Leptin signaling pathway(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP2034_r80016
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Genes

61 proteins participating in the Leptin signaling pathway(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAX BCL2-associated X protein
BCL2L1 BCL2-like 1
CCND1 cyclin D1
CDC42 cell division cycle 42
CFL2 cofilin 2 (muscle)
CHUK conserved helix-loop-helix ubiquitous kinase
CISH cytokine inducible SH2-containing protein
CREB1 cAMP responsive element binding protein 1
ELK1 ELK1, member of ETS oncogene family
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
FOXO1 forkhead box O1
FYN FYN proto-oncogene, Src family tyrosine kinase
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IRS1 insulin receptor substrate 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KPNA4 karyopherin alpha 4 (importin alpha 3)
LEP leptin
LEPR leptin receptor
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCOA1 nuclear receptor coactivator 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG1 phospholipase C, gamma 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SH2B1 SH2B adaptor protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS7 suppressor of cytokine signaling 7
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B