HIPK2_knockdown_106_GSE27869 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27869
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Genes

600 genes differentially expressed following the HIPK2_knockdown_106_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.74117
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.63914
TLDC1 TBC/LysM-associated domain containing 1 2.61289
CCT7 chaperonin containing TCP1, subunit 7 (eta) 2.49518
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 2.46327
TSKS testis-specific serine kinase substrate 2.39306
MPZL1 myelin protein zero-like 1 2.3352
HIST1H2BJ histone cluster 1, H2bj 2.33496
RPS27 ribosomal protein S27 2.3316
FAHD1 fumarylacetoacetate hydrolase domain containing 1 2.3295
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 2.31558
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 2.28378
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 2.1801
TBRG1 transforming growth factor beta regulator 1 2.17499
ENOX2 ecto-NOX disulfide-thiol exchanger 2 2.17382
IL6 interleukin 6 2.1549
EIF3D eukaryotic translation initiation factor 3, subunit D 2.12593
COQ10A coenzyme Q10 homolog A (S. cerevisiae) 2.12519
RAB4B RAB4B, member RAS oncogene family 2.12198
FDX1 ferredoxin 1 2.11439
DTWD1 DTW domain containing 1 2.10956
NTN3 netrin 3 2.10797
RBM12 RNA binding motif protein 12 2.10783
EMC4 ER membrane protein complex subunit 4 2.10355
NEK6 NIMA-related kinase 6 2.0997
TMEM51 transmembrane protein 51 2.09923
INPP1 inositol polyphosphate-1-phosphatase 2.0944
SCAND2P SCAN domain containing 2 pseudogene 2.09048
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 2.08604
MTCH1 mitochondrial carrier 1 2.08491
VIMP VCP-interacting membrane selenoprotein 2.07981
MRPL40 mitochondrial ribosomal protein L40 2.07598
MKRN1 makorin ring finger protein 1 2.07457
CDC42 cell division cycle 42 2.07202
HIST3H2A histone cluster 3, H2a 2.06803
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2.06773
SRD5A3 steroid 5 alpha-reductase 3 2.0571
SDCCAG3 serologically defined colon cancer antigen 3 2.04729
DCAF13 DDB1 and CUL4 associated factor 13 2.04077
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 2.03968
AAGAB alpha- and gamma-adaptin binding protein 2.03912
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 2.0387
ABLIM3 actin binding LIM protein family, member 3 2.03799
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.02356
SIN3A SIN3 transcription regulator family member A 2.0057
MTFR1L mitochondrial fission regulator 1-like 2.00424
CLN5 ceroid-lipofuscinosis, neuronal 5 2.00409
ERMARD ER membrane-associated RNA degradation 2.00253
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.00229
EEF1B2 eukaryotic translation elongation factor 1 beta 2 1.9915
TONSL tonsoku-like, DNA repair protein 1.98096
AQP10 aquaporin 10 1.9793
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.97133
PGS1 phosphatidylglycerophosphate synthase 1 1.9614
HYI hydroxypyruvate isomerase (putative) 1.95786
RNF166 ring finger protein 166 1.95694
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1.95627
PON2 paraoxonase 2 1.94959
HDLBP high density lipoprotein binding protein 1.91685
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 1.91584
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 1.90647
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.90464
HSPA8 heat shock 70kDa protein 8 1.89288
UBAP2L ubiquitin associated protein 2-like 1.89242
ERCC4 excision repair cross-complementation group 4 1.88912
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 1.88681
IFT43 intraflagellar transport 43 1.88621
CAMLG calcium modulating ligand 1.88314
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 1.87945
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 1.87536
NUB1 negative regulator of ubiquitin-like proteins 1 1.87192
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.87119
ZC3H10 zinc finger CCCH-type containing 10 1.87054
HSF4 heat shock transcription factor 4 1.86728
FGD5-AS1 FGD5 antisense RNA 1 1.86579
VANGL1 VANGL planar cell polarity protein 1 1.84307
LSM1 LSM1, U6 small nuclear RNA associated 1.84263
ATCAY ataxia, cerebellar, Cayman type 1.84162
ZXDB zinc finger, X-linked, duplicated B 1.83564
TMEM177 transmembrane protein 177 1.83201
