EGFR_drugactivation_20_GDS2146 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2146
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Genes

600 genes differentially expressed following the EGFR_drugactivation_20_GDS2146 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
ZNF524 zinc finger protein 524 4.05955
BAIAP2L1 BAI1-associated protein 2-like 1 3.42098
SRP68 signal recognition particle 68kDa 3.39511
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 3.37491
FGF2 fibroblast growth factor 2 (basic) 3.32788
LYRM9 LYR motif containing 9 3.22854
EGR1 early growth response 1 3.17474
RUNX1 runt-related transcription factor 1 3.17276
SLK STE20-like kinase 3.15013
NME1 NME/NM23 nucleoside diphosphate kinase 1 3.08295
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 3.06641
SC5D sterol-C5-desaturase 2.97084
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.95776
COPG1 coatomer protein complex, subunit gamma 1 2.93436
PAK1IP1 PAK1 interacting protein 1 2.93363
LOXL2 lysyl oxidase-like 2 2.91841
EIF3B eukaryotic translation initiation factor 3, subunit B 2.86962
PKP1 plakophilin 1 2.85335
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 2.85086
FHL3 four and a half LIM domains 3 2.8275
TRMT61A tRNA methyltransferase 61A 2.81944
SIVA1 SIVA1, apoptosis-inducing factor 2.76824
ZNF180 zinc finger protein 180 2.76405
PGP phosphoglycolate phosphatase 2.73347
NEURL4 neuralized E3 ubiquitin protein ligase 4 2.72932
PRMT1 protein arginine methyltransferase 1 2.70931
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 2.63618
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.58955
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 2.55489
SFT2D1 SFT2 domain containing 1 2.53174
DHCR24 24-dehydrocholesterol reductase 2.51683
DUSP5 dual specificity phosphatase 5 2.50362
TNPO2 transportin 2 2.47421
SERTAD1 SERTA domain containing 1 2.47349
WNT2 wingless-type MMTV integration site family member 2 2.46281
DTYMK deoxythymidylate kinase (thymidylate kinase) 2.46034
RARS arginyl-tRNA synthetase 2.45942
SAR1A secretion associated, Ras related GTPase 1A 2.44579
EMG1 EMG1 N1-specific pseudouridine methyltransferase 2.43098
NFX1 nuclear transcription factor, X-box binding 1 2.43079
PYCR1 pyrroline-5-carboxylate reductase 1 2.42998
FAM102B family with sequence similarity 102, member B 2.40457
NCL nucleolin 2.40245
GSS glutathione synthetase 2.39759
CLIC1 chloride intracellular channel 1 2.39473
UBXN6 UBX domain protein 6 2.39236
UBQLN1 ubiquilin 1 2.38718
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 2.38531
SDC1 syndecan 1 2.36106
KCTD10 potassium channel tetramerization domain containing 10 2.35099
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 2.34524
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.33151
FDFT1 farnesyl-diphosphate farnesyltransferase 1 2.31703
NUP62 nucleoporin 62kDa 2.29928
NEK7 NIMA-related kinase 7 2.28769
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.287
B9D1 B9 protein domain 1 2.27413
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 2.26816
KIFC3 kinesin family member C3 2.26299
CDC42SE1 CDC42 small effector 1 2.26072
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.25433
MED17 mediator complex subunit 17 2.2481
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 2.24619
ABHD17A abhydrolase domain containing 17A 2.22307
HIGD1A HIG1 hypoxia inducible domain family, member 1A 2.20577
ETF1 eukaryotic translation termination factor 1 2.20198
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 2.19775
NOP2 NOP2 nucleolar protein 2.17632
RAB11A RAB11A, member RAS oncogene family 2.15376
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 2.15181
SEC11C SEC11 homolog C (S. cerevisiae) 2.15022
