HIPK2_knockout_171_GSE39253 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE39253
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Genes

600 genes differentially expressed following the HIPK2_knockout_171_GSE39253 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II 3.18807
BAIAP2 BAI1-associated protein 2 2.87056
HES6 hes family bHLH transcription factor 6 2.83501
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 2.72243
SLIT2 slit homolog 2 (Drosophila) 2.63479
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 2.5861
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.49021
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.47608
LIMS1 LIM and senescent cell antigen-like domains 1 2.35961
STAT5A signal transducer and activator of transcription 5A 2.06889
RAD21 RAD21 homolog (S. pombe) 2.02605
NPTXR neuronal pentraxin receptor 1.96529
PLAGL1 pleiomorphic adenoma gene-like 1 1.75961
MRPS2 mitochondrial ribosomal protein S2 1.69865
LRP12 low density lipoprotein receptor-related protein 12 1.69257
SMAD9 SMAD family member 9 1.66594
ZNF622 zinc finger protein 622 1.65045
JPH3 junctophilin 3 1.63091
GRPEL2 GrpE-like 2, mitochondrial (E. coli) 1.58552
TLL1 tolloid-like 1 1.56804
KIAA0195 KIAA0195 1.51464
DBNL drebrin-like 1.4897
NANOS3 nanos homolog 3 (Drosophila) 1.48266
NPM2 nucleophosmin/nucleoplasmin 2 1.47476
ZNF358 zinc finger protein 358 1.45701
DEF8 differentially expressed in FDCP 8 homolog (mouse) 1.44391
MPDZ multiple PDZ domain protein 1.40657
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.40185
DAPK2 death-associated protein kinase 2 1.39397
TUBGCP3 tubulin, gamma complex associated protein 3 1.36601
ISL2 ISL LIM homeobox 2 1.36483
ART1 ADP-ribosyltransferase 1 1.35219
GSC goosecoid homeobox 1.3518
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.31335
FRZB frizzled-related protein 1.3102
RAD9B RAD9 homolog B (S. pombe) 1.30993
LRRC3 leucine rich repeat containing 3 1.30709
TACR2 tachykinin receptor 2 1.29907
LAPTM5 lysosomal protein transmembrane 5 1.29592
KLF1 Kruppel-like factor 1 (erythroid) 1.29458
ADD2 adducin 2 (beta) 1.29201
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 1.28349
EPHA5 EPH receptor A5 1.27074
DPYSL3 dihydropyrimidinase-like 3 1.25826
RAB33B RAB33B, member RAS oncogene family 1.24376
AURKC aurora kinase C 1.23999
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.20059
UMPS uridine monophosphate synthetase 1.19963
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 1.18403
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.16974
PDCD1LG2 programmed cell death 1 ligand 2 1.16415
VGLL4 vestigial-like family member 4 1.15462
SCG3 secretogranin III 1.14687
GATA1 GATA binding protein 1 (globin transcription factor 1) 1.13356
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.13205
IL12A interleukin 12A 1.13099
SEC24C SEC24 family member C 1.12952
ADAR adenosine deaminase, RNA-specific 1.10151
BMP1 bone morphogenetic protein 1 1.10142
HLA-G major histocompatibility complex, class I, G 1.10132
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 1.10075
RGS12 regulator of G-protein signaling 12 1.09052
RPAP1 RNA polymerase II associated protein 1 1.08464
MRPL10 mitochondrial ribosomal protein L10 1.06203
TMEM14C transmembrane protein 14C 1.05359
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.05142
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.03758
ZNF454 zinc finger protein 454 1.01648
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 1.00745
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.00449
DGKA diacylglycerol kinase, alpha 80kDa 0.992268
ITPKA inositol-trisphosphate 3-kinase A 0.988386
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 0.977985
RFX4 regulatory factor X, 4 (influences HLA class II expression) 0.969922
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.967077
EI24 etoposide induced 2.4 0.96682
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.966088
TMEM2 transmembrane protein 2 0.965349
SYNGR2 synaptogyrin 2 0.959238
OR56A3 olfactory receptor, family 56, subfamily A, member 3 0.946205
TOX thymocyte selection-associated high mobility group box 0.944341
SYNPR synaptoporin 0.943727
IQCB1 IQ motif containing B1 0.940009
EPHA6 EPH receptor A6 0.930228
BARX1 BARX homeobox 1 0.926706
