Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1008
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Genes

600 genes differentially expressed during Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
SUMO3 small ubiquitin-like modifier 3 4.17959
ANKRD10 ankyrin repeat domain 10 3.524
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.38677
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.25714
C1QB complement component 1, q subcomponent, B chain 3.15262
LGALS1 lectin, galactoside-binding, soluble, 1 2.83237
EIF3K eukaryotic translation initiation factor 3, subunit K 2.8321
LAMP1 lysosomal-associated membrane protein 1 2.77136
UQCRC2 ubiquinol-cytochrome c reductase core protein II 2.75523
C5ORF15 chromosome 5 open reading frame 15 2.75169
MINPP1 multiple inositol-polyphosphate phosphatase 1 2.74928
RPLP0 ribosomal protein, large, P0 2.73479
TBK1 TANK-binding kinase 1 2.66568
CD151 CD151 molecule (Raph blood group) 2.63893
MLEC malectin 2.59609
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 2.51791
CDK8 cyclin-dependent kinase 8 2.51291
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.48642
CAV3 caveolin 3 2.47723
PDCD6IP programmed cell death 6 interacting protein 2.47253
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.46005
PTDSS1 phosphatidylserine synthase 1 2.4584
MCL1 myeloid cell leukemia 1 2.44587
ITCH itchy E3 ubiquitin protein ligase 2.44153
QDPR quinoid dihydropteridine reductase 2.43481
TPI1 triosephosphate isomerase 1 2.4294
PRKD2 protein kinase D2 2.42231
HDAC5 histone deacetylase 5 2.41527
RERE arginine-glutamic acid dipeptide (RE) repeats 2.41406
KLC1 kinesin light chain 1 2.38798
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 2.38713
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.38521
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 2.34226
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 2.32796
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 2.32786
REEP5 receptor accessory protein 5 2.32056
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.31386
ZBTB22 zinc finger and BTB domain containing 22 2.30157
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.28062
BRAP BRCA1 associated protein 2.24452
TAPBP TAP binding protein (tapasin) 2.24228
PRKCB protein kinase C, beta 2.2331
PGK1 phosphoglycerate kinase 1 2.23207
CCNL2 cyclin L2 2.21049
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 2.19686
THUMPD1 THUMP domain containing 1 2.19494
SLC35B1 solute carrier family 35, member B1 2.15458
LGALS9B lectin, galactoside-binding, soluble, 9B 2.12197
BAZ2A bromodomain adjacent to zinc finger domain, 2A 2.11473
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 2.09119
SON SON DNA binding protein 2.08772
CD63 CD63 molecule 2.08689
DBNL drebrin-like 2.07049
IPO4 importin 4 2.03317
MRC1 mannose receptor, C type 1 2.03294
UBA7 ubiquitin-like modifier activating enzyme 7 2.02667
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.02666
CSTB cystatin B (stefin B) 2.02354
TNNT2 troponin T type 2 (cardiac) 2.02291
OAZ2 ornithine decarboxylase antizyme 2 2.0114
MYEOV2 myeloma overexpressed 2 1.9997
ARF1 ADP-ribosylation factor 1 1.99683
MYL7 myosin, light chain 7, regulatory 1.99679
ATOX1 antioxidant 1 copper chaperone 1.99541
FNTA farnesyltransferase, CAAX box, alpha 1.98773
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 1.98276
CTSS cathepsin S 1.97439
PRMT6 protein arginine methyltransferase 6 1.96629
MIDN midnolin 1.96553
TBX6 T-box 6 1.9581
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.95461
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.95133
BROX BRO1 domain and CAAX motif containing 1.94209
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.92965
SRSF4 serine/arginine-rich splicing factor 4 1.92209
GPX4 glutathione peroxidase 4 1.92189
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 1.92063
PPOX protoporphyrinogen oxidase 1.91734
CLK1 CDC-like kinase 1 1.91707
FAM8A1 family with sequence similarity 8, member A1 1.90821
PARP2 poly (ADP-ribose) polymerase 2 1.90324
DCTN2 dynactin 2 (p50) 1.8985
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.89455
MORF4L1 mortality factor 4 like 1 1.89186
