HIPK1_knockout_170_GSE39253 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE39253
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Genes

600 genes differentially expressed following the HIPK1_knockout_170_GSE39253 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
TCF21 transcription factor 21 5.04397
SNX12 sorting nexin 12 3.79856
PI16 peptidase inhibitor 16 3.72386
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 3.71566
RNGTT RNA guanylyltransferase and 5'-phosphatase 3.63797
MBIP MAP3K12 binding inhibitory protein 1 3.56015
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 3.53444
KLF13 Kruppel-like factor 13 3.20166
IQCB1 IQ motif containing B1 3.19028
LUC7L LUC7-like (S. cerevisiae) 3.18309
GRPR gastrin-releasing peptide receptor 3.17902
SCN4A sodium channel, voltage gated, type IV alpha subunit 3.16655
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 3.12664
TOP3A topoisomerase (DNA) III alpha 3.06926
C7ORF55 chromosome 7 open reading frame 55 3.03746
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 2.95608
CD19 CD19 molecule 2.95605
OR5V1 olfactory receptor, family 5, subfamily V, member 1 2.93528
RNF38 ring finger protein 38 2.87587
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.87551
ZNF184 zinc finger protein 184 2.87254
TRIM27 tripartite motif containing 27 2.83281
SEC23B Sec23 homolog B (S. cerevisiae) 2.82624
IPO11 importin 11 2.81175
SFTPB surfactant protein B 2.80569
TACR2 tachykinin receptor 2 2.78778
CHRM4 cholinergic receptor, muscarinic 4 2.77693
SRPK1 SRSF protein kinase 1 2.75577
PRIM2 primase, DNA, polypeptide 2 (58kDa) 2.7551
ZBTB24 zinc finger and BTB domain containing 24 2.71563
TWSG1 twisted gastrulation BMP signaling modulator 1 2.70344
UMPS uridine monophosphate synthetase 2.69605
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2.6567
DMTF1 cyclin D binding myb-like transcription factor 1 2.64628
BBS2 Bardet-Biedl syndrome 2 2.63318
PCP2 Purkinje cell protein 2 2.63037
C11ORF74 chromosome 11 open reading frame 74 2.61048
PIGS phosphatidylinositol glycan anchor biosynthesis, class S 2.6078
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.60758
CDC5L cell division cycle 5-like 2.57413
ANAPC13 anaphase promoting complex subunit 13 2.57021
CORO2B coronin, actin binding protein, 2B 2.56884
SGOL1 shugoshin-like 1 (S. pombe) 2.49403
SIGLEC8 sialic acid binding Ig-like lectin 8 2.4635
CHAF1A chromatin assembly factor 1, subunit A (p150) 2.45801
FXYD5 FXYD domain containing ion transport regulator 5 2.44852
EPHA5 EPH receptor A5 2.43297
BRCA1 breast cancer 1, early onset 2.42007
BCL3 B-cell CLL/lymphoma 3 2.4091
BRD8 bromodomain containing 8 2.40379
PBX3 pre-B-cell leukemia homeobox 3 2.39382
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.36409
ANPEP alanyl (membrane) aminopeptidase 2.35901
PON2 paraoxonase 2 2.35109
MEA1 male-enhanced antigen 1 2.34343
FIZ1 FLT3-interacting zinc finger 1 2.336
TRAF3 TNF receptor-associated factor 3 2.33365
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.33234
PANX1 pannexin 1 2.31262
POLH polymerase (DNA directed), eta 2.305
RAB24 RAB24, member RAS oncogene family 2.30307
NDE1 nudE neurodevelopment protein 1 2.29746
COPG2 coatomer protein complex, subunit gamma 2 2.28226
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 2.26383
DAZAP2 DAZ associated protein 2 2.25936
CA2 carbonic anhydrase II 2.25547
DGCR8 DGCR8 microprocessor complex subunit 2.25431
PDCD7 programmed cell death 7 2.25358
REG1B regenerating islet-derived 1 beta 2.25181
PCCA propionyl CoA carboxylase, alpha polypeptide 2.22518
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.20778
PROK2 prokineticin 2 2.20614
CDCA5 cell division cycle associated 5 2.19991
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 2.19425
