HIPK2 Gene Set

Dataset KEA Substrates of Kinases
Category physical interactions
Type kinase
Description homeodomain interacting protein kinase 2|This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 28996)
External Link http://www.ncbi.nlm.nih.gov/gene/28996
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Genes

20 substrates of the kinase HIPK2 from the curated KEA Substrates of Kinases dataset.

Symbol Name
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CREB1 cAMP responsive element binding protein 1
CTBP1 C-terminal binding protein 1
CTBP2 C-terminal binding protein 2
CUL1 cullin 1
EP300 E1A binding protein p300
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
HMGA1 high mobility group AT-hook 1
KAT2B K(lysine) acetyltransferase 2B
MECP2 methyl CpG binding protein 2
PAX6 paired box 6
PDX1 pancreatic and duodenal homeobox 1
PML promyelocytic leukemia
RUNX1 runt-related transcription factor 1
SIAH2 siah E3 ubiquitin protein ligase 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TP53 tumor protein p53
ZBTB4 zinc finger and BTB domain containing 4