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.83134
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 1.8312
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.82977
ANAPC5 anaphase promoting complex subunit 5 1.82963
TSPAN3 tetraspanin 3 1.82803
PGBD1 piggyBac transposable element derived 1 1.82785
HMOX2 heme oxygenase 2 1.82354
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.82089
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 1.81736
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1.81592
EFNA3 ephrin-A3 1.81358
DCTN6 dynactin 6 1.80951
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 1.8065
NR2C2 nuclear receptor subfamily 2, group C, member 2 1.80586
METTL13 methyltransferase like 13 1.80533
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1.80518
SRXN1 sulfiredoxin 1 1.80218
TM2D2 TM2 domain containing 2 1.79941
PLRG1 pleiotropic regulator 1 1.79934
TMEM68 transmembrane protein 68 1.79922
DYNLRB1 dynein, light chain, roadblock-type 1 1.79777
FBXO5 F-box protein 5 1.79724
TXN2 thioredoxin 2 1.79349
ACP2 acid phosphatase 2, lysosomal 1.79294
TMEM242 transmembrane protein 242 1.79237
PPP1R17 protein phosphatase 1, regulatory subunit 17 1.78915
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 1.78648
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.7788
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 1.77824
ETNK1 ethanolamine kinase 1 1.77601
DRAM1 DNA-damage regulated autophagy modulator 1 1.77053
GOPC golgi-associated PDZ and coiled-coil motif containing 1.76844
TMEM53 transmembrane protein 53 1.76613
TMEM216 transmembrane protein 216 1.76505
WDR18 WD repeat domain 18 1.76315
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.76226
RANBP10 RAN binding protein 10 1.76026
C8ORF76 chromosome 8 open reading frame 76 1.75933
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 1.75641
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.74981
PUS3 pseudouridylate synthase 3 1.7497
ZNF587 zinc finger protein 587 1.74673
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 1.74264
PDCD2L programmed cell death 2-like 1.74209
SURF2 surfeit 2 1.74057
ZC3H15 zinc finger CCCH-type containing 15 1.74052
AXIN2 axin 2 1.73972
DNAH1 dynein, axonemal, heavy chain 1 1.73715
HSPA14 heat shock 70kDa protein 14 1.7352
PRCC papillary renal cell carcinoma (translocation-associated) 1.73379
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.73197
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 1.73132
ZFAND1 zinc finger, AN1-type domain 1 1.72674
PRPF3 pre-mRNA processing factor 3 1.72639
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.72509
CHML choroideremia-like (Rab escort protein 2) 1.72221
LSG1 large 60S subunit nuclear export GTPase 1 1.72104
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 1.72094
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 1.72004
BBS4 Bardet-Biedl syndrome 4 1.71659
HEBP1 heme binding protein 1 1.71551
INTS4 integrator complex subunit 4 1.71537
TMEM185B transmembrane protein 185B 1.71458
STX2 syntaxin 2 1.71323
TMEM186 transmembrane protein 186 1.71035
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 1.70986
MEAF6 MYST/Esa1-associated factor 6 1.70855
CSNK1E casein kinase 1, epsilon 1.70765
PEF1 penta-EF-hand domain containing 1 1.7068
MPND MPN domain containing 1.70663
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.70571
RTFDC1 replication termination factor 2 domain containing 1 1.70501
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 1.7048
RAB31 RAB31, member RAS oncogene family 1.70132
RBMXL1 RNA binding motif protein, X-linked-like 1 1.69698
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 1.69542
FAM13B family with sequence similarity 13, member B 1.69539
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.69198
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.6873
METTL4 methyltransferase like 4 1.68553
CABS1 calcium-binding protein, spermatid-specific 1 1.6849
TMEM143 transmembrane protein 143 1.68159
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 1.68147
STAT5A signal transducer and activator of transcription 5A 1.6772
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 1.67615
MEMO1 mediator of cell motility 1 1.67611
DDT D-dopachrome tautomerase 1.67419
KIAA2026 KIAA2026 1.67219
