Familial combined hyperlipidaemia_Blood monocyte_GSE11393 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE11393
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Genes

600 genes differentially expressed during Familial combined hyperlipidaemia_Blood monocyte_GSE11393 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
PANK3 pantothenate kinase 3 3.69227
CMA1 chymase 1, mast cell 3.33207
HAX1 HCLS1 associated protein X-1 3.15871
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 3.12864
GLO1 glyoxalase I 3.11102
MOG myelin oligodendrocyte glycoprotein 3.0766
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.06377
FAM155A family with sequence similarity 155, member A 2.97572
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 2.93698
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 2.93116
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.89209
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 2.81526
SNF8 SNF8, ESCRT-II complex subunit 2.80468
CALB1 calbindin 1, 28kDa 2.78902
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 2.77507
FDFT1 farnesyl-diphosphate farnesyltransferase 1 2.72748
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 2.68019
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 2.66277
SAGE1 sarcoma antigen 1 2.64526
COX7BP1 cytochrome c oxidase subunit VIIb pseudogene 1 2.61551
PSD3 pleckstrin and Sec7 domain containing 3 2.58071
GPX1 glutathione peroxidase 1 2.50662
LPCAT3 lysophosphatidylcholine acyltransferase 3 2.50515
ZNF157 zinc finger protein 157 2.4676
PKP4 plakophilin 4 2.46107
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 2.45699
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 2.42812
CARM1 coactivator-associated arginine methyltransferase 1 2.40907
ZMIZ2 zinc finger, MIZ-type containing 2 2.39752
FAM20B family with sequence similarity 20, member B 2.39257
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2.38636
OBSL1 obscurin-like 1 2.3832
CLCN6 chloride channel, voltage-sensitive 6 2.36024
CLTA clathrin, light chain A 2.35732
LSM12 LSM12 homolog (S. cerevisiae) 2.35576
TMSB4Y thymosin beta 4, Y-linked 2.34326
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.30755
RHOT2 ras homolog family member T2 2.2732
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 2.26992
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 2.26614
LCAT lecithin-cholesterol acyltransferase 2.25813
AJAP1 adherens junctions associated protein 1 2.24791
TPST2 tyrosylprotein sulfotransferase 2 2.24602
GRWD1 glutamate-rich WD repeat containing 1 2.23994
MZF1 myeloid zinc finger 1 2.23977
ASMT acetylserotonin O-methyltransferase 2.20082
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 2.19318
TMEM131 transmembrane protein 131 2.18599
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.18401
PLN phospholamban 2.16276
COG4 component of oligomeric golgi complex 4 2.13881
PTGES2 prostaglandin E synthase 2 2.13812
FGF7 fibroblast growth factor 7 2.13082
ZFYVE9 zinc finger, FYVE domain containing 9 2.12648
PLSCR2 phospholipid scramblase 2 2.10882
ZNF580 zinc finger protein 580 2.10649
TPO thyroid peroxidase 2.1034
MGAT4C MGAT4 family, member C 2.10304
PCDH8 protocadherin 8 2.0892
HGFAC HGF activator 2.0847
STK3 serine/threonine kinase 3 2.07829
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.07656
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 2.06671
IFT52 intraflagellar transport 52 2.06064
ADRBK2 adrenergic, beta, receptor kinase 2 2.05887
MYO1B myosin IB 2.03954
ARHGAP11A Rho GTPase activating protein 11A 2.03101
DPT dermatopontin 2.01514
CRHR1 corticotropin releasing hormone receptor 1 2.01034
