Duchenne muscular dystrophy (DMD)_Muscle - Striated (Skeletal) (MMHCC)_GSE1025 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1025
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Genes

600 genes differentially expressed during Duchenne muscular dystrophy (DMD)_Muscle - Striated (Skeletal) (MMHCC)_GSE1025 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ACOT9 acyl-CoA thioesterase 9 3.3075
SCARB2 scavenger receptor class B, member 2 3.03976
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 3.01149
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 2.86384
NAGK N-acetylglucosamine kinase 2.81535
TTC17 tetratricopeptide repeat domain 17 2.79583
REEP5 receptor accessory protein 5 2.72258
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 2.71261
SDCBP syndecan binding protein (syntenin) 2.6919
AKIRIN2 akirin 2 2.65231
MZT2A mitotic spindle organizing protein 2A 2.63478
GADD45A growth arrest and DNA-damage-inducible, alpha 2.5877
CYFIP1 cytoplasmic FMR1 interacting protein 1 2.58325
RPL7 ribosomal protein L7 2.53909
CCDC94 coiled-coil domain containing 94 2.48921
TFDP1 transcription factor Dp-1 2.48724
GBA glucosidase, beta, acid 2.47945
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.46035
USP3 ubiquitin specific peptidase 3 2.42767
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2.41195
FBXW11 F-box and WD repeat domain containing 11 2.40673
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.3813
SNX5 sorting nexin 5 2.37054
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 2.36759
THBD thrombomodulin 2.32583
MPP1 membrane protein, palmitoylated 1, 55kDa 2.32234
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 2.31596
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 2.31422
DSCR3 Down syndrome critical region 3 2.28032
TMEM246 transmembrane protein 246 2.27946
BAK1 BCL2-antagonist/killer 1 2.27387
CD63 CD63 molecule 2.26862
TMEM176B transmembrane protein 176B 2.26216
GTPBP4 GTP binding protein 4 2.26098
FOS FBJ murine osteosarcoma viral oncogene homolog 2.25786
VTA1 vesicle (multivesicular body) trafficking 1 2.25722
XBP1 X-box binding protein 1 2.24781
DIO2 deiodinase, iodothyronine, type II 2.24111
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2.23454
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 2.22907
EBP emopamil binding protein (sterol isomerase) 2.21041
SNX17 sorting nexin 17 2.19464
IPO8 importin 8 2.19357
NET1 neuroepithelial cell transforming 1 2.19194
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 2.18187
PLIN2 perilipin 2 2.18127
ELAVL1 ELAV like RNA binding protein 1 2.17135
HAUS8 HAUS augmin-like complex, subunit 8 2.16547
IER2 immediate early response 2 2.16344
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 2.15908
POMP proteasome maturation protein 2.1571
THRSP thyroid hormone responsive 2.14831
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 2.13893
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.13236
WTAP Wilms tumor 1 associated protein 2.12857
PCBP1 poly(rC) binding protein 1 2.12559
RRAD Ras-related associated with diabetes 2.11998
EPC1 enhancer of polycomb homolog 1 (Drosophila) 2.11272
CNPY2 canopy FGF signaling regulator 2 2.11062
IPO11 importin 11 2.10434
EXOC8 exocyst complex component 8 2.09462
STAT1 signal transducer and activator of transcription 1, 91kDa 2.09293
IRGM immunity-related GTPase family, M 2.08703
NOP58 NOP58 ribonucleoprotein 2.08393
TMEM62 transmembrane protein 62 2.08231
RASA1 RAS p21 protein activator (GTPase activating protein) 1 2.07728
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 2.05958
MDP1 magnesium-dependent phosphatase 1 2.05881
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.05041
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2.04688
MYOD1 myogenic differentiation 1 2.03556
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.03077
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.03024
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.02627
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 2.02602
MYL4 myosin, light chain 4, alkali; atrial, embryonic 2.02256
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 2.02112
FAM49B family with sequence similarity 49, member B 2.00287