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.14546
IFRD1 interferon-related developmental regulator 1 2.14387
ERCC1 excision repair cross-complementation group 1 2.12024
WRB tryptophan rich basic protein 2.12014
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.11748
CCNYL1 cyclin Y-like 1 2.11265
ATF6 activating transcription factor 6 2.11108
WDR1 WD repeat domain 1 2.08986
ARL16 ADP-ribosylation factor-like 16 2.0847
MMD monocyte to macrophage differentiation-associated 2.08248
ACSL4 acyl-CoA synthetase long-chain family member 4 2.07871
QSOX2 quiescin Q6 sulfhydryl oxidase 2 2.06688
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.04705
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 2.03556
PITPNB phosphatidylinositol transfer protein, beta 2.03407
AIDA axin interactor, dorsalization associated 2.02051
BIN1 bridging integrator 1 2.00568
CREB3L2 cAMP responsive element binding protein 3-like 2 1.99568
OSBPL9 oxysterol binding protein-like 9 1.98834
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.988
MRPL49 mitochondrial ribosomal protein L49 1.98636
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 1.98475
VCAN versican 1.98096
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.96688
PDRG1 p53 and DNA-damage regulated 1 1.96028
KIFAP3 kinesin-associated protein 3 1.95171
METAP2 methionyl aminopeptidase 2 1.95122
TMEM39A transmembrane protein 39A 1.94953
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 1.9411
BRI3BP BRI3 binding protein 1.9406
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 1.93994
KLF6 Kruppel-like factor 6 1.9392
RABIF RAB interacting factor 1.93705
GFPT2 glutamine-fructose-6-phosphate transaminase 2 1.93048
MFSD12 major facilitator superfamily domain containing 12 1.90753
LTBP1 latent transforming growth factor beta binding protein 1 1.89675
UBA5 ubiquitin-like modifier activating enzyme 5 1.8949
STK24 serine/threonine kinase 24 1.89383
PRAF2 PRA1 domain family, member 2 1.88278
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.8806
FNTB farnesyltransferase, CAAX box, beta 1.87882
PRUNE2 prune homolog 2 (Drosophila) 1.87754
S100A16 S100 calcium binding protein A16 1.8772
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 1.86827
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 1.86475
RNF150 ring finger protein 150 1.85896
PBDC1 polysaccharide biosynthesis domain containing 1 1.85631
NINJ1 ninjurin 1 1.83769
TRAPPC6B trafficking protein particle complex 6B 1.83696
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.83378
GNG12 guanine nucleotide binding protein (G protein), gamma 12 1.83371
ELOVL6 ELOVL fatty acid elongase 6 1.83095
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 1.83078
ARL4C ADP-ribosylation factor-like 4C 1.82899
PLCD1 phospholipase C, delta 1 1.82486
MAP6 microtubule-associated protein 6 1.82469
MRPL17 mitochondrial ribosomal protein L17 1.81773
TRMT6 tRNA methyltransferase 6 1.81625
MTAP methylthioadenosine phosphorylase 1.80994
FBXL14 F-box and leucine-rich repeat protein 14 1.80771
RIPK3 receptor-interacting serine-threonine kinase 3 1.80596
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.79449
SMIM3 small integral membrane protein 3 1.7939
EIF6 eukaryotic translation initiation factor 6 1.78034
AXL AXL receptor tyrosine kinase 1.77485
MSMO1 methylsterol monooxygenase 1 1.76195
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 1.75605
PITPNA phosphatidylinositol transfer protein, alpha 1.75419
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.75358
CERK ceramide kinase 1.75332
PVR poliovirus receptor 1.75049
NQO1 NAD(P)H dehydrogenase, quinone 1 1.74344
REEP3 receptor accessory protein 3 1.74292
ETV5 ets variant 5 1.73676