CLCN2 chloride channel, voltage-sensitive 2 2.00399
MID1 midline 1 1.99268
GMEB2 glucocorticoid modulatory element binding protein 2 1.97894
PKD1 polycystic kidney disease 1 (autosomal dominant) 1.97407
MED15 mediator complex subunit 15 1.97025
ENY2 enhancer of yellow 2 homolog (Drosophila) 1.96395
OGG1 8-oxoguanine DNA glycosylase 1.95135
MEF2A myocyte enhancer factor 2A 1.94017
FKRP fukutin related protein 1.93805
HIST1H4L histone cluster 1, H4l 1.93529
DCTN2 dynactin 2 (p50) 1.93476
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.93087
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 1.90949
GLS2 glutaminase 2 (liver, mitochondrial) 1.87831
ZNF473 zinc finger protein 473 1.87815
GTF2A2 general transcription factor IIA, 2, 12kDa 1.87715
PKP1 plakophilin 1 1.87633
ZCCHC14 zinc finger, CCHC domain containing 14 1.87444
DGUOK deoxyguanosine kinase 1.87165
RANBP1 RAN binding protein 1 1.87057
WIZ widely interspaced zinc finger motifs 1.86788
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 1.85388
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 1.84148
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.84086
TUG1 taurine up-regulated 1 (non-protein coding) 1.83379
ATRNL1 attractin-like 1 1.83015
RBP1 retinol binding protein 1, cellular 1.82598
PNMA2 paraneoplastic Ma antigen 2 1.82546
MRPL2 mitochondrial ribosomal protein L2 1.82243
CREBZF CREB/ATF bZIP transcription factor 1.8181
TIPIN TIMELESS interacting protein 1.81643
EMC1 ER membrane protein complex subunit 1 1.81379
FGB fibrinogen beta chain 1.80832
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.80314
BCL2L2 BCL2-like 2 1.80124
EPB41L2 erythrocyte membrane protein band 4.1-like 2 1.79961
BUD31 BUD31 homolog (S. cerevisiae) 1.79943
CNPPD1 cyclin Pas1/PHO80 domain containing 1 1.79438
ZNF672 zinc finger protein 672 1.78836
C19ORF73 chromosome 19 open reading frame 73 1.78629
ZNF142 zinc finger protein 142 1.7818
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 1.77901
TEX261 testis expressed 261 1.77569
ANGPTL2 angiopoietin-like 2 1.77239
SCGB2A1 secretoglobin, family 2A, member 1 1.76855
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.76517
BCL9 B-cell CLL/lymphoma 9 1.76393
DESI2 desumoylating isopeptidase 2 1.7601
MYO7B myosin VIIB 1.75966
IQCK IQ motif containing K 1.75688
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.75635
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 1.7538
VN1R1 vomeronasal 1 receptor 1 1.75171
DZIP3 DAZ interacting zinc finger protein 3 1.75077
TNP1 transition protein 1 (during histone to protamine replacement) 1.7499
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.74415
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.74087
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.73919
ZNF133 zinc finger protein 133 1.73827
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1.73416
PAWR PRKC, apoptosis, WT1, regulator 1.73376
HACD1 3-hydroxyacyl-CoA dehydratase 1 1.73336
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.73096
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1.72644
SEPT7 septin 7 1.72302
AHCYL1 adenosylhomocysteinase-like 1 1.71931
TTLL5 tubulin tyrosine ligase-like family member 5 1.71927
TJP1 tight junction protein 1 1.71865
UBE3A ubiquitin protein ligase E3A 1.71513
USP22 ubiquitin specific peptidase 22 1.71229
MIS18A MIS18 kinetochore protein A 1.70818
UBOX5 U-box domain containing 5 1.70469
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.70421
RPL39L ribosomal protein L39-like 1.70371
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 1.70146
GJB5 gap junction protein, beta 5, 31.1kDa 1.70062
RPS27L ribosomal protein S27-like 1.6973
