HIPK2_defectivemutant_17_GDS1793 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS1793
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Genes

600 genes differentially expressed following the HIPK2_defectivemutant_17_GDS1793 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
YIPF4 Yip1 domain family, member 4 3.6375
WSB2 WD repeat and SOCS box containing 2 3.32919
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 3.26195
SDK2 sidekick cell adhesion molecule 2 3.20308
CNOT6L CCR4-NOT transcription complex, subunit 6-like 3.19501
SMAD4 SMAD family member 4 3.1298
ACO1 aconitase 1, soluble 3.04565
USP24 ubiquitin specific peptidase 24 3.02754
LASP1 LIM and SH3 protein 1 2.82904
NKX2-6 NK2 homeobox 6 2.78842
PCOLCE2 procollagen C-endopeptidase enhancer 2 2.76206
ZNF384 zinc finger protein 384 2.76189
FAM101B family with sequence similarity 101, member B 2.75196
ETAA1 Ewing tumor-associated antigen 1 2.61822
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.5901
MYCBP MYC binding protein 2.5879
RAB14 RAB14, member RAS oncogene family 2.58146
STK10 serine/threonine kinase 10 2.57731
ACAT1 acetyl-CoA acetyltransferase 1 2.53439
PMVK phosphomevalonate kinase 2.52094
MKS1 Meckel syndrome, type 1 2.49339
DOCK11 dedicator of cytokinesis 11 2.47934
ZNF704 zinc finger protein 704 2.43092
GATAD2B GATA zinc finger domain containing 2B 2.4276
EPB41L3 erythrocyte membrane protein band 4.1-like 3 2.42752
H2AFY2 H2A histone family, member Y2 2.3948
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2.37198
ZFR zinc finger RNA binding protein 2.36147
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 2.36085
SYT11 synaptotagmin XI 2.34907
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.34583
F2R coagulation factor II (thrombin) receptor 2.33837
CLCN5 chloride channel, voltage-sensitive 5 2.3313
ZNF408 zinc finger protein 408 2.32725
HAUS4 HAUS augmin-like complex, subunit 4 2.32632
NDN necdin, melanoma antigen (MAGE) family member 2.32484
FAM13B family with sequence similarity 13, member B 2.3239
FGD5 FYVE, RhoGEF and PH domain containing 5 2.32081
AGFG2 ArfGAP with FG repeats 2 2.32047
ORC4 origin recognition complex, subunit 4 2.29469
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.28437
SLIT2 slit homolog 2 (Drosophila) 2.27461
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 2.27111
DUSP16 dual specificity phosphatase 16 2.26797
YBX1 Y box binding protein 1 2.25369
NANS N-acetylneuraminic acid synthase 2.24449
CD53 CD53 molecule 2.23553
STAG1 stromal antigen 1 2.23376
TARBP2 TAR (HIV-1) RNA binding protein 2 2.21819
GLG1 golgi glycoprotein 1 2.21198
METTL4 methyltransferase like 4 2.20827
RABEPK Rab9 effector protein with kelch motifs 2.20201
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.19091
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 2.18423
RNF121 ring finger protein 121 2.1763
SNX33 sorting nexin 33 2.17516
SCP2 sterol carrier protein 2 2.17203
EFHC1 EF-hand domain (C-terminal) containing 1 2.1719
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.17143
FICD FIC domain containing 2.16935
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 2.16572
TMOD3 tropomodulin 3 (ubiquitous) 2.16406
HOOK3 hook microtubule-tethering protein 3 2.15257
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.14973
SENP6 SUMO1/sentrin specific peptidase 6 2.14443
RPN1 ribophorin I 2.13158
LPPR1 lipid phosphate phosphatase-related protein type 1 2.12819
C8ORF58 chromosome 8 open reading frame 58 2.12417
TMEM50A transmembrane protein 50A 2.11726
SPINT2 serine peptidase inhibitor, Kunitz type, 2 2.11087
ENDOD1 endonuclease domain containing 1 2.1047
LRRC47 leucine rich repeat containing 47 2.10108
RTN1 reticulon 1 2.09946
C18ORF32 chromosome 18 open reading frame 32 2.09827
BTNL9 butyrophilin-like 9 2.09518
