EGFR_druginhibition_83_GSE27640 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27640
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Genes

600 genes differentially expressed following the EGFR_druginhibition_83_GSE27640 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 3.55455
PHACTR1 phosphatase and actin regulator 1 3.43238
PTPRS protein tyrosine phosphatase, receptor type, S 3.36067
UPK1A uroplakin 1A 3.30978
SLFN13 schlafen family member 13 3.25283
DSCAM Down syndrome cell adhesion molecule 2.96141
RECQL RecQ helicase-like 2.92482
FASTKD1 FAST kinase domains 1 2.86968
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 2.75181
NFS1 NFS1 cysteine desulfurase 2.72887
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 2.72177
ZBTB22 zinc finger and BTB domain containing 22 2.71568
CLCC1 chloride channel CLIC-like 1 2.6501
HEXB hexosaminidase B (beta polypeptide) 2.64504
CEP72 centrosomal protein 72kDa 2.60478
AQP7 aquaporin 7 2.60199
OLIG1 oligodendrocyte transcription factor 1 2.59287
WDR46 WD repeat domain 46 2.5731
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 2.55259
IRGQ immunity-related GTPase family, Q 2.55054
ALKBH8 alkB, alkylation repair homolog 8 (E. coli) 2.49013
RETNLB resistin like beta 2.46354
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 2.45673
CAAP1 caspase activity and apoptosis inhibitor 1 2.4478
SUMF2 sulfatase modifying factor 2 2.44163
SPRED2 sprouty-related, EVH1 domain containing 2 2.42904
EFCAB14 EF-hand calcium binding domain 14 2.42102
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.41649
GPR12 G protein-coupled receptor 12 2.41286
AVIL advillin 2.35266
TRPM3 transient receptor potential cation channel, subfamily M, member 3 2.3461
OR5B21 olfactory receptor, family 5, subfamily B, member 21 2.32194
IFT122 intraflagellar transport 122 2.29814
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.2965
ARMC8 armadillo repeat containing 8 2.29386
TMEM8A transmembrane protein 8A 2.28978
SMS spermine synthase 2.27251
SOX18 SRY (sex determining region Y)-box 18 2.27034
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 2.26784
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 2.25983
BIN3 bridging integrator 3 2.25139
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.24121
OR4D10 olfactory receptor, family 4, subfamily D, member 10 2.23513
MSRB2 methionine sulfoxide reductase B2 2.22539
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 2.22512
USF1 upstream transcription factor 1 2.21581
H1FX H1 histone family, member X 2.20736
RFT1 RFT1 homolog (S. cerevisiae) 2.20371
RGS2 regulator of G-protein signaling 2 2.19576
FAM3B family with sequence similarity 3, member B 2.18684
KLK3 kallikrein-related peptidase 3 2.18378
FANCM Fanconi anemia, complementation group M 2.17611
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.17132
KANSL2 KAT8 regulatory NSL complex subunit 2 2.16842
PARD6G par-6 family cell polarity regulator gamma 2.16157
IFT52 intraflagellar transport 52 2.15978
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.15234
IRAK4 interleukin-1 receptor-associated kinase 4 2.13658
KRTAP4-3 keratin associated protein 4-3 2.13529
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.12291
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.1227
ACBD5 acyl-CoA binding domain containing 5 2.12033
CXCR3 chemokine (C-X-C motif) receptor 3 2.11205
OR6C6 olfactory receptor, family 6, subfamily C, member 6 2.11164
SH2B3 SH2B adaptor protein 3 2.11006
RFX1 regulatory factor X, 1 (influences HLA class II expression) 2.10436
KRTCAP3 keratinocyte associated protein 3 2.09665
MAP10 microtubule-associated protein 10 2.07496
KLK14 kallikrein-related peptidase 14 2.07253
