Diabetic Retinopathy Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D003930
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Genes

85 genes/proteins associated with the disease Diabetic Retinopathy from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
VEGFA vascular endothelial growth factor A 2.88009
AGTR1 angiotensin II receptor, type 1 2.88009
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.88009
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.88009
SIRT1 sirtuin 1 2.88009
SOD1 superoxide dismutase 1, soluble 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.88009
ICAM1 intercellular adhesion molecule 1 2.88009
THBS1 thrombospondin 1 2.88009
PON1 paraoxonase 1 2.88009
VCAM1 vascular cell adhesion molecule 1 1.76443
NOS2 nitric oxide synthase 2, inducible 1.7255
TGFB1 transforming growth factor, beta 1 1.69972
TNF tumor necrosis factor 1.63899
CCL2 chemokine (C-C motif) ligand 2 1.61154
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.59218
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.49045
IL1B interleukin 1, beta 1.48017
IL6 interleukin 6 1.44817
APP amyloid beta (A4) precursor protein 1.43266
NOS3 nitric oxide synthase 3 (endothelial cell) 1.38527
MAPK3 mitogen-activated protein kinase 3 1.36133
SOD2 superoxide dismutase 2, mitochondrial 1.35906
TIMP1 TIMP metallopeptidase inhibitor 1 1.35705
MAPK1 mitogen-activated protein kinase 1 1.35299
CTGF connective tissue growth factor 1.33553
IFNG interferon, gamma 1.33199
APOA1 apolipoprotein A-I 1.32964
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.32726
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.31776
CXCL8 chemokine (C-X-C motif) ligand 8 1.29936
CYBA cytochrome b-245, alpha polypeptide 1.2975
ALB albumin 1.29595
HSPB1 heat shock 27kDa protein 1 1.29564
FN1 fibronectin 1 1.26483
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.2599
TP53 tumor protein p53 1.2509
INS insulin 1.24966
MAPK8 mitogen-activated protein kinase 8 1.24781
CAT catalase 1.24623
BAX BCL2-associated X protein 1.23712
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.23584
LEP leptin 1.23169
F2 coagulation factor II (thrombin) 1.22501
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.21076
NOX4 NADPH oxidase 4 1.19672
BCL2 B-cell CLL/lymphoma 2 1.18981
NQO1 NAD(P)H dehydrogenase, quinone 1 1.166
PPARG peroxisome proliferator-activated receptor gamma 1.16567
PPARD peroxisome proliferator-activated receptor delta 1.16302
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.1607
EDN1 endothelin 1 1.15933
GLO1 glyoxalase I 1.15695
PPARA peroxisome proliferator-activated receptor alpha 1.14438
APOB apolipoprotein B 1.13758
HMOX1 heme oxygenase 1 1.13586
MMP2 matrix metallopeptidase 2 1.13211
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.13211
CCND1 cyclin D1 1.12771
ATF3 activating transcription factor 3 1.12461
SELE selectin E 1.1129
MMP13 matrix metallopeptidase 13 1.10872
CCL5 chemokine (C-C motif) ligand 5 1.10493
CAV1 caveolin 1, caveolae protein, 22kDa 1.09471
GSK3B glycogen synthase kinase 3 beta 1.09436
SCARB1 scavenger receptor class B, member 1 1.09332
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.08549
MMP7 matrix metallopeptidase 7 1.07732
CPT1B carnitine palmitoyltransferase 1B (muscle) 1.07269
S100B S100 calcium binding protein B 1.05936
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.05237
UNG uracil-DNA glycosylase 1.04389
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.04314
CD36 CD36 molecule (thrombospondin receptor) 1.03789
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.03752
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.03604
PLAT plasminogen activator, tissue 1.0353
BAD BCL2-associated agonist of cell death 1.03419
APOE apolipoprotein E 1.03197
NPPA natriuretic peptide A 1.02746
INSR insulin receptor 1.01625
MPO myeloperoxidase 1.01549
ADIPOQ adiponectin, C1Q and collagen domain containing 1.01437