ZBTB10 zinc finger and BTB domain containing 10 2.08834
C10ORF88 chromosome 10 open reading frame 88 2.07667
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 2.07373
PCNP PEST proteolytic signal containing nuclear protein 2.07341
HSPA9 heat shock 70kDa protein 9 (mortalin) 2.07105
FAM136A family with sequence similarity 136, member A 2.06617
GPC6 glypican 6 2.06477
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 2.05172
MIER2 mesoderm induction early response 1, family member 2 2.04099
RNF170 ring finger protein 170 2.03788
FNDC3B fibronectin type III domain containing 3B 2.02796
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 2.00722
REEP3 receptor accessory protein 3 2.00484
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.00295
MAP4 microtubule-associated protein 4 1.99064
PHKA1 phosphorylase kinase, alpha 1 (muscle) 1.98986
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 1.97589
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 1.96365
GTPBP2 GTP binding protein 2 1.95811
TSNAX translin-associated factor X 1.95625
C6ORF62 chromosome 6 open reading frame 62 1.95161
RUNX2 runt-related transcription factor 2 1.93842
NKX2-4 NK2 homeobox 4 1.93596
KRBA1 KRAB-A domain containing 1 1.93526
TMTC3 transmembrane and tetratricopeptide repeat containing 3 1.93371
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.92349
PTPDC1 protein tyrosine phosphatase domain containing 1 1.9231
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 1.92206
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.9186
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.91837
RAB1A RAB1A, member RAS oncogene family 1.91205
PLXNA2 plexin A2 1.91092
GSAP gamma-secretase activating protein 1.90831
RAD18 RAD18 E3 ubiquitin protein ligase 1.90807
CLGN calmegin 1.90806
MTMR3 myotubularin related protein 3 1.90563
BOD1L1 biorientation of chromosomes in cell division 1-like 1 1.90348
RMI1 RecQ mediated genome instability 1 1.90225
NLK nemo-like kinase 1.89135
SYS1 Sys1 golgi trafficking protein 1.88948
CCDC47 coiled-coil domain containing 47 1.88501
SPTBN1 spectrin, beta, non-erythrocytic 1 1.881
GOLGA3 golgin A3 1.87746
SATB1 SATB homeobox 1 1.8683
STOX2 storkhead box 2 1.86749
AMER1 APC membrane recruitment protein 1 1.86727
STRADB STE20-related kinase adaptor beta 1.86685
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 1.8664
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 1.86132
WDR89 WD repeat domain 89 1.85266
NUP54 nucleoporin 54kDa 1.85264
ACTN4 actinin, alpha 4 1.83581
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.8344
TRRAP transformation/transcription domain-associated protein 1.83024
TFB2M transcription factor B2, mitochondrial 1.8293
TMEM127 transmembrane protein 127 1.82629
STAU1 staufen double-stranded RNA binding protein 1 1.82529
HNRNPR heterogeneous nuclear ribonucleoprotein R 1.82455
PHF8 PHD finger protein 8 1.81812
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1.81677
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 1.80802
SCARB2 scavenger receptor class B, member 2 1.80565
PRDM15 PR domain containing 15 1.80425
EXOC6 exocyst complex component 6 1.79885
OLA1 Obg-like ATPase 1 1.79862
ZNF24 zinc finger protein 24 1.79719
SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.79676
TPRG1L tumor protein p63 regulated 1-like 1.79638
ZBTB7A zinc finger and BTB domain containing 7A 1.79257
COPA coatomer protein complex, subunit alpha 1.78902
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.7815
FLCN folliculin 1.78049
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.77835
PBRM1 polybromo 1 1.77682
ARHGAP24 Rho GTPase activating protein 24 1.7713
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 1.76939
SPRED3 sprouty-related, EVH1 domain containing 3 1.76815