RAB1B RAB1B, member RAS oncogene family 1.69678
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.69501
CPNE6 copine VI (neuronal) 1.68637
CCDC71 coiled-coil domain containing 71 1.68636
MTCH2 mitochondrial carrier 2 1.68503
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.68357
UBE2A ubiquitin-conjugating enzyme E2A 1.67752
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.66978
ETHE1 ethylmalonic encephalopathy 1 1.66974
BMP2 bone morphogenetic protein 2 1.66891
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 1.66606
C6ORF223 chromosome 6 open reading frame 223 1.65224
ALDOA aldolase A, fructose-bisphosphate 1.64855
FBXL15 F-box and leucine-rich repeat protein 15 1.64338
ZER1 zyg-11 related, cell cycle regulator 1.64285
HEMK1 HemK methyltransferase family member 1 1.63985
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.63789
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 1.63569
LYPLA2 lysophospholipase II 1.63553
NCAPD2 non-SMC condensin I complex, subunit D2 1.6346
ATXN7L1 ataxin 7-like 1 1.63446
GPBP1L1 GC-rich promoter binding protein 1-like 1 1.63438
SHCBP1 SHC SH2-domain binding protein 1 1.63237
LAGE3 L antigen family, member 3 1.63135
MAN1A2 mannosidase, alpha, class 1A, member 2 1.63134
SCGB1D2 secretoglobin, family 1D, member 2 1.62744
RUFY3 RUN and FYVE domain containing 3 1.62297
CD40 CD40 molecule, TNF receptor superfamily member 5 1.62124
TST thiosulfate sulfurtransferase (rhodanese) 1.6194
CDC27 cell division cycle 27 1.6182
TADA2A transcriptional adaptor 2A 1.61548
GCM2 glial cells missing homolog 2 (Drosophila) 1.61197
CDC34 cell division cycle 34 1.61194
GRM8 glutamate receptor, metabotropic 8 1.60814
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 1.60694
APOF apolipoprotein F 1.60516
LOR loricrin 1.59438
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 1.59376
MFSD1 major facilitator superfamily domain containing 1 1.59083
TACC2 transforming, acidic coiled-coil containing protein 2 1.58407
ARSJ arylsulfatase family, member J 1.58303
AUP1 ancient ubiquitous protein 1 1.57772
DSG1 desmoglein 1 1.57685
CRYGA crystallin, gamma A 1.57685
TRPM1 transient receptor potential cation channel, subfamily M, member 1 1.57581
IFNA6 interferon, alpha 6 1.57251
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 1.57138
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.56411
GSTO1 glutathione S-transferase omega 1 1.56344
MED31 mediator complex subunit 31 1.56272
TLL1 tolloid-like 1 1.56151
TJAP1 tight junction associated protein 1 (peripheral) 1.5606
ANKMY1 ankyrin repeat and MYND domain containing 1 1.55801
HAUS7 HAUS augmin-like complex, subunit 7 1.556
TMX4 thioredoxin-related transmembrane protein 4 1.55575
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 1.55477
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 1.5538
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding) 1.55141
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.54879
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 1.54282
AAMDC adipogenesis associated, Mth938 domain containing 1.5401
POFUT2 protein O-fucosyltransferase 2 1.5361
FBXL18 F-box and leucine-rich repeat protein 18 1.53493
COL3A1 collagen, type III, alpha 1 1.53463
USP29 ubiquitin specific peptidase 29 1.5337
TMPRSS11E transmembrane protease, serine 11E 1.53126
DEFB1 defensin, beta 1 1.53018
TRAPPC3 trafficking protein particle complex 3 1.52931
SH2B1 SH2B adaptor protein 1 1.52753
SRR serine racemase 1.52705
C19ORF60 chromosome 19 open reading frame 60 1.52695
STOML2 stomatin (EPB72)-like 2 1.52623
RAB27B RAB27B, member RAS oncogene family 1.52384
VEGFB vascular endothelial growth factor B 1.52293