TRIM10 tripartite motif containing 10 2.19414
TLK2 tousled-like kinase 2 2.16927
BRD7 bromodomain containing 7 2.14441
PRODH2 proline dehydrogenase (oxidase) 2 2.13444
C21ORF62 chromosome 21 open reading frame 62 2.12929
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.1273
ARRB2 arrestin, beta 2 2.1259
PCNX pecanex homolog (Drosophila) 2.12256
DMD dystrophin 2.11082
RARA retinoic acid receptor, alpha 2.08952
CRYGD crystallin, gamma D 2.08856
ANKRD32 ankyrin repeat domain 32 2.07335
KCTD6 potassium channel tetramerization domain containing 6 2.06351
TCEAL1 transcription elongation factor A (SII)-like 1 2.05341
ZNF878 zinc finger protein 878 2.04858
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.03934
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 2.02972
LRRC3 leucine rich repeat containing 3 2.01943
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 2.01203
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 2.01007
ZDHHC6 zinc finger, DHHC-type containing 6 2.00964
VAMP4 vesicle-associated membrane protein 4 2.00407
MTX1 metaxin 1 1.98958
ZFP62 ZFP62 zinc finger protein 1.98838
CCNT1 cyclin T1 1.98601
RABGAP1 RAB GTPase activating protein 1 1.98006
OR10H3 olfactory receptor, family 10, subfamily H, member 3 1.97398
LAG3 lymphocyte-activation gene 3 1.96726
VRK1 vaccinia related kinase 1 1.96152
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.95916
TLL1 tolloid-like 1 1.9578
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.9529
RACGAP1 Rac GTPase activating protein 1 1.95175
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.94635
SSH3 slingshot protein phosphatase 3 1.94573
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.93679
ZNF622 zinc finger protein 622 1.93042
FCHSD2 FCH and double SH3 domains 2 1.92881
CLSTN2 calsyntenin 2 1.91303
ARCN1 archain 1 1.91268
CENPA centromere protein A 1.91112
ZNF346 zinc finger protein 346 1.9099
MTF2 metal response element binding transcription factor 2 1.90941
LIN7B lin-7 homolog B (C. elegans) 1.89012
OPHN1 oligophrenin 1 1.88981
ADAR adenosine deaminase, RNA-specific 1.88898
TRIT1 tRNA isopentenyltransferase 1 1.88658
SCARB2 scavenger receptor class B, member 2 1.88541
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 1.88131
EPHA6 EPH receptor A6 1.87692
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.87331
SUFU suppressor of fused homolog (Drosophila) 1.86663
ACTL7A actin-like 7A 1.86038
CRY1 cryptochrome circadian clock 1 1.85524
CHN1 chimerin 1 1.84507
GPX7 glutathione peroxidase 7 1.84018
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1.83452
PLCL2 phospholipase C-like 2 1.83071
IL12A interleukin 12A 1.81107
ADRA2B adrenoceptor alpha 2B 1.80733
HLA-G major histocompatibility complex, class I, G 1.80026
HM13 histocompatibility (minor) 13 1.79961
GTF3A general transcription factor IIIA 1.79955
RAB18 RAB18, member RAS oncogene family 1.79437
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.78633
SLC26A11 solute carrier family 26 (anion exchanger), member 11 1.78524
RSBN1 round spermatid basic protein 1 1.77997
RUFY2 RUN and FYVE domain containing 2 1.77742
GJA8 gap junction protein, alpha 8, 50kDa 1.75857
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.75782
KCTD5 potassium channel tetramerization domain containing 5 1.75718
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 1.75211
PPP1R8 protein phosphatase 1, regulatory subunit 8 1.7468
PANK2 pantothenate kinase 2 1.7435
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.73453
PPHLN1 periphilin 1 1.72908
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 1.72754
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.72327
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 1.71837
