Iron Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=D007501
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Genes

134 genes/proteins interacting with the chemical Iron from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACBD3 acyl-CoA binding domain containing 3
ACO1 aconitase 1, soluble
ACO2 aconitase 2, mitochondrial
AHSP alpha hemoglobin stabilizing protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARNT aryl hydrocarbon receptor nuclear translocator
ATM ATM serine/threonine kinase
ATP7B ATPase, Cu++ transporting, beta polypeptide
B2M beta-2-microglobulin
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BMP6 bone morphogenetic protein 6
CALR calreticulin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCND1 cyclin D1
CD14 CD14 molecule
CDO1 cysteine dioxygenase type 1
CHUK conserved helix-loop-helix ubiquitous kinase
CP ceruloplasmin (ferroxidase)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CYBRD1 cytochrome b reductase 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
EDN1 endothelin 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EPAS1 endothelial PAS domain protein 1
EXOC6 exocyst complex component 6
F2 coagulation factor II (thrombin)
FECH ferrochelatase
FEN1 flap structure-specific endonuclease 1
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
FTMT ferritin mitochondrial
FXN frataxin
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GCLC glutamate-cysteine ligase, catalytic subunit
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
GSTA1 glutathione S-transferase alpha 1
GSTA4 glutathione S-transferase alpha 4
GSTM1 glutathione S-transferase mu 1
HAMP hepcidin antimicrobial peptide
HBA1 hemoglobin, alpha 1
HDAC8 histone deacetylase 8
HEPH hephaestin
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST3H3 histone cluster 3, H3
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL12A interleukin 12A
IL12B interleukin 12B
IL18 interleukin 18
IL1B interleukin 1, beta
IL6 interleukin 6
IREB2 iron-responsive element binding protein 2
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITLN1 intelectin 1 (galactofuranose binding)
KDM3A lysine (K)-specific demethylase 3A
LCN2 lipocalin 2
LIG3 ligase III, DNA, ATP-dependent
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCOLN1 mucolipin 1
MIOX myo-inositol oxygenase
MMP1 matrix metallopeptidase 1
MPO myeloperoxidase
MT1A metallothionein 1A
MT2A metallothionein 2A
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGB neuroglobin
NOS2 nitric oxide synthase 2, inducible
NQO1 NAD(P)H dehydrogenase, quinone 1
OCLN occludin
ODC1 ornithine decarboxylase 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POLB polymerase (DNA directed), beta
PON1 paraoxonase 1
POR P450 (cytochrome) oxidoreductase
PRNP prion protein
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RASD1 RAS, dexamethasone-induced 1
RRM2 ribonucleotide reductase M2
SELE selectin E
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORD sorbitol dehydrogenase
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STEAP2 STEAP family member 2, metalloreductase
STEAP3 STEAP family member 3, metalloreductase
STEAP4 STEAP family member 4
STK11 serine/threonine kinase 11
TERT telomerase reverse transcriptase
TF transferrin
TFR2 transferrin receptor 2
TFRC transferrin receptor
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TXN2 thioredoxin 2
UROD uroporphyrinogen decarboxylase
VCAM1 vascular cell adhesion molecule 1