SNX19 sorting nexin 19 1.52097
ZFYVE26 zinc finger, FYVE domain containing 26 1.51793
RBM42 RNA binding motif protein 42 1.51545
CAND1 cullin-associated and neddylation-dissociated 1 1.5103
EFCAB1 EF-hand calcium binding domain 1 1.50962
ZNF204P zinc finger protein 204, pseudogene 1.50819
TRIM48 tripartite motif containing 48 1.50774
SCN2A sodium channel, voltage gated, type II alpha subunit 1.49828
TEX30 testis expressed 30 1.49756
TBCE tubulin folding cofactor E 1.49661
RGS10 regulator of G-protein signaling 10 1.49539
TXNL1 thioredoxin-like 1 1.49403
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 1.49402
C5ORF15 chromosome 5 open reading frame 15 1.49287
AVPR1A arginine vasopressin receptor 1A 1.48768
ZNF695 zinc finger protein 695 1.48743
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.48573
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.48305
RAD23A RAD23 homolog A (S. cerevisiae) 1.48205
CDYL chromodomain protein, Y-like 1.4818
GPR27 G protein-coupled receptor 27 1.47933
PBK PDZ binding kinase 1.4764
ANK2 ankyrin 2, neuronal 1.47597
MAP2K2 mitogen-activated protein kinase kinase 2 1.47473
PANK4 pantothenate kinase 4 1.47385
POU6F1 POU class 6 homeobox 1 1.47283
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.4692
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.46778
CSN3 casein kappa 1.46767
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.4661
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 1.46404
KCTD2 potassium channel tetramerization domain containing 2 1.46365
VENTX VENT homeobox 1.46
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 1.45648
PITX1 paired-like homeodomain 1 1.45527
PCDHGC3 protocadherin gamma subfamily C, 3 1.45349
CTSF cathepsin F 1.44947
TNC tenascin C 1.44904
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 1.44376
PMCH pro-melanin-concentrating hormone 1.44333
GFER growth factor, augmenter of liver regeneration 1.44234
CDK9 cyclin-dependent kinase 9 1.44168
NCLN nicalin 1.4411
EDNRA endothelin receptor type A 1.44081
GPAA1 glycosylphosphatidylinositol anchor attachment 1 1.43873
RBMX RNA binding motif protein, X-linked 1.43293
SFT2D2 SFT2 domain containing 2 1.4279
MRPL12 mitochondrial ribosomal protein L12 1.4222
GDF11 growth differentiation factor 11 1.42201
C22ORF29 chromosome 22 open reading frame 29 1.42106
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.42104
TMCO1 transmembrane and coiled-coil domains 1 1.42079
PALM paralemmin 1.42
ASB4 ankyrin repeat and SOCS box containing 4 1.4167
SLC22A24 solute carrier family 22, member 24 1.41611
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 1.41582
CA3 carbonic anhydrase III 1.41565
SCRG1 stimulator of chondrogenesis 1 1.41478
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 1.41366
ZNF544 zinc finger protein 544 1.41307
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 1.41274
CPA1 carboxypeptidase A1 (pancreatic) 1.41217
KIAA0586 KIAA0586 1.40906
C8G complement component 8, gamma polypeptide 1.40866
POLL polymerase (DNA directed), lambda 1.40718
USF2 upstream transcription factor 2, c-fos interacting 1.40642
TGM4 transglutaminase 4 1.40641
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 1.40607
FGFR3 fibroblast growth factor receptor 3 1.40321
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.40019
HSF1 heat shock transcription factor 1 1.39885
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 1.39493
BMP10 bone morphogenetic protein 10 1.39448
EIF6 eukaryotic translation initiation factor 6 1.39409
SERF2 small EDRK-rich factor 2 1.39373
INTS5 integrator complex subunit 5 1.39324
MTCH1 mitochondrial carrier 1 1.39278