FAM120A family with sequence similarity 120A 1.88438
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.87966
GBAS glioblastoma amplified sequence 1.87193
NUCB1 nucleobindin 1 1.87177
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.86938
RLIM ring finger protein, LIM domain interacting 1.86606
TNPO2 transportin 2 1.86529
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.86488
FZD9 frizzled class receptor 9 1.86071
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 1.85992
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 1.85801
NCL nucleolin 1.85477
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa 1.8418
LAMP2 lysosomal-associated membrane protein 2 1.84176
CMIP c-Maf inducing protein 1.83846
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1.83213
CHD1 chromodomain helicase DNA binding protein 1 1.82855
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.81668
ITGA7 integrin, alpha 7 1.8103
APRT adenine phosphoribosyltransferase 1.80787
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 1.80335
DDR1 discoidin domain receptor tyrosine kinase 1 1.8006
SRRT serrate, RNA effector molecule 1.79999
INTS5 integrator complex subunit 5 1.79919
TIMP2 TIMP metallopeptidase inhibitor 2 1.79527
RALBP1 ralA binding protein 1 1.79366
EIF5 eukaryotic translation initiation factor 5 1.79211
MRPS24 mitochondrial ribosomal protein S24 1.79058
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 1.78154
METTL9 methyltransferase like 9 1.77891
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.77862
FUBP1 far upstream element (FUSE) binding protein 1 1.768
JUNB jun B proto-oncogene 1.76123
PCBP2 poly(rC) binding protein 2 1.75966
SRSF2 serine/arginine-rich splicing factor 2 1.75918
TSPO translocator protein (18kDa) 1.75316
SREBF1 sterol regulatory element binding transcription factor 1 1.74865
MEF2D myocyte enhancer factor 2D 1.74716
GLG1 golgi glycoprotein 1 1.74618
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 1.74571
SERINC3 serine incorporator 3 1.73957
GABARAPL1 GABA(A) receptor-associated protein like 1 1.73277
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 1.72562
MYL4 myosin, light chain 4, alkali; atrial, embryonic 1.72518
FOXO3 forkhead box O3 1.72416
PRPF6 pre-mRNA processing factor 6 1.71908
C9ORF114 chromosome 9 open reading frame 114 1.71452
GAS6 growth arrest-specific 6 1.71109
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.71024
TSNAX translin-associated factor X 1.70651
BAD BCL2-associated agonist of cell death 1.70032
RPS7 ribosomal protein S7 1.69318
RPS10 ribosomal protein S10 1.69106
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 1.68788
MDM4 MDM4, p53 regulator 1.68611
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.6854
MYBPH myosin binding protein H 1.68533
PSAPL1 prosaposin-like 1 (gene/pseudogene) 1.68405
TRIM21 tripartite motif containing 21 1.67909
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.67659
UBA2 ubiquitin-like modifier activating enzyme 2 1.6731
MFSD1 major facilitator superfamily domain containing 1 1.67127
GSS glutathione synthetase 1.66858
CXORF38 chromosome X open reading frame 38 1.66501
ANXA6 annexin A6 1.66344
TADA2B transcriptional adaptor 2B 1.66035
ETFB electron-transfer-flavoprotein, beta polypeptide 1.65422
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.64657
HDLBP high density lipoprotein binding protein 1.64462
RPL6 ribosomal protein L6 1.64156
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 1.63349
ARL14EP ADP-ribosylation factor-like 14 effector protein 1.62858
SNCB synuclein, beta 1.627
TNIP1 TNFAIP3 interacting protein 1 1.62693
TMEM205 transmembrane protein 205 1.62518
FLOT2 flotillin 2 1.62273
CAPG capping protein (actin filament), gelsolin-like 1.62206
MAEA macrophage erythroblast attacher 1.62203
CLCN2 chloride channel, voltage-sensitive 2 1.62002
PNP purine nucleoside phosphorylase 1.61184
ADIPOR2 adiponectin receptor 2 1.60991
SYT2 synaptotagmin II 1.60955
MAP2K3 mitogen-activated protein kinase kinase 3 1.60934
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 1.60759
RBM39 RNA binding motif protein 39 1.60615
PNKD paroxysmal nonkinesigenic dyskinesia 1.6
ATG4B autophagy related 4B, cysteine peptidase 1.59992
