Integrin alphaIIb beta3 signaling Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-354192
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Genes

27 proteins participating in the Integrin alphaIIb beta3 signaling pathway from the Reactome Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
BCAR1 breast cancer anti-estrogen resistance 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FN1 fibronectin 1
GRB2 growth factor receptor-bound protein 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
PDPK1 3-phosphoinositide dependent protein kinase 1
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TLN1 talin 1
VWF von Willebrand factor