EGFR_druginhibition_82_GSE27638 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27638
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Genes

600 genes differentially expressed following the EGFR_druginhibition_82_GSE27638 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
GPR155 G protein-coupled receptor 155 4.95132
TMEM86A transmembrane protein 86A 3.6061
MYL7 myosin, light chain 7, regulatory 3.49287
MSTO1 misato 1, mitochondrial distribution and morphology regulator 3.37908
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 3.36689
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 3.34571
RBP3 retinol binding protein 3, interstitial 3.11752
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2 3.01623
ELOVL3 ELOVL fatty acid elongase 3 3.00106
SLITRK2 SLIT and NTRK-like family, member 2 2.90148
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.86389
NTN3 netrin 3 2.72544
ZNF202 zinc finger protein 202 2.71781
TRADD TNFRSF1A-associated via death domain 2.70419
RASAL1 RAS protein activator like 1 (GAP1 like) 2.66024
KIRREL kin of IRRE like (Drosophila) 2.64957
KRT76 keratin 76, type II 2.57785
DSTN destrin (actin depolymerizing factor) 2.56608
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 2.5539
CYTL1 cytokine-like 1 2.52696
TOR4A torsin family 4, member A 2.50861
PVALB parvalbumin 2.4955
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 2.44639
NODAL nodal growth differentiation factor 2.42658
IGFLR1 IGF-like family receptor 1 2.42544
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 2.41368
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 2.34926
GEMIN2 gem (nuclear organelle) associated protein 2 2.31216
MYLK myosin light chain kinase 2.27593
RAB36 RAB36, member RAS oncogene family 2.25141
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.24284
SYT11 synaptotagmin XI 2.226
LY6G5B lymphocyte antigen 6 complex, locus G5B 2.16598
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.16214
SSTR5 somatostatin receptor 5 2.15252
FAM49A family with sequence similarity 49, member A 2.1484
SEC63 SEC63 homolog (S. cerevisiae) 2.13289
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.12038
SPATA18 spermatogenesis associated 18 2.1122
ADCY7 adenylate cyclase 7 2.09049
CELA3B chymotrypsin-like elastase family, member 3B 2.06724
ZNF644 zinc finger protein 644 2.05991
POMK protein-O-mannose kinase 2.05701
DPCR1 diffuse panbronchiolitis critical region 1 2.0563
CPNE7 copine VII 2.04359
ZBTB49 zinc finger and BTB domain containing 49 2.03743
ZCCHC14 zinc finger, CCHC domain containing 14 2.037
STAT5A signal transducer and activator of transcription 5A 2.01465
GALR3 galanin receptor 3 1.98702
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1.9866
ZFP37 ZFP37 zinc finger protein 1.96364
MKRN3 makorin ring finger protein 3 1.9604
ATG14 autophagy related 14 1.95269
GDAP1 ganglioside induced differentiation associated protein 1 1.94685
IQCF1 IQ motif containing F1 1.94538
SKA2 spindle and kinetochore associated complex subunit 2 1.94189
CNTNAP5 contactin associated protein-like 5 1.92773
SLIT1 slit homolog 1 (Drosophila) 1.91116
TOP1 topoisomerase (DNA) I 1.87655
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 1.86212
CDC40 cell division cycle 40 1.85652
CCDC126 coiled-coil domain containing 126 1.84621
TCTN3 tectonic family member 3 1.84386
FAM181B family with sequence similarity 181, member B 1.83513
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 1.82605
PRL prolactin 1.82381
PAX1 paired box 1 1.81379
CDC14B cell division cycle 14B 1.81084
ZBTB8B zinc finger and BTB domain containing 8B 1.80794
PEX10 peroxisomal biogenesis factor 10 1.80736
LHFPL1 lipoma HMGIC fusion partner-like 1 1.80712
INHBB inhibin, beta B 1.80407
FNBP1 formin binding protein 1 1.79038
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.78599
SUN1 Sad1 and UNC84 domain containing 1 1.78528
CCDC60 coiled-coil domain containing 60 1.78501
PRPF31 pre-mRNA processing factor 31 1.76893
FAM107B family with sequence similarity 107, member B 1.76216
ATCAY ataxia, cerebellar, Cayman type 1.76134
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 1.75963
PSIP1 PC4 and SFRS1 interacting protein 1 1.75148
CLEC3A C-type lectin domain family 3, member A 1.74372
