Hypertension_Adrenal gland_GSE1674 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1674
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Genes

600 genes differentially expressed during Hypertension_Adrenal gland_GSE1674 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 4.51234
ZNF703 zinc finger protein 703 4.09718
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 3.96847
CLK1 CDC-like kinase 1 3.92591
CLCN3 chloride channel, voltage-sensitive 3 3.86502
MPDU1 mannose-P-dolichol utilization defect 1 3.84378
GTPBP2 GTP binding protein 2 3.67947
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 3.64063
RBM3 RNA binding motif (RNP1, RRM) protein 3 3.61595
BIN1 bridging integrator 1 3.41396
THUMPD1 THUMP domain containing 1 3.38839
PRKD3 protein kinase D3 3.3691
RAB5A RAB5A, member RAS oncogene family 3.328
TXNDC16 thioredoxin domain containing 16 3.19894
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 3.14046
ZNF207 zinc finger protein 207 3.10242
POLR1A polymerase (RNA) I polypeptide A, 194kDa 3.09687
SEC61G Sec61 gamma subunit 3.06664
ANKFY1 ankyrin repeat and FYVE domain containing 1 2.99228
CETN3 centrin, EF-hand protein, 3 2.98523
CALML4 calmodulin-like 4 2.9739
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.93547
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.92734
COPZ2 coatomer protein complex, subunit zeta 2 2.89434
GLO1 glyoxalase I 2.88933
RHOQ ras homolog family member Q 2.82095
PHB prohibitin 2.81736
RAB9A RAB9A, member RAS oncogene family 2.79468
STBD1 starch binding domain 1 2.76339
PHF12 PHD finger protein 12 2.76237
SELK selenoprotein K 2.73722
C1ORF158 chromosome 1 open reading frame 158 2.72904
RAD23B RAD23 homolog B (S. cerevisiae) 2.70341
RALY RALY heterogeneous nuclear ribonucleoprotein 2.67782
TMCO1 transmembrane and coiled-coil domains 1 2.6544
FKBP7 FK506 binding protein 7 2.64714
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 2.63134
RHOU ras homolog family member U 2.6269
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 2.61919
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.59871
TXN thioredoxin 2.59528
ACE2 angiotensin I converting enzyme 2 2.58014
NFE2L2 nuclear factor, erythroid 2-like 2 2.56492
SIN3A SIN3 transcription regulator family member A 2.54863
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.53083
PTCD3 pentatricopeptide repeat domain 3 2.48413
MAP3K3 mitogen-activated protein kinase kinase kinase 3 2.48186
MAX MYC associated factor X 2.47386
HOXB5 homeobox B5 2.42412
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2.38237
SPATA13 spermatogenesis associated 13 2.35571
GLTSCR2 glioma tumor suppressor candidate region gene 2 2.35291
EIF2A eukaryotic translation initiation factor 2A, 65kDa 2.34399
RUNX2 runt-related transcription factor 2 2.33808
EGLN2 egl-9 family hypoxia-inducible factor 2 2.33214
TAGLN transgelin 2.32837
SPTSSA serine palmitoyltransferase, small subunit A 2.31304
SLBP stem-loop binding protein 2.30978
GAS1 growth arrest-specific 1 2.30721
LYRM2 LYR motif containing 2 2.28941
MRPL48 mitochondrial ribosomal protein L48 2.2796
RPS7 ribosomal protein S7 2.27662
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.26652
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 2.25555
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.24598
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 2.23053
KCTD20 potassium channel tetramerization domain containing 20 2.2157
RPS11 ribosomal protein S11 2.21495
FAM50A family with sequence similarity 50, member A 2.20412
NXF1 nuclear RNA export factor 1 2.19054
HEPH hephaestin 2.17371
MEF2C myocyte enhancer factor 2C 2.17281
CD47 CD47 molecule 2.17105
DCN decorin 2.17092
TEK TEK tyrosine kinase, endothelial 2.1689
NLK nemo-like kinase 2.1673
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 2.1662
CAPRIN2 caprin family member 2 2.12811
SIAH2 siah E3 ubiquitin protein ligase 2 2.12199
TPD52 tumor protein D52 2.12076
TMEM185A transmembrane protein 185A 2.11671
CAPG capping protein (actin filament), gelsolin-like 2.10266
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.09766
BPGM 2,3-bisphosphoglycerate mutase 2.09759
TXN2 thioredoxin 2 2.06447
PPAP2B phosphatidic acid phosphatase type 2B 2.05109
