Diabetic Neuropathy_Sciatic Nerve_GSE11343 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE11343
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Genes

600 genes differentially expressed during Diabetic Neuropathy_Sciatic Nerve_GSE11343 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 3.80019
PHRF1 PHD and ring finger domains 1 3.79889
VWA3A von Willebrand factor A domain containing 3A 3.34467
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 3.33346
LRRC47 leucine rich repeat containing 47 3.30811
TMEM147 transmembrane protein 147 3.22006
MED4 mediator complex subunit 4 3.18724
RPL8 ribosomal protein L8 3.04069
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.98422
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.88411
HDGF hepatoma-derived growth factor 2.77438
PGPEP1L pyroglutamyl-peptidase I-like 2.77097
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.74802
PLAC1 placenta-specific 1 2.72646
THOC5 THO complex 5 2.70717
EIF3G eukaryotic translation initiation factor 3, subunit G 2.67507
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.67267
ZNF773 zinc finger protein 773 2.66355
PIH1D1 PIH1 domain containing 1 2.6529
ADRA2C adrenoceptor alpha 2C 2.63993
LHB luteinizing hormone beta polypeptide 2.63321
ADIPOR2 adiponectin receptor 2 2.62634
FBL fibrillarin 2.57205
UMODL1 uromodulin-like 1 2.56919
INTS9 integrator complex subunit 9 2.56432
CELA3B chymotrypsin-like elastase family, member 3B 2.55834
GCM1 glial cells missing homolog 1 (Drosophila) 2.54335
ADRBK1 adrenergic, beta, receptor kinase 1 2.51582
GPATCH4 G patch domain containing 4 2.47622
SLC38A9 solute carrier family 38, member 9 2.46406
FCF1 FCF1 rRNA-processing protein 2.4501
H2AFX H2A histone family, member X 2.41061
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) 2.39726
CDH23 cadherin-related 23 2.38393
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.3755
C1ORF210 chromosome 1 open reading frame 210 2.3725
ABHD16A abhydrolase domain containing 16A 2.37124
LOC101928761 2.36164
CAPN11 calpain 11 2.35345
MST1 macrophage stimulating 1 2.32195
MTMR3 myotubularin related protein 3 2.29374
ALPP alkaline phosphatase, placental 2.26622
CDAN1 codanin 1 2.26481
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.26188
AKAP5 A kinase (PRKA) anchor protein 5 2.2572
RPL18A ribosomal protein L18a 2.23889
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 2.19786
CFAP70 cilia and flagella associated protein 70 2.19737
RPS29 ribosomal protein S29 2.19223
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 2.17854
PARK2 parkin RBR E3 ubiquitin protein ligase 2.17239
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 2.16676
TFAM transcription factor A, mitochondrial 2.16503
CTSF cathepsin F 2.16087
DYM dymeclin 2.15179
LRRC8A leucine rich repeat containing 8 family, member A 2.1495
SAC3D1 SAC3 domain containing 1 2.14728
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) 2.14714
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.13741
INTS7 integrator complex subunit 7 2.1348
COQ9 coenzyme Q9 2.11901
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.1158
OGFR opioid growth factor receptor 2.11062
IMP3 IMP3, U3 small nucleolar ribonucleoprotein 2.10178
TFE3 transcription factor binding to IGHM enhancer 3 2.08968
DPF3 D4, zinc and double PHD fingers, family 3 2.08719
SDAD1 SDA1 domain containing 1 2.08573
RPL24 ribosomal protein L24 2.07754
CD4 CD4 molecule 2.07493
VWA3B von Willebrand factor A domain containing 3B 2.07154
CRY2 cryptochrome circadian clock 2 2.06133
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 2.05568
PNPO pyridoxamine 5'-phosphate oxidase 2.04948
FAM131C family with sequence similarity 131, member C 2.0444
RPS23 ribosomal protein S23 2.0398
PRDM9 PR domain containing 9 2.03063
ZNF32 zinc finger protein 32 2.02239
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.00721
RPS15 ribosomal protein S15 2.00244
RGS3 regulator of G-protein signaling 3 1.99952
WDR78 WD repeat domain 78 1.99644
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.99597
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 1.99363
SSBP4 single stranded DNA binding protein 4 1.98349
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.97766
ANXA2 annexin A2 1.9766
PDILT protein disulfide isomerase-like, testis expressed 1.97046
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.96687
CHRM1 cholinergic receptor, muscarinic 1 1.95584
SLC25A34 solute carrier family 25, member 34 1.94571