TGDS TDP-glucose 4,6-dehydratase 1.74188
HYAL4 hyaluronoglucosaminidase 4 1.73222
GFRA1 GDNF family receptor alpha 1 1.72453
TNPO2 transportin 2 1.71325
CSF3 colony stimulating factor 3 (granulocyte) 1.71266
LGI1 leucine-rich, glioma inactivated 1 1.70775
TDRD7 tudor domain containing 7 1.70494
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 1.70316
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 1.70259
CYB5RL cytochrome b5 reductase-like 1.70214
WNT11 wingless-type MMTV integration site family, member 11 1.70159
LRRC29 leucine rich repeat containing 29 1.70095
GATA6 GATA binding protein 6 1.69815
NLGN1 neuroligin 1 1.69512
AVPR1B arginine vasopressin receptor 1B 1.69094
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 1.65952
AMIGO3 adhesion molecule with Ig-like domain 3 1.65796
TEKT2 tektin 2 (testicular) 1.64863
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 1.6434
ATF7IP2 activating transcription factor 7 interacting protein 2 1.64333
IL13RA1 interleukin 13 receptor, alpha 1 1.63264
RPTOR regulatory associated protein of MTOR, complex 1 1.62262
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 1.61729
MAP2K7 mitogen-activated protein kinase kinase 7 1.61419
TMEM154 transmembrane protein 154 1.61196
LMOD1 leiomodin 1 (smooth muscle) 1.60273
MTX1 metaxin 1 1.60008
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1.59808
AHI1 Abelson helper integration site 1 1.59696
BRMS1L breast cancer metastasis-suppressor 1-like 1.59381
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 1.59146
NLK nemo-like kinase 1.59052
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.57845
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.57827
TEX101 testis expressed 101 1.57394
PROX2 prospero homeobox 2 1.56936
ZC2HC1A zinc finger, C2HC-type containing 1A 1.56259
DSCR3 Down syndrome critical region 3 1.56231
FRS3 fibroblast growth factor receptor substrate 3 1.55647
GJC2 gap junction protein, gamma 2, 47kDa 1.55349
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 1.55292
CD300LF CD300 molecule-like family member f 1.55035
DPP10 dipeptidyl-peptidase 10 (non-functional) 1.54054
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.54049
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 1.53712
KLHL5 kelch-like family member 5 1.53656
AKNA AT-hook transcription factor 1.52527
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 1.51732
HOMEZ homeobox and leucine zipper encoding 1.4988
CATSPERG catsper channel auxiliary subunit gamma 1.49733
EIF5A2 eukaryotic translation initiation factor 5A2 1.49523
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 1.49233
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.48809
TMEM229B transmembrane protein 229B 1.487
ZNF438 zinc finger protein 438 1.4811
CLN5 ceroid-lipofuscinosis, neuronal 5 1.4742
HOXB1 homeobox B1 1.47236
SCG5 secretogranin V 1.47079
GRM8 glutamate receptor, metabotropic 8 1.46622
CEL carboxyl ester lipase 1.46598
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 1.46356
RYK receptor-like tyrosine kinase 1.46183
AHCYL1 adenosylhomocysteinase-like 1 1.45706
ASB13 ankyrin repeat and SOCS box containing 13 1.45521
FIGNL2 fidgetin-like 2 1.44655
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C 1.44514
OSR1 odd-skipped related transciption factor 1 1.44438
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.43786
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.4272
ARPP21 cAMP-regulated phosphoprotein, 21kDa 1.4255
SMAD7 SMAD family member 7 1.42445
BPIFA1 BPI fold containing family A, member 1 1.41914
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 1.41224
CRX cone-rod homeobox 1.4034
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.40278
SYNPO2L synaptopodin 2-like 1.39683
ZNF717 zinc finger protein 717 1.39545
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 1.39292
GDAP2 ganglioside induced differentiation associated protein 2 1.38376
KRT16 keratin 16, type I 1.36996
UHRF1BP1L UHRF1 binding protein 1-like 1.36707
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.36701
SUN2 Sad1 and UNC84 domain containing 2 1.35975
THOC3 THO complex 3 1.35754
USP28 ubiquitin specific peptidase 28 1.35374
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.35323