C6ORF89 chromosome 6 open reading frame 89 1.76039
RHOBTB3 Rho-related BTB domain containing 3 1.76019
TMEM60 transmembrane protein 60 1.75358
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 1.74888
ADCY1 adenylate cyclase 1 (brain) 1.74363
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 1.7433
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.74327
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 1.74179
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 1.73733
WBP1 WW domain binding protein 1 1.73461
SLC35A5 solute carrier family 35, member A5 1.73039
LGALSL lectin, galactoside-binding-like 1.72829
MAP7D2 MAP7 domain containing 2 1.72771
RESP18 regulated endocrine-specific protein 18 1.72715
C16ORF52 chromosome 16 open reading frame 52 1.7201
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.71879
MPV17 MpV17 mitochondrial inner membrane protein 1.71165
TGFBR1 transforming growth factor, beta receptor 1 1.71034
SH3GLB1 SH3-domain GRB2-like endophilin B1 1.70792
OLFM1 olfactomedin 1 1.70493
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.70453
RHEB Ras homolog enriched in brain 1.70114
ZNF407 zinc finger protein 407 1.70048
RAB5A RAB5A, member RAS oncogene family 1.69886
THRB thyroid hormone receptor, beta 1.69862
UBE2I ubiquitin-conjugating enzyme E2I 1.69453
SRSF7 serine/arginine-rich splicing factor 7 1.69373
ACTG1 actin gamma 1 1.69313
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.69203
PTDSS2 phosphatidylserine synthase 2 1.69187
FASTKD2 FAST kinase domains 2 1.68939
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 1.68753
TRIP4 thyroid hormone receptor interactor 4 1.68746
KANSL2 KAT8 regulatory NSL complex subunit 2 1.68423
SNX18 sorting nexin 18 1.68173
CDKL3 cyclin-dependent kinase-like 3 1.68135
NCALD neurocalcin delta 1.67866
AKAP8 A kinase (PRKA) anchor protein 8 1.67748
ZNF827 zinc finger protein 827 1.67522
MYO5B myosin VB 1.67089
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 1.66557
PBX2 pre-B-cell leukemia homeobox 2 1.66547
ACBD5 acyl-CoA binding domain containing 5 1.66498
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.66479
ERRFI1 ERBB receptor feedback inhibitor 1 1.65636
NUPL2 nucleoporin like 2 1.65402
KLF7 Kruppel-like factor 7 (ubiquitous) 1.65366
CLN5 ceroid-lipofuscinosis, neuronal 5 1.65181
TCP1 t-complex 1 1.64801
UBE4A ubiquitination factor E4A 1.64501
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 1.64014
SPATA9 spermatogenesis associated 9 1.63793
MUTYH mutY homolog 1.63678
AMIGO1 adhesion molecule with Ig-like domain 1 1.63633
EDNRB endothelin receptor type B 1.63316
FGF7 fibroblast growth factor 7 1.62573
LGALS9B lectin, galactoside-binding, soluble, 9B 1.62356
HIP1 huntingtin interacting protein 1 1.62159
FAM63A family with sequence similarity 63, member A 1.62157
UXS1 UDP-glucuronate decarboxylase 1 1.62128
SLC25A44 solute carrier family 25, member 44 1.62098
NHLRC3 NHL repeat containing 3 1.61955
MED11 mediator complex subunit 11 1.6187
GDE1 glycerophosphodiester phosphodiesterase 1 1.61179
AQP8 aquaporin 8 1.60468
DAPK2 death-associated protein kinase 2 1.60428
HIBADH 3-hydroxyisobutyrate dehydrogenase 1.60336
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 1.60112
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 1.59789
UBXN4 UBX domain protein 4 1.59674
ZNF729 zinc finger protein 729 1.5947
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 1.59406
LAMP1 lysosomal-associated membrane protein 1 1.59361
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.59347
ZNF207 zinc finger protein 207 1.59335
C9ORF114 chromosome 9 open reading frame 114 1.5932
PCNXL3 pecanex-like 3 (Drosophila) 1.59247
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.58975
ZSCAN12 zinc finger and SCAN domain containing 12 1.58621