MAK16 MAK16 homolog (S. cerevisiae) 1.94221
LOC100505841 zinc finger protein 474-like 1.94163
C7ORF25 chromosome 7 open reading frame 25 1.93956
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 1.93366
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.93176
EIF4A3 eukaryotic translation initiation factor 4A3 1.92398
F2RL3 coagulation factor II (thrombin) receptor-like 3 1.92324
FAM98C family with sequence similarity 98, member C 1.92285
RPL37 ribosomal protein L37 1.92122
PNLIPRP1 pancreatic lipase-related protein 1 1.91298
PTX4 pentraxin 4, long 1.91206
GMEB1 glucocorticoid modulatory element binding protein 1 1.90047
DUSP9 dual specificity phosphatase 9 1.89936
FSHB follicle stimulating hormone, beta polypeptide 1.89658
PSEN2 presenilin 2 1.89313
HDDC2 HD domain containing 2 1.8918
FAM50A family with sequence similarity 50, member A 1.86962
TIGAR TP53 induced glycolysis regulatory phosphatase 1.86459
LIPH lipase, member H 1.86415
ZNF622 zinc finger protein 622 1.86193
MATK megakaryocyte-associated tyrosine kinase 1.85637
RP1 retinitis pigmentosa 1 (autosomal dominant) 1.85589
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.85584
TRPC4 transient receptor potential cation channel, subfamily C, member 4 1.84492
CDCA3 cell division cycle associated 3 1.83419
COPS5 COP9 signalosome subunit 5 1.83319
BRAP BRCA1 associated protein 1.82731
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 1.81112
UBE2E2 ubiquitin-conjugating enzyme E2E 2 1.80373
KATNB1 katanin p80 (WD repeat containing) subunit B 1 1.80202
PTOV1 prostate tumor overexpressed 1 1.79806
F12 coagulation factor XII (Hageman factor) 1.79788
FEM1C fem-1 homolog c (C. elegans) 1.79761
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 1.7865
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 1.78248
MUC20 mucin 20, cell surface associated 1.78016
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 1.77361
TSNAXIP1 translin-associated factor X interacting protein 1 1.77289
CCDC94 coiled-coil domain containing 94 1.77249
RPL7L1 ribosomal protein L7-like 1 1.76963
MAD2L1BP MAD2L1 binding protein 1.7686
TCTEX1D4 Tctex1 domain containing 4 1.76844
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 1.76615
COQ10A coenzyme Q10 homolog A (S. cerevisiae) 1.76236
CDK16 cyclin-dependent kinase 16 1.75744
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 1.75373
TEX101 testis expressed 101 1.74642
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.7453
ADIPOR1 adiponectin receptor 1 1.74446
TMEM8C transmembrane protein 8C 1.74429
LTA lymphotoxin alpha 1.73465
AVPR2 arginine vasopressin receptor 2 1.72379
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.72084
PGP phosphoglycolate phosphatase 1.71648
KCNK16 potassium channel, two pore domain subfamily K, member 16 1.70757
NFYC nuclear transcription factor Y, gamma 1.70692
RANBP3 RAN binding protein 3 1.70508
SLC26A1 solute carrier family 26 (anion exchanger), member 1 1.70414
OVOL1 ovo-like zinc finger 1 1.70116
TFF2 trefoil factor 2 1.69827
ASB10 ankyrin repeat and SOCS box containing 10 1.69803
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 1.69685
ZNF750 zinc finger protein 750 1.69276
AGXT2 alanine--glyoxylate aminotransferase 2 1.68799
CCDC83 coiled-coil domain containing 83 1.68169
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) 1.6815
SPATA2 spermatogenesis associated 2 1.68043
MYBPHL myosin binding protein H-like 1.68001
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.67897
NGDN neuroguidin, EIF4E binding protein 1.67549
KANSL2 KAT8 regulatory NSL complex subunit 2 1.67431
TECTB tectorin beta 1.6732
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1.6664
RHO rhodopsin 1.6638
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.66334
CMIP c-Maf inducing protein 1.65963
POU2F3 POU class 2 homeobox 3 1.65797
UFSP1 UFM1-specific peptidase 1 (non-functional) 1.65332
PSAPL1 prosaposin-like 1 (gene/pseudogene) 1.6519
WDR37 WD repeat domain 37 1.65104
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 1.65019
TCP11X2 t-complex 11 family, X-linked 2 1.64644
LYST lysosomal trafficking regulator 1.64047
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 1.63669
DMBX1 diencephalon/mesencephalon homeobox 1 1.63417
CCDC22 coiled-coil domain containing 22 1.63335
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.62881
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 1.62677
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.62576