MOGS mannosyl-oligosaccharide glucosidase 2.04967
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 2.02923
BZW1 basic leucine zipper and W2 domains 1 2.01512
DAGLB diacylglycerol lipase, beta 2.01261
IGFBP6 insulin-like growth factor binding protein 6 1.99666
RAB18 RAB18, member RAS oncogene family 1.98762
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 1.98337
CSRP1 cysteine and glycine-rich protein 1 1.981
IST1 increased sodium tolerance 1 homolog (yeast) 1.97994
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.97952
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.97842
DGUOK deoxyguanosine kinase 1.97045
FAM134A family with sequence similarity 134, member A 1.96333
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.96289
CPXM2 carboxypeptidase X (M14 family), member 2 1.96031
RPL7 ribosomal protein L7 1.92996
LBR lamin B receptor 1.92448
TSNAX translin-associated factor X 1.92334
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.91069
HFE hemochromatosis 1.90353
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 1.90198
MFN1 mitofusin 1 1.89522
TMTC2 transmembrane and tetratricopeptide repeat containing 2 1.88782
SRSF11 serine/arginine-rich splicing factor 11 1.88353
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 1.8745
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 1.87346
GSPT2 G1 to S phase transition 2 1.86425
RPL7A ribosomal protein L7a 1.8596
CSDE1 cold shock domain containing E1, RNA-binding 1.85545
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.82291
RPP21 ribonuclease P/MRP 21kDa subunit 1.81812
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.8043
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 1.79887
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 1.79666
CKAP5 cytoskeleton associated protein 5 1.79191
SHROOM3 shroom family member 3 1.78814
SLC30A9 solute carrier family 30 (zinc transporter), member 9 1.78524
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.78035
WDR43 WD repeat domain 43 1.77593
GNA14 guanine nucleotide binding protein (G protein), alpha 14 1.77414
OR4C3 olfactory receptor, family 4, subfamily C, member 3 1.77409
MBD1 methyl-CpG binding domain protein 1 1.76899
DCAF13 DDB1 and CUL4 associated factor 13 1.76379
PCBP2 poly(rC) binding protein 2 1.75788
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.7573
TNPO2 transportin 2 1.75415
MECP2 methyl CpG binding protein 2 1.7404
LRP1 low density lipoprotein receptor-related protein 1 1.72623
ATAD2B ATPase family, AAA domain containing 2B 1.71361
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.71324
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.68942
ANKRD13C ankyrin repeat domain 13C 1.68404
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.68144
TLN1 talin 1 1.68024
GHITM growth hormone inducible transmembrane protein 1.67656
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.67462
ZFAND5 zinc finger, AN1-type domain 5 1.67129
EEA1 early endosome antigen 1 1.66419
NDRG1 N-myc downstream regulated 1 1.66287
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 1.65295
KLF4 Kruppel-like factor 4 (gut) 1.65224
IGF2R insulin-like growth factor 2 receptor 1.6429
HSPE1 heat shock 10kDa protein 1 1.63745
BTG1 B-cell translocation gene 1, anti-proliferative 1.63296
PRDX2 peroxiredoxin 2 1.62433
HES1 hes family bHLH transcription factor 1 1.62425
LRRC58 leucine rich repeat containing 58 1.62053
PQLC1 PQ loop repeat containing 1 1.60279
FLII flightless I homolog (Drosophila) 1.60119
SNX14 sorting nexin 14 1.59691
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.58178
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 1.57751
STAG2 stromal antigen 2 1.57642
BAG3 BCL2-associated athanogene 3 1.57639
HAX1 HCLS1 associated protein X-1 1.5751
TCF4 transcription factor 4 1.57452
FANCG Fanconi anemia, complementation group G 1.57429
MRPL41 mitochondrial ribosomal protein L41 1.56705
YBX1 Y box binding protein 1 1.56647
LMO7 LIM domain 7 1.56301
DMRT1 doublesex and mab-3 related transcription factor 1 1.5615
PDCD6 programmed cell death 6 1.5505
SF3B5 splicing factor 3b, subunit 5, 10kDa 1.55046
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.54714
CP ceruloplasmin (ferroxidase) 1.54353