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 1.34597
ZDHHC24 zinc finger, DHHC-type containing 24 1.33703
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 1.33554
CHMP1A charged multivesicular body protein 1A 1.33447
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 1.32687
CILP2 cartilage intermediate layer protein 2 1.32599
TSHB thyroid stimulating hormone, beta 1.32354
TMC5 transmembrane channel-like 5 1.32007
NSF N-ethylmaleimide-sensitive factor 1.31755
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 1.31547
CDK6 cyclin-dependent kinase 6 1.31524
SYNJ2BP synaptojanin 2 binding protein 1.31436
ARMC1 armadillo repeat containing 1 1.31394
FAT4 FAT atypical cadherin 4 1.30551
HIST1H1T histone cluster 1, H1t 1.30522
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.30334
KRT82 keratin 82, type II 1.30273
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.29963
RSPRY1 ring finger and SPRY domain containing 1 1.29684
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 1.29402
FKTN fukutin 1.28882
TYRP1 tyrosinase-related protein 1 1.28385
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 1.28313
RGCC regulator of cell cycle 1.28172
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 1.28142
SFXN5 sideroflexin 5 1.28085
FGF9 fibroblast growth factor 9 1.27913
SASH3 SAM and SH3 domain containing 3 1.27859
FIGN fidgetin 1.27644
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.27513
DEPDC1B DEP domain containing 1B 1.27497
KERA keratocan 1.27344
WDR5 WD repeat domain 5 1.27289
TGM4 transglutaminase 4 1.27138
GDF10 growth differentiation factor 10 1.26961
TSGA10IP testis specific, 10 interacting protein 1.26909
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1.26812
PABPC1L poly(A) binding protein, cytoplasmic 1-like 1.26789
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 1.26742
LRRC73 leucine rich repeat containing 73 1.26478
NLGN3 neuroligin 3 1.26129
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.25513
TMEM229A transmembrane protein 229A 1.24322
GFOD1 glucose-fructose oxidoreductase domain containing 1 1.2402
TTC17 tetratricopeptide repeat domain 17 1.23796
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 1.23617
TTC5 tetratricopeptide repeat domain 5 1.23468
ACTL6B actin-like 6B 1.23155
UBASH3A ubiquitin associated and SH3 domain containing A 1.23057
NKX2-5 NK2 homeobox 5 1.22993
LINGO4 leucine rich repeat and Ig domain containing 4 1.22966
TMC2 transmembrane channel-like 2 1.22901
ESR1 estrogen receptor 1 1.2271
NCOA5 nuclear receptor coactivator 5 1.22559
CHN2 chimerin 2 1.22551
CDK20 cyclin-dependent kinase 20 1.21899
TMEM186 transmembrane protein 186 1.20973
TAAR9 trace amine associated receptor 9 (gene/pseudogene) 1.2049
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 1.20017
NTSR1 neurotensin receptor 1 (high affinity) 1.19851
GGN gametogenetin 1.19549
REST RE1-silencing transcription factor 1.19472
WDR20 WD repeat domain 20 1.19301
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.19248
NANOG Nanog homeobox 1.19123
GP5 glycoprotein V (platelet) 1.18848
TAAR1 trace amine associated receptor 1 1.18842
DOK7 docking protein 7 1.18767
MC3R melanocortin 3 receptor 1.18555
FAM83A family with sequence similarity 83, member A 1.18527
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 1.18303
TYR tyrosinase 1.17712
HSPB2 heat shock 27kDa protein 2 1.17678
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 1.17608
STYXL1 serine/threonine/tyrosine interacting-like 1 1.17311
CHD2 chromodomain helicase DNA binding protein 2 1.17206
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 1.17125
BMP6 bone morphogenetic protein 6 1.16942
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1.16939
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 1.16803
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.16753
TLCD2 TLC domain containing 2 1.1671
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 1.16644
UBP1 upstream binding protein 1 (LBP-1a) 1.1635
NUP210L nucleoporin 210kDa-like 1.16165
ZBTB2 zinc finger and BTB domain containing 2 1.16013
LIPI lipase, member I 1.15877
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 1.1573
HELLS helicase, lymphoid-specific 1.15319
LPPR2 lipid phosphate phosphatase-related protein type 2 1.15272
