Heme Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A heme is any tetrapyrrolic chelate of iron. (Chemical Entities of Biological Interest Ontology, CHEBI_30413)
External Link http://www.hmdb.ca/metabolites/HMDB03178
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Genes

165 interacting proteins for the Heme metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ALAD aminolevulinate dehydratase
ALAS1 5'-aminolevulinate synthase 1
ALAS2 5'-aminolevulinate synthase 2
AMBP alpha-1-microglobulin/bikunin precursor
AOX1 aldehyde oxidase 1
BLVRA biliverdin reductase A
BLVRB biliverdin reductase B
CAT catalase
CBS cystathionine-beta-synthase
CD163 CD163 molecule
CDC37 cell division cycle 37
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
COX5A cytochrome c oxidase subunit Va
CPOX coproporphyrinogen oxidase
CYB561 cytochrome b561
CYB561D1 cytochrome b561 family, member D1
CYB561D2 cytochrome b561 family, member D2
CYB5A cytochrome b5 type A (microsomal)
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYB5D1 cytochrome b5 domain containing 1
CYB5D2 cytochrome b5 domain containing 2
CYB5R4 cytochrome b5 reductase 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYBRD1 cytochrome b reductase 1
CYC1 cytochrome c-1
CYCS cytochrome c, somatic
CYGB cytoglobin
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EPX eosinophil peroxidase
FA2H fatty acid 2-hydroxylase
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FADS3 fatty acid desaturase 3
FECH ferrochelatase
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FRRS1 ferric-chelate reductase 1
FXN frataxin
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HBD hemoglobin, delta
HBE1 hemoglobin, epsilon 1
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HBM hemoglobin, mu
HBQ1 hemoglobin, theta 1
HBZ hemoglobin, zeta
HCCS holocytochrome c synthase
HEBP1 heme binding protein 1
HEBP2 heme binding protein 2
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HFE hemochromatosis
HMBS hydroxymethylbilane synthase
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HPX hemopexin
HRG histidine-rich glycoprotein
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LPO lactoperoxidase
MB myoglobin
MPO myeloperoxidase
NENF neudesin neurotrophic factor
NFE2 nuclear factor, erythroid 2
NFE2L1 nuclear factor, erythroid 2-like 1
NGB neuroglobin
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NRF1 nuclear respiratory factor 1
PGRMC1 progesterone receptor membrane component 1
PGRMC2 progesterone receptor membrane component 2
POR P450 (cytochrome) oxidoreductase
PPOX protoporphyrinogen oxidase
PRDM2 PR domain containing 2, with ZNF domain
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PXDN peroxidasin
PXDNL peroxidasin-like
RSAD2 radical S-adenosyl methionine domain containing 2
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP2 STEAP family member 2, metalloreductase
STEAP3 STEAP family member 3, metalloreductase
STEAP4 STEAP family member 4
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUOX sulfite oxidase
TBXAS1 thromboxane A synthase 1 (platelet)
TF transferrin
TPO thyroid peroxidase
TSPO translocator protein (18kDa)
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
UQCRH ubiquinol-cytochrome c reductase hinge protein
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase