Ivermectin Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice. (Chemical Entities of Biological Interest Ontology, CHEBI_6078)
External Link http://www.hmdb.ca/metabolites/HMDB14740
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Genes

7 interacting proteins for the Ivermectin metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GLRA3 glycine receptor, alpha 3