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 1.15211
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 1.14721
LIPN lipase, family member N 1.14269
SNUPN snurportin 1 1.1426
TBC1D25 TBC1 domain family, member 25 1.14121
SWSAP1 SWIM-type zinc finger 7 associated protein 1 1.13926
CLDN8 claudin 8 1.1389
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 1.13873
CREBL2 cAMP responsive element binding protein-like 2 1.1375
CHGA chromogranin A 1.13128
PTPRK protein tyrosine phosphatase, receptor type, K 1.12953
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 1.12643
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 1.12498
KREMEN1 kringle containing transmembrane protein 1 1.12461
SEPT9 septin 9 1.12252
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 1.12137
CELF5 CUGBP, Elav-like family member 5 1.1203
IL1RL2 interleukin 1 receptor-like 2 1.11991
PCDHGA12 protocadherin gamma subfamily A, 12 1.1168
DFNA5 deafness, autosomal dominant 5 1.11537
STAU1 staufen double-stranded RNA binding protein 1 1.11474
NKX3-1 NK3 homeobox 1 1.11213
DTX3L deltex 3 like, E3 ubiquitin ligase 1.11187
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.11134
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 1.10966
LRRTM4 leucine rich repeat transmembrane neuronal 4 1.10909
SNAI3 snail family zinc finger 3 1.10897
CLPS colipase, pancreatic 1.10803
STEAP2 STEAP family member 2, metalloreductase 1.10745
RRAD Ras-related associated with diabetes 1.1037
EML2 echinoderm microtubule associated protein like 2 1.10366
FGF8 fibroblast growth factor 8 (androgen-induced) 1.10349
TECRL trans-2,3-enoyl-CoA reductase-like 1.10312
FRMD4A FERM domain containing 4A 1.1021
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.10145
KRT24 keratin 24, type I 1.10016
ZSWIM4 zinc finger, SWIM-type containing 4 1.09774
SP6 Sp6 transcription factor 1.09398
MAST1 microtubule associated serine/threonine kinase 1 1.0931
HESX1 HESX homeobox 1 1.08595
NELL1 NEL-like 1 (chicken) 1.0844
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.08429

decreased expression

Symbol Name Standardized Value
IFT80 intraflagellar transport 80 -4.91338
CDK19 cyclin-dependent kinase 19 -3.77832
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -3.51916
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -3.1323
TRHDE thyrotropin-releasing hormone degrading enzyme -3.02532
GID8 GID complex subunit 8 -3.02407
PRSS42 protease, serine, 42 -2.85194
GNAS GNAS complex locus -2.77974
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 -2.77736
TMPRSS11D transmembrane protease, serine 11D -2.66474
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator -2.62501
HOXD3 homeobox D3 -2.61638
TCAIM T cell activation inhibitor, mitochondrial -2.57757
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -2.53862
MMEL1 membrane metallo-endopeptidase-like 1 -2.52043
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -2.47499
CNPY4 canopy FGF signaling regulator 4 -2.47064
ETNK1 ethanolamine kinase 1 -2.46721
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.45789
CSN2 casein beta -2.41551
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -2.39312
GFRA4 GDNF family receptor alpha 4 -2.38725
ACTBL2 actin, beta-like 2 -2.37458
NR2C2 nuclear receptor subfamily 2, group C, member 2 -2.33661
UBXN8 UBX domain protein 8 -2.29162
N4BP2L2 NEDD4 binding protein 2-like 2 -2.28495
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 -2.24549
FAM212B family with sequence similarity 212, member B -2.20995
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 -2.2041
S1PR1 sphingosine-1-phosphate receptor 1 -2.18039
CFAP52 cilia and flagella associated protein 52 -2.16973
SNN stannin -2.1546
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -2.13828
WDR33 WD repeat domain 33 -2.13589
HIPK4 homeodomain interacting protein kinase 4 -2.12781
UBE2O ubiquitin-conjugating enzyme E2O -2.09033
LRRD1 leucine-rich repeats and death domain containing 1 -2.0872
KIF18B kinesin family member 18B -2.0743
PHKG1 phosphorylase kinase, gamma 1 (muscle) -2.0525
KANSL3 KAT8 regulatory NSL complex subunit 3 -2.01682
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -2.00762
PDE4C phosphodiesterase 4C, cAMP-specific -1.99676
