Insulin Signaling(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP481_r82731
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Genes

163 proteins participating in the Insulin Signaling(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ARHGAP33 Rho GTPase activating protein 33
C8ORF44-SGK3 C8orf44-SGK3 readthrough
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CYTH3 cytohesin 3
EGR1 early growth response 1
EHD1 EH-domain containing 1
EHD2 EH-domain containing 2
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FLOT1 flotillin 1
FLOT2 flotillin 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GAB1 GRB2-associated binding protein 1
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRB2 growth factor receptor-bound protein 2
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GYG1 glycogenin 1
GYS1 glycogen synthase 1 (muscle)
GYS2 glycogen synthase 2 (liver)
HRAS Harvey rat sarcoma viral oncogene homolog
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPPL1 inositol polyphosphate phosphatase-like 1
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
JUN jun proto-oncogene
KIF3A kinesin family member 3A
KIF5B kinesin family member 5B
LIPE lipase, hormone-sensitive
LOC100996792 dual specificity mitogen-activated protein kinase kinase 3
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK4 mitogen-activated protein kinase 4
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MINK1 misshapen-like kinase 1
MIR3620 microRNA 3620
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYO1C myosin IC
PDPK1 3-phosphoinositide dependent protein kinase 1
PFKL phosphofructokinase, liver
PFKM phosphofructokinase, muscle
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PTEN phosphatase and tensin homolog
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRF protein tyrosine phosphatase, receptor type, F
RAB4A RAB4A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
REG1A regenerating islet-derived 1 alpha
RHEB Ras homolog enriched in brain
RHOJ ras homolog family member J
RHOQ ras homolog family member Q
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRAD Ras-related associated with diabetes
SGK1 serum/glucocorticoid regulated kinase 1
SGK2 serum/glucocorticoid regulated kinase 2
SGK3 serum/glucocorticoid regulated kinase family, member 3
SH2B2 SH2B adaptor protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SNAP23 synaptosomal-associated protein, 23kDa
SNAP25 synaptosomal-associated protein, 25kDa
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SORBS1 sorbin and SH3 domain containing 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SPHAR S-phase response (cyclin related)
SRF serum response factor (c-fos serum response element-binding transcription factor)
STX4 syntaxin 4
STXBP1 syntaxin binding protein 1
STXBP2 syntaxin binding protein 2
STXBP3 syntaxin binding protein 3
STXBP4 syntaxin binding protein 4
TBC1D4 TBC1 domain family, member 4
TRIB3 tribbles pseudokinase 3
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
XBP1 X-box binding protein 1