Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6995-01A-31R-2016-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Head and Neck squamous cell carcinoma_HNSC (The Cancer Genome Atlas)
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Genes

376 genes with high or low expression in Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6995-01A-31R-2016-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD16A abhydrolase domain containing 16A
ACER2 alkaline ceramidase 2
ACP1 acid phosphatase 1, soluble
ACP2 acid phosphatase 2, lysosomal
ACSL5 acyl-CoA synthetase long-chain family member 5
ACY3 aminoacylase 3
ADA adenosine deaminase
ADAP1 ArfGAP with dual PH domains 1
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADGRF3 adhesion G protein-coupled receptor F3
ADIRF adipogenesis regulatory factor
AIM2 absent in melanoma 2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOA aldolase A, fructose-bisphosphate
ANO1 anoctamin 1, calcium activated chloride channel
ANO3 anoctamin 3
ANXA2 annexin A2
ANXA2P1 annexin A2 pseudogene 1
ANXA2P2 annexin A2 pseudogene 2
ANXA2P3 annexin A2 pseudogene 3
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOL2 apolipoprotein L, 2
ARF3 ADP-ribosylation factor 3
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ATAD1 ATPase family, AAA domain containing 1
ATAD2 ATPase family, AAA domain containing 2
ATF6B activating transcription factor 6 beta
AUP1 ancient ubiquitous protein 1
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCKDK branched chain ketoacid dehydrogenase kinase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BOLA3 bolA family member 3
BUB3 BUB3 mitotic checkpoint protein
C10ORF54 chromosome 10 open reading frame 54
C10ORF76 chromosome 10 open reading frame 76
C11ORF80 chromosome 11 open reading frame 80
C11ORF84 chromosome 11 open reading frame 84
C2ORF70 chromosome 2 open reading frame 70
C6ORF222 chromosome 6 open reading frame 222
C9ORF91 chromosome 9 open reading frame 91
CACUL1 CDK2-associated, cullin domain 1
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAPG capping protein (actin filament), gelsolin-like
CBFB core-binding factor, beta subunit
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC68 coiled-coil domain containing 68
CCDC9 coiled-coil domain containing 9
CCNA1 cyclin A1
CCNB2 cyclin B2
CCNDBP1 cyclin D-type binding-protein 1
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD82 CD82 molecule
CDC25C cell division cycle 25C
CDC42SE2 CDC42 small effector 2
CDKN2AIPNL CDKN2A interacting protein N-terminal like
CEP19 centrosomal protein 19kDa
CEP55 centrosomal protein 55kDa
CKMT1B creatine kinase, mitochondrial 1B
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLK3 CDC-like kinase 3
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CMTM7 CKLF-like MARVEL transmembrane domain containing 7
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DCTN1 dynactin 1
DEDD2 death effector domain containing 2
DERA deoxyribose-phosphate aldolase (putative)
DERL1 derlin 1
DFNA5 deafness, autosomal dominant 5
DHRS3 dehydrogenase/reductase (SDR family) member 3
DIAPH1 diaphanous-related formin 1
DISP2 dispatched homolog 2 (Drosophila)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
DNASE1L2 deoxyribonuclease I-like 2
DPH6 diphthamine biosynthesis 6
DSCAM Down syndrome cell adhesion molecule
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EFHD2 EF-hand domain family, member D2
EFR3A EFR3 homolog A (S. cerevisiae)
EHD4 EH-domain containing 4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF4H eukaryotic translation initiation factor 4H
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELP4 elongator acetyltransferase complex subunit 4
ERAP2 endoplasmic reticulum aminopeptidase 2
EREG epiregulin
ESYT1 extended synaptotagmin-like protein 1
ETV7 ets variant 7
FAM3C family with sequence similarity 3, member C
FAM45A family with sequence similarity 45, member A
FAM49A family with sequence similarity 49, member A
FAM49B family with sequence similarity 49, member B
FBXL6 F-box and leucine-rich repeat protein 6
FBXO48 F-box protein 48
FNTA farnesyltransferase, CAAX box, alpha
FOXM1 forkhead box M1
FYTTD1 forty-two-three domain containing 1
GALK2 galactokinase 2
GAST gastrin
GBP5 guanylate binding protein 5
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GJB4 gap junction protein, beta 4, 30.3kDa