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 1.54203
GM2A GM2 ganglioside activator 1.53748
ERMP1 endoplasmic reticulum metallopeptidase 1 1.5374
UBE2G1 ubiquitin-conjugating enzyme E2G 1 1.52781
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.52479
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.51601
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.51269
RASA3 RAS p21 protein activator 3 1.50982
PNRC1 proline-rich nuclear receptor coactivator 1 1.50864
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.49593
TRIM59 tripartite motif containing 59 1.49394
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.49364
NPC1 Niemann-Pick disease, type C1 1.49226
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 1.49068
IVNS1ABP influenza virus NS1A binding protein 1.48472
CREBBP CREB binding protein 1.48199
PTTG1IP pituitary tumor-transforming 1 interacting protein 1.47811
TERF2 telomeric repeat binding factor 2 1.47443
MRPL24 mitochondrial ribosomal protein L24 1.46795
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.46552
CHMP5 charged multivesicular body protein 5 1.46133
UBQLN1 ubiquilin 1 1.4488
FAM102A family with sequence similarity 102, member A 1.44807
RGS2 regulator of G-protein signaling 2 1.44769
CINP cyclin-dependent kinase 2 interacting protein 1.44397
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.44264
ERRFI1 ERBB receptor feedback inhibitor 1 1.42772
TOR1B torsin family 1, member B (torsin B) 1.42719
AMOT angiomotin 1.42572
BTG2 BTG family, member 2 1.42161
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1.41784
F11R F11 receptor 1.41728
TNPO3 transportin 3 1.41723
RREB1 ras responsive element binding protein 1 1.41695
XDH xanthine dehydrogenase 1.41578
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 1.41113
TSPO translocator protein (18kDa) 1.40462
ERH enhancer of rudimentary homolog (Drosophila) 1.40378
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 1.39654
FAM103A1 family with sequence similarity 103, member A1 1.39263
MRPL54 mitochondrial ribosomal protein L54 1.39114
GPC3 glypican 3 1.39052
MEF2D myocyte enhancer factor 2D 1.3872
ZNF644 zinc finger protein 644 1.38558
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 1.38243
CDK8 cyclin-dependent kinase 8 1.38184
ZNRD1 zinc ribbon domain containing 1 1.37993
GADD45B growth arrest and DNA-damage-inducible, beta 1.37558
SBF2 SET binding factor 2 1.36682
TXNDC17 thioredoxin domain containing 17 1.36469
NCKAP1 NCK-associated protein 1 1.36231
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 1.35939
RERE arginine-glutamic acid dipeptide (RE) repeats 1.35851
TCF12 transcription factor 12 1.35768
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.34853
LITAF lipopolysaccharide-induced TNF factor 1.34794
XRN1 5'-3' exoribonuclease 1 1.34787
RNASE4 ribonuclease, RNase A family, 4 1.34102
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.34026
NRD1 nardilysin (N-arginine dibasic convertase) 1.3386
SUSD6 sushi domain containing 6 1.33788
TK2 thymidine kinase 2, mitochondrial 1.33679
MTM1 myotubularin 1 1.3341
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 1.33215
KLHL9 kelch-like family member 9 1.33137
RAD21 RAD21 homolog (S. pombe) 1.33116
NRIP1 nuclear receptor interacting protein 1 1.32841
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 1.32834
FAM32A family with sequence similarity 32, member A 1.32716
TBCA tubulin folding cofactor A 1.32484
PER1 period circadian clock 1 1.32113
FBXO45 F-box protein 45 1.31825
RBP1 retinol binding protein 1, cellular 1.31558
DCAF12 DDB1 and CUL4 associated factor 12 1.31215
HSPA4 heat shock 70kDa protein 4 1.30868
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.30859
SIPA1L2 signal-induced proliferation-associated 1 like 2 1.30684
TMED7 transmembrane emp24 protein transport domain containing 7 1.29839
NOP10 NOP10 ribonucleoprotein 1.29811
UGDH UDP-glucose 6-dehydrogenase 1.29635
MRPL45 mitochondrial ribosomal protein L45 1.29612
RPL10A ribosomal protein L10a 1.29555
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 1.29464
UBL3 ubiquitin-like 3 1.29168
CCNG2 cyclin G2 1.29008
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.28722