ADSS adenylosuccinate synthase 1.59888
IL9R interleukin 9 receptor 1.59731
AHNAK AHNAK nucleoprotein 1.59726
TMEM68 transmembrane protein 68 1.59172
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.59073
CETN3 centrin, EF-hand protein, 3 1.58953
CDC37 cell division cycle 37 1.58932
FBXL3 F-box and leucine-rich repeat protein 3 1.58226
SET SET nuclear proto-oncogene 1.58083
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.57683
SF3B3 splicing factor 3b, subunit 3, 130kDa 1.57675
INPP5K inositol polyphosphate-5-phosphatase K 1.57553
FLOT1 flotillin 1 1.5717
SCAMP2 secretory carrier membrane protein 2 1.56705
LGALS4 lectin, galactoside-binding, soluble, 4 1.56695
PTAFR platelet-activating factor receptor 1.56659
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.56566
LIMD1 LIM domains containing 1 1.56318
UBL5 ubiquitin-like 5 1.56313
NUP85 nucleoporin 85kDa 1.56114
SOCS3 suppressor of cytokine signaling 3 1.55278
CD48 CD48 molecule 1.55104
FBXO6 F-box protein 6 1.55013
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 1.55002
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 1.54971
TMEM176B transmembrane protein 176B 1.5491
SYF2 SYF2 pre-mRNA-splicing factor 1.548
FZD4 frizzled class receptor 4 1.54751
GDF5 growth differentiation factor 5 1.546
IRF5 interferon regulatory factor 5 1.53894
C3AR1 complement component 3a receptor 1 1.53419
TMEM106C transmembrane protein 106C 1.53347
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.52442
EBP emopamil binding protein (sterol isomerase) 1.51556
C6ORF62 chromosome 6 open reading frame 62 1.51486
CELF2 CUGBP, Elav-like family member 2 1.51359
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.51079
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.50992
HIPK1 homeodomain interacting protein kinase 1 1.50803
IGF2R insulin-like growth factor 2 receptor 1.50401
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 1.50372
MEF2C myocyte enhancer factor 2C 1.50058
GRN granulin 1.50001
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.4953
SBNO1 strawberry notch homolog 1 (Drosophila) 1.49036
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 1.48906
REXO2 RNA exonuclease 2 1.48841
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 1.48784
BIN1 bridging integrator 1 1.48696
MINOS1 mitochondrial inner membrane organizing system 1 1.48435
SMC6 structural maintenance of chromosomes 6 1.48179
LRRC4B leucine rich repeat containing 4B 1.47987
SMC3 structural maintenance of chromosomes 3 1.4785
USP34 ubiquitin specific peptidase 34 1.47666
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.47491
GJC1 gap junction protein, gamma 1, 45kDa 1.47457
KPNB1 karyopherin (importin) beta 1 1.47418
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.47025
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.46721
HOXD4 homeobox D4 1.46629
LMNA lamin A/C 1.46031
ESR2 estrogen receptor 2 (ER beta) 1.45805
CTSZ cathepsin Z 1.45792
RAB14 RAB14, member RAS oncogene family 1.45435
MAOA monoamine oxidase A 1.45047
EPC1 enhancer of polycomb homolog 1 (Drosophila) 1.45017
GON4L gon-4-like (C. elegans) 1.44601
HHEX hematopoietically expressed homeobox 1.44394
TRIM25 tripartite motif containing 25 1.44174
CDK16 cyclin-dependent kinase 16 1.44049
S100A13 S100 calcium binding protein A13 1.43995
FNBP4 formin binding protein 4 1.43821
UIMC1 ubiquitin interaction motif containing 1 1.4364
HEXA hexosaminidase A (alpha polypeptide) 1.43628
MATN1 matrilin 1, cartilage matrix protein 1.43586
FRMD6 FERM domain containing 6 1.43393
MZT2A mitotic spindle organizing protein 2A 1.43116
PLAC1 placenta-specific 1 1.42763
KL klotho 1.42693
TSEN15 TSEN15 tRNA splicing endonuclease subunit 1.42148
APAF1 apoptotic peptidase activating factor 1 1.41972
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.4191
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.419
NPC1 Niemann-Pick disease, type C1 1.4188
ZFX zinc finger protein, X-linked 1.4184
BTG2 BTG family, member 2 1.418
CRAMP1L Crm, cramped-like (Drosophila) 1.41793
LRRC58 leucine rich repeat containing 58 1.41584
ACTC1 actin, alpha, cardiac muscle 1 1.41565
TLR6 toll-like receptor 6 1.41514
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 1.41324