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -1.99496
CNTN2 contactin 2 (axonal) -1.94498
ZNF608 zinc finger protein 608 -1.93443
DBX2 developing brain homeobox 2 -1.934
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -1.91253
PKDREJ polycystin (PKD) family receptor for egg jelly -1.90606
ASIC5 acid sensing (proton gated) ion channel family member 5 -1.90484
RC3H2 ring finger and CCCH-type domains 2 -1.89922
XCR1 chemokine (C motif) receptor 1 -1.89063
RAB22A RAB22A, member RAS oncogene family -1.89034
NLRP6 NLR family, pyrin domain containing 6 -1.87406
ZNRF4 zinc and ring finger 4 -1.86311
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -1.86189
CRB1 crumbs family member 1, photoreceptor morphogenesis associated -1.86103
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 -1.84828
ATP7A ATPase, Cu++ transporting, alpha polypeptide -1.83273
GPR149 G protein-coupled receptor 149 -1.82966
TMEM222 transmembrane protein 222 -1.82037
GBA glucosidase, beta, acid -1.81971
TAAR8 trace amine associated receptor 8 -1.81204
RTBDN retbindin -1.80837
IFT46 intraflagellar transport 46 -1.79425
IL13 interleukin 13 -1.79178
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -1.78302
FERMT1 fermitin family member 1 -1.74283
IL1F10 interleukin 1 family, member 10 (theta) -1.73618
MMD2 monocyte to macrophage differentiation-associated 2 -1.73004
NECAB1 N-terminal EF-hand calcium binding protein 1 -1.72518
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 -1.70313
LY6G5C lymphocyte antigen 6 complex, locus G5C -1.70138
WDR47 WD repeat domain 47 -1.69229
SSTR2 somatostatin receptor 2 -1.68047
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 -1.67738
GPR119 G protein-coupled receptor 119 -1.67256
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -1.66173
HSPB9 heat shock protein, alpha-crystallin-related, B9 -1.65788
IQCF5 IQ motif containing F5 -1.65175
SMC1B structural maintenance of chromosomes 1B -1.64798
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -1.64707
SLC22A15 solute carrier family 22, member 15 -1.63913
TMEM182 transmembrane protein 182 -1.63272
ACOXL acyl-CoA oxidase-like -1.62376
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C -1.62196
SFSWAP splicing factor, suppressor of white-apricot family -1.60697
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -1.6025
KCNK5 potassium channel, two pore domain subfamily K, member 5 -1.59585
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.59533
LAMP3 lysosomal-associated membrane protein 3 -1.58767
PRM3 protamine 3 -1.56729
LBX2 ladybird homeobox 2 -1.56674
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 -1.55859
RTN4RL1 reticulon 4 receptor-like 1 -1.55747
POMC proopiomelanocortin -1.55503
HAPLN2 hyaluronan and proteoglycan link protein 2 -1.54605
THSD1 thrombospondin, type I, domain containing 1 -1.54065
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -1.52554
CUBN cubilin (intrinsic factor-cobalamin receptor) -1.52339
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.52098
TREML2 triggering receptor expressed on myeloid cells-like 2 -1.51481
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -1.51349
ZIC1 Zic family member 1 -1.50611
RSPH1 radial spoke head 1 homolog (Chlamydomonas) -1.50212
JMJD4 jumonji domain containing 4 -1.49108
PCDHGB7 protocadherin gamma subfamily B, 7 -1.4901
PANK4 pantothenate kinase 4 -1.48946
NXNL2 nucleoredoxin-like 2 -1.48566
GPR139 G protein-coupled receptor 139 -1.48227
STAC SH3 and cysteine rich domain -1.48155
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -1.47971
PRDM6 PR domain containing 6 -1.47769
DEPDC5 DEP domain containing 5 -1.47216
ORAOV1 oral cancer overexpressed 1 -1.46475
FRMD3 FERM domain containing 3 -1.46188
NEURL4 neuralized E3 ubiquitin protein ligase 4 -1.46144
MLEC malectin -1.45346
TPO thyroid peroxidase -1.45337
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -1.45309
DMRTC2 DMRT-like family C2 -1.44387
SYCE1 synaptonemal complex central element protein 1 -1.44267
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -1.42863
ADAMDEC1 ADAM-like, decysin 1 -1.42586
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 -1.42405
SPATA9 spermatogenesis associated 9 -1.41248
IQCF6 IQ motif containing F6 -1.40865