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.62377
GLP1R glucagon-like peptide 1 receptor 1.62168
MRPS18C mitochondrial ribosomal protein S18C 1.61971
ACVR1B activin A receptor, type IB 1.61847
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 1.61417
DLD dihydrolipoamide dehydrogenase 1.61337
LY6E lymphocyte antigen 6 complex, locus E 1.6108
AQP2 aquaporin 2 (collecting duct) 1.60922
EPHA4 EPH receptor A4 1.60714
TOX4 TOX high mobility group box family member 4 1.59993
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.5954
KLHL36 kelch-like family member 36 1.59373
LYPD8 LY6/PLAUR domain containing 8 1.59302
CRYBB2 crystallin, beta B2 1.59066
NUP50 nucleoporin 50kDa 1.58896
FURIN furin (paired basic amino acid cleaving enzyme) 1.58729
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 1.58689
BHLHE23 basic helix-loop-helix family, member e23 1.58572
MAT1A methionine adenosyltransferase I, alpha 1.58164
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 1.57774
CCDC110 coiled-coil domain containing 110 1.57616
HAND1 heart and neural crest derivatives expressed 1 1.57277
CLNS1A chloride channel, nucleotide-sensitive, 1A 1.57034
ATG7 autophagy related 7 1.56824
SELV selenoprotein V 1.56666
KPNA7 karyopherin alpha 7 (importin alpha 8) 1.55798
MASTL microtubule associated serine/threonine kinase-like 1.55526
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.55163
XAB2 XPA binding protein 2 1.5516
FAM50B family with sequence similarity 50, member B 1.55132
EQTN equatorin, sperm acrosome associated 1.54497
GPANK1 G patch domain and ankyrin repeats 1 1.54385
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 1.54375
CER1 cerberus 1, DAN family BMP antagonist 1.54314
TEX22 testis expressed 22 1.539
TSSK2 testis-specific serine kinase 2 1.53233
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.53204
GEMIN5 gem (nuclear organelle) associated protein 5 1.53039
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 1.52766
ODF3 outer dense fiber of sperm tails 3 1.52674
LALBA lactalbumin, alpha- 1.52109
PRDM4 PR domain containing 4 1.51684
UNC13B unc-13 homolog B (C. elegans) 1.51606
ZBTB43 zinc finger and BTB domain containing 43 1.51476
TMEM217 transmembrane protein 217 1.51295
ATF7IP2 activating transcription factor 7 interacting protein 2 1.5098
NKPD1 NTPase, KAP family P-loop domain containing 1 1.50979
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 1.50436
ADAM2 ADAM metallopeptidase domain 2 1.50414
ITK IL2-inducible T-cell kinase 1.49985
TRIM11 tripartite motif containing 11 1.49857
LRRC20 leucine rich repeat containing 20 1.49538
BPHL biphenyl hydrolase-like (serine hydrolase) 1.48966
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 1.48904
OC90 otoconin 90 1.48489
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 1.48434
NLGN2 neuroligin 2 1.48334
JKAMP JNK1/MAPK8-associated membrane protein 1.4781
STK24 serine/threonine kinase 24 1.47655
C19ORF45 chromosome 19 open reading frame 45 1.47596
MRPS35 mitochondrial ribosomal protein S35 1.47287
ATXN7L2 ataxin 7-like 2 1.47283
GFM1 G elongation factor, mitochondrial 1 1.47126
SYMPK symplekin 1.46904
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 1.46659
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 1.46584
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 1.46503
NANOS1 nanos homolog 1 (Drosophila) 1.46377
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.45953
REPS1 RALBP1 associated Eps domain containing 1 1.45791
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 1.45537
FAM63A family with sequence similarity 63, member A 1.45461
C4ORF36 chromosome 4 open reading frame 36 1.45375
PLCB2 phospholipase C, beta 2 1.45358
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 1.45059
PAIP2B poly(A) binding protein interacting protein 2B 1.449
IPO7 importin 7 1.44781
PMPCA peptidase (mitochondrial processing) alpha 1.4477
PRPF4 pre-mRNA processing factor 4 1.4454
EIF6 eukaryotic translation initiation factor 6 1.44285
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 1.43886
C6ORF201 chromosome 6 open reading frame 201 1.43473
NKX2-1 NK2 homeobox 1 1.4278
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 1.42491
UBASH3A ubiquitin associated and SH3 domain containing A 1.4242
TCF21 transcription factor 21 1.42192
NKX2-8 NK2 homeobox 8 1.4199
WNT8B wingless-type MMTV integration site family, member 8B 1.41916
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.41769
GINS4 GINS complex subunit 4 (Sld5 homolog) 1.41755