WDR74 WD repeat domain 74 1.67002
ASXL1 additional sex combs like transcriptional regulator 1 1.66929
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.66741
PCDHGC5 protocadherin gamma subfamily C, 5 1.66549
E2F6 E2F transcription factor 6 1.6635
EMC6 ER membrane protein complex subunit 6 1.66325
HIST1H2BC histone cluster 1, H2bc 1.66224
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 1.66081
TTC31 tetratricopeptide repeat domain 31 1.65572
CTPS1 CTP synthase 1 1.65564
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.65558
NAT10 N-acetyltransferase 10 (GCN5-related) 1.65521
LSMEM1 leucine-rich single-pass membrane protein 1 1.65314
ZNF668 zinc finger protein 668 1.65301
NBR1 neighbor of BRCA1 gene 1 1.65029
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 1.64884
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) 1.64847
FGF2 fibroblast growth factor 2 (basic) 1.64424
NFS1 NFS1 cysteine desulfurase 1.64363
RPS12 ribosomal protein S12 1.64233
FOSL2 FOS-like antigen 2 1.64192
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1.63837
VAMP4 vesicle-associated membrane protein 4 1.63836
YIPF1 Yip1 domain family, member 1 1.63793
RLIM ring finger protein, LIM domain interacting 1.63518
RPP21 ribonuclease P/MRP 21kDa subunit 1.63405
RARS arginyl-tRNA synthetase 1.63334
OSBPL2 oxysterol binding protein-like 2 1.63316
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.62871
RAB14 RAB14, member RAS oncogene family 1.62861
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.62822
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.62459
MAP7D3 MAP7 domain containing 3 1.62064
PRSS33 protease, serine, 33 1.61867
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 1.61723
CD59 CD59 molecule, complement regulatory protein 1.61593
GIMAP4 GTPase, IMAP family member 4 1.61479
C1QBP complement component 1, q subcomponent binding protein 1.61364
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.61289
MYO19 myosin XIX 1.61262
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.60901
SOX8 SRY (sex determining region Y)-box 8 1.60873
ZNF397 zinc finger protein 397 1.60837
SAR1B secretion associated, Ras related GTPase 1B 1.60831
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1.60789
C3ORF36 chromosome 3 open reading frame 36 1.60509
C9ORF156 chromosome 9 open reading frame 156 1.60244
C18ORF32 chromosome 18 open reading frame 32 1.60146
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.59838
TRAPPC3 trafficking protein particle complex 3 1.59823
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 1.59491
GSTK1 glutathione S-transferase kappa 1 1.59324
VCP valosin containing protein 1.593
JAM3 junctional adhesion molecule 3 1.59035
RPL18A ribosomal protein L18a 1.589
CCDC88A coiled-coil domain containing 88A 1.58851
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.58846
GCFC2 GC-rich sequence DNA-binding factor 2 1.58832
IFT172 intraflagellar transport 172 1.58802
UBE2K ubiquitin-conjugating enzyme E2K 1.58731
UBE2H ubiquitin-conjugating enzyme E2H 1.58384
YAP1 Yes-associated protein 1 1.58382
NUP160 nucleoporin 160kDa 1.58326
B9D1 B9 protein domain 1 1.58272
BMX BMX non-receptor tyrosine kinase 1.57956
TSNAX translin-associated factor X 1.57773
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.5766
HIST1H3H histone cluster 1, H3h 1.57517
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1.57486
PRPS1 phosphoribosyl pyrophosphate synthetase 1 1.57133
SNX9 sorting nexin 9 1.57115
AMOT angiomotin 1.57053
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) 1.56705
LOC286272 uncharacterized LOC286272 1.56634
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.56566
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B 1.56508
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.56439
GMEB2 glucocorticoid modulatory element binding protein 2 1.56244
ZFYVE9 zinc finger, FYVE domain containing 9 1.55943
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 1.55885
PLA2G12A phospholipase A2, group XIIA 1.55857
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 1.55706
SAP30BP SAP30 binding protein 1.55679
C7ORF25 chromosome 7 open reading frame 25 1.55513
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.55256
ZSCAN5A zinc finger and SCAN domain containing 5A 1.55093