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.921062
PI16 peptidase inhibitor 16 0.915287
METRN meteorin, glial cell differentiation regulator 0.913281
LRRN1 leucine rich repeat neuronal 1 0.906891
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 0.904033
CHN1 chimerin 1 0.899967
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 0.889141
ENAH enabled homolog (Drosophila) 0.882145
APOD apolipoprotein D 0.876466
CNOT4 CCR4-NOT transcription complex, subunit 4 0.87143
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.8712
CHD4 chromodomain helicase DNA binding protein 4 0.870886
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.869281
STRN striatin, calmodulin binding protein 0.853497
NDE1 nudE neurodevelopment protein 1 0.849308
SOSTDC1 sclerostin domain containing 1 0.844733
NUMA1 nuclear mitotic apparatus protein 1 0.841797
COG1 component of oligomeric golgi complex 1 0.835771
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 0.832104
ST18 suppression of tumorigenicity 18, zinc finger 0.828919
ASCL3 achaete-scute family bHLH transcription factor 3 0.828624
LENG8 leukocyte receptor cluster (LRC) member 8 0.827325
PVRL3 poliovirus receptor-related 3 0.826026
SFTPB surfactant protein B 0.817684
C12ORF57 chromosome 12 open reading frame 57 0.814821
UNC5C unc-5 homolog C (C. elegans) 0.811901
FADS2 fatty acid desaturase 2 0.810902
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.809489
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.807504
ZDHHC7 zinc finger, DHHC-type containing 7 0.804824
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.800461
TPX2 TPX2, microtubule-associated 0.797585
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.797065
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.789099
SENP7 SUMO1/sentrin specific peptidase 7 0.786916
GPX7 glutathione peroxidase 7 0.775364
KLF5 Kruppel-like factor 5 (intestinal) 0.772757
EPOR erythropoietin receptor 0.771186
DNMBP dynamin binding protein 0.769503
NLGN1 neuroligin 1 0.769245
PGC progastricsin (pepsinogen C) 0.767419
PRKCSH protein kinase C substrate 80K-H 0.765393
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 0.762611
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.762389
ZNF326 zinc finger protein 326 0.762137
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.759446
ANTXR1 anthrax toxin receptor 1 0.75615
PCP2 Purkinje cell protein 2 0.756078
NXPH4 neurexophilin 4 0.754366
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.753777
ABAT 4-aminobutyrate aminotransferase 0.752445
RACGAP1 Rac GTPase activating protein 1 0.751363
FBXO4 F-box protein 4 0.751325
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.751143
CPXM2 carboxypeptidase X (M14 family), member 2 0.748569
SLC39A11 solute carrier family 39, member 11 0.746502
FRS3 fibroblast growth factor receptor substrate 3 0.742334
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.740124
ITGA11 integrin, alpha 11 0.740044
CKB creatine kinase, brain 0.737191
RAB7B RAB7B, member RAS oncogene family 0.732824
FBXO7 F-box protein 7 0.731359
PDK2 pyruvate dehydrogenase kinase, isozyme 2 0.731086
PON2 paraoxonase 2 0.730469
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 0.727306
VRK3 vaccinia related kinase 3 0.722281
CXXC4 CXXC finger protein 4 0.72228
ATP9A ATPase, class II, type 9A 0.719286
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.719257
BRD8 bromodomain containing 8 0.718558
MEA1 male-enhanced antigen 1 0.718188
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.71453
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 0.709834
ZBTB20 zinc finger and BTB domain containing 20 0.70964
CPOX coproporphyrinogen oxidase 0.709624
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.707097
FIZ1 FLT3-interacting zinc finger 1 0.705456
GJA8 gap junction protein, alpha 8, 50kDa 0.702911
SNAP25 synaptosomal-associated protein, 25kDa 0.702556
BCL7B B-cell CLL/lymphoma 7B 0.70235
MAPRE3 microtubule-associated protein, RP/EB family, member 3 0.696909
MRPL24 mitochondrial ribosomal protein L24 0.695692
SCARF2 scavenger receptor class F, member 2 0.695053
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.694315
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.69373
CNIH2 cornichon family AMPA receptor auxiliary protein 2 0.687559
SEC23B Sec23 homolog B (S. cerevisiae) 0.687069