COQ3 coenzyme Q3 methyltransferase 1.58549
GAN gigaxonin 1.58455
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 1.58262
CNTN1 contactin 1 1.58235
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 1.58115
SEPT7 septin 7 1.57942
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B 1.57939
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 1.57355
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 1.56559
CCDC39 coiled-coil domain containing 39 1.56179
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 1.5612
ELAVL2 ELAV like neuron-specific RNA binding protein 2 1.55955
DCAF15 DDB1 and CUL4 associated factor 15 1.55888
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 1.55856
GSS glutathione synthetase 1.55459
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1.55459
TACC1 transforming, acidic coiled-coil containing protein 1 1.55297
CRAMP1L Crm, cramped-like (Drosophila) 1.55248
MATR3 matrin 3 1.54922
KBTBD3 kelch repeat and BTB (POZ) domain containing 3 1.54882
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.54829
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.5459
EIF3E eukaryotic translation initiation factor 3, subunit E 1.54521
GMFG glia maturation factor, gamma 1.5448
LCOR ligand dependent nuclear receptor corepressor 1.54423
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.541
TRPM4 transient receptor potential cation channel, subfamily M, member 4 1.5392
CD300LF CD300 molecule-like family member f 1.53565
ADGRF4 adhesion G protein-coupled receptor F4 1.53324
IQCA1 IQ motif containing with AAA domain 1 1.53123
NAT14 N-acetyltransferase 14 (GCN5-related, putative) 1.53071
WBSCR16 Williams-Beuren syndrome chromosome region 16 1.53015
WHSC1 Wolf-Hirschhorn syndrome candidate 1 1.52989
S100A5 S100 calcium binding protein A5 1.52974
TOX4 TOX high mobility group box family member 4 1.52963
PALLD palladin, cytoskeletal associated protein 1.52894
CHD9 chromodomain helicase DNA binding protein 9 1.52843
MRPL24 mitochondrial ribosomal protein L24 1.52431
JMJD1C jumonji domain containing 1C 1.524
CCDC61 coiled-coil domain containing 61 1.52231
PPAP2C phosphatidic acid phosphatase type 2C 1.52173
UGP2 UDP-glucose pyrophosphorylase 2 1.5212
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.52026
RAB39B RAB39B, member RAS oncogene family 1.5189
MDC1 mediator of DNA-damage checkpoint 1 1.51758
FANCB Fanconi anemia, complementation group B 1.51659
ATXN2L ataxin 2-like 1.51598
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.51426
RFX7 regulatory factor X, 7 1.51158
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 1.51019
PCSK7 proprotein convertase subtilisin/kexin type 7 1.50557
TMCC1 transmembrane and coiled-coil domain family 1 1.50534
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 1.50446
ROR2 receptor tyrosine kinase-like orphan receptor 2 1.50421
PLEC plectin 1.50175
RGL2 ral guanine nucleotide dissociation stimulator-like 2 1.50042
TCAF1 TRPM8 channel-associated factor 1 1.49861
MTMR9 myotubularin related protein 9 1.4979
ACTB actin, beta 1.49765
CCAR2 cell cycle and apoptosis regulator 2 1.49519
SDAD1 SDA1 domain containing 1 1.49464
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.49238
MTA3 metastasis associated 1 family, member 3 1.4897
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.48888
CDV3 CDV3 homolog (mouse) 1.48875
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 1.48775
CYFIP1 cytoplasmic FMR1 interacting protein 1 1.48747
WDR33 WD repeat domain 33 1.48746
U2AF2 U2 small nuclear RNA auxiliary factor 2 1.48723

decreased expression

Symbol Name Standardized Value
PLP1 proteolipid protein 1 -3.88875
ETFB electron-transfer-flavoprotein, beta polypeptide -3.82762
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.49773
