Granulomatous Disease, Chronic_Blood neutrophil_GSE935 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE935
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Genes

600 genes differentially expressed during Granulomatous Disease, Chronic_Blood neutrophil_GSE935 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
CLDN4 claudin 4 3.13924
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 2.81801
SAT1 spermidine/spermine N1-acetyltransferase 1 2.78815
ARHGAP4 Rho GTPase activating protein 4 2.77953
CLCN1 chloride channel, voltage-sensitive 1 2.75179
MCF2L MCF.2 cell line derived transforming sequence-like 2.7168
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 2.65355
SLC38A3 solute carrier family 38, member 3 2.64879
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.64219
CTSZ cathepsin Z 2.61159
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 2.58927
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 2.57859
SMG6 SMG6 nonsense mediated mRNA decay factor 2.52778
HLA-A major histocompatibility complex, class I, A 2.51452
LTA lymphotoxin alpha 2.51359
KLK13 kallikrein-related peptidase 13 2.47256
HPN hepsin 2.45669
HLA-E major histocompatibility complex, class I, E 2.43827
CDK13 cyclin-dependent kinase 13 2.40078
PLTP phospholipid transfer protein 2.35846
FLOT1 flotillin 1 2.35109
CALCA calcitonin-related polypeptide alpha 2.32305
B2M beta-2-microglobulin 2.31402
ADGRL2 adhesion G protein-coupled receptor L2 2.29735
SAG S-antigen; retina and pineal gland (arrestin) 2.28871
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 2.27763
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 2.27315
PTGER3 prostaglandin E receptor 3 (subtype EP3) 2.26082
ACTG1 actin gamma 1 2.25213
CAPN5 calpain 5 2.22669
LAD1 ladinin 1 2.21674
HABP2 hyaluronan binding protein 2 2.21181
MPZ myelin protein zero 2.21008
TERT telomerase reverse transcriptase 2.2091
PARP3 poly (ADP-ribose) polymerase family, member 3 2.20843
SNUPN snurportin 1 2.19057
CTSK cathepsin K 2.19037
ARID1A AT rich interactive domain 1A (SWI-like) 2.18309
PLAGL1 pleiomorphic adenoma gene-like 1 2.18123
ZNF593 zinc finger protein 593 2.17776
HLA-F major histocompatibility complex, class I, F 2.1647
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.16114
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.15412
CDK5 cyclin-dependent kinase 5 2.15304
LYPLA2 lysophospholipase II 2.14438
ACTB actin, beta 2.14052
FLT3LG fms-related tyrosine kinase 3 ligand 2.13227
PRCP prolylcarboxypeptidase (angiotensinase C) 2.12922
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.12697
CDH4 cadherin 4, type 1, R-cadherin (retinal) 2.11377
GMDS GDP-mannose 4,6-dehydratase 2.11298
CLIC1 chloride intracellular channel 1 2.10941
NCKAP1L NCK-associated protein 1-like 2.10717
NTSR1 neurotensin receptor 1 (high affinity) 2.10585
CTRC chymotrypsin C (caldecrin) 2.10133
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2.09467
ECE2 endothelin converting enzyme 2 2.09201
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.08798
RAB3A RAB3A, member RAS oncogene family 2.08292
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 2.0762
ETHE1 ethylmalonic encephalopathy 1 2.0704
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.05608
MRPL12 mitochondrial ribosomal protein L12 2.05335
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 2.04983
COL9A1 collagen, type IX, alpha 1 2.04946
ALOX15B arachidonate 15-lipoxygenase, type B 2.04654
UTF1 undifferentiated embryonic cell transcription factor 1 2.03992
PVALB parvalbumin 2.03962
KAT2A K(lysine) acetyltransferase 2A 1.99991
FTL ferritin, light polypeptide 1.97952
MRPS12 mitochondrial ribosomal protein S12 1.97546
TYMP thymidine phosphorylase 1.97397
DPF1 D4, zinc and double PHD fingers family 1 1.97277
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 1.97118
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.96615
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.96532
S100A11 S100 calcium binding protein A11 1.96158
LST1 leukocyte specific transcript 1 1.95754
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.95638
EPHA7 EPH receptor A7 1.95549
MRPL28 mitochondrial ribosomal protein L28 1.94951
GLUL glutamate-ammonia ligase 1.94459
RAD54L2 RAD54-like 2 (S. cerevisiae) 1.932
OPLAH 5-oxoprolinase (ATP-hydrolysing) 1.91969
CSDC2 cold shock domain containing C2, RNA binding 1.91872
IFITM1 interferon induced transmembrane protein 1 1.91299
TYROBP TYRO protein tyrosine kinase binding protein 1.90663
CHMP1A charged multivesicular body protein 1A 1.90482
SLA Src-like-adaptor 1.90051
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 1.89747
TOR1A torsin family 1, member A (torsin A) 1.89705
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 1.89244
TMSB4X thymosin beta 4, X-linked 1.88451
HYAL1 hyaluronoglucosaminidase 1 1.87372
DMWD dystrophia myotonica, WD repeat containing 1.86283
LYZ lysozyme 1.86265
S100A9 S100 calcium binding protein A9 1.85987
MFAP3 microfibrillar-associated protein 3 1.85857
NREP neuronal regeneration related protein 1.85488
SLC10A3 solute carrier family 10, member 3 1.84976
CALCR calcitonin receptor 1.84617
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 1.84404
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.84154
RGS2 regulator of G-protein signaling 2 1.83603
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.8223
OGFR opioid growth factor receptor 1.81916
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.81839
ADAM8 ADAM metallopeptidase domain 8 1.81702
TGOLN2 trans-golgi network protein 2 1.81032
ADRA2A adrenoceptor alpha 2A 1.80437
MASP2 mannan-binding lectin serine peptidase 2 1.80429
GAMT guanidinoacetate N-methyltransferase 1.79239
CDX1 caudal type homeobox 1 1.78076
OAZ1 ornithine decarboxylase antizyme 1 1.77717
KRT17 keratin 17, type I 1.77339
C9ORF114 chromosome 9 open reading frame 114 1.77211
ACAA1 acetyl-CoA acyltransferase 1 1.7602
LAPTM5 lysosomal protein transmembrane 5 1.75596
CKB creatine kinase, brain 1.75314
MYBPC1 myosin binding protein C, slow type 1.74974
STARD3 StAR-related lipid transfer (START) domain containing 3 1.74575
ZMYM4 zinc finger, MYM-type 4 1.7447
FMNL1 formin-like 1 1.73193
HIC1 hypermethylated in cancer 1 1.72179
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.72144
MTTP microsomal triglyceride transfer protein 1.72061
PRM1 protamine 1 1.71794
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 1.71324
CASP10 caspase 10, apoptosis-related cysteine peptidase 1.71058
S100A8 S100 calcium binding protein A8 1.71024
PRAMEF12 PRAME family member 12 1.7079
SCGB1D2 secretoglobin, family 1D, member 2 1.7035
ELN elastin 1.70323
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.68807
AGPS alkylglycerone phosphate synthase 1.68784
CD96 CD96 molecule 1.68698
MB myoglobin 1.68635
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.68608
GPAA1 glycosylphosphatidylinositol anchor attachment 1 1.68277
OAZ3 ornithine decarboxylase antizyme 3 1.67992
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.67847
EBF1 early B-cell factor 1 1.67802
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.67512
MPDU1 mannose-P-dolichol utilization defect 1 1.67222
IL10RB interleukin 10 receptor, beta 1.66889
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.66453
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.66388
PDAP1 PDGFA associated protein 1 1.66276
ANK1 ankyrin 1, erythrocytic 1.66211
PLA2G10 phospholipase A2, group X 1.65757
CST2 cystatin SA 1.65423
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 1.6529
CREBBP CREB binding protein 1.64518
AIM2 absent in melanoma 2 1.64401
GNG5 guanine nucleotide binding protein (G protein), gamma 5 1.64302
RHOA ras homolog family member A 1.63617
HMGB2 high mobility group box 2 1.6361
TRPM2 transient receptor potential cation channel, subfamily M, member 2 1.63278
CHPF chondroitin polymerizing factor 1.6285
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 1.62117
NOTCH2 notch 2 1.61975
JTB jumping translocation breakpoint 1.61694
MYO7A myosin VIIA 1.61204
STX1A syntaxin 1A (brain) 1.61163
MAPKAP1 mitogen-activated protein kinase associated protein 1 1.6063
HMGN2 high mobility group nucleosomal binding domain 2 1.60456
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.59998
QPRT quinolinate phosphoribosyltransferase 1.59484
TPPP tubulin polymerization promoting protein 1.59346
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 1.59213
ELF5 E74-like factor 5 (ets domain transcription factor) 1.59066
ZNRD1-AS1 ZNRD1 antisense RNA 1 1.58862
WASL Wiskott-Aldrich syndrome-like 1.58848
TMED1 transmembrane emp24 protein transport domain containing 1 1.58733
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.58436
IER2 immediate early response 2 1.58235
GFRA3 GDNF family receptor alpha 3 1.57664
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1.57508
PRKCD protein kinase C, delta 1.5728
SAMD14 sterile alpha motif domain containing 14 1.57009
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 1.56607
SMA4 glucuronidase, beta pseudogene 1.56558
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 1.56536
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 1.56516
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 1.56429
TEX28 testis expressed 28 1.56128
IQCK IQ motif containing K 1.55917
VENTX VENT homeobox 1.5574
ATF6B activating transcription factor 6 beta 1.55133
FOXM1 forkhead box M1 1.55108
TGM4 transglutaminase 4 1.54711
MAP2K2 mitogen-activated protein kinase kinase 2 1.5419
LIG3 ligase III, DNA, ATP-dependent 1.53894
HNF4A hepatocyte nuclear factor 4, alpha 1.53791
COL6A1 collagen, type VI, alpha 1 1.53694
HCRTR1 hypocretin (orexin) receptor 1 1.5367
PTPRH protein tyrosine phosphatase, receptor type, H 1.53535
MAST2 microtubule associated serine/threonine kinase 2 1.53107
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.53091
TRIOBP TRIO and F-actin binding protein 1.52176
MUC1 mucin 1, cell surface associated 1.52154
NT5E 5'-nucleotidase, ecto (CD73) 1.51846
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.51658
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.51532
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 1.51178
EPRS glutamyl-prolyl-tRNA synthetase 1.51053
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 1.50929
SYT2 synaptotagmin II 1.50913
FOXN1 forkhead box N1 1.50718
AURKB aurora kinase B 1.50544
PDCD2 programmed cell death 2 1.50453
TBX6 T-box 6 1.50329
RPL3L ribosomal protein L3-like 1.50219
ICOSLG inducible T-cell co-stimulator ligand 1.50184
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 1.50107
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.49914
EIF6 eukaryotic translation initiation factor 6 1.49645
DKFZP434A062 uncharacterized LOC26102 1.49492
CRTC1 CREB regulated transcription coactivator 1 1.49109
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 1.49011
THBS1 thrombospondin 1 1.48908
RPS9 ribosomal protein S9 1.48618
NQO2 NAD(P)H dehydrogenase, quinone 2 1.48437
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.48388
CELP carboxyl ester lipase pseudogene 1.48351
RORC RAR-related orphan receptor C 1.48298
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.48093
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1.47711
C6ORF120 chromosome 6 open reading frame 120 1.47049
PPL periplakin 1.47048
NMBR neuromedin B receptor 1.46879
KRT8 keratin 8, type II 1.4682
PLCG1 phospholipase C, gamma 1 1.46746
GCK glucokinase (hexokinase 4) 1.46695
MMP17 matrix metallopeptidase 17 (membrane-inserted) 1.46299
ARSD arylsulfatase D 1.46248
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 1.45799
CD5L CD5 molecule-like 1.45551
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 1.45426
MT1B metallothionein 1B 1.45314
TCF15 transcription factor 15 (basic helix-loop-helix) 1.45208
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.45021
THEMIS2 thymocyte selection associated family member 2 1.44575
PCDHA3 protocadherin alpha 3 1.44492
CPT1B carnitine palmitoyltransferase 1B (muscle) 1.44368
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.44115
TNK2 tyrosine kinase, non-receptor, 2 1.44069
ABHD14A abhydrolase domain containing 14A 1.43775
ASIC3 acid sensing (proton gated) ion channel 3 1.43735
ARG2 arginase 2 1.43684
PTPRS protein tyrosine phosphatase, receptor type, S 1.43663
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.43224
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 1.43107
SOX3 SRY (sex determining region Y)-box 3 1.4267
MFSD7 major facilitator superfamily domain containing 7 1.41768
HRAS Harvey rat sarcoma viral oncogene homolog 1.41514
MAN1A1 mannosidase, alpha, class 1A, member 1 1.41465
PKLR pyruvate kinase, liver and RBC 1.41007
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 1.40994
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 1.40703
CCDC85B coiled-coil domain containing 85B 1.40487
MYL12B myosin, light chain 12B, regulatory 1.40402
CYBA cytochrome b-245, alpha polypeptide 1.40161
KDM5A lysine (K)-specific demethylase 5A 1.39576
OR2F2 olfactory receptor, family 2, subfamily F, member 2 1.39293
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 1.39233
ITM2B integral membrane protein 2B 1.38955
MAEA macrophage erythroblast attacher 1.38712
TOX3 TOX high mobility group box family member 3 1.38344
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 1.38265
HSPA4 heat shock 70kDa protein 4 1.37939
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.37806
BCL2L1 BCL2-like 1 1.3744
STK11 serine/threonine kinase 11 1.37166
DAO D-amino-acid oxidase 1.36975
FOXC2 forkhead box C2 1.35947
WNT8B wingless-type MMTV integration site family, member 8B 1.3589
MET MET proto-oncogene, receptor tyrosine kinase 1.35609
DRG2 developmentally regulated GTP binding protein 2 1.35305
SLPI secretory leukocyte peptidase inhibitor 1.35208
CYC1 cytochrome c-1 1.35096
C16ORF62 chromosome 16 open reading frame 62 1.35063
ADRB3 adrenoceptor beta 3 1.35017
LOC728093 putative POM121-like protein 1-like 1.34867
CSPG4 chondroitin sulfate proteoglycan 4 1.3486
TADA2A transcriptional adaptor 2A 1.34729
SCRIB scribbled planar cell polarity protein 1.34659
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 1.34603
HLA-DMA major histocompatibility complex, class II, DM alpha 1.34581
RGS19 regulator of G-protein signaling 19 1.344
LBR lamin B receptor 1.3439
UBC ubiquitin C 1.3433
COL1A2 collagen, type I, alpha 2 1.34262
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.34232
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.34197
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.34035
GGT5 gamma-glutamyltransferase 5 1.33713
CORO1A coronin, actin binding protein, 1A 1.33708
CARD8 caspase recruitment domain family, member 8 1.33657
LMAN2 lectin, mannose-binding 2 1.33435

decreased expression

Symbol Name Standardized Value
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -3.17237
POGZ pogo transposable element with ZNF domain -3.10189
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -3.06879
UBE2I ubiquitin-conjugating enzyme E2I -3.06234
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.99896
TRA2A transformer 2 alpha homolog (Drosophila) -2.94835
N4BP2L1 NEDD4 binding protein 2-like 1 -2.8699
MAN2C1 mannosidase, alpha, class 2C, member 1 -2.80448
PRPF8 pre-mRNA processing factor 8 -2.7835
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.738
FNBP4 formin binding protein 4 -2.66007
RAN RAN, member RAS oncogene family -2.65472
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.65146
IL13RA1 interleukin 13 receptor, alpha 1 -2.64934
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -2.64003
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.6095
NONO non-POU domain containing, octamer-binding -2.59147
BTD biotinidase -2.55835
CPNE1 copine I -2.55626
YTHDC1 YTH domain containing 1 -2.54205
SF3A1 splicing factor 3a, subunit 1, 120kDa -2.53649
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -2.50964
IDS iduronate 2-sulfatase -2.48066
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.47794
PRRC2C proline-rich coiled-coil 2C -2.47169
BUB3 BUB3 mitotic checkpoint protein -2.46105
IST1 increased sodium tolerance 1 homolog (yeast) -2.43067
CTBP1 C-terminal binding protein 1 -2.42993
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -2.42617
AHCYL1 adenosylhomocysteinase-like 1 -2.42574
AKAP17A A kinase (PRKA) anchor protein 17A -2.40015
SMG7 SMG7 nonsense mediated mRNA decay factor -2.39161
PLXNB2 plexin B2 -2.39021
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.38208
RNPS1 RNA binding protein S1, serine-rich domain -2.38191
UBXN7 UBX domain protein 7 -2.37966
ZNF91 zinc finger protein 91 -2.36401
TUG1 taurine up-regulated 1 (non-protein coding) -2.35363
GLG1 golgi glycoprotein 1 -2.34104
BRD4 bromodomain containing 4 -2.33888
METAP1 methionyl aminopeptidase 1 -2.32238
SLC31A2 solute carrier family 31 (copper transporter), member 2 -2.32043
ASNS asparagine synthetase (glutamine-hydrolyzing) -2.31543
ING3 inhibitor of growth family, member 3 -2.3138
EWSR1 EWS RNA-binding protein 1 -2.29654
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -2.26855
CDKL5 cyclin-dependent kinase-like 5 -2.26102
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.2568
ANXA11 annexin A11 -2.25043
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -2.24668
MAPRE3 microtubule-associated protein, RP/EB family, member 3 -2.24564
AQP2 aquaporin 2 (collecting duct) -2.24422
TULP3 tubby like protein 3 -2.23961
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -2.23835
KLF5 Kruppel-like factor 5 (intestinal) -2.2373
ZNHIT3 zinc finger, HIT-type containing 3 -2.23552
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -2.22364
PRPF3 pre-mRNA processing factor 3 -2.21344
PRCC papillary renal cell carcinoma (translocation-associated) -2.20888
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.20346
SRSF6 serine/arginine-rich splicing factor 6 -2.19697
GSTP1 glutathione S-transferase pi 1 -2.19659
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -2.19416
RAB6A RAB6A, member RAS oncogene family -2.19113
SON SON DNA binding protein -2.19107
EI24 etoposide induced 2.4 -2.1894
U2AF2 U2 small nuclear RNA auxiliary factor 2 -2.189
STAU1 staufen double-stranded RNA binding protein 1 -2.18408
SRSF7 serine/arginine-rich splicing factor 7 -2.18358
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -2.18198
HIPK3 homeodomain interacting protein kinase 3 -2.17965
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -2.17956
PABPN1 poly(A) binding protein, nuclear 1 -2.17738
C5ORF30 chromosome 5 open reading frame 30 -2.17316
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -2.16256
CTBS chitobiase, di-N-acetyl- -2.15738
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -2.15574
RXRB retinoid X receptor, beta -2.14731
RBM5 RNA binding motif protein 5 -2.13695
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) -2.12455
HIPK1 homeodomain interacting protein kinase 1 -2.12061
MMP25 matrix metallopeptidase 25 -2.11996
ZNF266 zinc finger protein 266 -2.11772
FAAH fatty acid amide hydrolase -2.10179
SPATA2 spermatogenesis associated 2 -2.09853
TOX4 TOX high mobility group box family member 4 -2.09536
PUM2 pumilio RNA-binding family member 2 -2.08878
CCNI cyclin I -2.08472
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -2.08295
BTNL3 butyrophilin-like 3 -2.0691
RLF rearranged L-myc fusion -2.06687
PUF60 poly-U binding splicing factor 60KDa -2.05356
ABAT 4-aminobutyrate aminotransferase -2.04803
ADGRE2 adhesion G protein-coupled receptor E2 -2.03414
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B -2.02779
PCBP2 poly(rC) binding protein 2 -2.02684
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.01885
CASC3 cancer susceptibility candidate 3 -2.01475
KAT6A K(lysine) acetyltransferase 6A -2.00714
MCRS1 microspherule protein 1 -2.00607
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.00305
SRSF10 serine/arginine-rich splicing factor 10 -1.99529
KDM5C lysine (K)-specific demethylase 5C -1.99505
TRIM37 tripartite motif containing 37 -1.99162
TYK2 tyrosine kinase 2 -1.98377
DLG5 discs, large homolog 5 (Drosophila) -1.97363
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -1.97073
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -1.96985
NUP153 nucleoporin 153kDa -1.96296
RPL11 ribosomal protein L11 -1.96206
SAFB2 scaffold attachment factor B2 -1.95942
SERINC5 serine incorporator 5 -1.95929
JRK Jrk homolog (mouse) -1.95902
ENSA endosulfine alpha -1.95526
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -1.95472
PYGB phosphorylase, glycogen; brain -1.95325
EIF4B eukaryotic translation initiation factor 4B -1.93732
LIG4 ligase IV, DNA, ATP-dependent -1.93597
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -1.93478
PTBP3 polypyrimidine tract binding protein 3 -1.92808
NAP1L4 nucleosome assembly protein 1-like 4 -1.91709
TRAPPC2P1 -1.91706
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.91691
GSPT1 G1 to S phase transition 1 -1.91664
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.91381
TXLNA taxilin alpha -1.91015
CHERP calcium homeostasis endoplasmic reticulum protein -1.90361
BAZ2B bromodomain adjacent to zinc finger domain, 2B -1.90314
AP2B1 adaptor-related protein complex 2, beta 1 subunit -1.902
ZMYM2 zinc finger, MYM-type 2 -1.89933
MFAP1 microfibrillar-associated protein 1 -1.89728
RAD1 RAD1 checkpoint DNA exonuclease -1.89676
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -1.8933
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -1.88958
USP19 ubiquitin specific peptidase 19 -1.88747
CDC34 cell division cycle 34 -1.88303
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -1.86186
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -1.85297
WHSC1 Wolf-Hirschhorn syndrome candidate 1 -1.85016
SNW1 SNW domain containing 1 -1.8501
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 -1.85001
EP400 E1A binding protein p400 -1.84834
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -1.84356
FPR2 formyl peptide receptor 2 -1.84167
ARF3 ADP-ribosylation factor 3 -1.83806
COPE coatomer protein complex, subunit epsilon -1.83272
ACTL6A actin-like 6A -1.82628
RSRC2 arginine/serine-rich coiled-coil 2 -1.8251
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -1.82485
FBXO46 F-box protein 46 -1.82213
MBD2 methyl-CpG binding domain protein 2 -1.81766
APOA2 apolipoprotein A-II -1.81614
RPS13 ribosomal protein S13 -1.81552
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -1.81532
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -1.81172
SKI SKI proto-oncogene -1.81154
NUP62 nucleoporin 62kDa -1.80639
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.78645
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.78563
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -1.78231
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -1.78179
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -1.78036
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -1.78011
FAM168B family with sequence similarity 168, member B -1.77515
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -1.77289
MXRA7 matrix-remodelling associated 7 -1.77228
PIAS1 protein inhibitor of activated STAT, 1 -1.77013
DENND3 DENN/MADD domain containing 3 -1.76868
HNRNPR heterogeneous nuclear ribonucleoprotein R -1.76757
SEC23IP SEC23 interacting protein -1.76724
PRPH peripherin -1.76184
GOSR1 golgi SNAP receptor complex member 1 -1.75887
TCF25 transcription factor 25 (basic helix-loop-helix) -1.75725
UBXN4 UBX domain protein 4 -1.75525
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -1.74517
IP6K1 inositol hexakisphosphate kinase 1 -1.74337
GAA glucosidase, alpha; acid -1.73901
NUPL1 nucleoporin like 1 -1.73373
WIPF1 WAS/WASL interacting protein family, member 1 -1.73356
ZNF134 zinc finger protein 134 -1.73288
VDAC2 voltage-dependent anion channel 2 -1.7316
OSGIN2 oxidative stress induced growth inhibitor family member 2 -1.72588
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -1.72518
RUVBL2 RuvB-like AAA ATPase 2 -1.723
SMC4 structural maintenance of chromosomes 4 -1.72207
SRRM2 serine/arginine repetitive matrix 2 -1.72071
SART3 squamous cell carcinoma antigen recognized by T cells 3 -1.71976
UBA2 ubiquitin-like modifier activating enzyme 2 -1.71898
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -1.71246
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa -1.70942
MTMR3 myotubularin related protein 3 -1.70757
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -1.70628
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -1.70419
AHCTF1 AT hook containing transcription factor 1 -1.70221
COX4I1 cytochrome c oxidase subunit IV isoform 1 -1.70192
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.70084
CTDNEP1 CTD nuclear envelope phosphatase 1 -1.69233
ZNF200 zinc finger protein 200 -1.6879
NPHP4 nephronophthisis 4 -1.68018
PVRL3 poliovirus receptor-related 3 -1.67893
PABPC1 poly(A) binding protein, cytoplasmic 1 -1.67424
ATM ATM serine/threonine kinase -1.67411
PNISR PNN-interacting serine/arginine-rich protein -1.67343
ZNF274 zinc finger protein 274 -1.67304
IGF2R insulin-like growth factor 2 receptor -1.67245
CFD complement factor D (adipsin) -1.67099
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -1.66889
COX20 COX20 cytochrome c oxidase assembly factor -1.66581
DPYSL2 dihydropyrimidinase-like 2 -1.66503
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 -1.66485
NGFR nerve growth factor receptor -1.66478
SDC3 syndecan 3 -1.66476
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -1.66376
CFDP1 craniofacial development protein 1 -1.66321