LGMN legumain 2.00125
CAPRIN2 caprin family member 2 1.99892
SFR1 SWI5-dependent recombination repair 1 1.99686
RBM18 RNA binding motif protein 18 1.99273
OSTF1 osteoclast stimulating factor 1 1.99213
CLTC clathrin, heavy chain (Hc) 1.9791
CTSV cathepsin V 1.97558
RNH1 ribonuclease/angiogenin inhibitor 1 1.97347
TPD52L2 tumor protein D52-like 2 1.97077
TPD52 tumor protein D52 1.96869
TUBA1B tubulin, alpha 1b 1.9672
ORC4 origin recognition complex, subunit 4 1.96498
TADA1 transcriptional adaptor 1 1.96454
METTL5 methyltransferase like 5 1.96371
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 1.96318
AIM1 absent in melanoma 1 1.95855
INPP5K inositol polyphosphate-5-phosphatase K 1.9513
FMO5 flavin containing monooxygenase 5 1.95074
H2AFY H2A histone family, member Y 1.94554
OCIAD1 OCIA domain containing 1 1.94482
PER1 period circadian clock 1 1.93791
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.93733
MAP2K3 mitogen-activated protein kinase kinase 3 1.93701
RAE1 ribonucleic acid export 1 1.93633
KLF6 Kruppel-like factor 6 1.93527
KDM3A lysine (K)-specific demethylase 3A 1.93526
ACTG1 actin gamma 1 1.93017
USP8 ubiquitin specific peptidase 8 1.92046
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.915
ARL5A ADP-ribosylation factor-like 5A 1.91347
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.91317
TEX30 testis expressed 30 1.9102
WDR26 WD repeat domain 26 1.90591
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 1.90505
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.90497
CDK8 cyclin-dependent kinase 8 1.90219
ROGDI rogdi homolog (Drosophila) 1.89851
FKBP1A FK506 binding protein 1A, 12kDa 1.89513
EMP1 epithelial membrane protein 1 1.87481
KLF10 Kruppel-like factor 10 1.86898
ITM2B integral membrane protein 2B 1.86806
HSPA8 heat shock 70kDa protein 8 1.86796
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 1.86662
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 1.86652
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 1.86464
SHMT1 serine hydroxymethyltransferase 1 (soluble) 1.86345
PON3 paraoxonase 3 1.86174
TCTA T-cell leukemia translocation altered 1.8615
GAS8 growth arrest-specific 8 1.85913
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.85307
OSBPL11 oxysterol binding protein-like 11 1.84729
FBXO9 F-box protein 9 1.84694
BCL10 B-cell CLL/lymphoma 10 1.83772
C9ORF85 chromosome 9 open reading frame 85 1.83582
SYK spleen tyrosine kinase 1.83382
CD302 CD302 molecule 1.8279
RAPSN receptor-associated protein of the synapse 1.81833
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 1.8161
MAPK6 mitogen-activated protein kinase 6 1.81468
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.81431
CPNE3 copine III 1.81362
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.81142
LITAF lipopolysaccharide-induced TNF factor 1.80796
CSTB cystatin B (stefin B) 1.79231
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.78985
ZFP36L2 ZFP36 ring finger protein-like 2 1.78435
MEF2D myocyte enhancer factor 2D 1.78365
CHRD chordin 1.77643
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.77475
PRPF38B pre-mRNA processing factor 38B 1.76611
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.75795
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.75563
MRPL52 mitochondrial ribosomal protein L52 1.75281
BCL3 B-cell CLL/lymphoma 3 1.74961
FGF11 fibroblast growth factor 11 1.74853
NFIL3 nuclear factor, interleukin 3 regulated 1.74846
ADAM9 ADAM metallopeptidase domain 9 1.74821
CD2 CD2 molecule 1.74696
ANXA4 annexin A4 1.74481
KLC4 kinesin light chain 4 1.74391
LGALS1 lectin, galactoside-binding, soluble, 1 1.74257
AEBP1 AE binding protein 1 1.74233
RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 1.73608
C15ORF39 chromosome 15 open reading frame 39 1.73581
ZSWIM1 zinc finger, SWIM-type containing 1 1.73493
AP3M1 adaptor-related protein complex 3, mu 1 subunit 1.73451
QSOX1 quiescin Q6 sulfhydryl oxidase 1 1.72981
IST1 increased sodium tolerance 1 homolog (yeast) 1.72955
CBX1 chromobox homolog 1 1.72558
NOP16 NOP16 nucleolar protein 1.72229
INPPL1 inositol polyphosphate phosphatase-like 1 1.72052
TM9SF2 transmembrane 9 superfamily member 2 1.71979
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.71327