EGFL6 EGF-like-domain, multiple 6 0.686502
PCNX pecanex homolog (Drosophila) 0.685693
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.6841
SIX2 SIX homeobox 2 0.683824
C21ORF62 chromosome 21 open reading frame 62 0.680917
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.679343
BIVM basic, immunoglobulin-like variable motif containing 0.679145
OR5T2 olfactory receptor, family 5, subfamily T, member 2 0.679143
ACAT1 acetyl-CoA acetyltransferase 1 0.676909
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.675341
CHN2 chimerin 2 0.67467
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.674605
FXYD5 FXYD domain containing ion transport regulator 5 0.672086
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.671918
DMD dystrophin 0.670006
HES5 hes family bHLH transcription factor 5 0.669697
SQRDL sulfide quinone reductase-like (yeast) 0.669114
LAPTM4A lysosomal protein transmembrane 4 alpha 0.668323
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 0.666939
HABP4 hyaluronan binding protein 4 0.663282
TRPS1 trichorhinophalangeal syndrome I 0.661775
ARMCX1 armadillo repeat containing, X-linked 1 0.65878
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.656687
C8ORF4 chromosome 8 open reading frame 4 0.653656
POGZ pogo transposable element with ZNF domain 0.653206
DSG1 desmoglein 1 0.650238
PDCD7 programmed cell death 7 0.649662
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 0.648248
DLX1 distal-less homeobox 1 0.646232
PFN2 profilin 2 0.646001
SNAP91 synaptosomal-associated protein, 91kDa 0.645338
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 0.641994
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.641359
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.639556
IGF1 insulin-like growth factor 1 (somatomedin C) 0.639328
ADGRF1 adhesion G protein-coupled receptor F1 0.638402
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 0.637514
GPSM2 G-protein signaling modulator 2 0.637447
GMPR guanosine monophosphate reductase 0.636485
SPATA1 spermatogenesis associated 1 0.635704
TP63 tumor protein p63 0.635703
GPR50 G protein-coupled receptor 50 0.633285
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.633137
SV2A synaptic vesicle glycoprotein 2A 0.632877
GTF2I general transcription factor IIi 0.631994
OSBPL3 oxysterol binding protein-like 3 0.631613
LENG1 leukocyte receptor cluster (LRC) member 1 0.626618
PBX4 pre-B-cell leukemia homeobox 4 0.625185
BOC BOC cell adhesion associated, oncogene regulated 0.625062
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.624764
CRAT carnitine O-acetyltransferase 0.624712
DNASE2 deoxyribonuclease II, lysosomal 0.622725
SNCAIP synuclein, alpha interacting protein 0.622587
ADAM11 ADAM metallopeptidase domain 11 0.622308
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.622159
KEL Kell blood group, metallo-endopeptidase 0.621836
GPR132 G protein-coupled receptor 132 0.620021
ATF4 activating transcription factor 4 0.61961
REPIN1 replication initiator 1 0.618808
RAB33A RAB33A, member RAS oncogene family 0.61783
EXOSC10 exosome component 10 0.617713
F2RL2 coagulation factor II (thrombin) receptor-like 2 0.617403
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.616474
G6PC glucose-6-phosphatase, catalytic subunit 0.615209
HM13 histocompatibility (minor) 13 0.614698
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.613127
TM4SF1 transmembrane 4 L six family member 1 0.613017
DCX doublecortin 0.611886
IL18BP interleukin 18 binding protein 0.610637
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.607044
RXRG retinoid X receptor, gamma 0.606339
ANAPC13 anaphase promoting complex subunit 13 0.605682
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 0.605301
GPC2 glypican 2 0.603059
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 0.60014
STAU1 staufen double-stranded RNA binding protein 1 0.599736
PTX3 pentraxin 3, long 0.599668
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.598772
CDC25B cell division cycle 25B 0.59831
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.595969
ACTL7A actin-like 7A 0.595147
RPS7 ribosomal protein S7 0.590565
GJB6 gap junction protein, beta 6, 30kDa 0.588836
OSBPL2 oxysterol binding protein-like 2 0.588478
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.588338
DRP2 dystrophin related protein 2 0.588144