FAF2 Fas associated factor family member 2 1.3922
SDF2 stromal cell-derived factor 2 1.39105
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 1.38626

decreased expression

Symbol Name Standardized Value
TSHR thyroid stimulating hormone receptor -4.02063
LOC57399 uncharacterized gastric protein ZA52P -3.71271
TARDBPP1 TAR DNA binding protein pseudogene 1 -3.60701
RORB RAR-related orphan receptor B -3.37625
LEP leptin -3.20036
CPE carboxypeptidase E -3.17964
TMPRSS2 transmembrane protease, serine 2 -3.122
PXDC1 PX domain containing 1 -3.00407
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -2.84139
NOX3 NADPH oxidase 3 -2.82042
RAI2 retinoic acid induced 2 -2.74024
SLIT3 slit homolog 3 (Drosophila) -2.68818
FRMPD1 FERM and PDZ domain containing 1 -2.67093
HOXD1 homeobox D1 -2.65854
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.63332
SCIN scinderin -2.60961
RBPMS RNA binding protein with multiple splicing -2.60234
FRMD4B FERM domain containing 4B -2.57272
NUBPL nucleotide binding protein-like -2.54362
PPL periplakin -2.54234
PLCB4 phospholipase C, beta 4 -2.53758
ANP32A-IT1 ANP32A intronic transcript 1 -2.48433
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -2.46649
HIST1H3G histone cluster 1, H3g -2.429
PXN paxillin -2.42362
RHAG Rh-associated glycoprotein -2.41042
SFXN1 sideroflexin 1 -2.37489
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -2.355
USP2 ubiquitin specific peptidase 2 -2.28014
DSCC1 DNA replication and sister chromatid cohesion 1 -2.27671
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -2.27581
UST uronyl-2-sulfotransferase -2.26501
STK17B serine/threonine kinase 17b -2.26037
ESR2 estrogen receptor 2 (ER beta) -2.25374
LOC729164 hCG1732469 -2.24047
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 -2.22778
RAB36 RAB36, member RAS oncogene family -2.20656
SFTPB surfactant protein B -2.20651
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -2.20519
TMOD2 tropomodulin 2 (neuronal) -2.17933
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 -2.17354
HIST1H2AM histone cluster 1, H2am -2.17108
SYNC syncoilin, intermediate filament protein -2.14938
SOGA1 suppressor of glucose, autophagy associated 1 -2.14069
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.13235
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -2.12926
SMAD9 SMAD family member 9 -2.12923
UBE2B ubiquitin-conjugating enzyme E2B -2.12229
MUTYH mutY homolog -2.12023
TP53I13 tumor protein p53 inducible protein 13 -2.11161
BTNL3 butyrophilin-like 3 -2.10918
LGI1 leucine-rich, glioma inactivated 1 -2.10273
OR2B2 olfactory receptor, family 2, subfamily B, member 2 -2.09784
ZNF334 zinc finger protein 334 -2.08891
CDHR5 cadherin-related family member 5 -2.05254
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 -2.04223
EPHB3 EPH receptor B3 -2.04177
SERINC3 serine incorporator 3 -2.03625
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -2.03098
SCNN1G sodium channel, non voltage gated 1 gamma subunit -2.01832
RPS15A ribosomal protein S15a -2.00285
STRA13 stimulated by retinoic acid 13 -2.00027
PTGIS prostaglandin I2 (prostacyclin) synthase -1.99843
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -1.99485
MYF6 myogenic factor 6 (herculin) -1.9932
NECAB2 N-terminal EF-hand calcium binding protein 2 -1.98965
CRP C-reactive protein, pentraxin-related -1.98081
HIST1H1D histone cluster 1, H1d -1.97648
ATP10A ATPase, class V, type 10A -1.97602
SPN sialophorin -1.96624
NUP98 nucleoporin 98kDa -1.96608
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -1.93915
YTHDC1 YTH domain containing 1 -1.93873
SSX4 synovial sarcoma, X breakpoint 4 -1.93589
CCNE2 cyclin E2 -1.9338
