Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A4C1-01A-11R-A24H-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

273 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A4C1-01A-11R-A24H-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACACA acetyl-CoA carboxylase alpha
ACLY ATP citrate lyase
ACOT11 acyl-CoA thioesterase 11
ACSS2 acyl-CoA synthetase short-chain family member 2
ADAMTSL5 ADAMTS-like 5
ADGRE2 adhesion G protein-coupled receptor E2
ALAS2 5'-aminolevulinate synthase 2
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ANGPT4 angiopoietin 4
ANO9 anoctamin 9
APOL4 apolipoprotein L, 4
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP10D ATPase, class V, type 10D
AVPR1A arginine vasopressin receptor 1A
AZI2 5-azacytidine induced 2
BCLAF1 BCL2-associated transcription factor 1
BTBD11 BTB (POZ) domain containing 11
BTBD7 BTB (POZ) domain containing 7
BTNL2 butyrophilin-like 2
C14ORF1 chromosome 14 open reading frame 1
C17ORF105 chromosome 17 open reading frame 105
C20ORF197 chromosome 20 open reading frame 197
C2ORF16 chromosome 2 open reading frame 16
C3ORF67 chromosome 3 open reading frame 67
C4ORF32 chromosome 4 open reading frame 32
CA1 carbonic anhydrase I
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CCDC70 coiled-coil domain containing 70
CCNYL1 cyclin Y-like 1
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEP170B centrosomal protein 170B
CHD1 chromodomain helicase DNA binding protein 1
CHURC1 churchill domain containing 1
CLCA2 chloride channel accessory 2
CLCN3 chloride channel, voltage-sensitive 3
CMTR2 cap methyltransferase 2
CNGA1 cyclic nucleotide gated channel alpha 1
CNTN1 contactin 1
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPXCR1 CPX chromosome region, candidate 1
CXORF49B chromosome X open reading frame 49B
CYB5R2 cytochrome b5 reductase 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCP1A decapping mRNA 1A
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DOCK4 dedicator of cytokinesis 4
DOCK6 dedicator of cytokinesis 6
DSCAM Down syndrome cell adhesion molecule
DSG3 desmoglein 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EGR4 early growth response 4
EIF5 eukaryotic translation initiation factor 5
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELOVL6 ELOVL fatty acid elongase 6
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA1 EPH receptor A1
EPS15 epidermal growth factor receptor pathway substrate 15
EREG epiregulin
ERI1 exoribonuclease 1
ESRP2 epithelial splicing regulatory protein 2
EXOC5 exocyst complex component 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM169A family with sequence similarity 169, member A
FAM86B2 family with sequence similarity 86, member B2
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1
FMN1 formin 1
FOXP1 forkhead box P1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GGT8P gamma-glutamyltransferase 8 pseudogene
GMFB glia maturation factor, beta
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GOLGA4 golgin A4
GOLGA5 golgin A5
GPATCH2L G patch domain containing 2-like
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GSDMC gasdermin C
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
HAPLN1 hyaluronan and proteoglycan link protein 1
HBEGF heparin-binding EGF-like growth factor
HDGFL1 hepatoma derived growth factor-like 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HEATR6 HEAT repeat containing 6
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IL18 interleukin 18
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INSIG1 insulin induced gene 1
IREB2 iron-responsive element binding protein 2
KDM1B lysine (K)-specific demethylase 1B
KIAA0922 KIAA0922
KIAA1033 KIAA1033
KIF3A kinesin family member 3A
KLHL8 kelch-like family member 8
KLK10 kallikrein-related peptidase 10
KPNA5 karyopherin alpha 5 (importin alpha 6)
L3MBTL3 l(3)mbt-like 3 (Drosophila)
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LDLR low density lipoprotein receptor
LIG4 ligase IV, DNA, ATP-dependent
LINC00696 long intergenic non-protein coding RNA 696
LINC01465 long intergenic non-protein coding RNA 1465
LINS lines homolog (Drosophila)
LIPG lipase, endothelial
LOC646999 akirin 1 pseudogene
LPIN1 lipin 1
LPPR5 lipid phosphate phosphatase-related protein type 5
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MACROD2 MACRO domain containing 2
MALT1 MALT1 paracaspase
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MASP2 mannan-binding lectin serine peptidase 2
MCM9 minichromosome maintenance complex component 9
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MGC16025 uncharacterized LOC85009
MLEC malectin
MOB1B MOB kinase activator 1B
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MREG melanoregulin
MRGPRX4 MAS-related GPR, member X4
MSH3 mutS homolog 3
MSMO1 methylsterol monooxygenase 1