ARMCX3 armadillo repeat containing, X-linked 3 1.71788
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1.71504
ACO2 aconitase 2, mitochondrial 1.7059
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.70575
TMC7 transmembrane channel-like 7 1.70363
PNRC2 proline-rich nuclear receptor coactivator 2 1.69601
PHTF2 putative homeodomain transcription factor 2 1.69526
ABHD6 abhydrolase domain containing 6 1.69207
RAB3IP RAB3A interacting protein 1.6908
VTI1B vesicle transport through interaction with t-SNAREs 1B 1.68949
NLK nemo-like kinase 1.68616
MBD4 methyl-CpG binding domain protein 4 1.67907
PAX6 paired box 6 1.67537
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 1.67532
NKD2 naked cuticle homolog 2 (Drosophila) 1.6685
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1.66533
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 1.65993
MBD1 methyl-CpG binding domain protein 1 1.65569
AATF apoptosis antagonizing transcription factor 1.65363
CDK6 cyclin-dependent kinase 6 1.65326
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 1.64927
DEDD2 death effector domain containing 2 1.64151
TEX264 testis expressed 264 1.63736
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 1.63227
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.63045
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1.62706
RRM2 ribonucleotide reductase M2 1.62688
SH3BGRL SH3 domain binding glutamate-rich protein like 1.62586
RAB22A RAB22A, member RAS oncogene family 1.62124
GOLGA2 golgin A2 1.62045
LDLR low density lipoprotein receptor 1.6178
GPHN gephyrin 1.61658
SP1 Sp1 transcription factor 1.59745
PLXNC1 plexin C1 1.5933
USP47 ubiquitin specific peptidase 47 1.58974
WDR33 WD repeat domain 33 1.5883
VEZF1 vascular endothelial zinc finger 1 1.58501
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.57936
MKKS McKusick-Kaufman syndrome 1.57777
TRIM32 tripartite motif containing 32 1.57586
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.57375
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.56956
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 1.56846
TPMT thiopurine S-methyltransferase 1.56661
GRPEL2 GrpE-like 2, mitochondrial (E. coli) 1.56574
NEK6 NIMA-related kinase 6 1.55559
CRLF3 cytokine receptor-like factor 3 1.55217
EPOR erythropoietin receptor 1.55032
COG1 component of oligomeric golgi complex 1 1.54935
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.54695
NOL4 nucleolar protein 4 1.54555
EFS embryonal Fyn-associated substrate 1.54394
PANK4 pantothenate kinase 4 1.53775
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.53526
OR10Z1 olfactory receptor, family 10, subfamily Z, member 1 1.53288
C3ORF52 chromosome 3 open reading frame 52 1.5318
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 1.52991
DEDD death effector domain containing 1.52345
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.52101
NFE2 nuclear factor, erythroid 2 1.51927
PDE10A phosphodiesterase 10A 1.51917
SLC35E4 solute carrier family 35, member E4 1.50851
AURKC aurora kinase C 1.50778
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 1.50525
PEX12 peroxisomal biogenesis factor 12 1.50427
ITM2C integral membrane protein 2C 1.49923
MDM1 Mdm1 nuclear protein homolog (mouse) 1.49762
RNF4 ring finger protein 4 1.49608
RBP3 retinol binding protein 3, interstitial 1.49253
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 1.49058
SARS2 seryl-tRNA synthetase 2, mitochondrial 1.4899
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 1.48731
ALAD aminolevulinate dehydratase 1.48661
MELK maternal embryonic leucine zipper kinase 1.48501
CAPN10 calpain 10 1.48338
TRIM31 tripartite motif containing 31 1.4833
IL17RD interleukin 17 receptor D 1.47944
