Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4Z9-01A-11R-A24Z-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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289 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4Z9-01A-11R-A24Z-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADAM21 ADAM metallopeptidase domain 21
ADAM21P1 ADAM metallopeptidase domain 21 pseudogene 1
ADGRG3 adhesion G protein-coupled receptor G3
AFAP1L1 actin filament associated protein 1-like 1
AGXT alanine-glyoxylate aminotransferase
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
ALDOB aldolase B, fructose-bisphosphate
AMBP alpha-1-microglobulin/bikunin precursor
AMOTL2 angiomotin like 2
ANKRD13C ankyrin repeat domain 13C
ANKRD52 ankyrin repeat domain 52
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B
ANLN anillin, actin binding protein
ANO1 anoctamin 1, calcium activated chloride channel
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOC4 apolipoprotein C-IV
APOH apolipoprotein H (beta-2-glycoprotein I)
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ASPDH aspartate dehydrogenase domain containing
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG2B autophagy related 2B
ATG9A autophagy related 9A
AUNIP aurora kinase A and ninein interacting protein
AVPI1 arginine vasopressin-induced 1
BMS1P5 BMS1 ribosome biogenesis factor pseudogene 5
BREA2 breast cancer estrogen-induced apoptosis 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF54 chromosome 10 open reading frame 54
C17ORF105 chromosome 17 open reading frame 105
C19ORF71 chromosome 19 open reading frame 71
C2ORF48 chromosome 2 open reading frame 48
C2ORF66 chromosome 2 open reading frame 66
C3ORF79 chromosome 3 open reading frame 79
C4ORF32 chromosome 4 open reading frame 32
C6ORF25 chromosome 6 open reading frame 25
C8A complement component 8, alpha polypeptide
CASC5 cancer susceptibility candidate 5
CATSPER4 cation channel, sperm associated 4
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC163P coiled-coil domain containing 163, pseudogene
CCL21 chemokine (C-C motif) ligand 21
CCNB2 cyclin B2
CCND1 cyclin D1
CCNK cyclin K
CD200R1L CD200 receptor 1-like
CDC27 cell division cycle 27
CENPE centromere protein E, 312kDa
CEP170B centrosomal protein 170B
CEP55 centrosomal protein 55kDa
CFHR2 complement factor H-related 2
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHUK conserved helix-loop-helix ubiquitous kinase
CLASP2 cytoplasmic linker associated protein 2
CLN5 ceroid-lipofuscinosis, neuronal 5
COL27A1 collagen, type XXVII, alpha 1
COPS7B COP9 signalosome subunit 7B
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CSPG4 chondroitin sulfate proteoglycan 4
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DEFB131 defensin, beta 131
DEPDC1B DEP domain containing 1B
DHCR7 7-dehydrocholesterol reductase
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DLEU2L deleted in lymphocytic leukemia 2-like
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNA2 DNA replication helicase/nuclease 2
DONSON downstream neighbor of SON
DPRXP4 divergent-paired related homeobox pseudogene 4
EFCAB11 EF-hand calcium binding domain 11
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4A3 eukaryotic translation initiation factor 4A3
EIF5 eukaryotic translation initiation factor 5
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPPK1 epiplakin 1
ERCC8 excision repair cross-complementation group 8
F13B coagulation factor XIII, B polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
F9 coagulation factor IX
FADD Fas (TNFRSF6)-associated via death domain
FAM138F family with sequence similarity 138, member F
FAM71F2 family with sequence similarity 71, member F2
FANCD2 Fanconi anemia, complementation group D2
FANCM Fanconi anemia, complementation group M
FBXL2 F-box and leucine-rich repeat protein 2
FBXL3 F-box and leucine-rich repeat protein 3
FBXO33 F-box protein 33
FCF1 FCF1 rRNA-processing protein
FKBP1AP1 FK506 binding protein 1A, 12kDa pseudogene 1
FLJ42627 uncharacterized LOC645644
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT4 fms-related tyrosine kinase 4
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FN3KRP fructosamine 3 kinase related protein
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
GAL galanin/GMAP prepropeptide
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GLRX5 glutaredoxin 5
GMFB glia maturation factor, beta
GOLGA1 golgin A1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR182 G protein-coupled receptor 182
GRAPL GRB2-related adaptor protein-like
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GSDMC gasdermin C
GUCA1B guanylate cyclase activator 1B (retina)
HAR1A highly accelerated region 1A (non-protein coding)
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HIST1H2BL histone cluster 1, H2bl
HPR haptoglobin-related protein
HPX hemopexin
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFNA10 interferon, alpha 10
IGHMBP2 immunoglobulin mu binding protein 2
IMPAD1 inositol monophosphatase domain containing 1
IQGAP3 IQ motif containing GTPase activating protein 3
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITPK1 inositol-tetrakisphosphate 1-kinase
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