TSPAN12 tetraspanin 12 1.27962
TRIO trio Rho guanine nucleotide exchange factor 1.27776
TMEM165 transmembrane protein 165 1.27459
SVIL supervillin 1.2714
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.26856
IPO11 importin 11 1.26821
NAGK N-acetylglucosamine kinase 1.26648
HLA-DRA major histocompatibility complex, class II, DR alpha 1.26222
PAIP2 poly(A) binding protein interacting protein 2 1.26069
MED10 mediator complex subunit 10 1.25745
OAZ2 ornithine decarboxylase antizyme 2 1.2573
PROX1 prospero homeobox 1 1.25582
SMAD1 SMAD family member 1 1.25381
UBXN6 UBX domain protein 6 1.2506
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.25003
TMEM123 transmembrane protein 123 1.24782
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 1.24692
KDM5B lysine (K)-specific demethylase 5B 1.24673
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 1.24435
LIAS lipoic acid synthetase 1.24328
JTB jumping translocation breakpoint 1.24207
CIRBP cold inducible RNA binding protein 1.24111
TRAF3 TNF receptor-associated factor 3 1.24053
RAB28 RAB28, member RAS oncogene family 1.2358
MSH3 mutS homolog 3 1.23015
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.22327
OGN osteoglycin 1.22178
IL18 interleukin 18 1.21843
ZNFX1 zinc finger, NFX1-type containing 1 1.21831
CTAGE5 CTAGE family, member 5 1.21362
AMMECR1L AMMECR1-like 1.21169
RAD50 RAD50 homolog (S. cerevisiae) 1.20983
C14ORF166 chromosome 14 open reading frame 166 1.20928
SYF2 SYF2 pre-mRNA-splicing factor 1.20815
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 1.20673
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.19858
HARS histidyl-tRNA synthetase 1.19395
ANXA4 annexin A4 1.19369
SLC4A2 solute carrier family 4 (anion exchanger), member 2 1.19347
C1ORF43 chromosome 1 open reading frame 43 1.1883
C2ORF47 chromosome 2 open reading frame 47 1.18174
LCLAT1 lysocardiolipin acyltransferase 1 1.17805
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.17504

decreased expression

Symbol Name Standardized Value
PRDX1 peroxiredoxin 1 -4.30724
SEPT9 septin 9 -4.1308
RFK riboflavin kinase -4.06969
LMO2 LIM domain only 2 (rhombotin-like 1) -3.90565
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -3.5116
IL10RB interleukin 10 receptor, beta -3.37696
YIPF4 Yip1 domain family, member 4 -3.19157
MINOS1 mitochondrial inner membrane organizing system 1 -3.13533
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -3.11222
DDA1 DET1 and DDB1 associated 1 -3.07147
CXXC1 CXXC finger protein 1 -2.9372
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.9078
ZNF467 zinc finger protein 467 -2.85575
IFT88 intraflagellar transport 88 -2.83023
PEX5 peroxisomal biogenesis factor 5 -2.77747
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.65977
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.65304
CSNK2A1 casein kinase 2, alpha 1 polypeptide -2.59655
SYNJ2BP synaptojanin 2 binding protein -2.59567
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.58208
ATP13A3 ATPase type 13A3 -2.5744
MTOR mechanistic target of rapamycin (serine/threonine kinase) -2.55227
ADSS adenylosuccinate synthase -2.54822
COL5A1 collagen, type V, alpha 1 -2.54313
BRAP BRCA1 associated protein -2.53049
ATRAID all-trans retinoic acid-induced differentiation factor -2.47246
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.44818
ELAVL1 ELAV like RNA binding protein 1 -2.40639
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.34295
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.30947
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -2.29698
C1QB complement component 1, q subcomponent, B chain -2.25536
BCAP31 B-cell receptor-associated protein 31 -2.25133
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 -2.24732
TRAFD1 TRAF-type zinc finger domain containing 1 -2.24169
FBXO9 F-box protein 9 -2.22246
GJA5 gap junction protein, alpha 5, 40kDa -2.19626
GSTM5 glutathione S-transferase mu 5 -2.16378
PGAM1 phosphoglycerate mutase 1 (brain) -2.14847
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -2.14763
PRKD1 protein kinase D1 -2.11951
CAMLG calcium modulating ligand -2.11709
PEX7 peroxisomal biogenesis factor 7 -2.10983
UROS uroporphyrinogen III synthase -2.09271
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.09217