CPT1B carnitine palmitoyltransferase 1B (muscle) -1.39654
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -1.39643
IKZF3 IKAROS family zinc finger 3 (Aiolos) -1.39136
KDM8 lysine (K)-specific demethylase 8 -1.38101
SMYD5 SMYD family member 5 -1.37875
MSH5 mutS homolog 5 -1.37117
LPIN2 lipin 2 -1.36561
LDHAL6B lactate dehydrogenase A-like 6B -1.36398
LRRC34 leucine rich repeat containing 34 -1.35856
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 -1.35716
NDRG3 NDRG family member 3 -1.35139
KPNA1 karyopherin alpha 1 (importin alpha 5) -1.3452
SCUBE3 signal peptide, CUB domain, EGF-like 3 -1.34281
ARL2BP ADP-ribosylation factor-like 2 binding protein -1.33579
ACBD6 acyl-CoA binding domain containing 6 -1.33472
OTUD6A OTU deubiquitinase 6A -1.32648
MOCS3 molybdenum cofactor synthesis 3 -1.32195
PCBP3 poly(rC) binding protein 3 -1.32141
RBM18 RNA binding motif protein 18 -1.31146
ZNF329 zinc finger protein 329 -1.30844
DRD4 dopamine receptor D4 -1.30708
SLC22A14 solute carrier family 22, member 14 -1.30703
RET ret proto-oncogene -1.30363
STC2 stanniocalcin 2 -1.30159
R3HDM4 R3H domain containing 4 -1.30145
PANX1 pannexin 1 -1.29495
ZYX zyxin -1.29336
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit -1.29291
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -1.29085
CELA2A chymotrypsin-like elastase family, member 2A -1.28745
FAS Fas cell surface death receptor -1.28426
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) -1.28177
LMAN2L lectin, mannose-binding 2-like -1.27753
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -1.27056
AGER advanced glycosylation end product-specific receptor -1.26496
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 -1.26344
AHRR aryl-hydrocarbon receptor repressor -1.26256
CLDN6 claudin 6 -1.25928
CLDN22 claudin 22 -1.25819
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 -1.25602
ARX aristaless related homeobox -1.25542
PROKR2 prokineticin receptor 2 -1.25473
POU4F2 POU class 4 homeobox 2 -1.25181
SLITRK1 SLIT and NTRK-like family, member 1 -1.24812
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 -1.24566
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 -1.22164
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) -1.2206
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 -1.21369
TECTA tectorin alpha -1.21271
LRRC43 leucine rich repeat containing 43 -1.21255
WDR70 WD repeat domain 70 -1.2075
SAMD14 sterile alpha motif domain containing 14 -1.20725
CLCNKB chloride channel, voltage-sensitive Kb -1.20617
TAS2R60 taste receptor, type 2, member 60 -1.20393
MRPS18A mitochondrial ribosomal protein S18A -1.19803
DSG4 desmoglein 4 -1.19786
IGFBPL1 insulin-like growth factor binding protein-like 1 -1.19625
STRA6 stimulated by retinoic acid 6 -1.19543
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) -1.19271
NPY5R neuropeptide Y receptor Y5 -1.18884
MYO16 myosin XVI -1.18782
KLHL26 kelch-like family member 26 -1.1874
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -1.18231
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E -1.18022
LMX1A LIM homeobox transcription factor 1, alpha -1.173
GSK3A glycogen synthase kinase 3 alpha -1.17115
SYTL1 synaptotagmin-like 1 -1.17055
PVRL4 poliovirus receptor-related 4 -1.16934
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -1.16501
CABP7 calcium binding protein 7 -1.16132
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -1.1604
GDF2 growth differentiation factor 2 -1.1599
BMPR1A bone morphogenetic protein receptor, type IA -1.15977
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) -1.15696
ZNF746 zinc finger protein 746 -1.15518
GPR63 G protein-coupled receptor 63 -1.15489
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -1.1518
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -1.15118
MEP1A meprin A, alpha (PABA peptide hydrolase) -1.15095
OLIG2 oligodendrocyte lineage transcription factor 2 -1.14869
PHF19 PHD finger protein 19 -1.1474
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -1.14693
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 -1.14677
PIAS3 protein inhibitor of activated STAT, 3 -1.14469
SYTL3 synaptotagmin-like 3 -1.14209
FAM161A family with sequence similarity 161, member A -1.14101
MORC4 MORC family CW-type zinc finger 4 -1.13981