RBMS1 RNA binding motif, single stranded interacting protein 1 1.71003
LIMS1 LIM and senescent cell antigen-like domains 1 1.70768
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1.70447
USP34 ubiquitin specific peptidase 34 1.70385
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.69354
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.68732
SNX3 sorting nexin 3 1.68454
IFT27 intraflagellar transport 27 1.68326
ZNF777 zinc finger protein 777 1.68037
CD14 CD14 molecule 1.67918
SERP1 stress-associated endoplasmic reticulum protein 1 1.67669
TSPO translocator protein (18kDa) 1.67512
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 1.67396
PAPOLA poly(A) polymerase alpha 1.67326
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 1.67281
LMNB1 lamin B1 1.67225
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 1.67118
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.67025
SHISA5 shisa family member 5 1.66939
TMEM43 transmembrane protein 43 1.66889
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.66588
SH3BP2 SH3-domain binding protein 2 1.66511
TMED9 transmembrane emp24 protein transport domain containing 9 1.66384
MORF4L1 mortality factor 4 like 1 1.66188
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.66036
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.65928
ACAD9 acyl-CoA dehydrogenase family, member 9 1.65895
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.6583
NEURL3 neuralized E3 ubiquitin protein ligase 3 1.65814
TCP1 t-complex 1 1.65687
STRN3 striatin, calmodulin binding protein 3 1.65012
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.64798
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.64721
POLR1E polymerase (RNA) I polypeptide E, 53kDa 1.64664
ARID1A AT rich interactive domain 1A (SWI-like) 1.64466
TXNDC9 thioredoxin domain containing 9 1.64442
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.64339
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.64247
FAM192A family with sequence similarity 192, member A 1.64137
GOLGA7 golgin A7 1.64083
NPC2 Niemann-Pick disease, type C2 1.63935
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 1.63894
C1QC complement component 1, q subcomponent, C chain 1.63566
AGFG1 ArfGAP with FG repeats 1 1.63519
IL4R interleukin 4 receptor 1.63089
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 1.63
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.62747
MAPK3 mitogen-activated protein kinase 3 1.62728
G6PD glucose-6-phosphate dehydrogenase 1.62569
LAMP2 lysosomal-associated membrane protein 2 1.62279
FOXK2 forkhead box K2 1.62256
SSR1 signal sequence receptor, alpha 1.61842
DDB1 damage-specific DNA binding protein 1, 127kDa 1.61737
ERRFI1 ERBB receptor feedback inhibitor 1 1.61637
ARID3B AT rich interactive domain 3B (BRIGHT-like) 1.61307
NCOA1 nuclear receptor coactivator 1 1.6123
NEK6 NIMA-related kinase 6 1.61195
JUNB jun B proto-oncogene 1.60688
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 1.60418
SEPT9 septin 9 1.60083
HDAC2 histone deacetylase 2 1.60057
CORO1A coronin, actin binding protein, 1A 1.59687
CCAR1 cell division cycle and apoptosis regulator 1 1.59618
TBC1D21 TBC1 domain family, member 21 1.59504
USO1 USO1 vesicle transport factor 1.59155
LENG9 leukocyte receptor cluster (LRC) member 9 1.5913
LIG3 ligase III, DNA, ATP-dependent 1.58974
RERE arginine-glutamic acid dipeptide (RE) repeats 1.5865
TUBA1A tubulin, alpha 1a 1.58313
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.57928
FN1 fibronectin 1 1.57674
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 1.57541
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.57044
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.56983
TUBB6 tubulin, beta 6 class V 1.56807
SF3A1 splicing factor 3a, subunit 1, 120kDa 1.5671
MORF4L2 mortality factor 4 like 2 1.56643
EIF3D eukaryotic translation initiation factor 3, subunit D 1.56294
CDADC1 cytidine and dCMP deaminase domain containing 1 1.56239
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.56195
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 1.55955
NTHL1 nth endonuclease III-like 1 (E. coli) 1.55262
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 1.55217
CCL13 chemokine (C-C motif) ligand 13 1.54473