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) 2.06881
ZFP42 ZFP42 zinc finger protein 2.06548
CAMK2D calcium/calmodulin-dependent protein kinase II delta 2.06473
POGZ pogo transposable element with ZNF domain 2.04716
PHF14 PHD finger protein 14 2.04321
PRDX3 peroxiredoxin 3 2.04209
EPHA1 EPH receptor A1 2.04161
ZNF536 zinc finger protein 536 2.04063
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.03225
DACH2 dachshund family transcription factor 2 2.0198
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 2.01937
CDH26 cadherin 26 2.01137
ZNRF3 zinc and ring finger 3 2.00789
SPTSSA serine palmitoyltransferase, small subunit A 1.99659
EDAR ectodysplasin A receptor 1.99224
C15ORF48 chromosome 15 open reading frame 48 1.99169
NCAPG2 non-SMC condensin II complex, subunit G2 1.97309
FAM160A1 family with sequence similarity 160, member A1 1.97136
CCDC64B coiled-coil domain containing 64B 1.95931
CBX5 chromobox homolog 5 1.95697
SHF Src homology 2 domain containing F 1.95411
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C 1.93971
TRPM8 transient receptor potential cation channel, subfamily M, member 8 1.93481
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 1.92609
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 1.92525
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1.92445
HRASLS HRAS-like suppressor 1.92215
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.91649
TGFA transforming growth factor, alpha 1.91643
CCT7 chaperonin containing TCP1, subunit 7 (eta) 1.90928
KRBA1 KRAB-A domain containing 1 1.90918
PBX1 pre-B-cell leukemia homeobox 1 1.90762
TGDS TDP-glucose 4,6-dehydratase 1.90702
CCDC85B coiled-coil domain containing 85B 1.90148
ATHL1 ATH1, acid trehalase-like 1 (yeast) 1.8963
C11ORF31 chromosome 11 open reading frame 31 1.89209
C1ORF174 chromosome 1 open reading frame 174 1.88463
IDO2 indoleamine 2,3-dioxygenase 2 1.88171
HIPK1 homeodomain interacting protein kinase 1 1.86261
CLYBL citrate lyase beta like 1.86071
MTUS1 microtubule associated tumor suppressor 1 1.85965
GALR2 galanin receptor 2 1.85341
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.8519
DDB2 damage-specific DNA binding protein 2, 48kDa 1.85169
SEC23A Sec23 homolog A (S. cerevisiae) 1.85161
CCNB1 cyclin B1 1.8458
COL3A1 collagen, type III, alpha 1 1.84406
TYK2 tyrosine kinase 2 1.84084
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.83542
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.8353
CDC20 cell division cycle 20 1.83372
CPA2 carboxypeptidase A2 (pancreatic) 1.83299
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 1.8322
VPRBP Vpr (HIV-1) binding protein 1.83102
SLTM SAFB-like, transcription modulator 1.82605
TMEM143 transmembrane protein 143 1.8223
TRIOBP TRIO and F-actin binding protein 1.81725
AGR3 anterior gradient 3 1.81284
RARG retinoic acid receptor, gamma 1.8124
PABPC1 poly(A) binding protein, cytoplasmic 1 1.8109
PRDM1 PR domain containing 1, with ZNF domain 1.81016
GGCT gamma-glutamylcyclotransferase 1.80661
TMEM35 transmembrane protein 35 1.80241
ALOX15B arachidonate 15-lipoxygenase, type B 1.79754
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.79661
PIWIL2 piwi-like RNA-mediated gene silencing 2 1.79456
DUSP4 dual specificity phosphatase 4 1.79367
KCTD12 potassium channel tetramerization domain containing 12 1.78577
SWAP70 SWAP switching B-cell complex 70kDa subunit 1.78206
ZNF799 zinc finger protein 799 1.78193
TPRG1L tumor protein p63 regulated 1-like 1.78163
PNMA2 paraneoplastic Ma antigen 2 1.77597
MEX3C mex-3 RNA binding family member C 1.77153
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 1.77054
TASP1 taspase, threonine aspartase, 1 1.76817
CDH22 cadherin 22, type 2 1.76025
