HIPK2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description homeodomain interacting protein kinase 2|This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 28996)
External Link http://www.ncbi.nlm.nih.gov/gene/28996
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Genes

66 interacting proteins for HIPK2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AXIN1 axin 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHMP4B charged multivesicular body protein 4B
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CTBP1 C-terminal binding protein 1
CUL1 cullin 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DAXX death-domain associated protein
DCAF7 DDB1 and CUL4 associated factor 7
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EP300 E1A binding protein p300
FBXO3 F-box protein 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHL2 four and a half LIM domains 2
HIST2H2BE histone cluster 2, H2be
HMGA1 high mobility group AT-hook 1
KAT2B K(lysine) acetyltransferase 2B
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MBP myelin basic protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEF2C myocyte enhancer factor 2C
MKNK1 MAP kinase interacting serine/threonine kinase 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NKX2-1 NK2 homeobox 1
NKX2-5 NK2 homeobox 5
NKX3-1 NK3 homeobox 1
NLK nemo-like kinase
PAX6 paired box 6
PML promyelocytic leukemia
PTCH1 patched 1
RANBP9 RAN binding protein 9
RUNX1 runt-related transcription factor 1
SENP1 SUMO1/sentrin specific peptidase 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SKI SKI proto-oncogene
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SP100 SP100 nuclear antigen
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRADD TNFRSF1A-associated via death domain
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
WSB1 WD repeat and SOCS box containing 1
ZBTB4 zinc finger and BTB domain containing 4