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.73519
RAB2A RAB2A, member RAS oncogene family 1.73132
LGALS3 lectin, galactoside-binding, soluble, 3 1.73082
IRF2BP2 interferon regulatory factor 2 binding protein 2 1.72614
TGIF1 TGFB-induced factor homeobox 1 1.72469
PIAS2 protein inhibitor of activated STAT, 2 1.71793
AHCY adenosylhomocysteinase 1.71564
FASN fatty acid synthase 1.71333
MTFR1 mitochondrial fission regulator 1 1.71116
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.70036
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 1.70004
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 1.68895
SEC13 SEC13 homolog (S. cerevisiae) 1.68229
TTC19 tetratricopeptide repeat domain 19 1.67519
TRIM8 tripartite motif containing 8 1.67183
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 1.66698
IQGAP1 IQ motif containing GTPase activating protein 1 1.66294
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.65753
ARG1 arginase 1 1.64384
TMEM208 transmembrane protein 208 1.64368
DPY19L3 dpy-19-like 3 (C. elegans) 1.64299
NRN1 neuritin 1 1.64069
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.64018
USP28 ubiquitin specific peptidase 28 1.63924
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.63158
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.62929
ILK integrin-linked kinase 1.62792
MYBBP1A MYB binding protein (P160) 1a 1.62349
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.61746
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 1.61026
APOOL apolipoprotein O-like 1.60843
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 1.60516
POMP proteasome maturation protein 1.60387
UBTD1 ubiquitin domain containing 1 1.60242
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 1.5991
LUC7L LUC7-like (S. cerevisiae) 1.58891
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 1.5887
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.58565
ANO1 anoctamin 1, calcium activated chloride channel 1.58308
GAS7 growth arrest-specific 7 1.57948
MYOF myoferlin 1.5788
HN1 hematological and neurological expressed 1 1.57851
TMX1 thioredoxin-related transmembrane protein 1 1.5768
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.5485
SART1 squamous cell carcinoma antigen recognized by T cells 1.54172
CCT8 chaperonin containing TCP1, subunit 8 (theta) 1.54172
AHCTF1 AT hook containing transcription factor 1 1.54023
FKBP11 FK506 binding protein 11, 19 kDa 1.53136
CLIP2 CAP-GLY domain containing linker protein 2 1.52983
RHBDD2 rhomboid domain containing 2 1.5243
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 1.51946
PXDN peroxidasin 1.51316
ACLY ATP citrate lyase 1.50807
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.50786
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 1.50194
RHOQ ras homolog family member Q 1.50058
UXS1 UDP-glucuronate decarboxylase 1 1.49738
RECQL RecQ helicase-like 1.49608
SSR1 signal sequence receptor, alpha 1.49552
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 1.4944
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 1.48917
TSPAN2 tetraspanin 2 1.48714
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.48399
TMEM214 transmembrane protein 214 1.48081
MMP16 matrix metallopeptidase 16 (membrane-inserted) 1.47937
CUL1 cullin 1 1.47234
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 1.47142
SMAGP small cell adhesion glycoprotein 1.46763
BDKRB2 bradykinin receptor B2 1.46694
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 1.46649
TPBG trophoblast glycoprotein 1.46536
PFKP phosphofructokinase, platelet 1.4629
TEC tec protein tyrosine kinase 1.46163
HNRNPL heterogeneous nuclear ribonucleoprotein L 1.45915
MUM1L1 melanoma associated antigen (mutated) 1-like 1 1.45856