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 0.587505
ZNF25 zinc finger protein 25 0.587042
GPR85 G protein-coupled receptor 85 0.586838
DPP6 dipeptidyl-peptidase 6 0.584988
ITPK1 inositol-tetrakisphosphate 1-kinase 0.58422
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.583368
PYCR1 pyrroline-5-carboxylate reductase 1 0.579805
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.579776
ABHD6 abhydrolase domain containing 6 0.579414
FBXL2 F-box and leucine-rich repeat protein 2 0.578533
BTG2 BTG family, member 2 0.578154
DUSP15 dual specificity phosphatase 15 0.577223
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 0.575749
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.574507
TRIM7 tripartite motif containing 7 0.57398
MRPL28 mitochondrial ribosomal protein L28 0.57388
KCTD6 potassium channel tetramerization domain containing 6 0.573639
GMIP GEM interacting protein 0.573631
ING4 inhibitor of growth family, member 4 0.571813
SSTR2 somatostatin receptor 2 0.57068
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.570376
HBZ hemoglobin, zeta 0.570145
ANPEP alanyl (membrane) aminopeptidase 0.569619
C2ORF49 chromosome 2 open reading frame 49 0.56768
C5ORF52 chromosome 5 open reading frame 52 0.566157
TUBB3 tubulin, beta 3 class III 0.566011
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.564089
FSCN2 fascin actin-bundling protein 2, retinal 0.561321
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.561249
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.56119
PCDHA4 protocadherin alpha 4 0.560309
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.55907
OPHN1 oligophrenin 1 0.558516
PIWIL2 piwi-like RNA-mediated gene silencing 2 0.557662
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.557645
WNT10A wingless-type MMTV integration site family, member 10A 0.557042
ZNF318 zinc finger protein 318 0.556237
NSG1 neuron specific gene family member 1 0.556231
KIF5C kinesin family member 5C 0.556159
CUL2 cullin 2 0.555743
CPE carboxypeptidase E 0.554693
AGA aspartylglucosaminidase 0.554467

decreased expression

Symbol Name Standardized Value
AUH AU RNA binding protein/enoyl-CoA hydratase -5.95561
MORF4L2 mortality factor 4 like 2 -2.68504
FBL fibrillarin -2.60279
ARID3B AT rich interactive domain 3B (BRIGHT-like) -2.38674
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.38129
PRKCZ protein kinase C, zeta -2.27101
IL17RE interleukin 17 receptor E -2.13917
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.11329
BRD2 bromodomain containing 2 -2.08096
GORASP2 golgi reassembly stacking protein 2, 55kDa -2.06789
STC2 stanniocalcin 2 -1.99078
MRPL33 mitochondrial ribosomal protein L33 -1.91485
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.90386
PIM3 Pim-3 proto-oncogene, serine/threonine kinase -1.89649
ARMC8 armadillo repeat containing 8 -1.7035
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -1.69125
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -1.6769
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -1.67668
RNF126 ring finger protein 126 -1.64483
CD200R1L CD200 receptor 1-like -1.62589
DMWD dystrophia myotonica, WD repeat containing -1.61928
FGF16 fibroblast growth factor 16 -1.56969
PUS3 pseudouridylate synthase 3 -1.54062
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -1.50765
BAG3 BCL2-associated athanogene 3 -1.49374
C3ORF17 chromosome 3 open reading frame 17 -1.48946
SRPK1 SRSF protein kinase 1 -1.46473
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -1.43258
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 -1.43111
SP1 Sp1 transcription factor -1.42512
C8ORF33 chromosome 8 open reading frame 33 -1.41379
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.40062
SRPR signal recognition particle receptor (docking protein) -1.37365
COG4 component of oligomeric golgi complex 4 -1.37292
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.35714
IFRD2 interferon-related developmental regulator 2 -1.35664
EMB embigin -1.34069
SNX10 sorting nexin 10 -1.33118
KCMF1 potassium channel modulatory factor 1 -1.3279
FOXP3 forkhead box P3 -1.31319
CAPZB capping protein (actin filament) muscle Z-line, beta -1.30073
IL23R interleukin 23 receptor -1.30034
CA4 carbonic anhydrase IV -1.2727
KCNK1 potassium channel, two pore domain subfamily K, member 1 -1.2541