MRPS24 mitochondrial ribosomal protein S24 -2.08759
PPP6R3 protein phosphatase 6, regulatory subunit 3 -2.07878
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.05897
GBP4 guanylate binding protein 4 -2.0577
USF1 upstream transcription factor 1 -2.04473
BCL6B B-cell CLL/lymphoma 6, member B -2.03826
SWI5 SWI5 recombination repair homolog (yeast) -2.03825
AKAP1 A kinase (PRKA) anchor protein 1 -2.02026
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.01471
ABHD14A abhydrolase domain containing 14A -2.01223
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.01085
PLXND1 plexin D1 -2.00813
CHMP4C charged multivesicular body protein 4C -2.00736
METTL17 methyltransferase like 17 -1.9794
SMC6 structural maintenance of chromosomes 6 -1.96969
SAMD4B sterile alpha motif domain containing 4B -1.94705
GFER growth factor, augmenter of liver regeneration -1.93445
CD22 CD22 molecule -1.92805
APLN apelin -1.91439
SAMD10 sterile alpha motif domain containing 10 -1.91037
PC pyruvate carboxylase -1.8948
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) -1.88685
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -1.87609
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -1.85534
EPHB6 EPH receptor B6 -1.83621
DHRS3 dehydrogenase/reductase (SDR family) member 3 -1.83468
PDCL3 phosducin-like 3 -1.8279
GLTP glycolipid transfer protein -1.82083
FKBPL FK506 binding protein like -1.8146
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) -1.80964
CR1L complement component (3b/4b) receptor 1-like -1.79328
TPP1 tripeptidyl peptidase I -1.76702
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.76142
ANXA5 annexin A5 -1.76003
TSPAN7 tetraspanin 7 -1.75947
NMT1 N-myristoyltransferase 1 -1.75294
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -1.73577
TUFM Tu translation elongation factor, mitochondrial -1.7355
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa -1.73457
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -1.66355
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -1.63726
GSTP1 glutathione S-transferase pi 1 -1.62818
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -1.61741
PEPD peptidase D -1.61435
CNTN3 contactin 3 (plasmacytoma associated) -1.61408
TMEM208 transmembrane protein 208 -1.60915
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -1.59522
ATP13A2 ATPase type 13A2 -1.58506
EXOSC5 exosome component 5 -1.57738
TSSC4 tumor suppressing subtransferable candidate 4 -1.56842
ABLIM1 actin binding LIM protein 1 -1.5389
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -1.53864
MERTK MER proto-oncogene, tyrosine kinase -1.53599
PDIA6 protein disulfide isomerase family A, member 6 -1.51366
KLK3 kallikrein-related peptidase 3 -1.51007
STOM stomatin -1.50713
MRPS18A mitochondrial ribosomal protein S18A -1.50285
TIAM2 T-cell lymphoma invasion and metastasis 2 -1.49821
ANXA6 annexin A6 -1.49802
TMC6 transmembrane channel-like 6 -1.49483
CEL carboxyl ester lipase -1.4879
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -1.48743
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -1.4842
C9ORF16 chromosome 9 open reading frame 16 -1.4774
HTT huntingtin -1.46759
KIAA0100 KIAA0100 -1.45698
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.44927
EIF2D eukaryotic translation initiation factor 2D -1.44596
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.44178
GOLGA7 golgin A7 -1.43947
MBD2 methyl-CpG binding domain protein 2 -1.43891
PHKA2 phosphorylase kinase, alpha 2 (liver) -1.42844
ACR acrosin -1.41896
PCYOX1 prenylcysteine oxidase 1 -1.41298
MCAM melanoma cell adhesion molecule -1.40578
ENG endoglin -1.40537
BBS9 Bardet-Biedl syndrome 9 -1.40373
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.40242
AK2 adenylate kinase 2 -1.40126
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.40027
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -1.39892
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 -1.39092
SLC35B1 solute carrier family 35, member B1 -1.38942
RP9 retinitis pigmentosa 9 (autosomal dominant) -1.38689
IRF7 interferon regulatory factor 7 -1.38677
GALM galactose mutarotase (aldose 1-epimerase) -1.38375
CHIC1 cysteine-rich hydrophobic domain 1 -1.37806