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.41242
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.41145
RASA3 RAS p21 protein activator 3 1.40793
C7ORF43 chromosome 7 open reading frame 43 1.4055
CDK9 cyclin-dependent kinase 9 1.40511
ZCCHC6 zinc finger, CCHC domain containing 6 1.40439
SMOC2 SPARC related modular calcium binding 2 1.40346
ACIN1 apoptotic chromatin condensation inducer 1 1.40173
RUNX2 runt-related transcription factor 2 1.40003
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 1.39959
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 1.39956
C12ORF57 chromosome 12 open reading frame 57 1.3992
PGRMC2 progesterone receptor membrane component 2 1.39903
SEC11A SEC11 homolog A (S. cerevisiae) 1.3983
SURF4 surfeit 4 1.39582
CDCA7 cell division cycle associated 7 1.39242
C1QC complement component 1, q subcomponent, C chain 1.3913
TNNC1 troponin C type 1 (slow) 1.391
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 1.39087
LGALS3 lectin, galactoside-binding, soluble, 3 1.3905
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.38928
DUSP6 dual specificity phosphatase 6 1.38847
RPL10 ribosomal protein L10 1.38775
IMP3 IMP3, U3 small nucleolar ribonucleoprotein 1.38494
SFXN4 sideroflexin 4 1.38284
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.38213
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 1.38137
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.38025
EGFR epidermal growth factor receptor 1.37915
IRGM immunity-related GTPase family, M 1.37898
IP6K1 inositol hexakisphosphate kinase 1 1.37834
IFITM3 interferon induced transmembrane protein 3 1.37281
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 1.36947
ST5 suppression of tumorigenicity 5 1.36878
RBM14 RNA binding motif protein 14 1.3685
MED28 mediator complex subunit 28 1.36599
ATG13 autophagy related 13 1.36512
FAM49B family with sequence similarity 49, member B 1.36444

decreased expression

Symbol Name Standardized Value
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -3.50942
DMD dystrophin -3.15522
C9ORF64 chromosome 9 open reading frame 64 -2.89622
TMPO thymopoietin -2.8261
PITPNA phosphatidylinositol transfer protein, alpha -2.78215
TRAPPC3 trafficking protein particle complex 3 -2.77437
NIPBL Nipped-B homolog (Drosophila) -2.71159
WRN Werner syndrome, RecQ helicase-like -2.71151
PNOC prepronociceptin -2.70526
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.67058
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -2.62138
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.61215
DNM1L dynamin 1-like -2.58387
FH fumarate hydratase -2.57346
STX12 syntaxin 12 -2.53843
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -2.53734
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -2.52813
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -2.52633
DLAT dihydrolipoamide S-acetyltransferase -2.48965
SOX7 SRY (sex determining region Y)-box 7 -2.47596
MED20 mediator complex subunit 20 -2.47065
PRPF19 pre-mRNA processing factor 19 -2.46222
HSPA9 heat shock 70kDa protein 9 (mortalin) -2.42533
EIF3E eukaryotic translation initiation factor 3, subunit E -2.39541
MRPS18A mitochondrial ribosomal protein S18A -2.38622
MYO1D myosin ID -2.36253
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.35784
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -2.35384
SRP9 signal recognition particle 9kDa -2.34105
BAG2 BCL2-associated athanogene 2 -2.32592
MRPL45 mitochondrial ribosomal protein L45 -2.3179
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -2.31662
USP39 ubiquitin specific peptidase 39 -2.30373
HIGD2A HIG1 hypoxia inducible domain family, member 2A -2.27328
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -2.25505
PEX13 peroxisomal biogenesis factor 13 -2.25463
NR1I2 nuclear receptor subfamily 1, group I, member 2 -2.24924
CCR8 chemokine (C-C motif) receptor 8 -2.24684
HIST2H3A histone cluster 2, H3a -2.24603
MTMR9 myotubularin related protein 9 -2.24517
UNG uracil-DNA glycosylase -2.23665
AGRP agouti related neuropeptide -2.2357
MRPL50 mitochondrial ribosomal protein L50 -2.23478
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -2.22952
HINT2 histidine triad nucleotide binding protein 2 -2.22627