CARD10 caspase recruitment domain family, member 10 1.75335
SLAIN1 SLAIN motif family, member 1 1.75164
GHRHR growth hormone releasing hormone receptor 1.74686
GPATCH3 G patch domain containing 3 1.74466
CDC45 cell division cycle 45 1.74434
ADD1 adducin 1 (alpha) 1.74399
NOX1 NADPH oxidase 1 1.73926
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.73464
CDH8 cadherin 8, type 2 1.7324
AMER2 APC membrane recruitment protein 2 1.73027
KRT82 keratin 82, type II 1.72904
ZNF48 zinc finger protein 48 1.72053
LYPLAL1 lysophospholipase-like 1 1.71839
WNT9B wingless-type MMTV integration site family, member 9B 1.7162
MINPP1 multiple inositol-polyphosphate phosphatase 1 1.71497
BGLAP bone gamma-carboxyglutamate (gla) protein 1.71447
IL1R1 interleukin 1 receptor, type I 1.70955
PRC1 protein regulator of cytokinesis 1 1.70841
MAPK11 mitogen-activated protein kinase 11 1.70432
DCLK2 doublecortin-like kinase 2 1.70358
DAAM2 dishevelled associated activator of morphogenesis 2 1.70156
HIC2 hypermethylated in cancer 2 1.70026
GPM6A glycoprotein M6A 1.69902
TTC24 tetratricopeptide repeat domain 24 1.6965
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 1.69572
BST1 bone marrow stromal cell antigen 1 1.69223
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.68847
A3GALT2 alpha 1,3-galactosyltransferase 2 1.68544
ADHFE1 alcohol dehydrogenase, iron containing, 1 1.68381
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 1.67742
RORA RAR-related orphan receptor A 1.67637
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 1.67589
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.67411
DBF4 DBF4 zinc finger 1.66888
ODF2 outer dense fiber of sperm tails 2 1.66675
TWISTNB TWIST neighbor 1.66627
PDRG1 p53 and DNA-damage regulated 1 1.6658
PDE3A phosphodiesterase 3A, cGMP-inhibited 1.66057
MYOD1 myogenic differentiation 1 1.65353
GRM8 glutamate receptor, metabotropic 8 1.65144
CD96 CD96 molecule 1.6497
HIST1H1T histone cluster 1, H1t 1.64709
OR4C3 olfactory receptor, family 4, subfamily C, member 3 1.64399
GDI2 GDP dissociation inhibitor 2 1.64056
ARID5A AT rich interactive domain 5A (MRF1-like) 1.63433
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 1.6297
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2 1.62877
C16ORF45 chromosome 16 open reading frame 45 1.62853
CD163 CD163 molecule 1.62817
COPZ2 coatomer protein complex, subunit zeta 2 1.62805
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 1.628
ZNF25 zinc finger protein 25 1.62708
DCAF11 DDB1 and CUL4 associated factor 11 1.62089
ZCWPW1 zinc finger, CW type with PWWP domain 1 1.62051
PLAGL1 pleiomorphic adenoma gene-like 1 1.62014
LRRC19 leucine rich repeat containing 19 1.61793
SPATA7 spermatogenesis associated 7 1.61729
ROPN1L rhophilin associated tail protein 1-like 1.61153
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 1.6085
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.5997
DSC1 desmocollin 1 1.599
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 1.59833
GSG2 germ cell associated 2 (haspin) 1.59611
SSPN sarcospan 1.5913
FAM171B family with sequence similarity 171, member B 1.58925
NMS neuromedin S 1.58899
TEX101 testis expressed 101 1.58801
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 1.58756
TMEM74 transmembrane protein 74 1.58451
SELV selenoprotein V 1.58442
FAM149B1 family with sequence similarity 149, member B1 1.58015
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 1.57913
C1S complement component 1, s subcomponent 1.57488
CORO2A coronin, actin binding protein, 2A 1.57432
OLFML1 olfactomedin-like 1 1.57329
CD300A CD300a molecule 1.56837
FBXO40 F-box protein 40 1.56733
TMEM102 transmembrane protein 102 1.56596
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.56464