JKAMP JNK1/MAPK8-associated membrane protein
KCP kielin/chordin-like protein
KIAA0895 KIAA0895
KIF11 kinesin family member 11
KIF18B kinesin family member 18B
KIF1BP KIF1 binding protein
KIF23 kinesin family member 23
KIF26A kinesin family member 26A
KNG1 kininogen 1
KTN1 kinectin 1 (kinesin receptor)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAPTM4A lysosomal protein transmembrane 4 alpha
LINC00052 long intergenic non-protein coding RNA 52
LINC00242 long intergenic non-protein coding RNA 242
LINC00482 long intergenic non-protein coding RNA 482
LMO7 LIM domain 7
LOC285593 uncharacterized LOC285593
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRR1 leucine rich repeat protein 1
LY6G5B lymphocyte antigen 6 complex, locus G5B
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCM10 minichromosome maintenance complex component 10
MCMBP minichromosome maintenance complex binding protein
METTL6 methyltransferase like 6
MINK1 misshapen-like kinase 1
MISP mitotic spindle positioning
MORC3 MORC family CW-type zinc finger 3
MRGPRF MAS-related GPR, member F
MRPL21 mitochondrial ribosomal protein L21
MRPS6 mitochondrial ribosomal protein S6
MRS2 MRS2 magnesium transporter
MTBP MDM2 binding protein
MTFR2 mitochondrial fission regulator 2
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYCT1 myc target 1
MYEOV myeloma overexpressed
MYO19 myosin XIX
MYO1G myosin IG
NAV3 neuron navigator 3
NCAPH non-SMC condensin I complex, subunit H
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEMF nuclear export mediator factor
NPY4R neuropeptide Y receptor Y4
NUDCD2 NudC domain containing 2
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
ORAOV1 oral cancer overexpressed 1
OTOP2 otopetrin 2
OTOP3 otopetrin 3
OTUD1 OTU deubiquitinase 1
PADI4 peptidyl arginine deiminase, type IV
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCDHGB3 protocadherin gamma subfamily B, 3
PCDHGB5 protocadherin gamma subfamily B, 5
PCDHGB6 protocadherin gamma subfamily B, 6
PDCD6IP programmed cell death 6 interacting protein
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLG plasminogen
PLSCR1 phospholipid scramblase 1
PNMA1 paraneoplastic Ma antigen 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRPF38B pre-mRNA processing factor 38B
PRPF39 pre-mRNA processing factor 39
PRSS42 protease, serine, 42
PTBP1 polypyrimidine tract binding protein 1
PTGR2 prostaglandin reductase 2
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PYGL phosphorylase, glycogen, liver
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RBM44 RNA binding motif protein 44
RBMS2 RNA binding motif, single stranded interacting protein 2
RBSN rabenosyn, RAB effector
RNF219 ring finger protein 219
RPL23AP64 ribosomal protein L23a pseudogene 64
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN3A sodium channel, voltage gated, type III alpha subunit
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHCBP1 SHC SH2-domain binding protein 1
SIKE1 suppressor of IKBKE 1
SKA2 spindle and kinetochore associated complex subunit 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC22A14 solute carrier family 22, member 14
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMNDC1 survival motor neuron domain containing 1
SNHG1 small nucleolar RNA host gene 1
SNORA2A small nucleolar RNA, H/ACA box 2A
SNORA71C small nucleolar RNA, H/ACA box 71C
SP6 Sp6 transcription factor
SPDL1 spindle apparatus coiled-coil protein 1
SPOPL speckle-type POZ protein-like
SRSF4 serine/arginine-rich splicing factor 4
STRIP2 striatin interacting protein 2
SYNE2 spectrin repeat containing, nuclear envelope 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TARSL2 threonyl-tRNA synthetase-like 2
TAS2R10 taste receptor, type 2, member 10
TAS2R5 taste receptor, type 2, member 5
TAT tyrosine aminotransferase
TBC1D26 TBC1 domain family, member 26
TBC1D29 TBC1 domain family, member 29
TBC1D3P2 TBC1 domain family, member 3 pseudogene 2
TDP1 tyrosyl-DNA phosphodiesterase 1
TDRD1 tudor domain containing 1
TEX19 testis expressed 19
TGM2 transglutaminase 2
TMEM109 transmembrane protein 109
TMEM200B transmembrane protein 200B
TMEM209 transmembrane protein 209
TMEM237 transmembrane protein 237
TONSL tonsoku-like, DNA repair protein
TPCN2 two pore segment channel 2
TRIM69 tripartite motif containing 69
TTK TTK protein kinase
TTR transthyretin
TUBGCP5 tubulin, gamma complex associated protein 5
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UCA1 urothelial cancer associated 1 (non-protein coding)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UNC5A unc-5 homolog A (C. elegans)
USH1G Usher syndrome 1G (autosomal recessive)
VCPKMT valosin containing protein lysine (K) methyltransferase
WDHD1 WD repeat and HMG-box DNA binding protein 1
WWC1 WW and C2 domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H14 zinc finger CCCH-type containing 14
ZFP42 ZFP42 zinc finger protein
ZFP57 ZFP57 zinc finger protein
ZGRF1 zinc finger, GRF-type containing 1
ZNF114 zinc finger protein 114
ZWILCH zwilch kinetochore protein

low expression

Symbol Name
NF2 neurofibromin 2 (merlin)
RAB35 RAB35, member RAS oncogene family
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SECISBP2 SECIS binding protein 2