JAG1 jagged 1 1.47898
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 1.47658
HAPLN4 hyaluronan and proteoglycan link protein 4 1.47297
BAIAP2 BAI1-associated protein 2 1.4717
FZD3 frizzled class receptor 3 1.47077
EHD3 EH-domain containing 3 1.46901
CAMLG calcium modulating ligand 1.46644
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.46445
ARF5 ADP-ribosylation factor 5 1.45802
RAD51C RAD51 paralog C 1.45596
VIPR2 vasoactive intestinal peptide receptor 2 1.45508
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1.45271
CPOX coproporphyrinogen oxidase 1.45144
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 1.45065
SIM2 single-minded family bHLH transcription factor 2 1.44767
EGLN1 egl-9 family hypoxia-inducible factor 1 1.44729
RHOBTB2 Rho-related BTB domain containing 2 1.44697
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.4469
PPT1 palmitoyl-protein thioesterase 1 1.44565
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.44527
BCL6 B-cell CLL/lymphoma 6 1.44349
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 1.44055
CREG1 cellular repressor of E1A-stimulated genes 1 1.44002
TRIM59 tripartite motif containing 59 1.43993
GLI3 GLI family zinc finger 3 1.4391
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 1.43256
KCTD13 potassium channel tetramerization domain containing 13 1.42995
NEIL1 nei endonuclease VIII-like 1 (E. coli) 1.42219
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.42012
SLC17A2 solute carrier family 17, member 2 1.41569
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.41042
C16ORF74 chromosome 16 open reading frame 74 1.40999
FBXO7 F-box protein 7 1.40935
WEE1 WEE1 G2 checkpoint kinase 1.40795
DCK deoxycytidine kinase 1.40246
IDI1 isopentenyl-diphosphate delta isomerase 1 1.39829
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.39275
BECN1 beclin 1, autophagy related 1.39106
ATRNL1 attractin-like 1 1.38993
SOX1 SRY (sex determining region Y)-box 1 1.38943
MKRN1 makorin ring finger protein 1 1.38825
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.3876
LIMS1 LIM and senescent cell antigen-like domains 1 1.38742
EGLN3 egl-9 family hypoxia-inducible factor 3 1.38713
AARS alanyl-tRNA synthetase 1.38667
TXN2 thioredoxin 2 1.3857
NINJ2 ninjurin 2 1.3854
NKD1 naked cuticle homolog 1 (Drosophila) 1.38351
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 1.37966
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 1.37821
SNX10 sorting nexin 10 1.37787
PLEKHJ1 pleckstrin homology domain containing, family J member 1 1.37584
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 1.37509
UROD uroporphyrinogen decarboxylase 1.37231
GLMP glycosylated lysosomal membrane protein 1.37064
GOLGA7 golgin A7 1.37044
INSIG2 insulin induced gene 2 1.3703
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 1.36654
GMEB2 glucocorticoid modulatory element binding protein 2 1.36111
ACAT2 acetyl-CoA acetyltransferase 2 1.36068
SEPT6 septin 6 1.36003
PLAT plasminogen activator, tissue 1.35532
GANAB glucosidase, alpha; neutral AB 1.35424
LPIN2 lipin 2 1.3525
ZFX zinc finger protein, X-linked 1.34611
AFMID arylformamidase 1.34273
NICN1 nicolin 1 1.34246
PTPRM protein tyrosine phosphatase, receptor type, M 1.34182
SF3A1 splicing factor 3a, subunit 1, 120kDa 1.33908
LIMD1 LIM domains containing 1 1.33612

decreased expression

Symbol Name Standardized Value
WBSCR27 Williams Beuren syndrome chromosome region 27 -4.51632
SLURP1 secreted LY6/PLAUR domain containing 1 -3.79681
VPREB1 pre-B lymphocyte 1 -2.90253
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -2.62524
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 -2.5915
KIF5B kinesin family member 5B -2.53148
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta -2.39741