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 1.55017
OTUD4 OTU deubiquitinase 4 1.54876
TGOLN2 trans-golgi network protein 2 1.54828
CYTH1 cytohesin 1 1.54795
PRR14 proline rich 14 1.5473
ARMC7 armadillo repeat containing 7 1.5447
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 1.54426
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 1.54371
SPIN1 spindlin 1 1.54363
BMP2K BMP2 inducible kinase 1.54306
TMEM237 transmembrane protein 237 1.54287
CCDC121 coiled-coil domain containing 121 1.54026
AGK acylglycerol kinase 1.53811
MFSD8 major facilitator superfamily domain containing 8 1.53059
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.52874
TMSB10 thymosin beta 10 1.52827
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.52662
RHOA ras homolog family member A 1.52615
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.52609
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 1.52423
RPL38 ribosomal protein L38 1.52376
JADE1 jade family PHD finger 1 1.52199
EBPL emopamil binding protein-like 1.52198
TMEM261 transmembrane protein 261 1.51871
MAPK9 mitogen-activated protein kinase 9 1.51818
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.51811
ORC4 origin recognition complex, subunit 4 1.51429
VTN vitronectin 1.51292
THEM4 thioesterase superfamily member 4 1.51227
PRR13 proline rich 13 1.51206
DAPK1 death-associated protein kinase 1 1.51066
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 1.50686
MRPS14 mitochondrial ribosomal protein S14 1.50684
RPS13 ribosomal protein S13 1.50424
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.50243
ZSWIM6 zinc finger, SWIM-type containing 6 1.50201
REXO2 RNA exonuclease 2 1.50054
ACHE acetylcholinesterase (Yt blood group) 1.49947
VAC14 Vac14 homolog (S. cerevisiae) 1.49605
LCMT2 leucine carboxyl methyltransferase 2 1.49259
RHOQ ras homolog family member Q 1.4915
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 1.48748
GOSR2 golgi SNAP receptor complex member 2 1.48731
INSIG2 insulin induced gene 2 1.48673
TTYH2 tweety family member 2 1.48655
ZNF581 zinc finger protein 581 1.48595

decreased expression

Symbol Name Standardized Value
EMC8 ER membrane protein complex subunit 8 -4.1797
BRD1 bromodomain containing 1 -3.70899
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -3.70407
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -3.63728
MED4 mediator complex subunit 4 -3.38526
GPANK1 G patch domain and ankyrin repeats 1 -3.34908
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -3.28144
PCNP PEST proteolytic signal containing nuclear protein -3.18897
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.18753
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -3.15361
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -3.14192
DENR density-regulated protein -3.13265
SRSF9 serine/arginine-rich splicing factor 9 -3.10172
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.91048
INHBE inhibin, beta E -2.89239
SEC62 SEC62 homolog (S. cerevisiae) -2.88386
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -2.87839
ZNF585A zinc finger protein 585A -2.84372
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.83765
TPM1 tropomyosin 1 (alpha) -2.83216
FN1 fibronectin 1 -2.81987
OTUD5 OTU deubiquitinase 5 -2.77855
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -2.75721
LEMD3 LEM domain containing 3 -2.74623
EID1 EP300 interacting inhibitor of differentiation 1 -2.72798
PICK1 protein interacting with PRKCA 1 -2.71444
GIGYF1 GRB10 interacting GYF protein 1 -2.68187
PSEN1 presenilin 1 -2.67206
GOLM1 golgi membrane protein 1 -2.66029
HIPK2 homeodomain interacting protein kinase 2 -2.62599
S100A7 S100 calcium binding protein A7 -2.55842
MRPL3 mitochondrial ribosomal protein L3 -2.53986
GLUL glutamate-ammonia ligase -2.5032
IRS4 insulin receptor substrate 4 -2.50221
ADO 2-aminoethanethiol (cysteamine) dioxygenase -2.47905
MIS12 MIS12 kinetochore complex component -2.47789
S100A6 S100 calcium binding protein A6 -2.46833
UEVLD UEV and lactate/malate dehyrogenase domains -2.45241
METTL18 methyltransferase like 18 -2.42022
ACBD5 acyl-CoA binding domain containing 5 -2.41686
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -2.41406
TDG thymine-DNA glycosylase -2.40513
OXSR1 oxidative stress responsive 1 -2.38426