PTCD3 pentatricopeptide repeat domain 3 1.55456
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 1.55335
FLOT2 flotillin 2 1.55276
ESR2 estrogen receptor 2 (ER beta) 1.55236
RPH3AL rabphilin 3A-like (without C2 domains) 1.5523
NME5 NME/NM23 family member 5 1.55195
VAV2 vav 2 guanine nucleotide exchange factor 1.54829
ELAVL3 ELAV like neuron-specific RNA binding protein 3 1.54598
WDR35 WD repeat domain 35 1.54454
CSHL1 chorionic somatomammotropin hormone-like 1 1.53843
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 1.53836
NPVF neuropeptide VF precursor 1.53714
CCDC180 coiled-coil domain containing 180 1.53605
PNPO pyridoxamine 5'-phosphate oxidase 1.53249
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 1.53199
SLC7A14 solute carrier family 7, member 14 1.53118
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.53014
RP1 retinitis pigmentosa 1 (autosomal dominant) 1.52984
TRPM6 transient receptor potential cation channel, subfamily M, member 6 1.52887
KRT7 keratin 7, type II 1.52695
WNT10A wingless-type MMTV integration site family, member 10A 1.52621
OR52E8 olfactory receptor, family 52, subfamily E, member 8 1.52288
FOXJ3 forkhead box J3 1.52088
MED23 mediator complex subunit 23 1.51893
UBE2S ubiquitin-conjugating enzyme E2S 1.51747
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.5157
GTF2B general transcription factor IIB 1.51323
NFE2L2 nuclear factor, erythroid 2-like 2 1.5127
CXCR6 chemokine (C-X-C motif) receptor 6 1.50793
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.50747
CDCA3 cell division cycle associated 3 1.50618
UBAC1 UBA domain containing 1 1.50365
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 1.50293
C11ORF16 chromosome 11 open reading frame 16 1.5022
LPPR1 lipid phosphate phosphatase-related protein type 1 1.50151
SHCBP1 SHC SH2-domain binding protein 1 1.49854
USP10 ubiquitin specific peptidase 10 1.49682
KDM4D lysine (K)-specific demethylase 4D 1.49621
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.49588
BCAS1 breast carcinoma amplified sequence 1 1.4951
COL25A1 collagen, type XXV, alpha 1 1.49496
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.49327
C3ORF58 chromosome 3 open reading frame 58 1.49221
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 1.49152
PNPLA2 patatin-like phospholipase domain containing 2 1.48814
MMD2 monocyte to macrophage differentiation-associated 2 1.48744
NPPA natriuretic peptide A 1.48666
IFNE interferon, epsilon 1.48606
CENPI centromere protein I 1.48361
ITPKB inositol-trisphosphate 3-kinase B 1.48156
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.47949
PDE5A phosphodiesterase 5A, cGMP-specific 1.4791
GAPVD1 GTPase activating protein and VPS9 domains 1 1.47886
NKAPL NFKB activating protein-like 1.47859
CD99L2 CD99 molecule-like 2 1.4768
SSMEM1 serine-rich single-pass membrane protein 1 1.47002
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 1.46987
ZNF317 zinc finger protein 317 1.46688
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 1.46616
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 1.46507
CLVS2 clavesin 2 1.46489
MBIP MAP3K12 binding inhibitory protein 1 1.46079
ITM2B integral membrane protein 2B 1.4602
FAM47E family with sequence similarity 47, member E 1.45896
CLEC3B C-type lectin domain family 3, member B 1.4577
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 1.45493
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 1.45252
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 1.45247
CNTRL centriolin 1.45135
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 1.44945
JMJD8 jumonji domain containing 8 1.44791
ANKRD44 ankyrin repeat domain 44 1.44357
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.44326