TMX4 thioredoxin-related transmembrane protein 4 -3.3594
B3GNT1 -3.33564
TMBIM6 transmembrane BAX inhibitor motif containing 6 -3.32213
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) -3.27318
WDR53 WD repeat domain 53 -3.2573
PPP4R2 protein phosphatase 4, regulatory subunit 2 -3.24989
RPP14 ribonuclease P/MRP 14kDa subunit -3.24832
LIMD1 LIM domains containing 1 -3.19119
CACNB3 calcium channel, voltage-dependent, beta 3 subunit -3.07526
EXOSC7 exosome component 7 -3.01906
RASA3 RAS p21 protein activator 3 -2.94245
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -2.87955
RANBP17 RAN binding protein 17 -2.84331
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.76048
GPHN gephyrin -2.72553
NDRG2 NDRG family member 2 -2.70738
MAOB monoamine oxidase B -2.70128
CDK19 cyclin-dependent kinase 19 -2.69446
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.67369
CHGB chromogranin B -2.66787
RPUSD4 RNA pseudouridylate synthase domain containing 4 -2.66666
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) -2.6551
MMD2 monocyte to macrophage differentiation-associated 2 -2.65182
HRAS Harvey rat sarcoma viral oncogene homolog -2.62118
LRRC2 leucine rich repeat containing 2 -2.5833
ZNF496 zinc finger protein 496 -2.57253
MTERF2 mitochondrial transcription termination factor 2 -2.56906
SAE1 SUMO1 activating enzyme subunit 1 -2.55486
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -2.55422
NMT2 N-myristoyltransferase 2 -2.54929
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -2.5092
GID4 GID complex subunit 4 -2.50418
NR2F1 nuclear receptor subfamily 2, group F, member 1 -2.50015
RPP40 ribonuclease P/MRP 40kDa subunit -2.48941
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.47845
ABT1 activator of basal transcription 1 -2.47411
EGLN2 egl-9 family hypoxia-inducible factor 2 -2.47305
FBXO10 F-box protein 10 -2.46312
MRPS6 mitochondrial ribosomal protein S6 -2.45972
ZMYND19 zinc finger, MYND-type containing 19 -2.45853
MICU2 mitochondrial calcium uptake 2 -2.45521
SHISA4 shisa family member 4 -2.41206
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.40687
MAPK4 mitogen-activated protein kinase 4 -2.40581
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa -2.40227
TMEM126A transmembrane protein 126A -2.39128
GCLC glutamate-cysteine ligase, catalytic subunit -2.38904
LZIC leucine zipper and CTNNBIP1 domain containing -2.37262
TMED1 transmembrane emp24 protein transport domain containing 1 -2.35036
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -2.32688
DLK2 delta-like 2 homolog (Drosophila) -2.32008
MAGOHB mago-nashi homolog B (Drosophila) -2.3193
DNAAF2 dynein, axonemal, assembly factor 2 -2.28204
RPS3 ribosomal protein S3 -2.28041
UBXN7 UBX domain protein 7 -2.27748
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -2.25606
PHOSPHO2 phosphatase, orphan 2 -2.25444
UBE3C ubiquitin protein ligase E3C -2.25321
CGGBP1 CGG triplet repeat binding protein 1 -2.25138
RANBP10 RAN binding protein 10 -2.24745
PDF peptide deformylase (mitochondrial) -2.23494
QDPR quinoid dihydropteridine reductase -2.2031
AK2 adenylate kinase 2 -2.19594
CTSD cathepsin D -2.19498
PAK1IP1 PAK1 interacting protein 1 -2.19287
MOB4 MOB family member 4, phocein -2.1806
WDR43 WD repeat domain 43 -2.17893
TXNL4B thioredoxin-like 4B -2.17005
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.16308
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -2.15156
RSBN1 round spermatid basic protein 1 -2.1473
LY86 lymphocyte antigen 86 -2.14434
UXT ubiquitously-expressed, prefoldin-like chaperone -2.14395
MBTPS1 membrane-bound transcription factor peptidase, site 1 -2.13064
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B -2.12846
PCDH7 protocadherin 7 -2.12781
LRRC42 leucine rich repeat containing 42 -2.11047