MMP14 matrix metallopeptidase 14 (membrane-inserted) -2.3566
ADAM32 ADAM metallopeptidase domain 32 -2.30137
OR13F1 olfactory receptor, family 13, subfamily F, member 1 -2.20671
CD109 CD109 molecule -2.17923
GPC6 glypican 6 -2.0997
CCL21 chemokine (C-C motif) ligand 21 -2.04618
GUCA2A guanylate cyclase activator 2A (guanylin) -2.01492
OR4K2 olfactory receptor, family 4, subfamily K, member 2 -2.00543
OR1L8 olfactory receptor, family 1, subfamily L, member 8 -1.98081
CCR4 chemokine (C-C motif) receptor 4 -1.97246
TCF4 transcription factor 4 -1.96577
NTF3 neurotrophin 3 -1.95951
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -1.92587
PCDHB11 protocadherin beta 11 -1.87569
UNC5C unc-5 homolog C (C. elegans) -1.83693
TUBG2 tubulin, gamma 2 -1.7941
MGST1 microsomal glutathione S-transferase 1 -1.75259
FEN1 flap structure-specific endonuclease 1 -1.74027
HIP1 huntingtin interacting protein 1 -1.74005
CDC23 cell division cycle 23 -1.73089
ELOVL3 ELOVL fatty acid elongase 3 -1.71624
MC5R melanocortin 5 receptor -1.69167
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 -1.67393
TPM3 tropomyosin 3 -1.65629
SSTR3 somatostatin receptor 3 -1.64832
RGS9 regulator of G-protein signaling 9 -1.63823
TDGF1 teratocarcinoma-derived growth factor 1 -1.61869
HPD 4-hydroxyphenylpyruvate dioxygenase -1.61075
ANKRD16 ankyrin repeat domain 16 -1.60565
SIX3 SIX homeobox 3 -1.57956
IL18BP interleukin 18 binding protein -1.57719
OR6C75 olfactory receptor, family 6, subfamily C, member 75 -1.57615
BCOR BCL6 corepressor -1.55913
SCNN1B sodium channel, non voltage gated 1 beta subunit -1.53331
TRIM17 tripartite motif containing 17 -1.52757
CLEC4M C-type lectin domain family 4, member M -1.51758
VILL villin-like -1.48277
CSNK1E casein kinase 1, epsilon -1.47085
SYNGR1 synaptogyrin 1 -1.46679
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -1.45896
GUCY2D guanylate cyclase 2D, membrane (retina-specific) -1.45668
DLX4 distal-less homeobox 4 -1.45316
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -1.45166
RNF24 ring finger protein 24 -1.44338
ADGRG2 adhesion G protein-coupled receptor G2 -1.43356
GRIK5 glutamate receptor, ionotropic, kainate 5 -1.41189
SDC3 syndecan 3 -1.38112
GPC5 glypican 5 -1.34789
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -1.34783
RPS20 ribosomal protein S20 -1.33548
AK2 adenylate kinase 2 -1.32335
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides -1.31961
VGLL4 vestigial-like family member 4 -1.3187
OR4C46 olfactory receptor, family 4, subfamily C, member 46 -1.29824
NKX2-3 NK2 homeobox 3 -1.29771
PAX4 paired box 4 -1.29598
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -1.29159
KLHL18 kelch-like family member 18 -1.28634
TRPC7 transient receptor potential cation channel, subfamily C, member 7 -1.26955
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -1.26902
RPS11 ribosomal protein S11 -1.24183
OR13A1 olfactory receptor, family 13, subfamily A, member 1 -1.22204
GNMT glycine N-methyltransferase -1.21019
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -1.19502
FMO3 flavin containing monooxygenase 3 -1.19321
TMEM14A transmembrane protein 14A -1.17272
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -1.15322
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -1.14043
NR4A2 nuclear receptor subfamily 4, group A, member 2 -1.14022
MSC musculin -1.13958
ACIN1 apoptotic chromatin condensation inducer 1 -1.13922
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 -1.13176
TAS2R39 taste receptor, type 2, member 39 -1.12932
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 -1.12145
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -1.12099
CRISP2 cysteine-rich secretory protein 2 -1.10245
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -1.09845