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -1.37092
TP53INP1 tumor protein p53 inducible nuclear protein 1 -1.36723
SRI sorcin -1.35985
STK25 serine/threonine kinase 25 -1.35917
ZMYND8 zinc finger, MYND-type containing 8 -1.3575
MED12 mediator complex subunit 12 -1.35321
JAGN1 jagunal homolog 1 (Drosophila) -1.35022
MAPK12 mitogen-activated protein kinase 12 -1.346
NFXL1 nuclear transcription factor, X-box binding-like 1 -1.34152
MRPS12 mitochondrial ribosomal protein S12 -1.33433
ANGPTL4 angiopoietin-like 4 -1.32794
EVX2 even-skipped homeobox 2 -1.32648
MED24 mediator complex subunit 24 -1.32609
EDF1 endothelial differentiation-related factor 1 -1.31969
SOX2 SRY (sex determining region Y)-box 2 -1.31824
MRPS5 mitochondrial ribosomal protein S5 -1.31462
FGFR3 fibroblast growth factor receptor 3 -1.30786
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -1.30675
PFDN5 prefoldin subunit 5 -1.30408
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.30224
PHKB phosphorylase kinase, beta -1.30183
WT1 Wilms tumor 1 -1.28889
MAPT microtubule-associated protein tau -1.28599
HMOX2 heme oxygenase 2 -1.27416
CASQ2 calsequestrin 2 (cardiac muscle) -1.27376
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -1.26675
HTRA2 HtrA serine peptidase 2 -1.26107
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -1.25609
ROMO1 reactive oxygen species modulator 1 -1.25389
UTS2R urotensin 2 receptor -1.24432
MRPS2 mitochondrial ribosomal protein S2 -1.24386
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -1.24302
MUT methylmalonyl CoA mutase -1.24229
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.23528
HOXC8 homeobox C8 -1.23234
C16ORF89 chromosome 16 open reading frame 89 -1.23049
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 -1.22836
TMEM37 transmembrane protein 37 -1.22629
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -1.22296
SLC38A4 solute carrier family 38, member 4 -1.2192
ZFP36L2 ZFP36 ring finger protein-like 2 -1.21621
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -1.21382
ASGR1 asialoglycoprotein receptor 1 -1.20868
MTX2 metaxin 2 -1.1967
BIRC6 baculoviral IAP repeat containing 6 -1.19283
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -1.19164
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -1.19151
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -1.18752
CDK5 cyclin-dependent kinase 5 -1.18665
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 -1.18123
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -1.17981
RNF14 ring finger protein 14 -1.17661
LRP6 low density lipoprotein receptor-related protein 6 -1.1744
RALB v-ral simian leukemia viral oncogene homolog B -1.17425
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 -1.17413
MECOM MDS1 and EVI1 complex locus -1.17317
AARS alanyl-tRNA synthetase -1.17189
CDC20 cell division cycle 20 -1.1715
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.17112
CDCA3 cell division cycle associated 3 -1.16787
TCEA1 transcription elongation factor A (SII), 1 -1.15998
TMEM134 transmembrane protein 134 -1.15292
LALBA lactalbumin, alpha- -1.1443
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -1.14366
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -1.14354
NUCB1 nucleobindin 1 -1.14116
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -1.13503
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 -1.1335
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled -1.1296
FZD3 frizzled class receptor 3 -1.12693
PTAFR platelet-activating factor receptor -1.12355
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 -1.1214
EPN2 epsin 2 -1.11868
TYSND1 trypsin domain containing 1 -1.11548
WIPI2 WD repeat domain, phosphoinositide interacting 2 -1.11432
GJD2 gap junction protein, delta 2, 36kDa -1.11327
NEK6 NIMA-related kinase 6 -1.10761
C9ORF72 chromosome 9 open reading frame 72 -1.10498
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.10442
FBXW4 F-box and WD repeat domain containing 4 -1.1027
LYPLA1 lysophospholipase I -1.10263
H2AFV H2A histone family, member V -1.10062
TLR7 toll-like receptor 7 -1.09852
LAPTM5 lysosomal protein transmembrane 5 -1.09454
ARF3 ADP-ribosylation factor 3 -1.09111
PROP1 PROP paired-like homeobox 1 -1.08917