ALAS1 5'-aminolevulinate synthase 1 -2.22452
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 -2.22168
ZNF598 zinc finger protein 598 -2.22027
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -2.21621
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.20197
TXNRD1 thioredoxin reductase 1 -2.20002
HRH1 histamine receptor H1 -2.19786
DENND5A DENN/MADD domain containing 5A -2.18664
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -2.18048
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase -2.17764
AEBP1 AE binding protein 1 -2.16387
NCOR1 nuclear receptor corepressor 1 -2.15322
NUMA1 nuclear mitotic apparatus protein 1 -2.13226
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -2.12916
COQ9 coenzyme Q9 -2.10906
DOCK5 dedicator of cytokinesis 5 -2.10525
EFHD2 EF-hand domain family, member D2 -2.09954
MRPS7 mitochondrial ribosomal protein S7 -2.08906
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.08416
RAE1 ribonucleic acid export 1 -2.06117
MRPL37 mitochondrial ribosomal protein L37 -2.06028
CCDC90B coiled-coil domain containing 90B -2.0593
RESP18 regulated endocrine-specific protein 18 -2.05697
TSC2 tuberous sclerosis 2 -2.05011
UBE2T ubiquitin-conjugating enzyme E2T -2.04411
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -2.03026
GDI2 GDP dissociation inhibitor 2 -2.0299
PHF13 PHD finger protein 13 -2.02023
TCF15 transcription factor 15 (basic helix-loop-helix) -2.01663
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled -2.01222
EYA1 EYA transcriptional coactivator and phosphatase 1 -2.00898
HOXB6 homeobox B6 -2.00879
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -2.00443
MIA3 melanoma inhibitory activity family, member 3 -2.0008
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -1.99838
TXNIP thioredoxin interacting protein -1.99563
STC2 stanniocalcin 2 -1.97589
MRPL21 mitochondrial ribosomal protein L21 -1.96928
TMX2 thioredoxin-related transmembrane protein 2 -1.96265
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -1.96111
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -1.95929
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) -1.95605
VAV1 vav 1 guanine nucleotide exchange factor -1.95239
POLRMT polymerase (RNA) mitochondrial (DNA directed) -1.95113
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -1.95049
TM7SF2 transmembrane 7 superfamily member 2 -1.94494
ZFHX4 zinc finger homeobox 4 -1.9412
CBX3 chromobox homolog 3 -1.94082
EIF3G eukaryotic translation initiation factor 3, subunit G -1.93894
CRNKL1 crooked neck pre-mRNA splicing factor 1 -1.93479
SEC24C SEC24 family member C -1.9304
ANAPC11 anaphase promoting complex subunit 11 -1.92973
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -1.92469
ZMAT3 zinc finger, matrin-type 3 -1.92302
ACY1 aminoacylase 1 -1.91994
BMP6 bone morphogenetic protein 6 -1.91875
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -1.91073
YLPM1 YLP motif containing 1 -1.90571
TOM1L1 target of myb1 (chicken)-like 1 -1.9029
GPS1 G protein pathway suppressor 1 -1.8959
UBAP2 ubiquitin associated protein 2 -1.88641
GFRA3 GDNF family receptor alpha 3 -1.87439
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -1.87042
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -1.86258
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -1.8624
PUM2 pumilio RNA-binding family member 2 -1.86226
PTCH1 patched 1 -1.86156
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -1.85883
ACVR2A activin A receptor, type IIA -1.85046
MTX1 metaxin 1 -1.84996
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.84944
AXIN2 axin 2 -1.84732
COPS7A COP9 signalosome subunit 7A -1.84533
RNF44 ring finger protein 44 -1.83975
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 -1.83365
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -1.82332
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -1.82105
CHRD chordin -1.82077
CD36 CD36 molecule (thrombospondin receptor) -1.81755
CSNK2A1 casein kinase 2, alpha 1 polypeptide -1.81663
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.81488
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -1.81484
BTF3L4 basic transcription factor 3-like 4 -1.81235
MRPL27 mitochondrial ribosomal protein L27 -1.81191