ZBTB44 zinc finger and BTB domain containing 44 1.4575
FJX1 four jointed box 1 (Drosophila) 1.45527
BHLHE40 basic helix-loop-helix family, member e40 1.45395
MEF2A myocyte enhancer factor 2A 1.44775
WDR43 WD repeat domain 43 1.44571
FOSL1 FOS-like antigen 1 1.43588
PDCD6 programmed cell death 6 1.43583
GAK cyclin G associated kinase 1.43254
FTSJ3 FtsJ homolog 3 (E. coli) 1.42883
RTKN rhotekin 1.42744
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 1.42619
SPAG9 sperm associated antigen 9 1.42522
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1.41458
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.41446
XBP1 X-box binding protein 1 1.41436
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.41407
TSPAN8 tetraspanin 8 1.40991
BAIAP2 BAI1-associated protein 2 1.40961
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.40836
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 1.40668
MCL1 myeloid cell leukemia 1 1.40404
ARL4A ADP-ribosylation factor-like 4A 1.40383
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 1.40272
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 1.39518
HTT huntingtin 1.39364
NPTX1 neuronal pentraxin I 1.38454
YIPF5 Yip1 domain family, member 5 1.38384
S100A4 S100 calcium binding protein A4 1.38221
PDIA3 protein disulfide isomerase family A, member 3 1.38004
PRMT5 protein arginine methyltransferase 5 1.37885
ACAT2 acetyl-CoA acetyltransferase 2 1.37521
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.37343
TCP1 t-complex 1 1.37212
CNRIP1 cannabinoid receptor interacting protein 1 1.36645
NAP1L1 nucleosome assembly protein 1-like 1 1.36617
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.36385
PLEC plectin 1.36286
EMB embigin 1.36143
KCTD15 potassium channel tetramerization domain containing 15 1.35621
CAPG capping protein (actin filament), gelsolin-like 1.35566
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 1.35158
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.35103
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.35088
LMNA lamin A/C 1.34993
REXO2 RNA exonuclease 2 1.34806
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.33846
RAB11FIP5 RAB11 family interacting protein 5 (class I) 1.33496
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.33397
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.33089
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 1.3292
CCND1 cyclin D1 1.32851
FDPS farnesyl diphosphate synthase 1.32819
GXYLT1 glucoside xylosyltransferase 1 1.32425
ABHD2 abhydrolase domain containing 2 1.31668
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.31554
GSTCD glutathione S-transferase, C-terminal domain containing 1.31523
SURF4 surfeit 4 1.31474
NID2 nidogen 2 (osteonidogen) 1.31459
MRPL43 mitochondrial ribosomal protein L43 1.3111
SMAD5 SMAD family member 5 1.31098
ATXN10 ataxin 10 1.31044
PCNP PEST proteolytic signal containing nuclear protein 1.30928
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 1.30878
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 1.30817
ADCK4 aarF domain containing kinase 4 1.3077
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 1.30279
TRAK2 trafficking protein, kinesin binding 2 1.29804
EBNA1BP2 EBNA1 binding protein 2 1.29359
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.29247
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 1.29179
MGST2 microsomal glutathione S-transferase 2 1.29143
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 1.2891
REEP5 receptor accessory protein 5 1.28859
JTB jumping translocation breakpoint 1.28814
MAPK6 mitogen-activated protein kinase 6 1.28534
DPY19L1 dpy-19-like 1 (C. elegans) 1.28314
TUBA4A tubulin, alpha 4a 1.2791