CFDP1 craniofacial development protein 1 -1.25231
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.24043
FBXW8 F-box and WD repeat domain containing 8 -1.23012
OVOL1 ovo-like zinc finger 1 -1.21696
TEK TEK tyrosine kinase, endothelial -1.21293
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -1.21242
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.21225
SRF serum response factor (c-fos serum response element-binding transcription factor) -1.18192
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) -1.18171
ZBTB5 zinc finger and BTB domain containing 5 -1.15994
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.13595
OFD1 oral-facial-digital syndrome 1 -1.12875
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -1.12794
TBRG4 transforming growth factor beta regulator 4 -1.12746
C7ORF50 chromosome 7 open reading frame 50 -1.12599
NET1 neuroepithelial cell transforming 1 -1.1163
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.11609
CD109 CD109 molecule -1.11356
STRAP serine/threonine kinase receptor associated protein -1.10529
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 -1.10176
OR51I2 olfactory receptor, family 51, subfamily I, member 2 -1.09321
TMC6 transmembrane channel-like 6 -1.06171
AMIGO3 adhesion molecule with Ig-like domain 3 -1.05906
HMOX1 heme oxygenase 1 -1.05903
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -1.05781
PAX4 paired box 4 -1.05048
FIGNL1 fidgetin-like 1 -1.04245
CUL4A cullin 4A -1.04048
CCL4 chemokine (C-C motif) ligand 4 -1.0358
ARFRP1 ADP-ribosylation factor related protein 1 -1.03042
EEF1G eukaryotic translation elongation factor 1 gamma -1.02209
CDCA7 cell division cycle associated 7 -1.02003
MRPS11 mitochondrial ribosomal protein S11 -1.01934
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -1.01752
FASN fatty acid synthase -1.00751
EDN1 endothelin 1 -1.00517
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.00144
FBXO31 F-box protein 31 -0.997642
KCTD3 potassium channel tetramerization domain containing 3 -0.997533
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.99172
SNX12 sorting nexin 12 -0.984758
UFD1L ubiquitin fusion degradation 1 like (yeast) -0.978716
RCN1 reticulocalbin 1, EF-hand calcium binding domain -0.97783
MED19 mediator complex subunit 19 -0.974292
RPN1 ribophorin I -0.972943
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -0.970594
GRHPR glyoxylate reductase/hydroxypyruvate reductase -0.969836
RABGGTA Rab geranylgeranyltransferase, alpha subunit -0.96882
PRPF4 pre-mRNA processing factor 4 -0.959871
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -0.951652
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.948688
TOM1 target of myb1 (chicken) -0.946499
H2AFZ H2A histone family, member Z -0.946264
KIF5B kinesin family member 5B -0.943935
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 -0.933493
CARD10 caspase recruitment domain family, member 10 -0.924637
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -0.91699
C7ORF31 chromosome 7 open reading frame 31 -0.916124
TWIST1 twist family bHLH transcription factor 1 -0.914442
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.913099
FOXB1 forkhead box B1 -0.906296
VAMP3 vesicle-associated membrane protein 3 -0.905596
PARK7 parkinson protein 7 -0.902161
RPS26 ribosomal protein S26 -0.899977
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.898981
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -0.895027
PRIMA1 proline rich membrane anchor 1 -0.891052
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.889253
ILK integrin-linked kinase -0.886729
ANTXR2 anthrax toxin receptor 2 -0.881029
MTSS1 metastasis suppressor 1 -0.877348
SIN3A SIN3 transcription regulator family member A -0.875999
ICA1 islet cell autoantigen 1, 69kDa -0.870033
MSH2 mutS homolog 2 -0.865796
LAG3 lymphocyte-activation gene 3 -0.860696
USP3 ubiquitin specific peptidase 3 -0.859858
L3MBTL3 l(3)mbt-like 3 (Drosophila) -0.858448
NKX2-3 NK2 homeobox 3 -0.855777
VAMP5 vesicle-associated membrane protein 5 -0.855632
FEN1 flap structure-specific endonuclease 1 -0.854489
HIPK2 homeodomain interacting protein kinase 2 -0.853837
WASF3 WAS protein family, member 3 -0.849817
SLAMF7 SLAM family member 7 -0.846164
PRSS16 protease, serine, 16 (thymus) -0.843656
JUNB jun B proto-oncogene -0.840789
