IVD Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description isovaleryl-CoA dehydrogenase|Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] (NCBI Entrez Gene Database, 3712)
External Link http://www.ncbi.nlm.nih.gov/gene/3712
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Genes

7 interacting proteins for IVD from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TERF2 telomeric repeat binding factor 2
UBC ubiquitin C