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.37868
FECH ferrochelatase -2.35999
HTRA1 HtrA serine peptidase 1 -2.35012
GPR55 G protein-coupled receptor 55 -2.33734
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.33646
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -2.33176
C20ORF24 chromosome 20 open reading frame 24 -2.32554
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.32193
RGS19 regulator of G-protein signaling 19 -2.32141
ZNF35 zinc finger protein 35 -2.29794
SLC25A42 solute carrier family 25, member 42 -2.29437
IGBP1 immunoglobulin (CD79A) binding protein 1 -2.28864
LRRC8D leucine rich repeat containing 8 family, member D -2.28787
NMT2 N-myristoyltransferase 2 -2.26912
MOSPD1 motile sperm domain containing 1 -2.26398
MBIP MAP3K12 binding inhibitory protein 1 -2.25812
FSTL1 follistatin-like 1 -2.25438
SCRN3 secernin 3 -2.24232
SMAP1 small ArfGAP 1 -2.23525
RWDD3 RWD domain containing 3 -2.2298
NADK2 NAD kinase 2, mitochondrial -2.2255
KNSTRN kinetochore-localized astrin/SPAG5 binding protein -2.21493
ELOVL5 ELOVL fatty acid elongase 5 -2.20867
TFAM transcription factor A, mitochondrial -2.20404
ASB3 ankyrin repeat and SOCS box containing 3 -2.19769
LOC158402 uncharacterized LOC158402 -2.17995
RSU1 Ras suppressor protein 1 -2.16519
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -2.16467
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -2.16266
SETD7 SET domain containing (lysine methyltransferase) 7 -2.15325
USP28 ubiquitin specific peptidase 28 -2.13703
RGS3 regulator of G-protein signaling 3 -2.12389
TTLL12 tubulin tyrosine ligase-like family member 12 -2.09821
HP1BP3 heterochromatin protein 1, binding protein 3 -2.0978
CDCA4 cell division cycle associated 4 -2.09013
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 -2.08243
KCTD10 potassium channel tetramerization domain containing 10 -2.08191
TCEAL8 transcription elongation factor A (SII)-like 8 -2.07928
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -2.07835
NCOA4 nuclear receptor coactivator 4 -2.07198
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -2.06995
PRMT6 protein arginine methyltransferase 6 -2.06717
MOCS2 molybdenum cofactor synthesis 2 -2.05509
ZNF268 zinc finger protein 268 -2.04462
WDR37 WD repeat domain 37 -2.03316
METAP1D methionyl aminopeptidase type 1D (mitochondrial) -2.03246
RBPJ recombination signal binding protein for immunoglobulin kappa J region -2.03043
EXT1 exostosin glycosyltransferase 1 -2.02868
ZNF124 zinc finger protein 124 -2.0231
C1ORF131 chromosome 1 open reading frame 131 -2.01915
DCAF8 DDB1 and CUL4 associated factor 8 -2.01491
ANKRD12 ankyrin repeat domain 12 -2.00661
MSL1 male-specific lethal 1 homolog (Drosophila) -1.99711
ERCC8 excision repair cross-complementation group 8 -1.99355
DCAF7 DDB1 and CUL4 associated factor 7 -1.99305
DLG4 discs, large homolog 4 (Drosophila) -1.99121
PHC3 polyhomeotic homolog 3 (Drosophila) -1.99054
SVIL supervillin -1.98758
MED7 mediator complex subunit 7 -1.98095
C6ORF203 chromosome 6 open reading frame 203 -1.98013
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.97896
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 -1.97872
DENND3 DENN/MADD domain containing 3 -1.97849
EDF1 endothelial differentiation-related factor 1 -1.97844
ZNF24 zinc finger protein 24 -1.9679
PCGF5 polycomb group ring finger 5 -1.96488
CRYZ crystallin, zeta (quinone reductase) -1.96356
NUMB numb homolog (Drosophila) -1.95443
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -1.95411
PRKCD protein kinase C, delta -1.95062
HNRNPR heterogeneous nuclear ribonucleoprotein R -1.94937
UBE2M ubiquitin-conjugating enzyme E2M -1.94683
CBFB core-binding factor, beta subunit -1.94351
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -1.94191
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -1.94096
GAL galanin/GMAP prepropeptide -1.93453
SYPL1 synaptophysin-like 1 -1.9329
WRB tryptophan rich basic protein -1.93195
MON1A MON1 secretory trafficking family member A -1.92998
BRWD1 bromodomain and WD repeat domain containing 1 -1.91423
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 -1.91137
TUBGCP4 tubulin, gamma complex associated protein 4 -1.90927
FBXO21 F-box protein 21 -1.90788
MLF2 myeloid leukemia factor 2 -1.8997