APAF1 apoptotic peptidase activating factor 1 -1.09717
SESN2 sestrin 2 -1.09098
LDB2 LIM domain binding 2 -1.09091
UNC119 unc-119 homolog (C. elegans) -1.08548
RIMS2 regulating synaptic membrane exocytosis 2 -1.08132
SYT3 synaptotagmin III -1.0738
CHRM2 cholinergic receptor, muscarinic 2 -1.07094
TPT1 tumor protein, translationally-controlled 1 -1.06446
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 -1.0539
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -1.04019
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -1.03666
GIF gastric intrinsic factor (vitamin B synthesis) -1.02757
ARHGAP4 Rho GTPase activating protein 4 -1.01254
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 -1.01242
LZTS2 leucine zipper, putative tumor suppressor 2 -1.00795
OR2AP1 olfactory receptor, family 2, subfamily AP, member 1 -1.00724
HPCAL1 hippocalcin-like 1 -1.00652
ADGRB2 adhesion G protein-coupled receptor B2 -1.00568
C12ORF57 chromosome 12 open reading frame 57 -0.998817
PCDHB2 protocadherin beta 2 -0.997658
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 -0.997228
GRIK2 glutamate receptor, ionotropic, kainate 2 -0.988997
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.988875
FXYD7 FXYD domain containing ion transport regulator 7 -0.983545
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -0.9767
POU6F1 POU class 6 homeobox 1 -0.976429
RPL37 ribosomal protein L37 -0.965181
TRIB1 tribbles pseudokinase 1 -0.961755
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.961384
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 -0.954872
C22ORF23 chromosome 22 open reading frame 23 -0.95411
TLR9 toll-like receptor 9 -0.952966
CRTAM cytotoxic and regulatory T cell molecule -0.936145
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -0.931379
CNR2 cannabinoid receptor 2 (macrophage) -0.930589
AMOTL2 angiomotin like 2 -0.930075
BTLA B and T lymphocyte associated -0.929988
DISC1 disrupted in schizophrenia 1 -0.925152
PRG3 proteoglycan 3 -0.920571
FGD2 FYVE, RhoGEF and PH domain containing 2 -0.918368
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) -0.917056
PADI6 peptidyl arginine deiminase, type VI -0.917007
LRRC10 leucine rich repeat containing 10 -0.916705
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.915499
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.914631
KCNK4 potassium channel, two pore domain subfamily K, member 4 -0.913283
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.913108
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -0.911352
MSH5 mutS homolog 5 -0.910903
THRB thyroid hormone receptor, beta -0.910564
SLC39A3 solute carrier family 39 (zinc transporter), member 3 -0.910426
OR1S1 olfactory receptor, family 1, subfamily S, member 1 (gene/pseudogene) -0.903463
OR52D1 olfactory receptor, family 52, subfamily D, member 1 -0.902196
ILF3 interleukin enhancer binding factor 3, 90kDa -0.900738
E4F1 E4F transcription factor 1 -0.900284
TRIM47 tripartite motif containing 47 -0.896241
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.895939
ANKRD23 ankyrin repeat domain 23 -0.892909
MRPL39 mitochondrial ribosomal protein L39 -0.887325
REG1A regenerating islet-derived 1 alpha -0.881969
BRD2 bromodomain containing 2 -0.880453
GKAP1 G kinase anchoring protein 1 -0.87976
SELE selectin E -0.879646
FBXW8 F-box and WD repeat domain containing 8 -0.876504
C9ORF172 chromosome 9 open reading frame 172 -0.874679
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.873597
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 -0.872647
GAB3 GRB2-associated binding protein 3 -0.865391
OR2A25 olfactory receptor, family 2, subfamily A, member 25 -0.863443
PLCD3 phospholipase C, delta 3 -0.863267
