Ionomycin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A very long-chain fatty acid that is docosa-10,16-dienoic acid which is substituted by methyl groups at positions 4, 6, 8, 12, 14, 18 and 20, by hydroxy groups at positions 11, 19 and 21, and by a (2',5-dimethyloctahydro-2,2'-bifuran-5-yl)ethanol group at position 21. An ionophore produced by Streptomyces conglobatus, it is used in research to raise the intracellular level of Ca(2+) and as a research tool to understand Ca(2+) transport across biological membranes. (Chemical Entities of Biological Interest Ontology, CHEBI_63954)
External Link http://ctdbase.org/detail.go?type=chem&acc=D015759
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Genes

80 genes/proteins interacting with the chemical Ionomycin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACTN1 actinin, alpha 1
ADM adrenomedullin
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
CALCA calcitonin-related polypeptide alpha
CALR calreticulin
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CD40LG CD40 ligand
CD86 CD86 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHUK conserved helix-loop-helix ubiquitous kinase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DRD3 dopamine receptor D3
EGF epidermal growth factor
EGR1 early growth response 1
FASLG Fas ligand (TNF superfamily, member 6)
FOS FBJ murine osteosarcoma viral oncogene homolog
GH1 growth hormone 1
HEXB hexosaminidase B (beta polypeptide)
HRH2 histamine receptor H2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFNG interferon, gamma
IL10 interleukin 10
IL1B interleukin 1, beta
IL2 interleukin 2
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
JUN jun proto-oncogene
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP1 lysosomal-associated membrane protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MYL9 myosin, light chain 9, regulatory
NCS1 neuronal calcium sensor 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PLD2 phospholipase D2
POU2F1 POU class 2 homeobox 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKCQ protein kinase C, theta
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTK2B protein tyrosine kinase 2 beta
RCAN1 regulator of calcineurin 1
SFTPB surfactant protein B
SFTPC surfactant protein C
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SOD2 superoxide dismutase 2, mitochondrial
STIM1 stromal interaction molecule 1
SYN1 synapsin I
TFRC transferrin receptor
TNF tumor necrosis factor
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
ZEB1 zinc finger E-box binding homeobox 1