Lipoproteins Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. (Experimental Factor Ontology, EFO_0003836)
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Genes

79 genes associated with the trait Lipoproteins in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
PLEK pleckstrin 1.46483
LPA lipoprotein, Lp(a) 1.24011
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.00636
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene 0.950352
WDFY4 WDFY family member 4 0.867795
PLG plasminogen 0.842974
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.813587
GRIK2 glutamate receptor, ionotropic, kainate 2 0.767602
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 0.752445
MCF2 MCF.2 cell line derived transforming sequence 0.713566
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.546042
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.386953
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.368804
RNF43 ring finger protein 43 0.362284
CYP2A7P1 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1 0.340978
PID1 phosphotyrosine interaction domain containing 1 0.32693
C4ORF22 chromosome 4 open reading frame 22 0.313865
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 0.303887
ADD2 adducin 2 (beta) 0.269056
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.256228
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 0.253544
KCTD16 potassium channel tetramerization domain containing 16 0.247047
CSMD1 CUB and Sushi multiple domains 1 0.24565
MACROD2 MACRO domain containing 2 0.243242
PTPRD protein tyrosine phosphatase, receptor type, D 0.234014
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.233382
SLC39A1 solute carrier family 39 (zinc transporter), member 1 0.226675
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.221191
TMEM92 transmembrane protein 92 0.220928
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.219759
SNX29 sorting nexin 29 0.217456
THSD4 thrombospondin, type I, domain containing 4 0.215778
PTK2B protein tyrosine kinase 2 beta 0.211835
DCHS2 dachsous cadherin-related 2 0.195521
IL1RAP interleukin 1 receptor accessory protein 0.194998
CNTN5 contactin 5 0.191817
SLC44A3 solute carrier family 44, member 3 0.190818
YIPF5 Yip1 domain family, member 5 0.189412
GATAD2B GATA zinc finger domain containing 2B 0.182551
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.181815
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.176359
CTNND2 catenin (cadherin-associated protein), delta 2 0.165864
ISM1 isthmin 1, angiogenesis inhibitor 0.163486
NRXN1 neurexin 1 0.155889
ALCAM activated leukocyte cell adhesion molecule 0.155136
CEP128 centrosomal protein 128kDa 0.152913
CXXC5 CXXC finger protein 5 0.151719
ZNF599 zinc finger protein 599 0.150766
ATXN1 ataxin 1 0.146221
ZNF385D zinc finger protein 385D 0.145714
IGF2R insulin-like growth factor 2 receptor 0.145433
CSMD2 CUB and Sushi multiple domains 2 0.121483
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.117158
NOVA2 neuro-oncological ventral antigen 2 0.1118
FHIT fragile histidine triad 0.101136
NME8 NME/NM23 family member 8 0.09861
ANKRD60 ankyrin repeat domain 60 0.095218
GRHL1 grainyhead-like 1 (Drosophila) 0.094126
NFIB nuclear factor I/B 0.091165
KDM4C lysine (K)-specific demethylase 4C 0.090911
BOK BCL2-related ovarian killer 0.090807
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.089978
NAV2 neuron navigator 2 0.08859
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.086727
EPHA8 EPH receptor A8 0.085141
AARS2 alanyl-tRNA synthetase 2, mitochondrial 0.079045
SEPT9 septin 9 0.076128
AGBL1 ATP/GTP binding protein-like 1 0.07505
ARID1B AT rich interactive domain 1B (SWI1-like) 0.072794
TRIM42 tripartite motif containing 42 0.072711
GOLGA5 golgin A5 0.069477
ASXL3 additional sex combs like transcriptional regulator 3 0.069008
GPM6A glycoprotein M6A 0.06878
ZFC3H1 zinc finger, C3H1-type containing 0.068712
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.064321
SDC2 syndecan 2 0.061813
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.059736
ENDOD1 endonuclease domain containing 1 0.059574
NTM neurotrimin 0.059356