FAM221B family with sequence similarity 221, member B 1.44301
ZMYND8 zinc finger, MYND-type containing 8 1.44186
AGO3 argonaute RISC catalytic component 3 1.43998

decreased expression

Symbol Name Standardized Value
MINK1 misshapen-like kinase 1 -4.40376
CD300LD CD300 molecule-like family member d -4.23209
MOXD1 monooxygenase, DBH-like 1 -3.78585
SLC38A9 solute carrier family 38, member 9 -3.62884
RXRG retinoid X receptor, gamma -3.25108
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -3.16103
C7ORF25 chromosome 7 open reading frame 25 -3.13849
MBP myelin basic protein -3.10845
OR6C65 olfactory receptor, family 6, subfamily C, member 65 -3.07676
KHNYN KH and NYN domain containing -3.01256
IL17B interleukin 17B -2.84489
CTNND1 catenin (cadherin-associated protein), delta 1 -2.82316
MAGEB1 melanoma antigen family B1 -2.72003
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.71098
GFRA3 GDNF family receptor alpha 3 -2.61851
RTKN rhotekin -2.5801
SON SON DNA binding protein -2.57223
SLC26A7 solute carrier family 26 (anion exchanger), member 7 -2.56477
CASC4 cancer susceptibility candidate 4 -2.5327
UCK2 uridine-cytidine kinase 2 -2.52286
LRRTM3 leucine rich repeat transmembrane neuronal 3 -2.51636
MYOT myotilin -2.51571
EYA3 EYA transcriptional coactivator and phosphatase 3 -2.49041
LMX1A LIM homeobox transcription factor 1, alpha -2.45653
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -2.45568
STMN4 stathmin-like 4 -2.45411
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 -2.45406
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) -2.44801
LOC100506944 uncharacterized LOC100506944 -2.43442
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.40217
FAM49A family with sequence similarity 49, member A -2.39486
LIMS1 LIM and senescent cell antigen-like domains 1 -2.38656
SYT10 synaptotagmin X -2.3786
UNKL unkempt family zinc finger-like -2.35339
GRIPAP1 GRIP1 associated protein 1 -2.3464
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) -2.34121
CCDC117 coiled-coil domain containing 117 -2.32676
CCR1 chemokine (C-C motif) receptor 1 -2.32139
CA6 carbonic anhydrase VI -2.31756
OR8H2 olfactory receptor, family 8, subfamily H, member 2 -2.31196
HSPA4 heat shock 70kDa protein 4 -2.30948
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 -2.30173
ILF3 interleukin enhancer binding factor 3, 90kDa -2.29728
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -2.29478
TYMS thymidylate synthetase -2.28657
SKIL SKI-like proto-oncogene -2.25409
RAB3A RAB3A, member RAS oncogene family -2.25095
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -2.24683
SIX5 SIX homeobox 5 -2.24041
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 -2.22751
OR4K2 olfactory receptor, family 4, subfamily K, member 2 -2.22208
FAM118B family with sequence similarity 118, member B -2.19314
ADCK1 aarF domain containing kinase 1 -2.17553
WDR26 WD repeat domain 26 -2.17541
RIC8B RIC8 guanine nucleotide exchange factor B -2.17091
BCL2L10 BCL2-like 10 (apoptosis facilitator) -2.17046
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -2.15869
PAX9 paired box 9 -2.15754
FSHB follicle stimulating hormone, beta polypeptide -2.13667
OR8G1 olfactory receptor, family 8, subfamily G, member 1 (gene/pseudogene) -2.13215
ASB1 ankyrin repeat and SOCS box containing 1 -2.12384
CH25H cholesterol 25-hydroxylase -2.12164
GAREM GRB2 associated, regulator of MAPK1 -2.12064
VSIG1 V-set and immunoglobulin domain containing 1 -2.11121
CTSC cathepsin C -2.1033
DPH5 diphthamide biosynthesis 5 -2.10164
KLHL28 kelch-like family member 28 -2.07656
MDM1 Mdm1 nuclear protein homolog (mouse) -2.07561
ETV2 ets variant 2 -2.06316
YBX3 Y box binding protein 3 -2.06266