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 1.27816
MRPL39 mitochondrial ribosomal protein L39 1.27272
HN1L hematological and neurological expressed 1-like 1.2704

decreased expression

Symbol Name Standardized Value
FLCN folliculin -4.35204
LMBRD1 LMBR1 domain containing 1 -4.26214
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -3.68873
TBC1D31 TBC1 domain family, member 31 -3.64005
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -3.55092
GSTA5 glutathione S-transferase alpha 5 -3.52755
TRIM5 tripartite motif containing 5 -3.45374
NXT1 nuclear transport factor 2-like export factor 1 -3.3356
SELENBP1 selenium binding protein 1 -3.26406
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) -3.25939
NPR2 natriuretic peptide receptor 2 -3.11219
RNF13 ring finger protein 13 -3.0815
CP ceruloplasmin (ferroxidase) -3.07812
ANKRD12 ankyrin repeat domain 12 -3.06813
EMC2 ER membrane protein complex subunit 2 -2.94097
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -2.92727
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -2.92106
TRAPPC12 trafficking protein particle complex 12 -2.91093
CTSH cathepsin H -2.86344
GDI1 GDP dissociation inhibitor 1 -2.82915
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -2.81669
TBC1D19 TBC1 domain family, member 19 -2.78213
PDLIM2 PDZ and LIM domain 2 (mystique) -2.74306
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -2.7353
GULP1 GULP, engulfment adaptor PTB domain containing 1 -2.73315
CLK1 CDC-like kinase 1 -2.71606
PTDSS2 phosphatidylserine synthase 2 -2.70145
NEO1 neogenin 1 -2.68547
DHRS3 dehydrogenase/reductase (SDR family) member 3 -2.67306
CREBL2 cAMP responsive element binding protein-like 2 -2.65641
METRNL meteorin, glial cell differentiation regulator-like -2.60921
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -2.5859
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.58387
AAMDC adipogenesis associated, Mth938 domain containing -2.58115
CEP70 centrosomal protein 70kDa -2.57672
FZD1 frizzled class receptor 1 -2.57133
SUN2 Sad1 and UNC84 domain containing 2 -2.54203
FAM134A family with sequence similarity 134, member A -2.49252
TRIM32 tripartite motif containing 32 -2.46821
OXR1 oxidation resistance 1 -2.4644
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -2.45447
MGMT O-6-methylguanine-DNA methyltransferase -2.45021
ADD3 adducin 3 (gamma) -2.44831
STRADB STE20-related kinase adaptor beta -2.43923
KCTD9 potassium channel tetramerization domain containing 9 -2.42226
VSNL1 visinin-like 1 -2.41572
MIER3 mesoderm induction early response 1, family member 3 -2.38546
LAMP2 lysosomal-associated membrane protein 2 -2.38417
TMEM9B TMEM9 domain family, member B -2.35904
ISCU iron-sulfur cluster assembly enzyme -2.35285
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.34854
POC5 POC5 centriolar protein -2.34682
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 -2.34329
DTWD1 DTW domain containing 1 -2.32328
DDR2 discoidin domain receptor tyrosine kinase 2 -2.31589
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -2.31325
RAB11FIP1 RAB11 family interacting protein 1 (class I) -2.30678
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 -2.30571
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -2.30365
HELB helicase (DNA) B -2.30111
SDPR serum deprivation response -2.29617
WIZ widely interspaced zinc finger motifs -2.29378
ICAM1 intercellular adhesion molecule 1 -2.27645
GZF1 GDNF-inducible zinc finger protein 1 -2.27518
ZHX1 zinc fingers and homeoboxes 1 -2.26648
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -2.2644
CD83 CD83 molecule -2.2581
KLF11 Kruppel-like factor 11 -2.254
HS1BP3 HCLS1 binding protein 3 -2.2267
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -2.21822