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 -0.861258
CSPG4 chondroitin sulfate proteoglycan 4 -0.856621
OMP olfactory marker protein -0.855811
MYH9 myosin, heavy chain 9, non-muscle -0.847104
TRIM28 tripartite motif containing 28 -0.846499
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.843759
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -0.842959
VEGFB vascular endothelial growth factor B -0.840307
NTSR1 neurotensin receptor 1 (high affinity) -0.839679
STRN4 striatin, calmodulin binding protein 4 -0.839136
GARNL3 GTPase activating Rap/RanGAP domain-like 3 -0.836775
EPX eosinophil peroxidase -0.831832
ATOH8 atonal homolog 8 (Drosophila) -0.831675
MRGPRF MAS-related GPR, member F -0.829053
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 -0.828974
NFE2L3 nuclear factor, erythroid 2-like 3 -0.823483
NRL neural retina leucine zipper -0.822547
TACR3 tachykinin receptor 3 -0.822426
PLK3 polo-like kinase 3 -0.822352
OR4D6 olfactory receptor, family 4, subfamily D, member 6 -0.822282
PCDHB15 protocadherin beta 15 -0.820018
RTN3 reticulon 3 -0.81791
OR2D3 olfactory receptor, family 2, subfamily D, member 3 -0.817545
OR51I2 olfactory receptor, family 51, subfamily I, member 2 -0.815912
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.81353
MRPS18A mitochondrial ribosomal protein S18A -0.812952
FGF6 fibroblast growth factor 6 -0.811448
CDK10 cyclin-dependent kinase 10 -0.811046
OR51I1 olfactory receptor, family 51, subfamily I, member 1 -0.810816
IQSEC2 IQ motif and Sec7 domain 2 -0.809642
TCL1A T-cell leukemia/lymphoma 1A -0.809368
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -0.809006
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -0.802908
COASY CoA synthase -0.801701
OAZ1 ornithine decarboxylase antizyme 1 -0.80042
C14ORF79 chromosome 14 open reading frame 79 -0.798844
WBP4 WW domain binding protein 4 -0.795449
TLE2 transducin-like enhancer of split 2 -0.794977
RPL22 ribosomal protein L22 -0.7945
XPO7 exportin 7 -0.792769
CD163 CD163 molecule -0.792204
RAB13 RAB13, member RAS oncogene family -0.791978
CCL13 chemokine (C-C motif) ligand 13 -0.788996
CETN1 centrin, EF-hand protein, 1 -0.787929
IL23A interleukin 23, alpha subunit p19 -0.785729
TTYH1 tweety family member 1 -0.785635
ASB18 ankyrin repeat and SOCS box containing 18 -0.783284
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa -0.781087
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -0.780965
PCDHB6 protocadherin beta 6 -0.778164
OR56A5 olfactory receptor, family 56, subfamily A, member 5 -0.774269
BTF3 basic transcription factor 3 -0.768129
MMP17 matrix metallopeptidase 17 (membrane-inserted) -0.766672
OMG oligodendrocyte myelin glycoprotein -0.766077
RASGEF1B RasGEF domain family, member 1B -0.760735
TRAPPC5 trafficking protein particle complex 5 -0.760182
GCA grancalcin, EF-hand calcium binding protein -0.758955
DLX5 distal-less homeobox 5 -0.758648
PHC3 polyhomeotic homolog 3 (Drosophila) -0.758087
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 -0.75703
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -0.756912
RNF31 ring finger protein 31 -0.752655
FGF11 fibroblast growth factor 11 -0.75263
MUSK muscle, skeletal, receptor tyrosine kinase -0.751521
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -0.751076
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.749335
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -0.748864
C11ORF94 chromosome 11 open reading frame 94 -0.74776
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.745911
OR5P2 olfactory receptor, family 5, subfamily P, member 2 -0.744529
FOXD2 forkhead box D2 -0.743486
SNX9 sorting nexin 9 -0.743364
RYR2 ryanodine receptor 2 (cardiac) -0.742546
IRF4 interferon regulatory factor 4 -0.741055
