Infection Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The state of being infected such as from the introduction of a foreign agent such as serum, vaccine, antigenic substance or organism. (Experimental Factor Ontology, EFO_0000544)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D007239
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Genes

53 genes/proteins associated with the disease Infection from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CRP C-reactive protein, pentraxin-related 2.88009
POMC proopiomelanocortin 2.88009
TNF tumor necrosis factor 2.88009
MBL2 mannose-binding lectin (protein C) 2, soluble 2.88009
PEPD peptidase D 2.88009
BCL2 B-cell CLL/lymphoma 2 1.67289
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.66124
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.58724
TP53 tumor protein p53 1.58701
FAS Fas cell surface death receptor 1.55896
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.5382
IL4 interleukin 4 1.51531
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.50675
BAX BCL2-associated X protein 1.48838
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.47736
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.46961
TYMS thymidylate synthetase 1.46383
H2AFX H2A histone family, member X 1.42428
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.42183
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.41451
BIRC5 baculoviral IAP repeat containing 5 1.41313
ERBB2 erb-b2 receptor tyrosine kinase 2 1.38498
PARP1 poly (ADP-ribose) polymerase 1 1.35098
CAT catalase 1.32103
TOP2A topoisomerase (DNA) II alpha 170kDa 1.30451
IL6 interleukin 6 1.28456
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.27224
VEGFA vascular endothelial growth factor A 1.26638
JUN jun proto-oncogene 1.26576
SOD2 superoxide dismutase 2, mitochondrial 1.25557
BID BH3 interacting domain death agonist 1.25338
IL1B interleukin 1, beta 1.23137
FOXO1 forkhead box O1 1.2279
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.21141
CXCL8 chemokine (C-X-C motif) ligand 8 1.18685
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.17926
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.17034
VCAM1 vascular cell adhesion molecule 1 1.15357
BCL2L1 BCL2-like 1 1.14919
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.12973
MAPK1 mitogen-activated protein kinase 1 1.10211
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.09646
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.08549
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.06625
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.06479
MBP myelin basic protein 1.05648
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.04126
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.02896
MCL1 myeloid cell leukemia 1 1.02373
GSTP1 glutathione S-transferase pi 1 1.02225
TFPI2 tissue factor pathway inhibitor 2 1.0189
GSTM1 glutathione S-transferase mu 1 1.01587
MAPK3 mitogen-activated protein kinase 3 1.01249