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.21358
HEXB hexosaminidase B (beta polypeptide) -2.20798
XPA xeroderma pigmentosum, complementation group A -2.19749
SURF1 surfeit 1 -2.1923
INPP5K inositol polyphosphate-5-phosphatase K -2.19042
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -2.18612
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -2.18588
ZNF148 zinc finger protein 148 -2.18499
TMEM203 transmembrane protein 203 -2.17519
AKAP7 A kinase (PRKA) anchor protein 7 -2.16268
SH2D4A SH2 domain containing 4A -2.16167
ZNF346 zinc finger protein 346 -2.14017
FAM180A family with sequence similarity 180, member A -2.13071
GIMAP6 GTPase, IMAP family member 6 -2.11338
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -2.11216
ZC3H6 zinc finger CCCH-type containing 6 -2.10415
TNIP1 TNFAIP3 interacting protein 1 -2.09512
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -2.0937
RCAN2 regulator of calcineurin 2 -2.07942
BMP4 bone morphogenetic protein 4 -2.07681
RGMA repulsive guidance molecule family member a -2.07655
IDUA iduronidase, alpha-L- -2.07499
CDO1 cysteine dioxygenase type 1 -2.07212
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -2.06734
TLE2 transducin-like enhancer of split 2 -2.06263
PROS1 protein S (alpha) -2.05699
SPTA1 spectrin, alpha, erythrocytic 1 -2.05142
OGN osteoglycin -2.03356
LPL lipoprotein lipase -2.03264
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -2.02044
CLTB clathrin, light chain B -2.01515
TTC3 tetratricopeptide repeat domain 3 -2.01137
LIMK2 LIM domain kinase 2 -2.0093
SH3TC2 SH3 domain and tetratricopeptide repeats 2 -2.00886
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -2.00548
CYHR1 cysteine/histidine-rich 1 -2.00316
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 -2.00191
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -1.9969
ADAMTSL4 ADAMTS-like 4 -1.99376
SNUPN snurportin 1 -1.99159
PLXNB2 plexin B2 -1.98412
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -1.97831
CDADC1 cytidine and dCMP deaminase domain containing 1 -1.96791
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -1.96081
RFT1 RFT1 homolog (S. cerevisiae) -1.95136
RAI14 retinoic acid induced 14 -1.94544
TNC tenascin C -1.94187
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.94143
ZFAND6 zinc finger, AN1-type domain 6 -1.9402
TNRC6C trinucleotide repeat containing 6C -1.93811
GRTP1 growth hormone regulated TBC protein 1 -1.92884
PHPT1 phosphohistidine phosphatase 1 -1.9274
PER2 period circadian clock 2 -1.92084
LYRM5 LYR motif containing 5 -1.91142
DMPK dystrophia myotonica-protein kinase -1.90672
LPAR1 lysophosphatidic acid receptor 1 -1.90281
ANXA3 annexin A3 -1.90104
AQP9 aquaporin 9 -1.88777
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -1.88602
EXOC2 exocyst complex component 2 -1.88469
NGB neuroglobin -1.87791
KLHL24 kelch-like family member 24 -1.87735
PPP1R21 protein phosphatase 1, regulatory subunit 21 -1.87442
SDC2 syndecan 2 -1.85931
GRN granulin -1.85871
ABHD17C abhydrolase domain containing 17C -1.85562
TXNDC15 thioredoxin domain containing 15 -1.84456
OLFML2A olfactomedin-like 2A -1.84249
GADD45B growth arrest and DNA-damage-inducible, beta -1.84229
TWSG1 twisted gastrulation BMP signaling modulator 1 -1.84079
LAMB2 laminin, beta 2 (laminin S) -1.82884
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -1.82665
TRAFD1 TRAF-type zinc finger domain containing 1 -1.81978
CDC73 cell division cycle 73 -1.81963
TSPAN6 tetraspanin 6 -1.81221
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 -1.80484
TRAPPC6A trafficking protein particle complex 6A -1.80453
SPATS2L spermatogenesis associated, serine-rich 2-like -1.79765
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 -1.79524