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -0.837102
BRI3 brain protein I3 -0.834551
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -0.831464
TRIM27 tripartite motif containing 27 -0.830918
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -0.828938
TSNAX translin-associated factor X -0.828695
P3H2 prolyl 3-hydroxylase 2 -0.828611
BCAS2 breast carcinoma amplified sequence 2 -0.826844
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase -0.826262
PKP4 plakophilin 4 -0.820874
CDC6 cell division cycle 6 -0.820766
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.813902
COL18A1 collagen, type XVIII, alpha 1 -0.811712
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -0.808619
EGFL8 EGF-like-domain, multiple 8 -0.807151
GLI3 GLI family zinc finger 3 -0.806643
RHOB ras homolog family member B -0.804706
BASP1 brain abundant, membrane attached signal protein 1 -0.804624
C14ORF169 chromosome 14 open reading frame 169 -0.803364
ZNF226 zinc finger protein 226 -0.803221
FBXO22 F-box protein 22 -0.801737
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.796994
TUBB tubulin, beta class I -0.796226
RAB5A RAB5A, member RAS oncogene family -0.795874
GRB2 growth factor receptor-bound protein 2 -0.79416
TEX9 testis expressed 9 -0.793229
IER2 immediate early response 2 -0.792713
APRT adenine phosphoribosyltransferase -0.790296
ALG12 ALG12, alpha-1,6-mannosyltransferase -0.784037
F2RL3 coagulation factor II (thrombin) receptor-like 3 -0.783598
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.782756
RPL3 ribosomal protein L3 -0.782219
MRPL18 mitochondrial ribosomal protein L18 -0.782078
ZNF565 zinc finger protein 565 -0.781536
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.781273
ADSL adenylosuccinate lyase -0.779584
CCR4 chemokine (C-C motif) receptor 4 -0.779271
VEGFB vascular endothelial growth factor B -0.769182
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -0.767285
SSR4 signal sequence receptor, delta -0.765615
MTMR4 myotubularin related protein 4 -0.765196
ADAM32 ADAM metallopeptidase domain 32 -0.76368
LMO2 LIM domain only 2 (rhombotin-like 1) -0.763235
SRL sarcalumenin -0.76296
DLX5 distal-less homeobox 5 -0.761997
RPL38 ribosomal protein L38 -0.760299
HSPA14 heat shock 70kDa protein 14 -0.755663
COL13A1 collagen, type XIII, alpha 1 -0.752624
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.752242
APC adenomatous polyposis coli -0.752105
PCSK2 proprotein convertase subtilisin/kexin type 2 -0.751221
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.751131
KCNK12 potassium channel, two pore domain subfamily K, member 12 -0.749678
RNF31 ring finger protein 31 -0.74897
ZNF574 zinc finger protein 574 -0.748586
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -0.747823
IL6ST interleukin 6 signal transducer -0.744148
ADA adenosine deaminase -0.742906
XRN2 5'-3' exoribonuclease 2 -0.741367
SAV1 salvador family WW domain containing protein 1 -0.740114
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.738674
NUP155 nucleoporin 155kDa -0.738568
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -0.738228
VASP vasodilator-stimulated phosphoprotein -0.738214
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -0.73774
NTAN1 N-terminal asparagine amidase -0.737725
SOCS4 suppressor of cytokine signaling 4 -0.73635
USF2 upstream transcription factor 2, c-fos interacting -0.735451
LIG1 ligase I, DNA, ATP-dependent -0.734976
SERTAD3 SERTA domain containing 3 -0.733431
CYLD cylindromatosis (turban tumor syndrome) -0.732926
RAE1 ribonucleic acid export 1 -0.730922
STARD10 StAR-related lipid transfer (START) domain containing 10 -0.730421
SPATA5 spermatogenesis associated 5 -0.72707
PHB prohibitin -0.727021
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.725951
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -0.724845
GRIK5 glutamate receptor, ionotropic, kainate 5 -0.72441
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.724331
MCM6 minichromosome maintenance complex component 6 -0.723993
ECE1 endothelin converting enzyme 1 -0.723967
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -0.723833
COASY CoA synthase -0.723243
PDGFA platelet-derived growth factor alpha polypeptide -0.722514
C12ORF66 chromosome 12 open reading frame 66 -0.719462
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.718967