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) -1.93036
NEU3 sialidase 3 (membrane sialidase) -1.91905
POLR1B polymerase (RNA) I polypeptide B, 128kDa -1.91119
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -1.90141
CLDN1 claudin 1 -1.90123
UNC93A unc-93 homolog A (C. elegans) -1.89626
COL8A1 collagen, type VIII, alpha 1 -1.89157
WASL Wiskott-Aldrich syndrome-like -1.88941
ARF1P1 ADP-ribosylation factor 1 pseudogene 1 -1.88837
CNN2 calponin 2 -1.88291
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -1.87327
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene -1.87255
QSER1 glutamine and serine rich 1 -1.86686
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -1.86167
LPP LIM domain containing preferred translocation partner in lipoma -1.85767
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -1.85003
SPAG11B sperm associated antigen 11B -1.8498
TNRC6C trinucleotide repeat containing 6C -1.84837
SOD3 superoxide dismutase 3, extracellular -1.83749
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 -1.83302
GLI2 GLI family zinc finger 2 -1.81791
WWTR1 WW domain containing transcription regulator 1 -1.80712
AAK1 AP2 associated kinase 1 -1.80601
MYOZ2 myozenin 2 -1.80557
TUBGCP2 tubulin, gamma complex associated protein 2 -1.80444
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -1.79739
HCRTR1 hypocretin (orexin) receptor 1 -1.78043
PODNL1 podocan-like 1 -1.77912
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase -1.77865
RIMBP2 RIMS binding protein 2 -1.76269
ACTB actin, beta -1.75516
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -1.7533
PGBD5 piggyBac transposable element derived 5 -1.74123
KIAA0319 KIAA0319 -1.73484
NYNRIN NYN domain and retroviral integrase containing -1.73388
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -1.72658
SLMO1 slowmo homolog 1 (Drosophila) -1.72344
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -1.71773
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -1.71469
RRBP1 ribosome binding protein 1 -1.70997
UPK1B uroplakin 1B -1.70148
RAP2A RAP2A, member of RAS oncogene family -1.697
PEG3 paternally expressed 3 -1.68619
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -1.68031
RIMS2 regulating synaptic membrane exocytosis 2 -1.67974
XPO6 exportin 6 -1.66553
MMP20 matrix metallopeptidase 20 -1.66021
PLS3 plastin 3 -1.65807
CASZ1 castor zinc finger 1 -1.65458
GMFG glia maturation factor, gamma -1.65362
FBXO46 F-box protein 46 -1.65221
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 -1.6467
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -1.64654
ZBTB8B zinc finger and BTB domain containing 8B -1.64579
COPG2 coatomer protein complex, subunit gamma 2 -1.64068
NAT6 N-acetyltransferase 6 (GCN5-related) -1.64017
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -1.6401
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -1.62999
MST1 macrophage stimulating 1 -1.62875
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 -1.62736
LMTK2 lemur tyrosine kinase 2 -1.62004
LIG4 ligase IV, DNA, ATP-dependent -1.61763
LRP2 low density lipoprotein receptor-related protein 2 -1.61692
HHLA1 HERV-H LTR-associating 1 -1.61509
ARID4B AT rich interactive domain 4B (RBP1-like) -1.59864
C19ORF57 chromosome 19 open reading frame 57 -1.59846
NCR1 natural cytotoxicity triggering receptor 1 -1.59645
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) -1.5924
RNF17 ring finger protein 17 -1.58761
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -1.58168
AP1M2 adaptor-related protein complex 1, mu 2 subunit -1.57876
BMP8A bone morphogenetic protein 8a -1.57813
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -1.57274
