Heme biosynthesis Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. (Gene Ontology, GO_0006783)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-189451
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Genes

11 proteins participating in the Heme biosynthesis pathway from the Reactome Pathways dataset.

Symbol Name
ALAD aminolevulinate dehydratase
ALAS1 5'-aminolevulinate synthase 1
ALAS2 5'-aminolevulinate synthase 2
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPOX coproporphyrinogen oxidase
FECH ferrochelatase
HMBS hydroxymethylbilane synthase
PPOX protoporphyrinogen oxidase
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase