Fatty acid, triacylglycerol, and ketone body metabolism Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-535734
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Genes

181 proteins participating in the Fatty acid, triacylglycerol, and ketone body metabolism pathway from the Reactome Pathways dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACADL acyl-CoA dehydrogenase, long chain
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADVL acyl-CoA dehydrogenase, very long chain
ACAT1 acetyl-CoA acetyltransferase 1
ACLY ATP citrate lyase
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACSL5 acyl-CoA synthetase long-chain family member 5
ACSL6 acyl-CoA synthetase long-chain family member 6
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALAS1 5'-aminolevulinate synthase 1
ANGPTL4 angiopoietin-like 4
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CARM1 coactivator-associated arginine methyltransferase 1
CCNC cyclin C
CD36 CD36 molecule (thrombospondin receptor)
CDK19 cyclin-dependent kinase 19
CDK8 cyclin-dependent kinase 8
CHD9 chromodomain helicase DNA binding protein 9
CLOCK clock circadian regulator
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT1B carnitine palmitoyltransferase 1B (muscle)
CPT2 carnitine palmitoyltransferase 2
CREBBP CREB binding protein
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DGAT1 diacylglycerol O-acyltransferase 1
DGAT2 diacylglycerol O-acyltransferase 2
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
ECI1 enoyl-CoA delta isomerase 1
ELOVL1 ELOVL fatty acid elongase 1
ELOVL2 ELOVL fatty acid elongase 2
ELOVL3 ELOVL fatty acid elongase 3
ELOVL4 ELOVL fatty acid elongase 4
ELOVL5 ELOVL fatty acid elongase 5
ELOVL6 ELOVL fatty acid elongase 6
ELOVL7 ELOVL fatty acid elongase 7
EP300 E1A binding protein p300
ESRRA estrogen-related receptor alpha
FABP1 fatty acid binding protein 1, liver
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FHL2 four and a half LIM domains 2
G0S2 G0/G1 switch 2
GK glycerol kinase
GK2 glycerol kinase 2
GK3P glycerol kinase 3 pseudogene
GLIPR1 GLI pathogenesis-related 1
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GRHL1 grainyhead-like 1 (Drosophila)
HADH hydroxyacyl-CoA dehydrogenase
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HDAC3 histone deacetylase 3
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
LCLAT1 lysocardiolipin acyltransferase 1
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
LPIN1 lipin 1
LPIN2 lipin 2
LPIN3 lipin 3
MCEE methylmalonyl CoA epimerase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED1 mediator complex subunit 1
MED10 mediator complex subunit 10
MED11 mediator complex subunit 11
MED12 mediator complex subunit 12
MED13 mediator complex subunit 13
MED13L mediator complex subunit 13-like
MED14 mediator complex subunit 14
MED15 mediator complex subunit 15
MED16 mediator complex subunit 16
MED17 mediator complex subunit 17
MED18 mediator complex subunit 18
MED19 mediator complex subunit 19
MED20 mediator complex subunit 20
MED21 mediator complex subunit 21
MED22 mediator complex subunit 22
MED23 mediator complex subunit 23
MED24 mediator complex subunit 24
MED25 mediator complex subunit 25
MED26 mediator complex subunit 26
MED27 mediator complex subunit 27
MED29 mediator complex subunit 29
MED30 mediator complex subunit 30
MED31 mediator complex subunit 31
MED4 mediator complex subunit 4
MED6 mediator complex subunit 6
MED7 mediator complex subunit 7
MED8 mediator complex subunit 8
MED9 mediator complex subunit 9
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MUT methylmalonyl CoA mutase
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NCOA6 nuclear receptor coactivator 6
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFYA nuclear transcription factor Y, alpha
NFYB nuclear transcription factor Y, beta
NFYC nuclear transcription factor Y, gamma
NPAS2 neuronal PAS domain protein 2
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRF1 nuclear respiratory factor 1
OXCT1 3-oxoacid CoA transferase 1
PCCA propionyl CoA carboxylase, alpha polypeptide
PCCB propionyl CoA carboxylase, beta polypeptide
PEX11A peroxisomal biogenesis factor 11 alpha
PLIN2 perilipin 2
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RORA RAR-related orphan receptor A
RXRA retinoid X receptor, alpha
SIN3A SIN3 transcription regulator family member A
SIN3B SIN3 transcription regulator family member B
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SP1 Sp1 transcription factor
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 TEA domain family member 2
TEAD3 TEA domain family member 3
TEAD4 TEA domain family member 4
TECR trans-2,3-enoyl-CoA reductase
TECRL trans-2,3-enoyl-CoA reductase-like
TGS1 trimethylguanosine synthase 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIB3 tribbles pseudokinase 3
TXNRD1 thioredoxin reductase 1
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
WWTR1 WW domain containing transcription regulator 1
YAP1 Yes-associated protein 1