EML1 echinoderm microtubule associated protein like 1 -1.57258
WISP1 WNT1 inducible signaling pathway protein 1 -1.57128
ANKRD6 ankyrin repeat domain 6 -1.57048
COL4A1 collagen, type IV, alpha 1 -1.56987
GRIA3 glutamate receptor, ionotropic, AMPA 3 -1.5655
AIM1L absent in melanoma 1-like -1.56022
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 -1.55963
DMP1 dentin matrix acidic phosphoprotein 1 -1.55475
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 -1.55085
GP2 glycoprotein 2 (zymogen granule membrane) -1.54611
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -1.54448
PDE4C phosphodiesterase 4C, cAMP-specific -1.54212
STXBP3 syntaxin binding protein 3 -1.53876
DST dystonin -1.53821
TPT1 tumor protein, translationally-controlled 1 -1.53574
HRH2 histamine receptor H2 -1.53442
DIDO1 death inducer-obliterator 1 -1.52538
NPR2 natriuretic peptide receptor 2 -1.5196
UPK1A uroplakin 1A -1.5191
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -1.5176
SLC16A4 solute carrier family 16, member 4 -1.5017
INSL5 insulin-like 5 -1.50113
LAMA4 laminin, alpha 4 -1.50036
ARRB1 arrestin, beta 1 -1.49953
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.49875
POM121 POM121 transmembrane nucleoporin -1.48896
CAV2 caveolin 2 -1.48534
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -1.48434
PYY peptide YY -1.48341
IVD isovaleryl-CoA dehydrogenase -1.48147
MBNL1 muscleblind-like splicing regulator 1 -1.48097
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -1.4758
SNTA1 syntrophin, alpha 1 -1.47175
ADRB3 adrenoceptor beta 3 -1.46991
USP10 ubiquitin specific peptidase 10 -1.46792
AGTR1 angiotensin II receptor, type 1 -1.46545
PAX3 paired box 3 -1.45879
RANBP2 RAN binding protein 2 -1.45655
PTPN20 protein tyrosine phosphatase, non-receptor type 20 -1.45112
VIP vasoactive intestinal peptide -1.44881
LOC100130741 uncharacterized LOC100130741 -1.44352
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1 -1.44209
PCDHB6 protocadherin beta 6 -1.43288
RBBP5 retinoblastoma binding protein 5 -1.43277
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -1.43115
MUC16 mucin 16, cell surface associated -1.42946
HLA-A major histocompatibility complex, class I, A -1.42303
LOC100131532 uncharacterized LOC100131532 -1.42233
IFNA16 interferon, alpha 16 -1.42053
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -1.41998
GPR87 G protein-coupled receptor 87 -1.41207
PGK1 phosphoglycerate kinase 1 -1.4119
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 -1.41145
MLF1 myeloid leukemia factor 1 -1.41123
IL5RA interleukin 5 receptor, alpha -1.4109
MOCS1 molybdenum cofactor synthesis 1 -1.41035
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -1.40994
DENND2A DENN/MADD domain containing 2A -1.40954
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -1.40532
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase -1.40487
FOXI1 forkhead box I1 -1.40211
HLA-C major histocompatibility complex, class I, C -1.40042
DOLPP1 dolichyldiphosphatase 1 -1.40024
CASP3 caspase 3, apoptosis-related cysteine peptidase -1.39634
SRGN serglycin -1.39575
RNPEP arginyl aminopeptidase (aminopeptidase B) -1.39535
CPN1 carboxypeptidase N, polypeptide 1 -1.39456
ZNF460 zinc finger protein 460 -1.39031
FOXD1 forkhead box D1 -1.38389
SOX9 SRY (sex determining region Y)-box 9 -1.38187
SYNPO2L synaptopodin 2-like -1.37911
EIF4H eukaryotic translation initiation factor 4H -1.37715
RPL39 ribosomal protein L39 -1.37707
ST7L suppression of tumorigenicity 7 like -1.37522
RAB27A RAB27A, member RAS oncogene family -1.37494
BAZ1A bromodomain adjacent to zinc finger domain, 1A -1.37409
ANGPTL3 angiopoietin-like 3 -1.37396