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.10426
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.10422
MCL1 myeloid cell leukemia 1 -2.10204
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.10132
SEC63 SEC63 homolog (S. cerevisiae) -2.09622
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 -2.09338
CHP1 calcineurin-like EF-hand protein 1 -2.0906
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) -2.08597
CCDC167 coiled-coil domain containing 167 -2.08415
SGPP1 sphingosine-1-phosphate phosphatase 1 -2.08397
CHGA chromogranin A -2.0807
UBA5 ubiquitin-like modifier activating enzyme 5 -2.07802
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) -2.07671
SFR1 SWI5-dependent recombination repair 1 -2.07368
PREPL prolyl endopeptidase-like -2.06547
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -2.0595
XAB2 XPA binding protein 2 -2.04794
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 -2.04613
CKS1B CDC28 protein kinase regulatory subunit 1B -2.02651
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted -2.01863
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -2.01025
KPNB1 karyopherin (importin) beta 1 -2.00787
RFC2 replication factor C (activator 1) 2, 40kDa -1.99851
MINOS1 mitochondrial inner membrane organizing system 1 -1.98725
NKD2 naked cuticle homolog 2 (Drosophila) -1.98372
FPGT fucose-1-phosphate guanylyltransferase -1.98246
VTI1B vesicle transport through interaction with t-SNAREs 1B -1.97828
SARS seryl-tRNA synthetase -1.97769
GSKIP GSK3B interacting protein -1.97686
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -1.97383
KIAA1143 KIAA1143 -1.97118
IFT22 intraflagellar transport 22 -1.97034
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -1.96586
ATP9B ATPase, class II, type 9B -1.96378
CCNDBP1 cyclin D-type binding-protein 1 -1.96254
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -1.96046
PPIH peptidylprolyl isomerase H (cyclophilin H) -1.95722
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -1.95421
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -1.94755
DAP death-associated protein -1.94722
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.94384
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -1.94155
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -1.94081
PSAT1 phosphoserine aminotransferase 1 -1.93661
ABHD17C abhydrolase domain containing 17C -1.93546
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -1.92792
UBXN6 UBX domain protein 6 -1.92605
TMCO1 transmembrane and coiled-coil domains 1 -1.91324
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -1.912
LRRC40 leucine rich repeat containing 40 -1.91064
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit -1.90497
BBS10 Bardet-Biedl syndrome 10 -1.90151
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -1.89942
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) -1.88954
COL4A5 collagen, type IV, alpha 5 -1.88238
CBX1 chromobox homolog 1 -1.87315
SEC61G Sec61 gamma subunit -1.87314
KCTD6 potassium channel tetramerization domain containing 6 -1.87312
IFT80 intraflagellar transport 80 -1.86603
TMEM160 transmembrane protein 160 -1.86544
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -1.86101
MVB12B multivesicular body subunit 12B -1.85907
CPSF3L cleavage and polyadenylation specific factor 3-like -1.8485
RNF115 ring finger protein 115 -1.8411
SPRED1 sprouty-related, EVH1 domain containing 1 -1.83449
CEPT1 choline/ethanolamine phosphotransferase 1 -1.82561
TCP11L2 t-complex 11, testis-specific-like 2 -1.82218
KRTDAP keratinocyte differentiation-associated protein -1.82173
ADSSL1 adenylosuccinate synthase like 1 -1.82032
MEGF10 multiple EGF-like-domains 10 -1.8188
MRPL28 mitochondrial ribosomal protein L28 -1.81654
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 -1.81549