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) -2.0457
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -2.04312
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.03342
GSK3A glycogen synthase kinase 3 alpha -2.03145
PLK1 polo-like kinase 1 -2.03061
OPN5 opsin 5 -2.02821
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -2.02505
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.0188
SELE selectin E -2.01541
ANXA1 annexin A1 -2.01522
SPO11 SPO11 meiotic protein covalently bound to DSB -2.00348
KLC2 kinesin light chain 2 -1.99675
JAM3 junctional adhesion molecule 3 -1.98776
RAD51AP1 RAD51 associated protein 1 -1.98442
RNF183 ring finger protein 183 -1.97541
OR6B1 olfactory receptor, family 6, subfamily B, member 1 -1.9732
RABGGTA Rab geranylgeranyltransferase, alpha subunit -1.95622
EPSTI1 epithelial stromal interaction 1 (breast) -1.9535
PRSS3 protease, serine, 3 -1.9416
KRT79 keratin 79, type II -1.94049
USP39 ubiquitin specific peptidase 39 -1.93408
PXDC1 PX domain containing 1 -1.93231
PUS7 pseudouridylate synthase 7 (putative) -1.93164
OGN osteoglycin -1.92666
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -1.92199
COPS5 COP9 signalosome subunit 5 -1.92157
RARB retinoic acid receptor, beta -1.9197
TECPR2 tectonin beta-propeller repeat containing 2 -1.91274
RABGAP1L RAB GTPase activating protein 1-like -1.90685
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -1.90293
CRMP1 collapsin response mediator protein 1 -1.89109
CDC27 cell division cycle 27 -1.89056
HAPLN3 hyaluronan and proteoglycan link protein 3 -1.88453
DENND6A DENN/MADD domain containing 6A -1.87914
TXNDC11 thioredoxin domain containing 11 -1.8761
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -1.85921
PPP1R12C protein phosphatase 1, regulatory subunit 12C -1.85593
NUP37 nucleoporin 37kDa -1.85237
CLCN5 chloride channel, voltage-sensitive 5 -1.85058
JTB jumping translocation breakpoint -1.84645
OR52A1 olfactory receptor, family 52, subfamily A, member 1 -1.84621
ASIC2 acid sensing (proton gated) ion channel 2 -1.8432
MISP mitotic spindle positioning -1.83575
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -1.83406
USP45 ubiquitin specific peptidase 45 -1.83187
NECAP1 NECAP endocytosis associated 1 -1.82661
LDHC lactate dehydrogenase C -1.82651
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) -1.82272
TSPAN6 tetraspanin 6 -1.81113
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 -1.81113
TMEM126A transmembrane protein 126A -1.81059
COBL cordon-bleu WH2 repeat protein -1.8105
AP1M2 adaptor-related protein complex 1, mu 2 subunit -1.80868
AKAP2 A kinase (PRKA) anchor protein 2 -1.80552
PCNXL3 pecanex-like 3 (Drosophila) -1.79596
TMCO3 transmembrane and coiled-coil domains 3 -1.79578
BPIFA3 BPI fold containing family A, member 3 -1.79527
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -1.793
NPY1R neuropeptide Y receptor Y1 -1.7919
MAP1B microtubule-associated protein 1B -1.78904
TNNI2 troponin I type 2 (skeletal, fast) -1.78448
PRPH2 peripherin 2 (retinal degeneration, slow) -1.77008
OPA1 optic atrophy 1 (autosomal dominant) -1.7687
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -1.76329
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -1.76233
DMD dystrophin -1.7579
ZNF239 zinc finger protein 239 -1.75708
SOX7 SRY (sex determining region Y)-box 7 -1.75569
TBX2 T-box 2 -1.75569
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -1.74791
CCDC155 coiled-coil domain containing 155 -1.7471
MOB3C MOB kinase activator 3C -1.74626
MYH1 myosin, heavy chain 1, skeletal muscle, adult -1.73614
VNN1 vanin 1 -1.73427
SPIC Spi-C transcription factor (Spi-1/PU.1 related) -1.7337
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -1.72973