SNIP1 Smad nuclear interacting protein 1 -1.78719
NTNG1 netrin G1 -1.77877
ATAD1 ATPase family, AAA domain containing 1 -1.77568
TRIM24 tripartite motif containing 24 -1.77048
ATG3 autophagy related 3 -1.77027
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -1.75976
ERCC6L2 excision repair cross-complementation group 6-like 2 -1.7581
NFU1 NFU1 iron-sulfur cluster scaffold -1.74963
LZIC leucine zipper and CTNNBIP1 domain containing -1.74721
KIZ kizuna centrosomal protein -1.74657
HIST2H4A histone cluster 2, H4a -1.74385
BBS7 Bardet-Biedl syndrome 7 -1.73839
FGF13 fibroblast growth factor 13 -1.73486
AFAP1L2 actin filament associated protein 1-like 2 -1.72335
ITM2B integral membrane protein 2B -1.72289
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 -1.71975
CDK19 cyclin-dependent kinase 19 -1.7099
CALCOCO1 calcium binding and coiled-coil domain 1 -1.70906
EDRF1 erythroid differentiation regulatory factor 1 -1.70759
MDH1 malate dehydrogenase 1, NAD (soluble) -1.70412
FAM171B family with sequence similarity 171, member B -1.70073
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -1.69326
ACOT2 acyl-CoA thioesterase 2 -1.69259
ING2 inhibitor of growth family, member 2 -1.69229
ZNF202 zinc finger protein 202 -1.6837
AGA aspartylglucosaminidase -1.68292
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -1.67944
PHOSPHO2 phosphatase, orphan 2 -1.67698
AMOTL2 angiomotin like 2 -1.67223
ATOH8 atonal homolog 8 (Drosophila) -1.66527
ZNF521 zinc finger protein 521 -1.663
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.66288
KANSL3 KAT8 regulatory NSL complex subunit 3 -1.65863
MED12 mediator complex subunit 12 -1.6577
CPQ carboxypeptidase Q -1.65625
ST5 suppression of tumorigenicity 5 -1.656
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -1.65507
STMN1 stathmin 1 -1.64936
UROD uroporphyrinogen decarboxylase -1.64499
PON2 paraoxonase 2 -1.64495
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -1.64288
FAM122A family with sequence similarity 122A -1.63988
HMOX1 heme oxygenase 1 -1.63985
EIF5A2 eukaryotic translation initiation factor 5A2 -1.63475
ZMIZ2 zinc finger, MIZ-type containing 2 -1.63263
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -1.6316
ZNFX1 zinc finger, NFX1-type containing 1 -1.62954
PYGB phosphorylase, glycogen; brain -1.62506
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin -1.61667
BEND5 BEN domain containing 5 -1.61238
OXCT1 3-oxoacid CoA transferase 1 -1.60898
FMO5 flavin containing monooxygenase 5 -1.60667
LYSMD4 LysM, putative peptidoglycan-binding, domain containing 4 -1.60556
DGAT2 diacylglycerol O-acyltransferase 2 -1.6017
LMF2 lipase maturation factor 2 -1.59585
NAP1L3 nucleosome assembly protein 1-like 3 -1.59473
MYNN myoneurin -1.59374
SPATA24 spermatogenesis associated 24 -1.59182
CKS2 CDC28 protein kinase regulatory subunit 2 -1.58863
FMO3 flavin containing monooxygenase 3 -1.5878
ABHD14A abhydrolase domain containing 14A -1.5871
EHBP1 EH domain binding protein 1 -1.58674
GUSB glucuronidase, beta -1.57758
TCN2 transcobalamin II -1.57607
MATR3 matrin 3 -1.57309
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -1.57307
RPP25L ribonuclease P/MRP 25kDa subunit-like -1.573
TESK1 testis-specific kinase 1 -1.57218
PBX3 pre-B-cell leukemia homeobox 3 -1.57114
ZFP36L1 ZFP36 ring finger protein-like 1 -1.56994
CCNG2 cyclin G2 -1.55393
GNB5 guanine nucleotide binding protein (G protein), beta 5 -1.5468
SORD sorbitol dehydrogenase -1.54559
RNF122 ring finger protein 122 -1.54348
TSEN54 TSEN54 tRNA splicing endonuclease subunit -1.54283
HMG20A high mobility group 20A -1.54203
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -1.54074
CCDC28A coiled-coil domain containing 28A -1.54053