CXCL6 chemokine (C-X-C motif) ligand 6 1.54395
XPO7 exportin 7 1.54369
TULP3 tubby like protein 3 1.5428
RPN2 ribophorin II 1.54262
METAP1 methionyl aminopeptidase 1 1.53996
TMEM37 transmembrane protein 37 1.53986
ACLY ATP citrate lyase 1.53714
HN1 hematological and neurological expressed 1 1.5364
STBD1 starch binding domain 1 1.53615
MKL1 megakaryoblastic leukemia (translocation) 1 1.53524
SLC46A1 solute carrier family 46 (folate transporter), member 1 1.53407
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1.53383
DAXX death-domain associated protein 1.53328
PEPD peptidase D 1.53303
SBDS Shwachman-Bodian-Diamond syndrome 1.53068
BCAS2 breast carcinoma amplified sequence 2 1.53008
LGALS8 lectin, galactoside-binding, soluble, 8 1.52315
HAGH hydroxyacylglutathione hydrolase 1.52223
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.52089
LRRC59 leucine rich repeat containing 59 1.51824
SEPHS2 selenophosphate synthetase 2 1.5178
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.51617
C1ORF158 chromosome 1 open reading frame 158 1.5137
PDCD6IP programmed cell death 6 interacting protein 1.51229
RAB18 RAB18, member RAS oncogene family 1.51189
FBL fibrillarin 1.5112
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 1.50929
RPS11 ribosomal protein S11 1.50854
IFNGR1 interferon gamma receptor 1 1.50282
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.50149
MCL1 myeloid cell leukemia 1 1.50121
LUC7L3 LUC7-like 3 (S. cerevisiae) 1.49824
UCK2 uridine-cytidine kinase 2 1.49753
SKAP2 src kinase associated phosphoprotein 2 1.49671
TMCO1 transmembrane and coiled-coil domains 1 1.49666
IGFBPL1 insulin-like growth factor binding protein-like 1 1.49564
CAV3 caveolin 3 1.49278
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 1.49248
TPP1 tripeptidyl peptidase I 1.49182
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 1.49135
SDHAF1 succinate dehydrogenase complex assembly factor 1 1.4905
IRF9 interferon regulatory factor 9 1.48984
ANPEP alanyl (membrane) aminopeptidase 1.48975
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.48614
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.48521

decreased expression

Symbol Name Standardized Value
C19ORF70 chromosome 19 open reading frame 70 -3.35438
CLK3 CDC-like kinase 3 -3.32802
ELL elongation factor RNA polymerase II -3.21783
MLYCD malonyl-CoA decarboxylase -3.11638
MRPS11 mitochondrial ribosomal protein S11 -2.85501
NLRX1 NLR family member X1 -2.82388
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.80662
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.77481
USP6NL USP6 N-terminal like -2.72991
CCDC12 coiled-coil domain containing 12 -2.59584
RANBP3 RAN binding protein 3 -2.57897
TST thiosulfate sulfurtransferase (rhodanese) -2.57318
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -2.57163
ABHD14A abhydrolase domain containing 14A -2.54191
PUM2 pumilio RNA-binding family member 2 -2.51408
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -2.50822
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 -2.48296
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.45386
CDC16 cell division cycle 16 -2.45064
CDC5L cell division cycle 5-like -2.44074
LARS leucyl-tRNA synthetase -2.41661
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.40654
IMPAD1 inositol monophosphatase domain containing 1 -2.39374
SIVA1 SIVA1, apoptosis-inducing factor -2.3899
SEC24C SEC24 family member C -2.38845
FAM53A family with sequence similarity 53, member A -2.38748
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -2.38249
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.38042
WARS tryptophanyl-tRNA synthetase -2.36705
MRPS31 mitochondrial ribosomal protein S31 -2.35406
INTS5 integrator complex subunit 5 -2.34015
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -2.33477
ZNF598 zinc finger protein 598 -2.33421
DMD dystrophin -2.32544
VAC14 Vac14 homolog (S. cerevisiae) -2.31999
C8ORF37 chromosome 8 open reading frame 37 -2.29809
PRDX2 peroxiredoxin 2 -2.29535
VEGFB vascular endothelial growth factor B -2.24856
NCOR1 nuclear receptor corepressor 1 -2.2356
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -2.23351
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -2.22606