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -1.72083
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -1.71676
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -1.71405
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -1.71354
PLA2G2E phospholipase A2, group IIE -1.71227
OR6A2 olfactory receptor, family 6, subfamily A, member 2 -1.71015
TRIM35 tripartite motif containing 35 -1.70941
CX3CL1 chemokine (C-X3-C motif) ligand 1 -1.70696
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -1.70554
ALCAM activated leukocyte cell adhesion molecule -1.70281
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -1.6973
GPR137B G protein-coupled receptor 137B -1.69599
LPPR2 lipid phosphate phosphatase-related protein type 2 -1.69513
RNF220 ring finger protein 220 -1.6943
LGSN lengsin, lens protein with glutamine synthetase domain -1.69079
FGD4 FYVE, RhoGEF and PH domain containing 4 -1.69039
DRD3 dopamine receptor D3 -1.68551
WNT16 wingless-type MMTV integration site family, member 16 -1.6847
WBP4 WW domain binding protein 4 -1.68366
EPC1 enhancer of polycomb homolog 1 (Drosophila) -1.68238
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 -1.67962
OPN4 opsin 4 -1.67592
FBXL18 F-box and leucine-rich repeat protein 18 -1.67537
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -1.6687
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -1.66812
CHRND cholinergic receptor, nicotinic, delta (muscle) -1.66255
SRSF3 serine/arginine-rich splicing factor 3 -1.66233
UNC13D unc-13 homolog D (C. elegans) -1.66035
FOXF2 forkhead box F2 -1.65797
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -1.65129
BMP2K BMP2 inducible kinase -1.64823
CLDN6 claudin 6 -1.6479
ZNF397 zinc finger protein 397 -1.64514
NAPSA napsin A aspartic peptidase -1.64501
NIN ninein (GSK3B interacting protein) -1.64341
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -1.64196
C3ORF14 chromosome 3 open reading frame 14 -1.64193
SVIL supervillin -1.63882
DLAT dihydrolipoamide S-acetyltransferase -1.6363
GPR149 G protein-coupled receptor 149 -1.63537
EGLN2 egl-9 family hypoxia-inducible factor 2 -1.63484
PNMA3 paraneoplastic Ma antigen 3 -1.63334
ITSN2 intersectin 2 -1.63269
CDK20 cyclin-dependent kinase 20 -1.62997
TBX22 T-box 22 -1.62803
PRKG1 protein kinase, cGMP-dependent, type I -1.62571
CDKN2AIP CDKN2A interacting protein -1.61738
HIRIP3 HIRA interacting protein 3 -1.61547
SHOX2 short stature homeobox 2 -1.61328
TTLL10 tubulin tyrosine ligase-like family member 10 -1.61105
CEP57 centrosomal protein 57kDa -1.61005
CRLS1 cardiolipin synthase 1 -1.60993
BACE1 beta-site APP-cleaving enzyme 1 -1.60437
OTP orthopedia homeobox -1.6027
CPNE3 copine III -1.60243
CNN2 calponin 2 -1.60161
CUZD1 CUB and zona pellucida-like domains 1 -1.60142
PNN pinin, desmosome associated protein -1.60032
MPO myeloperoxidase -1.60008
ZNF8 zinc finger protein 8 -1.60005
CORO6 coronin 6 -1.59898
CD5 CD5 molecule -1.5982
TLE6 transducin-like enhancer of split 6 -1.5973
SEC23IP SEC23 interacting protein -1.59672
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase -1.59549
TSSC4 tumor suppressing subtransferable candidate 4 -1.59503
POU2F1 POU class 2 homeobox 1 -1.59368
CYSLTR2 cysteinyl leukotriene receptor 2 -1.59238
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 -1.59106
S100A10 S100 calcium binding protein A10 -1.59007
PITPNM3 PITPNM family member 3 -1.58777
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) -1.58679
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -1.58642
SPAG4 sperm associated antigen 4 -1.58341
AMIGO3 adhesion molecule with Ig-like domain 3 -1.58323
CENPQ centromere protein Q -1.58241
CYBB cytochrome b-245, beta polypeptide -1.5815
HDAC2 histone deacetylase 2 -1.58077