MAPK6 mitogen-activated protein kinase 6 -1.08855
HIC1 hypermethylated in cancer 1 -1.08246
BCKDK branched chain ketoacid dehydrogenase kinase -1.07958
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -1.07893
DSCR3 Down syndrome critical region 3 -1.07159
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -1.07106
DHRSX dehydrogenase/reductase (SDR family) X-linked -1.06636
DHPS deoxyhypusine synthase -1.06534
MRPS26 mitochondrial ribosomal protein S26 -1.06421
CTSD cathepsin D -1.06387
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.06255
CDK2 cyclin-dependent kinase 2 -1.06062
METTL9 methyltransferase like 9 -1.05953
SAC3D1 SAC3 domain containing 1 -1.05945
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) -1.05921
STARD7 StAR-related lipid transfer (START) domain containing 7 -1.05806
ATF3 activating transcription factor 3 -1.05782
CLCN1 chloride channel, voltage-sensitive 1 -1.05768
SETD6 SET domain containing 6 -1.05616
LRPPRC leucine-rich pentatricopeptide repeat containing -1.05483
KLF9 Kruppel-like factor 9 -1.05387
HDAC6 histone deacetylase 6 -1.04973
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -1.04802
COA3 cytochrome c oxidase assembly factor 3 -1.04714
LEMD1 LEM domain containing 1 -1.04467
ST7-AS2 ST7 antisense RNA 2 -1.04459
SELPLG selectin P ligand -1.04288
OR13J1 olfactory receptor, family 13, subfamily J, member 1 -1.04196
PQLC3 PQ loop repeat containing 3 -1.04166
CD93 CD93 molecule -1.038
FAM69B family with sequence similarity 69, member B -1.0365
ZNF385A zinc finger protein 385A -1.03639
HBEGF heparin-binding EGF-like growth factor -1.03555
PTCD2 pentatricopeptide repeat domain 2 -1.03491
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -1.03414
WNK1 WNK lysine deficient protein kinase 1 -1.0333
MINPP1 multiple inositol-polyphosphate phosphatase 1 -1.03171
TXNIP thioredoxin interacting protein -1.03068
CST3 cystatin C -1.03014
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -1.02989
MAP2K3 mitogen-activated protein kinase kinase 3 -1.02867
MRPS25 mitochondrial ribosomal protein S25 -1.02703
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -1.02109
STRA6 stimulated by retinoic acid 6 -1.01866
MGST1 microsomal glutathione S-transferase 1 -1.01713
TIMELESS timeless circadian clock -1.01396
CHMP7 charged multivesicular body protein 7 -1.01373
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) -1.01326
EFTUD1 elongation factor Tu GTP binding domain containing 1 -1.01211
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -1.00914
ELOF1 elongation factor 1 homolog (S. cerevisiae) -1.00673
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -1.00567
C1QC complement component 1, q subcomponent, C chain -1.00444
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 -1.00068
TRIP6 thyroid hormone receptor interactor 6 -0.999754
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.995727
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative) -0.995184
CD19 CD19 molecule -0.992154
PLA2G2C phospholipase A2, group IIC -0.990209
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.990082
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -0.989756
SEZ6 seizure related 6 homolog (mouse) -0.988179
ADRBK1 adrenergic, beta, receptor kinase 1 -0.98585
CTNND1 catenin (cadherin-associated protein), delta 1 -0.985496
GFM1 G elongation factor, mitochondrial 1 -0.984336
RASAL3 RAS protein activator like 3 -0.983309
EMC8 ER membrane protein complex subunit 8 -0.981875
PTOV1 prostate tumor overexpressed 1 -0.981215
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.97908
PSEN2 presenilin 2 -0.978177
SNX5 sorting nexin 5 -0.977921
COL7A1 collagen, type VII, alpha 1 -0.976804
CECR6 cat eye syndrome chromosome region, candidate 6 -0.974798
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) -0.973184
CXCL12 chemokine (C-X-C motif) ligand 12 -0.972482
MRPL4 mitochondrial ribosomal protein L4 -0.969684
SOX13 SRY (sex determining region Y)-box 13 -0.969668
PRKCSH protein kinase C substrate 80K-H -0.966289
MVP major vault protein -0.965998
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.962307
SIDT2 SID1 transmembrane family, member 2 -0.962073
HIF3A hypoxia inducible factor 3, alpha subunit -0.960325