MST1R macrophage stimulating 1 receptor
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTNR1B melatonin receptor 1B
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAV3 neuron navigator 3
NBEAL2 neurobeachin-like 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NIPAL1 NIPA-like domain containing 1
NLRP10 NLR family, pyrin domain containing 10
NUMB numb homolog (Drosophila)
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
NWD2 NACHT and WD repeat domain containing 2
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR2B11 olfactory receptor, family 2, subfamily B, member 11
OR4Q3 olfactory receptor, family 4, subfamily Q, member 3
OR51G1 olfactory receptor, family 51, subfamily G, member 1 (gene/pseudogene)
OR5E1P olfactory receptor, family 5, subfamily E, member 1 pseudogene
OR5P2 olfactory receptor, family 5, subfamily P, member 2
OR7D2 olfactory receptor, family 7, subfamily D, member 2
PANK3 pantothenate kinase 3
PAPOLA poly(A) polymerase alpha
PCDHGB6 protocadherin gamma subfamily B, 6
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE12 phosphodiesterase 12
PEG10 paternally expressed 10
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PKP2 plakophilin 2
PLA2G4E phospholipase A2, group IVE
PLCD1 phospholipase C, delta 1
PLCH2 phospholipase C, eta 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLK2 polo-like kinase 2
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PRDM5 PR domain containing 5
PRMT3 protein arginine methyltransferase 3
PRMT6 protein arginine methyltransferase 6
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRG protein tyrosine phosphatase, receptor type, G
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB38 RAB38, member RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBM12 RNA binding motif protein 12
RBM45 RNA binding motif protein 45
RCOR1 REST corepressor 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RLBP1 retinaldehyde binding protein 1
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPE65 retinal pigment epithelium-specific protein 65kDa
RUFY2 RUN and FYVE domain containing 2
RUSC1-AS1 RUSC1 antisense RNA 1
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SGPP1 sphingosine-1-phosphate phosphatase 1
SHROOM2 shroom family member 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35F4 solute carrier family 35, member F4
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SLFN12 schlafen family member 12
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNORA24 small nucleolar RNA, H/ACA box 24
SNX30 sorting nexin family member 30
SOCS4 suppressor of cytokine signaling 4
SOCS6 suppressor of cytokine signaling 6
SOWAHC sosondowah ankyrin repeat domain family member C
SPIN4 spindlin family, member 4
SPRED3 sprouty-related, EVH1 domain containing 3
SPTBN5 spectrin, beta, non-erythrocytic 5
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQLE squalene epoxidase
SRBD1 S1 RNA binding domain 1
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
STARD4 StAR-related lipid transfer (START) domain containing 4
STRIP2 striatin interacting protein 2
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX17 syntaxin 17
STX6 syntaxin 6
STYX serine/threonine/tyrosine interacting protein
SV2C synaptic vesicle glycoprotein 2C
SYNJ2BP synaptojanin 2 binding protein
SZT2 seizure threshold 2 homolog (mouse)
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TBX18 T-box 18
TDG thymine-DNA glycosylase
TDP1 tyrosyl-DNA phosphodiesterase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TJP2 tight junction protein 2
TLE4 transducin-like enhancer of split 4
TMCC3 transmembrane and coiled-coil domain family 3
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM154 transmembrane protein 154
TMEM167A transmembrane protein 167A
TMEM30B transmembrane protein 30B
TMEM89 transmembrane protein 89
TPMT thiopurine S-methyltransferase
TPRXL tetra-peptide repeat homeobox-like
TRIM36 tripartite motif containing 36
TRIML2 tripartite motif family-like 2
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TTC8 tetratricopeptide repeat domain 8
TUBGCP5 tubulin, gamma complex associated protein 5
TWF1 twinfilin actin binding protein 1
UFL1 UFM1-specific ligase 1
USP48 ubiquitin specific peptidase 48
VAX1 ventral anterior homeobox 1
XG Xg blood group
XIST X inactive specific transcript (non-protein coding)
ZC3H14 zinc finger CCCH-type containing 14
ZDHHC21 zinc finger, DHHC-type containing 21
ZFHX4 zinc finger homeobox 4
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF35 zinc finger protein 35
ZNF562 zinc finger protein 562
ZNF699 zinc finger protein 699
ZNF800 zinc finger protein 800
ZNF860 zinc finger protein 860
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1

low expression

Symbol Name
STAG2 stromal antigen 2
ZNF480 zinc finger protein 480