprouty homolog 2 (Drosophila)
SRGN serglycin
SRSF3 serine/arginine-rich splicing factor 3
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
STAB1 stabilin 1
STAB2 stabilin 2
STK40 serine/threonine kinase 40
STX11 syntaxin 11
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
TBXA2R thromboxane A2 receptor
TBXAS1 thromboxane A synthase 1 (platelet)
TCEAL7 transcription elongation factor A (SII)-like 7
TDO2 tryptophan 2,3-dioxygenase
TEK TEK tyrosine kinase, endothelial
TEX12 testis expressed 12
THEMIS2 thymocyte selection associated family member 2
THPO thrombopoietin
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TLR4 toll-like receptor 4
TM2D2 TM2 domain containing 2
TMEM132D transmembrane protein 132D
TMEM132E transmembrane protein 132E
TMEM212 transmembrane protein 212
TMEM255B transmembrane protein 255B
TMEM26 transmembrane protein 26
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TOR1A torsin family 1, member A (torsin A)
TPPP2 tubulin polymerization-promoting protein family member 2
TPST1 tyrosylprotein sulfotransferase 1
TPT1 tumor protein, translationally-controlled 1
TRAF3IP2 TRAF3 interacting protein 2
TRIB1 tribbles pseudokinase 1
TSPAN7 tetraspanin 7
TTC36 tetratricopeptide repeat domain 36
TULP2 tubby like protein 2
TUSC1 tumor suppressor candidate 1
UBALD1 UBA-like domain containing 1
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VIPR1 vasoactive intestinal peptide receptor 1
VMO1 vitelline membrane outer layer 1 homolog (chicken)
VSIG4 V-set and immunoglobulin domain containing 4
WDR66 WD repeat domain 66
YAF2 YY1 associated factor 2
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36 ZFP36 ring finger protein
ZFPM2 zinc finger protein, FOG family member 2
ZNF274 zinc finger protein 274
ZNF410 zinc finger protein 410
ZNF487 zinc finger protein 487
ZNF584 zinc finger protein 584
ZNF649 zinc finger protein 649
ZNF878 zinc finger protein 878

low expression

Symbol Name
MEN1 multiple endocrine neoplasia I