UNC119 unc-119 homolog (C. elegans) -1.53576
METTL20 methyltransferase like 20 -1.53162
USP21 ubiquitin specific peptidase 21 -1.52948
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -1.51097
TTC30B tetratricopeptide repeat domain 30B -1.51012
IL17RE interleukin 17 receptor E -1.50538
SDHAF3 succinate dehydrogenase complex assembly factor 3 -1.5031
NADK2 NAD kinase 2, mitochondrial -1.50105
DCAF7 DDB1 and CUL4 associated factor 7 -1.49642
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -1.4933
NPAT nuclear protein, ataxia-telangiectasia locus -1.49235
PCOLCE procollagen C-endopeptidase enhancer -1.49002
SLC48A1 solute carrier family 48 (heme transporter), member 1 -1.48927
KLHL7 kelch-like family member 7 -1.48788
KLF5 Kruppel-like factor 5 (intestinal) -1.48451
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -1.48377
LNX2 ligand of numb-protein X 2 -1.47551
KANK4 KN motif and ankyrin repeat domains 4 -1.475
MED23 mediator complex subunit 23 -1.47495
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -1.47419
RNF111 ring finger protein 111 -1.4644
CLIC3 chloride intracellular channel 3 -1.46228
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -1.46096
RAB33A RAB33A, member RAS oncogene family -1.458
FAT4 FAT atypical cadherin 4 -1.45599
RNF146 ring finger protein 146 -1.45407
CLDN11 claudin 11 -1.45333
GTPBP2 GTP binding protein 2 -1.45251
RAB18 RAB18, member RAS oncogene family -1.45179
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.44937
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -1.44859
C1QTNF5 C1q and tumor necrosis factor related protein 5 -1.43959
RBFA ribosome binding factor A (putative) -1.43918
MORC4 MORC family CW-type zinc finger 4 -1.43881
COQ10A coenzyme Q10 homolog A (S. cerevisiae) -1.43638
PGRMC1 progesterone receptor membrane component 1 -1.43435
POPDC3 popeye domain containing 3 -1.43429
ZNF365 zinc finger protein 365 -1.43166
BRPF1 bromodomain and PHD finger containing, 1 -1.43052
IFI30 interferon, gamma-inducible protein 30 -1.42889
IRF9 interferon regulatory factor 9 -1.42804
ZNF423 zinc finger protein 423 -1.42673
LAMB3 laminin, beta 3 -1.42402
CKAP2 cytoskeleton associated protein 2 -1.42348
RABGAP1L RAB GTPase activating protein 1-like -1.42265
CCDC80 coiled-coil domain containing 80 -1.41714
GPC1 glypican 1 -1.41662
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -1.40821
IPO13 importin 13 -1.40776
HSPA2 heat shock 70kDa protein 2 -1.40641
MXRA8 matrix-remodelling associated 8 -1.40548
PAXBP1 PAX3 and PAX7 binding protein 1 -1.40229
ARHGAP18 Rho GTPase activating protein 18 -1.39679
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 -1.39529
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 -1.39472
SCO1 SCO1 cytochrome c oxidase assembly protein -1.39322
IGBP1 immunoglobulin (CD79A) binding protein 1 -1.39299
PNISR PNN-interacting serine/arginine-rich protein -1.38208
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -1.38
SCPEP1 serine carboxypeptidase 1 -1.37636
OSTM1 osteopetrosis associated transmembrane protein 1 -1.37422
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 -1.36808
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -1.36799
INTS4 integrator complex subunit 4 -1.36679
ZSWIM6 zinc finger, SWIM-type containing 6 -1.36664
ACOX1 acyl-CoA oxidase 1, palmitoyl -1.3662
RTFDC1 replication termination factor 2 domain containing 1 -1.36196
MYD88 myeloid differentiation primary response 88 -1.3613
CHD3 chromodomain helicase DNA binding protein 3 -1.35729
FLRT3 fibronectin leucine rich transmembrane protein 3 -1.35351
MCOLN1 mucolipin 1 -1.35032
FAM173A family with sequence similarity 173, member A -1.34916
HMMR hyaluronan-mediated motility receptor (RHAMM) -1.34639