PIGM phosphatidylinositol glycan anchor biosynthesis, class M -2.22101
SPOP speckle-type POZ protein -2.21735
BAG1 BCL2-associated athanogene -2.20682
CLK1 CDC-like kinase 1 -2.19967
YPEL3 yippee-like 3 (Drosophila) -2.18549
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -2.18499
UBXN8 UBX domain protein 8 -2.1757
C7ORF55 chromosome 7 open reading frame 55 -2.15263
STX1A syntaxin 1A (brain) -2.15257
PGF placental growth factor -2.1463
MINOS1 mitochondrial inner membrane organizing system 1 -2.14487
GTF3A general transcription factor IIIA -2.12421
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -2.12264
EIF2A eukaryotic translation initiation factor 2A, 65kDa -2.11548
ABHD16A abhydrolase domain containing 16A -2.09492
DPF2 D4, zinc and double PHD fingers family 2 -2.09155
SEC16A SEC16 homolog A (S. cerevisiae) -2.08738
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -2.08032
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -2.07918
PALM paralemmin -2.07812
PSPH phosphoserine phosphatase -2.06121
COPS3 COP9 signalosome subunit 3 -2.05929
GOLM1 golgi membrane protein 1 -2.0549
CPOX coproporphyrinogen oxidase -2.05409
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.05357
ZBTB45 zinc finger and BTB domain containing 45 -2.04283
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -2.03817
AARS alanyl-tRNA synthetase -2.03544
ASCC1 activating signal cointegrator 1 complex subunit 1 -2.03049
NANS N-acetylneuraminic acid synthase -2.03005
WNT2B wingless-type MMTV integration site family, member 2B -2.02241
KRTCAP2 keratinocyte associated protein 2 -2.01779
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -2.01628
SMS spermine synthase -2.01495
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.00725
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.00175
SATB1 SATB homeobox 1 -1.99441
B9D1 B9 protein domain 1 -1.99329
JMJD6 jumonji domain containing 6 -1.98078
USP39 ubiquitin specific peptidase 39 -1.97684
SOCS2 suppressor of cytokine signaling 2 -1.96953
SAR1A secretion associated, Ras related GTPase 1A -1.96489
PDCD7 programmed cell death 7 -1.95927
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -1.95343
MTOR mechanistic target of rapamycin (serine/threonine kinase) -1.95013
STMN4 stathmin-like 4 -1.94114
ZNRD1 zinc ribbon domain containing 1 -1.93788
TM2D2 TM2 domain containing 2 -1.93213
BRAP BRCA1 associated protein -1.93066
FADS1 fatty acid desaturase 1 -1.92527
NUP62 nucleoporin 62kDa -1.91226
CADM1 cell adhesion molecule 1 -1.91164
CENPV centromere protein V -1.90833
CA1 carbonic anhydrase I -1.89869
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 -1.87828
TBCE tubulin folding cofactor E -1.8758
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -1.86953
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -1.85943
DENND5A DENN/MADD domain containing 5A -1.84994
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -1.84754
SIAE sialic acid acetylesterase -1.8447
PARP6 poly (ADP-ribose) polymerase family, member 6 -1.8352
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 -1.83433
PPP6R3 protein phosphatase 6, regulatory subunit 3 -1.83226
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -1.83068
HINT2 histidine triad nucleotide binding protein 2 -1.82505
HTRA2 HtrA serine peptidase 2 -1.82341
ITGB1BP1 integrin beta 1 binding protein 1 -1.82333
ELMOD3 ELMO/CED-12 domain containing 3 -1.81292
TCOF1 Treacher Collins-Franceschetti syndrome 1 -1.80899
C9ORF69 chromosome 9 open reading frame 69 -1.8053
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.80473
TBC1D14 TBC1 domain family, member 14 -1.80405
NEO1 neogenin 1 -1.80279
JAK1 Janus kinase 1 -1.79599
LBR lamin B receptor -1.79559
ISCA2 iron-sulfur cluster assembly 2 -1.78756
LTV1 LTV1 ribosome biogenesis factor -1.7856
ALAD aminolevulinate dehydratase -1.78128
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 -1.78067
WBP1 WW domain binding protein 1 -1.77446
DTD1 D-tyrosyl-tRNA deacylase 1 -1.76879
MOCS2 molybdenum cofactor synthesis 2 -1.76743
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -1.76628
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 -1.76488
NKX2-8 NK2 homeobox 8 -1.75375
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -1.75164
DLG1 discs, large homolog 1 (Drosophila) -1.74878
