Dopamine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group. (Chemical Entities of Biological Interest Ontology, CHEBI_18243)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004298
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Genes

108 genes/proteins interacting with the chemical Dopamine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ADORA1 adenosine A1 receptor
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAT catalase
CHRM5 cholinergic receptor, muscarinic 5
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
COMT catechol-O-methyltransferase
CPT1A carnitine palmitoyltransferase 1A (liver)
CREB1 cAMP responsive element binding protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EN1 engrailed homeobox 1
EN2 engrailed homeobox 2
FOS FBJ murine osteosarcoma viral oncogene homolog
G6PD glucose-6-phosphate dehydrogenase
GCH1 GTP cyclohydrolase 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDNF glial cell derived neurotrophic factor
GHRL ghrelin/obestatin prepropeptide
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRK6 G protein-coupled receptor kinase 6
GRM5 glutamate receptor, metabotropic 5
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HCRTR1 hypocretin (orexin) receptor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HRH1 histamine receptor H1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
INS insulin
JUN jun proto-oncogene
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NPPC natriuretic peptide C
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTF3 neurotrophin 3
OPRK1 opioid receptor, kappa 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PINK1 PTEN induced putative kinase 1
POMC proopiomelanocortin
PRKCD protein kinase C, delta
PRL prolactin
RGS3 regulator of G-protein signaling 3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCT secretin
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SYN1 synapsin I
SYN2 synapsin II
SYN3 synapsin III
TAAR1 trace amine associated receptor 1
TDO2 tryptophan 2,3-dioxygenase
TH tyrosine hydroxylase
TNF tumor necrosis factor
TP53 tumor protein p53