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime -1.13826
KLF12 Kruppel-like factor 12 -1.13817
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -1.13809
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -1.13598
RGS20 regulator of G-protein signaling 20 -1.13513
DYNLRB2 dynein, light chain, roadblock-type 2 -1.13197
GIMAP8 GTPase, IMAP family member 8 -1.12822
LOC102723475 putative uncharacterized protein LOC388820 -1.12725
CDCP1 CUB domain containing protein 1 -1.12419
GPR101 G protein-coupled receptor 101 -1.12341
FGF5 fibroblast growth factor 5 -1.12251
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -1.1208
CHKB choline kinase beta -1.1205
TRIM62 tripartite motif containing 62 -1.11998
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -1.11692
DCAF17 DDB1 and CUL4 associated factor 17 -1.11617
SEPHS2 selenophosphate synthetase 2 -1.11502
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 -1.1146
PQLC2 PQ loop repeat containing 2 -1.11459
PARD6G par-6 family cell polarity regulator gamma -1.11384
ACTL7A actin-like 7A -1.11098
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -1.10807
PTPRT protein tyrosine phosphatase, receptor type, T -1.10699
RTN4IP1 reticulon 4 interacting protein 1 -1.10529
GUCA1B guanylate cyclase activator 1B (retina) -1.1048
SH3BP4 SH3-domain binding protein 4 -1.10421
TMEM156 transmembrane protein 156 -1.10133
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) -1.10062
NTF3 neurotrophin 3 -1.09511
NGDN neuroguidin, EIF4E binding protein -1.09451
NYX nyctalopin -1.09219
RAPSN receptor-associated protein of the synapse -1.08756
ING1 inhibitor of growth family, member 1 -1.08603
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -1.0824
PNPLA5 patatin-like phospholipase domain containing 5 -1.07625
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 -1.06951
TOM1L2 target of myb1-like 2 (chicken) -1.06913
OLFM3 olfactomedin 3 -1.06432
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -1.06232
FBXO28 F-box protein 28 -1.05846
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -1.05742
LYPD1 LY6/PLAUR domain containing 1 -1.05665
ZC3H12C zinc finger CCCH-type containing 12C -1.05411
THAP4 THAP domain containing 4 -1.04995
COPE coatomer protein complex, subunit epsilon -1.04893
ALKBH8 alkB, alkylation repair homolog 8 (E. coli) -1.0467
LARP6 La ribonucleoprotein domain family, member 6 -1.04669
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -1.04611
PAX8 paired box 8 -1.04455
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -1.04409
ARHGAP23 Rho GTPase activating protein 23 -1.04275
KCNK9 potassium channel, two pore domain subfamily K, member 9 -1.04244
ANKRD10 ankyrin repeat domain 10 -1.04129
CTRB2 chymotrypsinogen B2 -1.04106
PSKH1 protein serine kinase H1 -1.0409
SUGP1 SURP and G patch domain containing 1 -1.03946
BRSK1 BR serine/threonine kinase 1 -1.03833
MAMDC4 MAM domain containing 4 -1.03743
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 -1.03674
RPTN repetin -1.03654
SEC14L5 SEC14-like 5 (S. cerevisiae) -1.03641
TRIM69 tripartite motif containing 69 -1.03607
HMG20A high mobility group 20A -1.03566
KRT1 keratin 1, type II -1.03429
PCDHGB3 protocadherin gamma subfamily B, 3 -1.03419
RAD51C RAD51 paralog C -1.03196
NPPA natriuretic peptide A -1.0285
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -1.02504
WNT9B wingless-type MMTV integration site family, member 9B -1.02323
CDK12 cyclin-dependent kinase 12 -1.0229
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -1.0205
GIMAP6 GTPase, IMAP family member 6 -1.01889
TMEM130 transmembrane protein 130 -1.01718
MYPN myopalladin -1.01696
GSC2 goosecoid homeobox 2 -1.01655
TRIB1 tribbles pseudokinase 1 -1.01504
STX1A syntaxin 1A (brain) -1.01375
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -1.0125
CLCN2 chloride channel, voltage-sensitive 2 -1.01232
CCKAR cholecystokinin A receptor -1.01171
TNS3 tensin 3 -1.01151
MBNL3 muscleblind-like splicing regulator 3 -1.01047
NOSTRIN nitric oxide synthase trafficking -1.00897
CSRNP3 cysteine-serine-rich nuclear protein 3 -1.00897
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 -1.0087
NPAS1 neuronal PAS domain protein 1 -1.00296
LSM10 LSM10, U7 small nuclear RNA associated -1.00122