GLDC glycine dehydrogenase (decarboxylating)
GMPS guanine monphosphate synthase
GPI glucose-6-phosphate isomerase
GRAMD2 GRAM domain containing 2
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRIPAP1 GRIP1 associated protein 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAGH hydroxyacylglutathione hydrolase
HAMP hepcidin antimicrobial peptide
HAP1 huntingtin-associated protein 1
HCAR2 hydroxycarboxylic acid receptor 2
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AD histone cluster 1, H2ad
HIST1H2BG histone cluster 1, H2bg
HIST1H3D histone cluster 1, H3d
HIST1H4I histone cluster 1, H4i
HIST2H2BE histone cluster 2, H2be
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLA-E major histocompatibility complex, class I, E
HMGA1 high mobility group AT-hook 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HN1L hematological and neurological expressed 1-like
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HOOK3 hook microtubule-tethering protein 3
HOXA1 homeobox A1
HOXC13 homeobox C13
HOXC4 homeobox C4
HPS3 Hermansky-Pudlak syndrome 3
HS1BP3 HCLS1 binding protein 3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNE interferon, epsilon
IFT88 intraflagellar transport 88
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGHMBP2 immunoglobulin mu binding protein 2
IL18BP interleukin 18 binding protein
IL7 interleukin 7
IMMT inner membrane protein, mitochondrial
INPPL1 inositol polyphosphate phosphatase-like 1
IRF1 interferon regulatory factor 1
IRF5 interferon regulatory factor 5
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
ITFG2 integrin alpha FG-GAP repeat containing 2
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD11 potassium channel tetramerization domain containing 11
KIAA0226 KIAA0226
KIF18A kinesin family member 18A
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLK4 kallikrein-related peptidase 4
KLK7 kallikrein-related peptidase 7
LCN2 lipocalin 2
LDHA lactate dehydrogenase A
LHX1 LIM homeobox 1
LIMK1 LIM domain kinase 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC100126784 uncharacterized LOC100126784
LOC220729 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) pseudogene
LSM12 LSM12 homolog (S. cerevisiae)
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LSP1 lymphocyte-specific protein 1
MAG myelin associated glycoprotein
MAP2K1 mitogen-activated protein kinase kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MAT2B methionine adenosyltransferase II, beta
MCTP2 multiple C2 domains, transmembrane 2
METTL15 methyltransferase like 15
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MORC3 MORC family CW-type zinc finger 3
MROH6 maestro heat-like repeat family member 6
MRPL10 mitochondrial ribosomal protein L10
MRPL21 mitochondrial ribosomal protein L21
MRPS10 mitochondrial ribosomal protein S10
MSRB1 methionine sulfoxide reductase B1
MTIF2 mitochondrial translational initiation factor 2
MXD1 MAX dimerization protein 1
MYO1C myosin IC
N4BP2L1 NEDD4 binding protein 2-like 1
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NAP1L4 nucleosome assembly protein 1-like 4
NAPRT nicotinate phosphoribosyltransferase
NDRG1 N-myc downstream regulated 1
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NET1 neuroepithelial cell transforming 1
NGFR nerve growth factor receptor
NIPAL4 NIPA-like domain containing 4
NMD3 NMD3 ribosome export adaptor
NOD1 nucleotide-binding oligomerization domain containing 1
NRIP1 nuclear receptor interacting protein 1
NXN nucleoredoxin
NXPH4 neurexophilin 4
OAF OAF homolog (Drosophila)
OPA1 optic atrophy 1 (autosomal dominant)
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene)
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR4E2 olfactory receptor, family 4, subfamily E, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PACS1 phosphofurin acidic cluster sorting protein 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARL presenilin associated, rhomboid-like
PCAT4 prostate cancer associated transcript 4 (non-protein coding)
PCBP1 poly(rC) binding protein 1
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PEX13 peroxisomal biogenesis factor 13
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PKM pyruvate kinase, muscle
PLK1 polo-like kinase 1
PML promyelocytic leukemia
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPA1 pyrophosphatase (inorganic) 1