MTUS1 microtubule associated tumor suppressor 1 -1.81536
EID1 EP300 interacting inhibitor of differentiation 1 -1.81379
SART1 squamous cell carcinoma antigen recognized by T cells -1.80974
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -1.80459
EMC3 ER membrane protein complex subunit 3 -1.80443
SOX2 SRY (sex determining region Y)-box 2 -1.80419
TTC28 tetratricopeptide repeat domain 28 -1.80353
EMC4 ER membrane protein complex subunit 4 -1.80335
PEX11B peroxisomal biogenesis factor 11 beta -1.8026
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -1.8021
TBC1D4 TBC1 domain family, member 4 -1.80162
WDR45 WD repeat domain 45 -1.79961
LRWD1 leucine-rich repeats and WD repeat domain containing 1 -1.79395
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -1.79389
SMYD2 SET and MYND domain containing 2 -1.79133
PNCK pregnancy up-regulated nonubiquitous CaM kinase -1.78769
LRRN1 leucine rich repeat neuronal 1 -1.78643
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -1.78614
NARF nuclear prelamin A recognition factor -1.7828
SERGEF secretion regulating guanine nucleotide exchange factor -1.77895
PAPOLG poly(A) polymerase gamma -1.77641
HINT1 histidine triad nucleotide binding protein 1 -1.77623
FASTKD5 FAST kinase domains 5 -1.77469
NANP N-acetylneuraminic acid phosphatase -1.76926
KANK4 KN motif and ankyrin repeat domains 4 -1.75512
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -1.75469
BAG1 BCL2-associated athanogene -1.75254
ADPRHL2 ADP-ribosylhydrolase like 2 -1.74742
RBM26 RNA binding motif protein 26 -1.74613
PLEKHO1 pleckstrin homology domain containing, family O member 1 -1.74497
STK16 serine/threonine kinase 16 -1.74357
C4ORF19 chromosome 4 open reading frame 19 -1.74212
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -1.73812
OFD1 oral-facial-digital syndrome 1 -1.73457
SF3B2 splicing factor 3b, subunit 2, 145kDa -1.73044
ELP3 elongator acetyltransferase complex subunit 3 -1.72843
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -1.72771
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -1.72604
ADCK1 aarF domain containing kinase 1 -1.72022
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.71664
TSPAN5 tetraspanin 5 -1.71573
M6PR mannose-6-phosphate receptor (cation dependent) -1.71426
USP39 ubiquitin specific peptidase 39 -1.71163
MRPS34 mitochondrial ribosomal protein S34 -1.71045
EIF3K eukaryotic translation initiation factor 3, subunit K -1.70927
CEP19 centrosomal protein 19kDa -1.70663
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -1.70425
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -1.7031
MSL3 male-specific lethal 3 homolog (Drosophila) -1.70251
ZRANB1 zinc finger, RAN-binding domain containing 1 -1.6936
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 -1.69297
TMEM178A transmembrane protein 178A -1.69167
COMMD3 COMM domain containing 3 -1.69008
ZNF398 zinc finger protein 398 -1.68753
OSER1 oxidative stress responsive serine-rich 1 -1.68668
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -1.685
AZI2 5-azacytidine induced 2 -1.6825
SNX16 sorting nexin 16 -1.67626
ERGIC3 ERGIC and golgi 3 -1.6755
TPI1 triosephosphate isomerase 1 -1.67536
DSEL dermatan sulfate epimerase-like -1.67367
SSRP1 structure specific recognition protein 1 -1.66903
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.66885
KIAA0355 KIAA0355 -1.66881
PANX1 pannexin 1 -1.6673
ERO1L ERO1-like (S. cerevisiae) -1.66397
SAMD1 sterile alpha motif domain containing 1 -1.65887
KIAA0319L KIAA0319-like -1.65546
MYO18A myosin XVIIIA -1.65449
LZTS2 leucine zipper, putative tumor suppressor 2 -1.6537
CLDN22 claudin 22 -1.65342
PSMC3IP PSMC3 interacting protein -1.65231
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -1.65202
C12ORF4 chromosome 12 open reading frame 4 -1.651