METTL24 methyltransferase like 24 -1.57571
CACYBP calcyclin binding protein -1.57025
OSTN osteocrin -1.56838
PALLD palladin, cytoskeletal associated protein -1.56836
MRPL34 mitochondrial ribosomal protein L34 -1.56709
SPAG17 sperm associated antigen 17 -1.5659
INSL5 insulin-like 5 -1.56505
SGOL1 shugoshin-like 1 (S. pombe) -1.56262
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -1.55778
GABRD gamma-aminobutyric acid (GABA) A receptor, delta -1.55765
GRK4 G protein-coupled receptor kinase 4 -1.5566
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -1.55578
PAN3 PAN3 poly(A) specific ribonuclease subunit -1.55255
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -1.55201
ESR1 estrogen receptor 1 -1.55172
ZNF443 zinc finger protein 443 -1.55064
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -1.55061
MR1 major histocompatibility complex, class I-related -1.54921
ARL10 ADP-ribosylation factor-like 10 -1.54615
USP6NL USP6 N-terminal like -1.54499
BRICD5 BRICHOS domain containing 5 -1.54108
ZNF287 zinc finger protein 287 -1.5409
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 -1.53887
NUP85 nucleoporin 85kDa -1.53845
TFE3 transcription factor binding to IGHM enhancer 3 -1.53841
SLC25A27 solute carrier family 25, member 27 -1.53803
GMCL1 germ cell-less, spermatogenesis associated 1 -1.53707
NGB neuroglobin -1.53451
SERTM1 serine-rich and transmembrane domain containing 1 -1.52724
ATL1 atlastin GTPase 1 -1.52649
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -1.52599
WDR36 WD repeat domain 36 -1.52592
ZDHHC18 zinc finger, DHHC-type containing 18 -1.52186
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -1.5213
TMEM229A transmembrane protein 229A -1.51779
GANAB glucosidase, alpha; neutral AB -1.51753
FBLN5 fibulin 5 -1.51525
NINJ2 ninjurin 2 -1.51368
TEAD4 TEA domain family member 4 -1.50791
HSPB2 heat shock 27kDa protein 2 -1.50651
VWA2 von Willebrand factor A domain containing 2 -1.5053
IGFBPL1 insulin-like growth factor binding protein-like 1 -1.50218
TPO thyroid peroxidase -1.50206
TRIM66 tripartite motif containing 66 -1.50056
UNC5D unc-5 homolog D (C. elegans) -1.50016
EMG1 EMG1 N1-specific pseudouridine methyltransferase -1.49365
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -1.49361
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -1.49246
PCDHB1 protocadherin beta 1 -1.49166
BDNF brain-derived neurotrophic factor -1.48792
CPT1B carnitine palmitoyltransferase 1B (muscle) -1.48526
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.48152
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -1.48093
KLRD1 killer cell lectin-like receptor subfamily D, member 1 -1.4808
ARSG arylsulfatase G -1.47954
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -1.47929
ADD3 adducin 3 (gamma) -1.47522
INPP1 inositol polyphosphate-1-phosphatase -1.47479
NAV2 neuron navigator 2 -1.47454
SSBP3 single stranded DNA binding protein 3 -1.47414
C18ORF25 chromosome 18 open reading frame 25 -1.47275
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 -1.47142
PARP2 poly (ADP-ribose) polymerase 2 -1.46804
FGFR1OP FGFR1 oncogene partner -1.46761
MFRP membrane frizzled-related protein -1.4665
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -1.46626
SNED1 sushi, nidogen and EGF-like domains 1 -1.46622
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -1.46328
ASPH aspartate beta-hydroxylase -1.46293
JMJD6 jumonji domain containing 6 -1.46143
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -1.45878
CLEC4C C-type lectin domain family 4, member C -1.45799
CSRP2BP CSRP2 binding protein -1.45695
PHOX2A paired-like homeobox 2a -1.45654
AKNAD1 AKNA domain containing 1 -1.45301
GZMM granzyme M (lymphocyte met-ase 1) -1.45264