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -1.37257
OMD osteomodulin -1.3698
MCAM melanoma cell adhesion molecule -1.36953
SPC25 SPC25, NDC80 kinetochore complex component -1.36889
CLEC4M C-type lectin domain family 4, member M -1.36692
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -1.36504
RHOF ras homolog family member F (in filopodia) -1.36491
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 -1.36438
DBT dihydrolipoamide branched chain transacylase E2 -1.36392
TSGA10 testis specific, 10 -1.36329
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -1.36243
CASC1 cancer susceptibility candidate 1 -1.36048
AGER advanced glycosylation end product-specific receptor -1.35674
TMC7 transmembrane channel-like 7 -1.35601
CLCA4 chloride channel accessory 4 -1.34947
CCKAR cholecystokinin A receptor -1.3494
FAM186A family with sequence similarity 186, member A -1.34718
PIWIL2 piwi-like RNA-mediated gene silencing 2 -1.34624
KIF1A kinesin family member 1A -1.34398
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) -1.34038
GPR12 G protein-coupled receptor 12 -1.33882
TAGLN3 transgelin 3 -1.3387
KCNK12 potassium channel, two pore domain subfamily K, member 12 -1.33819
TINAGL1 tubulointerstitial nephritis antigen-like 1 -1.33721
ITM2B integral membrane protein 2B -1.3345
OR12D3 olfactory receptor, family 12, subfamily D, member 3 -1.32447
OGDHL oxoglutarate dehydrogenase-like -1.32355
GFRA2 GDNF family receptor alpha 2 -1.32262
BIRC2 baculoviral IAP repeat containing 2 -1.32103
DEFB4A defensin, beta 4A -1.31471
PTPRD protein tyrosine phosphatase, receptor type, D -1.31304
RPS24 ribosomal protein S24 -1.3128
GLRA3 glycine receptor, alpha 3 -1.30829
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein -1.30517
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -1.30401
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -1.3035
MED14 mediator complex subunit 14 -1.30248
SV2C synaptic vesicle glycoprotein 2C -1.30016
SUB1 SUB1 homolog (S. cerevisiae) -1.29749
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -1.29691
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -1.29684
RPS23 ribosomal protein S23 -1.29581
KL klotho -1.29549
RPS27 ribosomal protein S27 -1.29483
FOXA2 forkhead box A2 -1.29238
HCG4B HLA complex group 4B (non-protein coding) -1.2918
PRDM11 PR domain containing 11 -1.29068
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -1.28876
AFM afamin -1.28765
SLC38A4 solute carrier family 38, member 4 -1.28699
SLC25A30 solute carrier family 25, member 30 -1.28593
PRNP prion protein -1.28557
DHRS11 dehydrogenase/reductase (SDR family) member 11 -1.2849
EFCAB11 EF-hand calcium binding domain 11 -1.28436
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -1.28212
SEPT11 septin 11 -1.28171
LRTM2 leucine-rich repeats and transmembrane domains 2 -1.28129
KIAA0040 KIAA0040 -1.28041
USP49 ubiquitin specific peptidase 49 -1.27934
ADNP activity-dependent neuroprotector homeobox -1.27874
SP3 Sp3 transcription factor -1.27848
VGLL1 vestigial-like family member 1 -1.27509
RYR2 ryanodine receptor 2 (cardiac) -1.27435
ERN2 endoplasmic reticulum to nucleus signaling 2 -1.27375
GH2 growth hormone 2 -1.27167
ZFAND6 zinc finger, AN1-type domain 6 -1.27099
POLQ polymerase (DNA directed), theta -1.2706
RNF144A ring finger protein 144A -1.26616
KCTD14 potassium channel tetramerization domain containing 14 -1.26368
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -1.26082
FZD4 frizzled class receptor 4 -1.26013
KRT34 keratin 34, type I -1.25978
FBXL2 F-box and leucine-rich repeat protein 2 -1.25945
RPL6P17 ribosomal protein L6 pseudogene 17 -1.2591
PDZK1 PDZ domain containing 1 -1.25823