RFC5 replication factor C (activator 1) 5, 36.5kDa -1.66114
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -1.66034
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -1.65948
TEX261 testis expressed 261 -1.65708
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -1.65626
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -1.65568
ZNF160 zinc finger protein 160 -1.65107
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -1.6504
RAB31 RAB31, member RAS oncogene family -1.64939
ZNF137P zinc finger protein 137, pseudogene -1.64704
ELF4 E74-like factor 4 (ets domain transcription factor) -1.64462
UBE2B ubiquitin-conjugating enzyme E2B -1.64337
RBM3 RNA binding motif (RNP1, RRM) protein 3 -1.64247
EED embryonic ectoderm development -1.64071
HPRT1 hypoxanthine phosphoribosyltransferase 1 -1.64034
SERBP1 SERPINE1 mRNA binding protein 1 -1.6384
EIF3A eukaryotic translation initiation factor 3, subunit A -1.63701
ARRB2 arrestin, beta 2 -1.6365
CLPTM1 cleft lip and palate associated transmembrane protein 1 -1.6342
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -1.63292
SMAD2 SMAD family member 2 -1.63245
WBP4 WW domain binding protein 4 -1.63084
GRB2 growth factor receptor-bound protein 2 -1.6307
RPS3A ribosomal protein S3A -1.62723
MED13 mediator complex subunit 13 -1.62104
JUP junction plakoglobin -1.60947
HAGH hydroxyacylglutathione hydrolase -1.60914
EEF2 eukaryotic translation elongation factor 2 -1.6077
YBX1 Y box binding protein 1 -1.60328
NCAN neurocan -1.59894
NCR3 natural cytotoxicity triggering receptor 3 -1.5973
DNPEP aspartyl aminopeptidase -1.59483
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -1.59481
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -1.59315
BBIP1 BBSome interacting protein 1 -1.58955
AHNAK AHNAK nucleoprotein -1.58847
AP1B1 adaptor-related protein complex 1, beta 1 subunit -1.58726
PTOV1 prostate tumor overexpressed 1 -1.5838
NFYB nuclear transcription factor Y, beta -1.58221
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -1.58215
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -1.58161
CLTB clathrin, light chain B -1.57878
NISCH nischarin -1.57827
SMC5 structural maintenance of chromosomes 5 -1.57791
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -1.5736
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -1.56681
NCL nucleolin -1.56424
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -1.56383
KAT2B K(lysine) acetyltransferase 2B -1.56326
TTF2 transcription termination factor, RNA polymerase II -1.55902
INTS10 integrator complex subunit 10 -1.55901
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -1.55641
AFG3L2 AFG3-like AAA ATPase 2 -1.55298
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -1.55016
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -1.54992
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding) -1.54797
ERCC1 excision repair cross-complementation group 1 -1.54567
HTATSF1 HIV-1 Tat specific factor 1 -1.5452
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -1.54447
URI1 URI1, prefoldin-like chaperone -1.54361
PTBP1 polypyrimidine tract binding protein 1 -1.54222
SFSWAP splicing factor, suppressor of white-apricot family -1.54147
FAM214B family with sequence similarity 214, member B -1.53816
GCDH glutaryl-CoA dehydrogenase -1.53719
IL9R interleukin 9 receptor -1.53712
YARS tyrosyl-tRNA synthetase -1.53709
TLK2 tousled-like kinase 2 -1.53691
EIF3K eukaryotic translation initiation factor 3, subunit K -1.5324
CLK1 CDC-like kinase 1 -1.52937
KIAA0586 KIAA0586 -1.52892
KAT7 K(lysine) acetyltransferase 7 -1.52605
NAGA N-acetylgalactosaminidase, alpha- -1.52597
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -1.52415
IRS2 insulin receptor substrate 2 -1.52177
ZNF189 zinc finger protein 189 -1.51918
SRSF1 serine/arginine-rich splicing factor 1 -1.51878
PTOV1-AS1 PTOV1 antisense RNA 1 -1.51777
C6ORF106 chromosome 6 open reading frame 106 -1.51762
ARPP19 cAMP-regulated phosphoprotein, 19kDa -1.5151
DGAT1 diacylglycerol O-acyltransferase 1 -1.50871
FAM50B family with sequence similarity 50, member B -1.50813
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -1.50708
CD33 CD33 molecule -1.50367
SMNDC1 survival motor neuron domain containing 1 -1.5024
STAG2 stromal antigen 2 -1.49828
SPAG1 sperm associated antigen 1 -1.49594