TXNIP thioredoxin interacting protein -0.718152
RPL18 ribosomal protein L18 -0.71715
SLBP stem-loop binding protein -0.717092
AGER advanced glycosylation end product-specific receptor -0.715959
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -0.714012
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.712031
DGUOK deoxyguanosine kinase -0.711959
FPGS folylpolyglutamate synthase -0.709361
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 -0.707621
AMOTL2 angiomotin like 2 -0.706136
TRUB2 TruB pseudouridine (psi) synthase family member 2 -0.705711
TTC19 tetratricopeptide repeat domain 19 -0.704903
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -0.704567
IPO11 importin 11 -0.702822
ZNF665 zinc finger protein 665 -0.70282
PDCD2 programmed cell death 2 -0.700085
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 -0.69995
WBP11 WW domain binding protein 11 -0.697663
SESN2 sestrin 2 -0.697068
NDNL2 necdin-like 2 -0.697031
SDHAF4 succinate dehydrogenase complex assembly factor 4 -0.695992
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -0.695634
LMO4 LIM domain only 4 -0.695314
SDF2L1 stromal cell-derived factor 2-like 1 -0.694568
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -0.69395
GEMIN5 gem (nuclear organelle) associated protein 5 -0.693424
TLE2 transducin-like enhancer of split 2 -0.689723
ELAC2 elaC ribonuclease Z 2 -0.689614
GKAP1 G kinase anchoring protein 1 -0.688979
RASGEF1B RasGEF domain family, member 1B -0.688002
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 -0.687963
RPS29 ribosomal protein S29 -0.687635
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.68376
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -0.683409
GPRC5C G protein-coupled receptor, class C, group 5, member C -0.683293
NGB neuroglobin -0.682779
CD63 CD63 molecule -0.681445
HPS6 Hermansky-Pudlak syndrome 6 -0.680537
UXS1 UDP-glucuronate decarboxylase 1 -0.679909
TPST1 tyrosylprotein sulfotransferase 1 -0.679808
FBXO46 F-box protein 46 -0.676012
MIB1 mindbomb E3 ubiquitin protein ligase 1 -0.675615
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -0.674525
MRPS22 mitochondrial ribosomal protein S22 -0.6741
UBE2M ubiquitin-conjugating enzyme E2M -0.67384
COPS8 COP9 signalosome subunit 8 -0.67133
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -0.669504
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -0.669163
DICER1 dicer 1, ribonuclease type III -0.669079
M6PR mannose-6-phosphate receptor (cation dependent) -0.667471
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -0.666872
TERF2IP telomeric repeat binding factor 2, interacting protein -0.665456
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -0.661526
TK1 thymidine kinase 1, soluble -0.658943
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -0.656228
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.656025
SOD1 superoxide dismutase 1, soluble -0.655997
TRIM28 tripartite motif containing 28 -0.65579
SLURP1 secreted LY6/PLAUR domain containing 1 -0.653372
MUM1L1 melanoma associated antigen (mutated) 1-like 1 -0.652956
MAPK3 mitogen-activated protein kinase 3 -0.651742
PTDSS2 phosphatidylserine synthase 2 -0.651503
KIAA0020 KIAA0020 -0.650793
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.649069
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.64897
MRPS28 mitochondrial ribosomal protein S28 -0.648523
COMMD4 COMM domain containing 4 -0.647328
IRX4 iroquois homeobox 4 -0.645233
PLS3 plastin 3 -0.644259
SCAMP3 secretory carrier membrane protein 3 -0.64099
RXRB retinoid X receptor, beta -0.639099
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.637989
EFHD2 EF-hand domain family, member D2 -0.636745
OR11H6 olfactory receptor, family 11, subfamily H, member 6 -0.634149
QDPR quinoid dihydropteridine reductase -0.633855
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -0.633806
COQ6 coenzyme Q6 monooxygenase -0.633693
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.633463
ODC1 ornithine decarboxylase 1 -0.632641
RPS3 ribosomal protein S3 -0.631346
MMD monocyte to macrophage differentiation-associated -0.630788
ANAPC1 anaphase promoting complex subunit 1 -0.63076
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 -0.630512
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.629461
RHO rhodopsin -0.629149