LYRM2 LYR motif containing 2 -1.80798
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.80108
OPRM1 opioid receptor, mu 1 -1.79168
C9ORF91 chromosome 9 open reading frame 91 -1.78841
MACROD2 MACRO domain containing 2 -1.78711
NNAT neuronatin -1.78593
TFF3 trefoil factor 3 (intestinal) -1.78432
SNAP23 synaptosomal-associated protein, 23kDa -1.78424
MRPL43 mitochondrial ribosomal protein L43 -1.78316
KIAA1524 KIAA1524 -1.77782
UBTD2 ubiquitin domain containing 2 -1.77647
PCGF2 polycomb group ring finger 2 -1.77566
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.7692
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -1.76658
CD6 CD6 molecule -1.7662
APOA1 apolipoprotein A-I -1.75829
CTSC cathepsin C -1.75783
RFC2 replication factor C (activator 1) 2, 40kDa -1.75477
SPRYD4 SPRY domain containing 4 -1.75431
LRRC59 leucine rich repeat containing 59 -1.75175
SELK selenoprotein K -1.75149
SLC25A39 solute carrier family 25, member 39 -1.7503
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D -1.74178
TOP3B topoisomerase (DNA) III beta -1.74165
CUL1 cullin 1 -1.7411
MSL1 male-specific lethal 1 homolog (Drosophila) -1.74068
PLP1 proteolipid protein 1 -1.7406
FZD7 frizzled class receptor 7 -1.74008
ACP6 acid phosphatase 6, lysophosphatidic -1.73772
CDH4 cadherin 4, type 1, R-cadherin (retinal) -1.73692
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.73677
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -1.73619
GAA glucosidase, alpha; acid -1.73132
CRB3 crumbs family member 3 -1.72858
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -1.72828
APOA5 apolipoprotein A-V -1.72662
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -1.72543
LMO1 LIM domain only 1 (rhombotin 1) -1.72511
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -1.72477
SFPQ splicing factor proline/glutamine-rich -1.72453
FTO fat mass and obesity associated -1.72266
UHRF1BP1 UHRF1 binding protein 1 -1.7224
CAMLG calcium modulating ligand -1.72205
MRPL38 mitochondrial ribosomal protein L38 -1.72148
MRPS2 mitochondrial ribosomal protein S2 -1.71368
MRPL3 mitochondrial ribosomal protein L3 -1.71295
PER3 period circadian clock 3 -1.70996
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -1.70887
C1QBP complement component 1, q subcomponent binding protein -1.70628
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -1.7039
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.69761
PELO pelota homolog (Drosophila) -1.69269
AGRN agrin -1.6918
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) -1.69045
SDHAF1 succinate dehydrogenase complex assembly factor 1 -1.6892
OVGP1 oviductal glycoprotein 1, 120kDa -1.68529
AP3B1 adaptor-related protein complex 3, beta 1 subunit -1.68241
NOTCH3 notch 3 -1.67746
ERO1L ERO1-like (S. cerevisiae) -1.67684
IRAK1 interleukin-1 receptor-associated kinase 1 -1.67653
TMED8 transmembrane emp24 protein transport domain containing 8 -1.67545
METTL5 methyltransferase like 5 -1.67524
STAG2 stromal antigen 2 -1.66804
HDAC6 histone deacetylase 6 -1.66048
HSPA8 heat shock 70kDa protein 8 -1.65923
XPO7 exportin 7 -1.65714
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -1.65317
CAND1 cullin-associated and neddylation-dissociated 1 -1.64511
TYSND1 trypsin domain containing 1 -1.63814
TLN1 talin 1 -1.63621
ACO2 aconitase 2, mitochondrial -1.63499
CHMP1B charged multivesicular body protein 1B -1.63458
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -1.63049
PGLS 6-phosphogluconolactonase -1.62804
GABPB1 GA binding protein transcription factor, beta subunit 1 -1.62495
ITSN1 intersectin 1 (SH3 domain protein) -1.6207
SLC30A4 solute carrier family 30 (zinc transporter), member 4 -1.61793
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -1.61335
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -1.61293
THBD thrombomodulin -1.60794
SNX2 sorting nexin 2 -1.60504
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) -1.6046
FOXA2 forkhead box A2 -1.6029
CHD8 chromodomain helicase DNA binding protein 8 -1.60086
DRG1 developmentally regulated GTP binding protein 1 -1.59955
EDN1 endothelin 1 -1.59945
PARP6 poly (ADP-ribose) polymerase family, member 6 -1.59617
SLIRP SRA stem-loop interacting RNA binding protein -1.5895