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -1.74483
SYF2 SYF2 pre-mRNA-splicing factor -1.73606
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -1.73164
RPL18 ribosomal protein L18 -1.72613
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -1.72531
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase -1.7249
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.71707
ADCY4 adenylate cyclase 4 -1.71256
ETNK1 ethanolamine kinase 1 -1.7105
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.70973
VPRBP Vpr (HIV-1) binding protein -1.70877
SMAP2 small ArfGAP2 -1.70741
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -1.7059
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -1.70167
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -1.69871
PDCD5 programmed cell death 5 -1.689
APMAP adipocyte plasma membrane associated protein -1.68527
IPO5 importin 5 -1.68516
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -1.68381
SMG5 SMG5 nonsense mediated mRNA decay factor -1.67896
CNOT8 CCR4-NOT transcription complex, subunit 8 -1.67809
ZDHHC6 zinc finger, DHHC-type containing 6 -1.6766
ATOX1 antioxidant 1 copper chaperone -1.67473
TMEM179B transmembrane protein 179B -1.67134
HDAC5 histone deacetylase 5 -1.66701
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.66686
POLR1A polymerase (RNA) I polypeptide A, 194kDa -1.66505
FBXL3 F-box and leucine-rich repeat protein 3 -1.66321
EIF3K eukaryotic translation initiation factor 3, subunit K -1.66165
SLC31A1 solute carrier family 31 (copper transporter), member 1 -1.65981
SENP6 SUMO1/sentrin specific peptidase 6 -1.65613
MRPS21 mitochondrial ribosomal protein S21 -1.65429
PES1 pescadillo ribosomal biogenesis factor 1 -1.653
ANAPC13 anaphase promoting complex subunit 13 -1.65272
CBR3 carbonyl reductase 3 -1.65048
PARL presenilin associated, rhomboid-like -1.64895
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 -1.6445
LEMD2 LEM domain containing 2 -1.64207
NUBP1 nucleotide binding protein 1 -1.63978
FAM120A family with sequence similarity 120A -1.63752
UBXN6 UBX domain protein 6 -1.63449
LRPPRC leucine-rich pentatricopeptide repeat containing -1.63415
COPS7B COP9 signalosome subunit 7B -1.63314
APIP APAF1 interacting protein -1.63244
ORC5 origin recognition complex, subunit 5 -1.63086
WNK2 WNK lysine deficient protein kinase 2 -1.62893
IL13 interleukin 13 -1.62632
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -1.62495
ADIPOR2 adiponectin receptor 2 -1.62462
BTD biotinidase -1.61391
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.61107
ANAPC16 anaphase promoting complex subunit 16 -1.61054
ADGRL1 adhesion G protein-coupled receptor L1 -1.60977
ECE1 endothelin converting enzyme 1 -1.60913
PROSC proline synthetase co-transcribed homolog (bacterial) -1.60541
MYL2 myosin, light chain 2, regulatory, cardiac, slow -1.60442
CCDC115 coiled-coil domain containing 115 -1.60308
SLC35B1 solute carrier family 35, member B1 -1.60255
FHL1 four and a half LIM domains 1 -1.59429
COPZ1 coatomer protein complex, subunit zeta 1 -1.59345
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -1.59112
FKBP4 FK506 binding protein 4, 59kDa -1.58955
SMC6 structural maintenance of chromosomes 6 -1.58765
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -1.58485
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -1.58251
RRM1 ribonucleotide reductase M1 -1.58175
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -1.58077
DGUOK deoxyguanosine kinase -1.57898
COQ3 coenzyme Q3 methyltransferase -1.57773
GPS1 G protein pathway suppressor 1 -1.57653
PHPT1 phosphohistidine phosphatase 1 -1.57241
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -1.56958
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 -1.5682
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -1.56658
FBXO6 F-box protein 6 -1.56628
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -1.5662
CA12 carbonic anhydrase XII -1.56541
DAP3 death associated protein 3 -1.56537
CAST calpastatin -1.56244
PON2 paraoxonase 2 -1.55299
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -1.55154
FLT4 fms-related tyrosine kinase 4 -1.54981
GPN2 GPN-loop GTPase 2 -1.5481
MSL1 male-specific lethal 1 homolog (Drosophila) -1.54628