MBP myelin basic protein -0.740198
NTAN1 N-terminal asparagine amidase -0.737546
MEFV Mediterranean fever -0.73747
CRX cone-rod homeobox -0.733302
OR5D16 olfactory receptor, family 5, subfamily D, member 16 -0.731735
CAPS2 calcyphosine 2 -0.731137
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.730775
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -0.727767
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -0.727628
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) -0.725453
PPIE peptidylprolyl isomerase E (cyclophilin E) -0.724911
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.724181
KATNAL1 katanin p60 subunit A-like 1 -0.723291
ASB10 ankyrin repeat and SOCS box containing 10 -0.722138
MAEA macrophage erythroblast attacher -0.720266
GPI glucose-6-phosphate isomerase -0.71997
TNMD tenomodulin -0.717065
CD244 CD244 molecule, natural killer cell receptor 2B4 -0.716956
NPTX2 neuronal pentraxin II -0.712529
OR51S1 olfactory receptor, family 51, subfamily S, member 1 -0.710574
TAS2R7 taste receptor, type 2, member 7 -0.709378
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.708399
MEI1 meiosis inhibitor 1 -0.707986
OR10A4 olfactory receptor, family 10, subfamily A, member 4 -0.707872
HDGFRP2 hepatoma-derived growth factor-related protein 2 -0.707728
MYH14 myosin, heavy chain 14, non-muscle -0.707389
FGF16 fibroblast growth factor 16 -0.705353
KIAA0825 KIAA0825 -0.704511
PELI1 pellino E3 ubiquitin protein ligase 1 -0.704183
CTPS2 CTP synthase 2 -0.704176
CBX4 chromobox homolog 4 -0.704087
STK35 serine/threonine kinase 35 -0.702772
OR5K1 olfactory receptor, family 5, subfamily K, member 1 -0.702455
OR51B6 olfactory receptor, family 51, subfamily B, member 6 -0.700473
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha -0.700172
E2F1 E2F transcription factor 1 -0.700122
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.698927
FOXO3 forkhead box O3 -0.698456
TP63 tumor protein p63 -0.697915
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.696153
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 -0.695264
FIGLA folliculogenesis specific basic helix-loop-helix -0.693147
USP29 ubiquitin specific peptidase 29 -0.691537
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -0.689986
BAAT bile acid CoA:amino acid N-acyltransferase -0.689307
ADGRE5 adhesion G protein-coupled receptor E5 -0.686558
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.686407
COL9A3 collagen, type IX, alpha 3 -0.685479
MRVI1 murine retrovirus integration site 1 homolog -0.682605
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.682181
COG4 component of oligomeric golgi complex 4 -0.68189
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -0.680902
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.680749
NCOR2 nuclear receptor corepressor 2 -0.678039
ZNF296 zinc finger protein 296 -0.677812
ST5 suppression of tumorigenicity 5 -0.677061
MAMDC2 MAM domain containing 2 -0.676501
RPS10 ribosomal protein S10 -0.676371
TCERG1 transcription elongation regulator 1 -0.675404
NUP93 nucleoporin 93kDa -0.67538
PIAS3 protein inhibitor of activated STAT, 3 -0.675334
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.674599
SEPT9 septin 9 -0.673743
KCNK12 potassium channel, two pore domain subfamily K, member 12 -0.670791
DNASE1L3 deoxyribonuclease I-like 3 -0.670627
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -0.669543
EYA1 EYA transcriptional coactivator and phosphatase 1 -0.664606
STK32B serine/threonine kinase 32B -0.664409
FIGF c-fos induced growth factor (vascular endothelial growth factor D) -0.662232
KLK7 kallikrein-related peptidase 7 -0.661512
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.661204
CHM choroideremia (Rab escort protein 1) -0.661035