SETD8 SET domain containing (lysine methyltransferase) 8 -1.89917
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -1.89619
BCL6 B-cell CLL/lymphoma 6 -1.88977
C1ORF115 chromosome 1 open reading frame 115 -1.88494
GK glycerol kinase -1.88425
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -1.87834
SPEF2 sperm flagellar 2 -1.87777
GPN3 GPN-loop GTPase 3 -1.87742
CDKL3 cyclin-dependent kinase-like 3 -1.87349
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -1.87343
DIRC2 disrupted in renal carcinoma 2 -1.86939
CHUK conserved helix-loop-helix ubiquitous kinase -1.8656
OLFM1 olfactomedin 1 -1.86502
GPR176 G protein-coupled receptor 176 -1.86483
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -1.86112
PAX9 paired box 9 -1.85712
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -1.85394
SNX2 sorting nexin 2 -1.85131
PECR peroxisomal trans-2-enoyl-CoA reductase -1.85034
DCLRE1A DNA cross-link repair 1A -1.84473
FAM120B family with sequence similarity 120B -1.84421
FJX1 four jointed box 1 (Drosophila) -1.84368
USP10 ubiquitin specific peptidase 10 -1.83592
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -1.8359
TMED3 transmembrane emp24 protein transport domain containing 3 -1.83077
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -1.82746
COMMD1 copper metabolism (Murr1) domain containing 1 -1.82537
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -1.82369
KANSL1L KAT8 regulatory NSL complex subunit 1-like -1.81849
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 -1.81482
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -1.81201
GPR107 G protein-coupled receptor 107 -1.80759
KIN Kin17 DNA and RNA binding protein -1.80703
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -1.8038
ZNF740 zinc finger protein 740 -1.80256
FUNDC2 FUN14 domain containing 2 -1.79992
RSRC1 arginine/serine-rich coiled-coil 1 -1.79698
MBD4 methyl-CpG binding domain protein 4 -1.79574
POGK pogo transposable element with KRAB domain -1.79379
TTLL7 tubulin tyrosine ligase-like family member 7 -1.7928
BFAR bifunctional apoptosis regulator -1.79074
ARHGAP18 Rho GTPase activating protein 18 -1.78788
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -1.78746
BRD2 bromodomain containing 2 -1.78635
RPS3 ribosomal protein S3 -1.78158
TMEM30A transmembrane protein 30A -1.78021
INTS6 integrator complex subunit 6 -1.77482
CCNE1 cyclin E1 -1.76948
TROVE2 TROVE domain family, member 2 -1.76671
MTX2 metaxin 2 -1.7649
EPB41 erythrocyte membrane protein band 4.1 -1.76176
PCSK1 proprotein convertase subtilisin/kexin type 1 -1.7614
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -1.75328
HSPB8 heat shock 22kDa protein 8 -1.74776
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -1.74761
RAB2A RAB2A, member RAS oncogene family -1.74747
ASF1A anti-silencing function 1A histone chaperone -1.74705
SLIRP SRA stem-loop interacting RNA binding protein -1.74507
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 -1.73318
FAM122B family with sequence similarity 122B -1.72452
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -1.7217
SKA2 spindle and kinetochore associated complex subunit 2 -1.7213
WDR77 WD repeat domain 77 -1.72061
MED29 mediator complex subunit 29 -1.71937
RBBP4 retinoblastoma binding protein 4 -1.71621
ARMC8 armadillo repeat containing 8 -1.71551
COPS7A COP9 signalosome subunit 7A -1.70898
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 -1.70512
UFSP2 UFM1-specific peptidase 2 -1.70323
NENF neudesin neurotrophic factor -1.69969
GPR83 G protein-coupled receptor 83 -1.69668
KRT31 keratin 31, type I -1.69311
MESDC1 mesoderm development candidate 1 -1.69241
CYTH3 cytohesin 3 -1.69199
CENPH centromere protein H -1.69108
LINC00599 long intergenic non-protein coding RNA 599 -1.68722
HYLS1 hydrolethalus syndrome 1 -1.68607
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -1.68468
MTDH metadherin -1.68101
LMBRD1 LMBR1 domain containing 1 -1.68001
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -1.6787
KDM4C lysine (K)-specific demethylase 4C -1.67869
FAM160A2 family with sequence similarity 160, member A2 -1.67623
FOXC2 forkhead box C2 -1.67522
ARCN1 archain 1 -1.67459
OR5V1 olfactory receptor, family 5, subfamily V, member 1 -1.66968
ATG12 autophagy related 12 -1.66947
NDFIP1 Nedd4 family interacting protein 1 -1.66771