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) -1.54584
ANKH ANKH inorganic pyrophosphate transport regulator -1.54482
TCEA2 transcription elongation factor A (SII), 2 -1.54367
IVD isovaleryl-CoA dehydrogenase -1.54036
MEMO1 mediator of cell motility 1 -1.53778
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -1.537
UNG uracil-DNA glycosylase -1.52981
LRRC8A leucine rich repeat containing 8 family, member A -1.52744
STK11 serine/threonine kinase 11 -1.52081
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -1.51687
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -1.51195
COMMD1 copper metabolism (Murr1) domain containing 1 -1.51189
CLCN4 chloride channel, voltage-sensitive 4 -1.50473
PXMP2 peroxisomal membrane protein 2, 22kDa -1.50279
FIBP fibroblast growth factor (acidic) intracellular binding protein -1.50215
ADORA2A adenosine A2a receptor -1.49725
RAP2B RAP2B, member of RAS oncogene family -1.49647
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -1.49484
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -1.49225
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -1.48769
FGF7 fibroblast growth factor 7 -1.48632
RPS26 ribosomal protein S26 -1.48628
TSPAN33 tetraspanin 33 -1.48602
NUP85 nucleoporin 85kDa -1.48455
PNPT1 polyribonucleotide nucleotidyltransferase 1 -1.48376
SRA1 steroid receptor RNA activator 1 -1.48334
PTPRN protein tyrosine phosphatase, receptor type, N -1.48325
SYNPO synaptopodin -1.48096
C11ORF58 chromosome 11 open reading frame 58 -1.48
RXRA retinoid X receptor, alpha -1.47823
PWP1 PWP1 homolog (S. cerevisiae) -1.47741
SLC10A3 solute carrier family 10, member 3 -1.47666
PRTN3 proteinase 3 -1.47286
FLCN folliculin -1.47285
MEA1 male-enhanced antigen 1 -1.47275
GRIK5 glutamate receptor, ionotropic, kainate 5 -1.47126
MPO myeloperoxidase -1.47123
FH fumarate hydratase -1.46849
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -1.46346
PTEN phosphatase and tensin homolog -1.463
KLF1 Kruppel-like factor 1 (erythroid) -1.46055
RALBP1 ralA binding protein 1 -1.45749
FBXW4 F-box and WD repeat domain containing 4 -1.45688
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -1.45673
RGS3 regulator of G-protein signaling 3 -1.45625
ETFDH electron-transferring-flavoprotein dehydrogenase -1.45277
MSH2 mutS homolog 2 -1.4505
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -1.45036
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -1.44748
MCEE methylmalonyl CoA epimerase -1.44597
TIMP3 TIMP metallopeptidase inhibitor 3 -1.44579
DUSP12 dual specificity phosphatase 12 -1.44499
CXCL12 chemokine (C-X-C motif) ligand 12 -1.44488
TTL tubulin tyrosine ligase -1.44077
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -1.43958
MCM10 minichromosome maintenance complex component 10 -1.43812
PHF23 PHD finger protein 23 -1.43609
KDM3B lysine (K)-specific demethylase 3B -1.43297
REPS1 RALBP1 associated Eps domain containing 1 -1.43133
PRKACB protein kinase, cAMP-dependent, catalytic, beta -1.43011
FAF1 Fas (TNFRSF6) associated factor 1 -1.4252
DHRSX dehydrogenase/reductase (SDR family) X-linked -1.42122
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -1.41574
TOP3B topoisomerase (DNA) III beta -1.4156
HSBP1 heat shock factor binding protein 1 -1.41358
HIGD1A HIG1 hypoxia inducible domain family, member 1A -1.41237
ACTL7B actin-like 7B -1.41224
SVIL supervillin -1.41137
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -1.4108
POU3F2 POU class 3 homeobox 2 -1.40823
C2 complement component 2 -1.39714
FAM162A family with sequence similarity 162, member A -1.39711
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.39588
MRPL21 mitochondrial ribosomal protein L21 -1.39551
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) -1.39405
NXPH4 neurexophilin 4 -1.39403
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -1.3913
FRYL FRY-like -1.39
FZD7 frizzled class receptor 7 -1.38518
MIEN1 migration and invasion enhancer 1 -1.38235
PPARA peroxisome proliferator-activated receptor alpha -1.3802
EPHA8 EPH receptor A8 -1.37916
PEX6 peroxisomal biogenesis factor 6 -1.37704
PTCH1 patched 1 -1.37672
LAPTM4B lysosomal protein transmembrane 4 beta -1.37395
ALAS1 5'-aminolevulinate synthase 1 -1.37377
UBL5 ubiquitin-like 5 -1.37287