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PPP6R3 protein phosphatase 6, regulatory subunit 3
PQLC3 PQ loop repeat containing 3
PRICKLE3 prickle homolog 3 (Drosophila)
PRR13 proline rich 13
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTK2B protein tyrosine kinase 2 beta
PTTG2 pituitary tumor-transforming 2
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB19 RAB19, member RAS oncogene family
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
REP15 RAB15 effector protein
RHBDD2 rhomboid domain containing 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIMBP2 RIMS binding protein 2
RMST rhabdomyosarcoma 2 associated transcript (non-protein coding)
RNF170 ring finger protein 170
RPA3 replication protein A3, 14kDa
RRM1 ribonucleotide reductase M1
RRP1B ribosomal RNA processing 1B
RUFY1 RUN and FYVE domain containing 1
SAA1 serum amyloid A1
SCARB1 scavenger receptor class B, member 1
SCARF1 scavenger receptor class F, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC11A SEC11 homolog A (S. cerevisiae)
SELT selenoprotein T
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SF3B6 splicing factor 3b, subunit 6, 14kDa
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SKAP2 src kinase associated phosphoprotein 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A39 solute carrier family 25, member 39
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC39A11 solute carrier family 39, member 11
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SMAD3 SMAD family member 3
SNAI3 snail family zinc finger 3
SNORA61 small nucleolar RNA, H/ACA box 61
SP140 SP140 nuclear body protein
SPATA5L1 spermatogenesis associated 5-like 1
SQRDL sulfide quinone reductase-like (yeast)
SRP68 signal recognition particle 68kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STAG3L2 stromal antigen 3-like 2 (pseudogene)
STAMBP STAM binding protein
STARD3NL STARD3 N-terminal like
STAT1 signal transducer and activator of transcription 1, 91kDa
STEAP2 STEAP family member 2, metalloreductase
STOML1 stomatin (EPB72)-like 1
STRA6 stimulated by retinoic acid 6
STX11 syntaxin 11
STX1B syntaxin 1B
STX6 syntaxin 6
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TARM1 T cell-interacting, activating receptor on myeloid cells 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCOF1 Treacher Collins-Franceschetti syndrome 1
TCTEX1D2 Tctex1 domain containing 2
TFB1M transcription factor B1, mitochondrial
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THADA thyroid adenoma associated
THAP1 THAP domain containing, apoptosis associated protein 1
THEG theg spermatid protein
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
THOC3 THO complex 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMCC3 transmembrane and coiled-coil domain family 3
TMCO6 transmembrane and coiled-coil domains 6
TMEM107 transmembrane protein 107
TMEM214 transmembrane protein 214
TMEM41A transmembrane protein 41A
TMEM51 transmembrane protein 51
TMEM63B transmembrane protein 63B
TMEM95 transmembrane protein 95
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPP1 tripeptidyl peptidase I
TRAF3IP2 TRAF3 interacting protein 2
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRAFD1 TRAF-type zinc finger domain containing 1
TREM1 triggering receptor expressed on myeloid cells 1
TRIM34 tripartite motif containing 34
TSG101 tumor susceptibility 101
TTC31 tetratricopeptide repeat domain 31
TUBG2 tubulin, gamma 2
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
VAMP5 vesicle-associated membrane protein 5
VDAC1 voltage-dependent anion channel 1
WARS tryptophanyl-tRNA synthetase
WBP2 WW domain binding protein 2
WDR54 WD repeat domain 54
YIPF4 Yip1 domain family, member 4
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC16 zinc finger, DHHC-type containing 16
ZMIZ1 zinc finger, MIZ-type containing 1
ZMYND15 zinc finger, MYND-type containing 15
ZNF114 zinc finger protein 114
ZNF318 zinc finger protein 318
ZNF319 zinc finger protein 319
ZNF385A zinc finger protein 385A
ZSWIM2 zinc finger, SWIM-type containing 2

low expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
CARM1 coactivator-associated arginine methyltransferase 1
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EVI5L ecotropic viral integration site 5-like
ZNF20 zinc finger protein 20