MTAP methylthioadenosine phosphorylase -1.64958
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase -1.64909
MED23 mediator complex subunit 23 -1.64901
MPZ myelin protein zero -1.64551
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 -1.64314
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 -1.64269
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) -1.63992
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -1.63986
TSC22D3 TSC22 domain family, member 3 -1.63836
DCTN2 dynactin 2 (p50) -1.63778
CBX5 chromobox homolog 5 -1.63721
ZMYM1 zinc finger, MYM-type 1 -1.635
RHOC ras homolog family member C -1.63212
TMEM185B transmembrane protein 185B -1.631
CTTNBP2NL CTTNBP2 N-terminal like -1.63029
PUS3 pseudouridylate synthase 3 -1.62616
SNAP91 synaptosomal-associated protein, 91kDa -1.62339
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) -1.62308
GSTM3 glutathione S-transferase mu 3 (brain) -1.62303
BCL7C B-cell CLL/lymphoma 7C -1.62213
PPP1R21 protein phosphatase 1, regulatory subunit 21 -1.61679
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 -1.61565
ZHX2 zinc fingers and homeoboxes 2 -1.61447
NAT8L N-acetyltransferase 8-like (GCN5-related, putative) -1.61391
ZNF131 zinc finger protein 131 -1.61354
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -1.61197
CDC37L1 cell division cycle 37-like 1 -1.61121
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.60922
DLAT dihydrolipoamide S-acetyltransferase -1.60682
MID1IP1 MID1 interacting protein 1 -1.60578
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -1.60169
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -1.60053
ZUFSP zinc finger with UFM1-specific peptidase domain -1.59926
DTYMK deoxythymidylate kinase (thymidylate kinase) -1.59555
ARFIP1 ADP-ribosylation factor interacting protein 1 -1.59097
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.58737
TMEM135 transmembrane protein 135 -1.58669
CXORF56 chromosome X open reading frame 56 -1.5828
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.58124
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -1.58024
RPL12 ribosomal protein L12 -1.58017
PEX26 peroxisomal biogenesis factor 26 -1.5801
IFT81 intraflagellar transport 81 -1.5793
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -1.57498
SLITRK1 SLIT and NTRK-like family, member 1 -1.57111
TMUB2 transmembrane and ubiquitin-like domain containing 2 -1.57059
FAM50A family with sequence similarity 50, member A -1.56849
BET1L Bet1 golgi vesicular membrane trafficking protein-like -1.56848
ZMYM2 zinc finger, MYM-type 2 -1.56636
GRWD1 glutamate-rich WD repeat containing 1 -1.56602
CYB5A cytochrome b5 type A (microsomal) -1.56382
CDADC1 cytidine and dCMP deaminase domain containing 1 -1.56354
DLC1 DLC1 Rho GTPase activating protein -1.5628
RPA3 replication protein A3, 14kDa -1.56248
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -1.56247
TMEM163 transmembrane protein 163 -1.56221
GYG1 glycogenin 1 -1.55798
CCDC51 coiled-coil domain containing 51 -1.5576
TCAP titin-cap -1.55625
HAUS6 HAUS augmin-like complex, subunit 6 -1.55601
PRMT8 protein arginine methyltransferase 8 -1.55315
LIG1 ligase I, DNA, ATP-dependent -1.55167
FIGN fidgetin -1.55129
TBC1D19 TBC1 domain family, member 19 -1.5506
CFDP1 craniofacial development protein 1 -1.55028
SKAP2 src kinase associated phosphoprotein 2 -1.54793
MRPS18C mitochondrial ribosomal protein S18C -1.54539
NXPE4 neurexophilin and PC-esterase domain family, member 4 -1.54361
ITM2A integral membrane protein 2A -1.53932
RELL1 RELT-like 1 -1.53913
UFD1L ubiquitin fusion degradation 1 like (yeast) -1.53435
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -1.53339
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.53069
CAND2 cullin-associated and neddylation-dissociated 2 (putative) -1.52937