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -1.66705
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -1.66515
ZNF358 zinc finger protein 358 -1.66414
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -1.66178
UBE2W ubiquitin-conjugating enzyme E2W (putative) -1.66007
CORIN corin, serine peptidase -1.6526
SNX17 sorting nexin 17 -1.64873
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -1.64559
LRP11 low density lipoprotein receptor-related protein 11 -1.64263
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -1.64039
DCK deoxycytidine kinase -1.64007
GALK2 galactokinase 2 -1.63482
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 -1.63068
NSUN7 NOP2/Sun domain family, member 7 -1.63016
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -1.6298
MYZAP myocardial zonula adherens protein -1.62878
TRAPPC13 trafficking protein particle complex 13 -1.62439
FMR1 fragile X mental retardation 1 -1.62376
GABPB1 GA binding protein transcription factor, beta subunit 1 -1.62281
SLFN11 schlafen family member 11 -1.6196
QARS glutaminyl-tRNA synthetase -1.6192
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -1.61866
AKAP8 A kinase (PRKA) anchor protein 8 -1.61769
FGF8 fibroblast growth factor 8 (androgen-induced) -1.61393
AVEN apoptosis, caspase activation inhibitor -1.61284
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -1.61248
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase -1.61219
FBXO2 F-box protein 2 -1.61028
ERMP1 endoplasmic reticulum metallopeptidase 1 -1.60904
ZNF304 zinc finger protein 304 -1.60527
DYSF dysferlin -1.60281
SYNDIG1L synapse differentiation inducing 1-like -1.60063
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 -1.5967
SCAF8 SR-related CTD-associated factor 8 -1.59664
BPGM 2,3-bisphosphoglycerate mutase -1.59639
ANKRD54 ankyrin repeat domain 54 -1.59404
UROS uroporphyrinogen III synthase -1.59308
TSC1 tuberous sclerosis 1 -1.59269
DPY19L2P2 DPY19L2 pseudogene 2 -1.5913
DGCR14 DiGeorge syndrome critical region gene 14 -1.59092
PPA2 pyrophosphatase (inorganic) 2 -1.59072
LPCAT4 lysophosphatidylcholine acyltransferase 4 -1.58994
TERF2IP telomeric repeat binding factor 2, interacting protein -1.58963
UBFD1 ubiquitin family domain containing 1 -1.58453
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -1.58415
BBIP1 BBSome interacting protein 1 -1.58384
FAM217B family with sequence similarity 217, member B -1.58373
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -1.5817
TMEM2 transmembrane protein 2 -1.58155
ZNF12 zinc finger protein 12 -1.58142
OPA1 optic atrophy 1 (autosomal dominant) -1.58065
SPAG7 sperm associated antigen 7 -1.57934
BIN1 bridging integrator 1 -1.57675
ACSS1 acyl-CoA synthetase short-chain family member 1 -1.57581
FKBP4 FK506 binding protein 4, 59kDa -1.57423
CREG1 cellular repressor of E1A-stimulated genes 1 -1.57353
SCHIP1 schwannomin interacting protein 1 -1.57328
POLG polymerase (DNA directed), gamma -1.5702
ZBTB47 zinc finger and BTB domain containing 47 -1.5702
KRBOX4 KRAB box domain containing 4 -1.56869
PDCD6IP programmed cell death 6 interacting protein -1.56847
CBR4 carbonyl reductase 4 -1.56804
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -1.56648
CARKD carbohydrate kinase domain containing -1.56607
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -1.56292
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 -1.56246
C11ORF57 chromosome 11 open reading frame 57 -1.55889
ULK2 unc-51 like autophagy activating kinase 2 -1.55717
OTUD6B-AS1 OTUD6B antisense RNA 1 (head to head) -1.55698
TSGA13 testis specific, 13 -1.55605
CLCN1 chloride channel, voltage-sensitive 1 -1.55519
DENND4B DENN/MADD domain containing 4B -1.55341
MUC2 mucin 2, oligomeric mucus/gel-forming -1.55207
GATA3 GATA binding protein 3 -1.55083
CTBP1 C-terminal binding protein 1 -1.5437
TACR1 tachykinin receptor 1 -1.54366
PORCN porcupine homolog (Drosophila) -1.54278
TRIM13 tripartite motif containing 13 -1.54232
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -1.5417
KIAA1191 KIAA1191 -1.5384
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -1.53736
PROSER1 proline and serine rich 1 -1.53642
FIG4 FIG4 phosphoinositide 5-phosphatase -1.53486
GRAMD3 GRAM domain containing 3 -1.53471
PRDM5 PR domain containing 5 -1.53339