Diseases in Twins Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

129 genes associated with the Diseases in Twins phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOC4 apolipoprotein C-IV
APOE apolipoprotein E
ARHGAP10 Rho GTPase activating protein 10
ARID1B AT rich interactive domain 1B (SWI1-like)
ARMS2 age-related maculopathy susceptibility 2
ASIC1 acid sensing (proton gated) ion channel 1
ATXN1 ataxin 1
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
C2 complement component 2
C3 complement component 3
CDH13 cadherin 13
CETP cholesteryl ester transfer protein, plasma
CFB complement factor B
CFH complement factor H
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLU clusterin
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DISC1 disrupted in schizophrenia 1
DNAH5 dynein, axonemal, heavy chain 5
DRD4 dopamine receptor D4
DYX1C1 dyslexia susceptibility 1 candidate 1
ESR1 estrogen receptor 1
FLG filaggrin
FLNC filamin C, gamma
GAB2 GRB2-associated binding protein 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GJB2 gap junction protein, beta 2, 26kDa
GRIK1 glutamate receptor, ionotropic, kainate 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HFE hemochromatosis
HK1 hexokinase 1
HKDC1 hexokinase domain containing 1
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGF2 insulin-like growth factor 2
IL12B interleukin 12B
IL16 interleukin 16
IL6 interleukin 6
INS insulin
KL klotho
LCAT lecithin-cholesterol acyltransferase
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LIPC lipase, hepatic
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LTA4H leukotriene A4 hydrolase
MAOA monoamine oxidase A
MARK1 MAP/microtubule affinity-regulating kinase 1
MFSD6 major facilitator superfamily domain containing 6
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NUAK1 NUAK family, SNF1-like kinase, 1
NXPH1 neurexophilin 1
OASL 2'-5'-oligoadenylate synthetase-like
PHF11 PHD finger protein 11
PLXNA2 plexin A2
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKG1 protein kinase, cGMP-dependent, type I
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
S100B S100 calcium binding protein B
SAMD3 sterile alpha motif domain containing 3
SFTPB surfactant protein B
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLIT3 slit homolog 3 (Drosophila)
SOD2 superoxide dismutase 2, mitochondrial
TCERG1L transcription elongation regulator 1-like
TNF tumor necrosis factor
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TRAF3IP2 TRAF3 interacting protein 2
TSNAX translin-associated factor X
UNC79 unc-79 homolog (C. elegans)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A