TMEM199 transmembrane protein 199 -1.58861
CCNT1 cyclin T1 -1.58559
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -1.58476
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -1.58371
MOB1B MOB kinase activator 1B -1.58322
BANF1 barrier to autointegration factor 1 -1.57849
TGFBR3 transforming growth factor, beta receptor III -1.57735
PADI1 peptidyl arginine deiminase, type I -1.57642
VRK3 vaccinia related kinase 3 -1.57586
FOXD2 forkhead box D2 -1.57305
RTN4 reticulon 4 -1.57167
ANKRD17 ankyrin repeat domain 17 -1.56837
NSDHL NAD(P) dependent steroid dehydrogenase-like -1.56689
TM4SF5 transmembrane 4 L six family member 5 -1.56636
SOD2 superoxide dismutase 2, mitochondrial -1.56555
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -1.56522
FBXW2 F-box and WD repeat domain containing 2 -1.55913
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 -1.55792
LDAH lipid droplet associated hydrolase -1.5545
TRAF3 TNF receptor-associated factor 3 -1.5525
ARL5A ADP-ribosylation factor-like 5A -1.55248
RAP2B RAP2B, member of RAS oncogene family -1.55218
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -1.55031
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.54952
ZC3H14 zinc finger CCCH-type containing 14 -1.54628
ACOT13 acyl-CoA thioesterase 13 -1.54399
SPOP speckle-type POZ protein -1.54317
GPN2 GPN-loop GTPase 2 -1.53658
LARP7 La ribonucleoprotein domain family, member 7 -1.53384
CDKN2AIPNL CDKN2A interacting protein N-terminal like -1.5287
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -1.52219
FGF18 fibroblast growth factor 18 -1.51886
RFC3 replication factor C (activator 1) 3, 38kDa -1.51709
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.51626
NCOA1 nuclear receptor coactivator 1 -1.51616
APC adenomatous polyposis coli -1.51406
SRCAP Snf2-related CREBBP activator protein -1.51367
CWC15 CWC15 spliceosome-associated protein -1.51326
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -1.5123
CACUL1 CDK2-associated, cullin domain 1 -1.50839
TCOF1 Treacher Collins-Franceschetti syndrome 1 -1.50299
TMEM150A transmembrane protein 150A -1.50113
CA14 carbonic anhydrase XIV -1.50016
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -1.49884
THAP4 THAP domain containing 4 -1.49657
PREPL prolyl endopeptidase-like -1.49467
CDT1 chromatin licensing and DNA replication factor 1 -1.49191
LCT lactase -1.48943
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 -1.48864
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -1.48812
BRD1 bromodomain containing 1 -1.48544
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.48476
TENM3 teneurin transmembrane protein 3 -1.4843
OC90 otoconin 90 -1.48378
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.483
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -1.48138
CINP cyclin-dependent kinase 2 interacting protein -1.48115
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -1.4781
VAMP8 vesicle-associated membrane protein 8 -1.47785
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -1.47557
EMC3 ER membrane protein complex subunit 3 -1.47346
TMBIM1 transmembrane BAX inhibitor motif containing 1 -1.4656
NCOR2 nuclear receptor corepressor 2 -1.46518
DNPEP aspartyl aminopeptidase -1.46515
SOX13 SRY (sex determining region Y)-box 13 -1.46454
GORASP2 golgi reassembly stacking protein 2, 55kDa -1.46276
CAT catalase -1.45992
RDH16 retinol dehydrogenase 16 (all-trans) -1.4591
HIGD1A HIG1 hypoxia inducible domain family, member 1A -1.458
RBPJ recombination signal binding protein for immunoglobulin kappa J region -1.45563
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -1.45431
FAM134A family with sequence similarity 134, member A -1.45397
PIPOX pipecolic acid oxidase -1.45376
SNIP1 Smad nuclear interacting protein 1 -1.45298
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase -1.45189
FAM53A family with sequence similarity 53, member A -1.45105
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -1.45058
HOXD10 homeobox D10 -1.45057
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.45018
ITGA8 integrin, alpha 8 -1.44902
RPN1 ribophorin I -1.44821
C5AR1 complement component 5a receptor 1 -1.44742
TEKT2 tektin 2 (testicular) -1.44699