IQCA1 IQ motif containing with AAA domain 1 1.41574
NUP133 nucleoporin 133kDa 1.41332
TMPRSS3 transmembrane protease, serine 3 1.40924
STYXL1 serine/threonine/tyrosine interacting-like 1 1.40688
FOXG1 forkhead box G1 1.40581
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 1.405
GON4L gon-4-like (C. elegans) 1.40114
C8ORF74 chromosome 8 open reading frame 74 1.39935
ZNF703 zinc finger protein 703 1.39397
PPP3R2 protein phosphatase 3, regulatory subunit B, beta 1.39241
RPS7 ribosomal protein S7 1.39223
EXOSC4 exosome component 4 1.3912
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) 1.38973
KIF3B kinesin family member 3B 1.38451
UROD uroporphyrinogen decarboxylase 1.38371
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 1.3817
FEV FEV (ETS oncogene family) 1.38157
HOXD12 homeobox D12 1.38
ADGRB1 adhesion G protein-coupled receptor B1 1.37908
PHF5A PHD finger protein 5A 1.376
TICRR TOPBP1-interacting checkpoint and replication regulator 1.37597
COMMD9 COMM domain containing 9 1.37418
SLC45A2 solute carrier family 45, member 2 1.37127
CLDN7 claudin 7 1.3651
C5 complement component 5 1.36488
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.36198
IFI35 interferon-induced protein 35 1.36169
CSNK1D casein kinase 1, delta 1.36019
KIAA0319L KIAA0319-like 1.35681
CTRC chymotrypsin C (caldecrin) 1.3558
EVX1 even-skipped homeobox 1 1.35441

decreased expression

Symbol Name Standardized Value
PAIP2 poly(A) binding protein interacting protein 2 -4.52403
HIST1H2BI histone cluster 1, H2bi -3.50321
CDK12 cyclin-dependent kinase 12 -3.30105
COMMD3 COMM domain containing 3 -3.1649
CCDC88A coiled-coil domain containing 88A -3.11531
SERF2 small EDRK-rich factor 2 -3.08808
CACUL1 CDK2-associated, cullin domain 1 -3.06791
PHACTR2 phosphatase and actin regulator 2 -2.97566
VBP1 von Hippel-Lindau binding protein 1 -2.9582
TRA2A transformer 2 alpha homolog (Drosophila) -2.90846
RPL10A ribosomal protein L10a -2.89865
MBOAT7 membrane bound O-acyltransferase domain containing 7 -2.81918
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.80089
COL11A1 collagen, type XI, alpha 1 -2.76193
RPS8 ribosomal protein S8 -2.74097
MED28 mediator complex subunit 28 -2.72122
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -2.70734
CD81 CD81 molecule -2.70308
TMED4 transmembrane emp24 protein transport domain containing 4 -2.66536
FAM32A family with sequence similarity 32, member A -2.64412
RPL23 ribosomal protein L23 -2.64254
CLTC clathrin, heavy chain (Hc) -2.63017
TNRC6A trinucleotide repeat containing 6A -2.62045
NF1 neurofibromin 1 -2.61654
ZMYM2 zinc finger, MYM-type 2 -2.58614
RPL7 ribosomal protein L7 -2.58203
TMX3 thioredoxin-related transmembrane protein 3 -2.56558
HIST1H2BJ histone cluster 1, H2bj -2.53866
DPY19L1 dpy-19-like 1 (C. elegans) -2.48338
CFDP1 craniofacial development protein 1 -2.44702
IL10RB interleukin 10 receptor, beta -2.4292
PAPOLA poly(A) polymerase alpha -2.39937
DARS aspartyl-tRNA synthetase -2.39492
PRDX1 peroxiredoxin 1 -2.33688
IST1 increased sodium tolerance 1 homolog (yeast) -2.32585
MIER2 mesoderm induction early response 1, family member 2 -2.3205
RBM12 RNA binding motif protein 12 -2.30222
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -2.29696
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -2.282
ZNF317 zinc finger protein 317 -2.26817
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.2518
C9ORF40 chromosome 9 open reading frame 40 -2.23933
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.22469
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -2.22151
RPN1 ribophorin I -2.18336
SOAT1 sterol O-acyltransferase 1 -2.1784
ZNF236 zinc finger protein 236 -2.17163
ADAL adenosine deaminase-like -2.16611
YLPM1 YLP motif containing 1 -2.16034
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.15906
RPL13A ribosomal protein L13a -2.14493
TMEM184C transmembrane protein 184C -2.13718
GID8 GID complex subunit 8 -2.12283
CSPP1 centrosome and spindle pole associated protein 1 -2.11666
RBM17 RNA binding motif protein 17 -2.10726
ERGIC2 ERGIC and golgi 2 -2.08359
RCN1 reticulocalbin 1, EF-hand calcium binding domain -2.08197
HIST1H2BO histone cluster 1, H2bo -2.07821
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -2.07143
C20ORF196 chromosome 20 open reading frame 196 -2.06931
FKBP1A FK506 binding protein 1A, 12kDa -2.06331
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -2.0566
FAT1 FAT atypical cadherin 1 -2.05072
WASF3 WAS protein family, member 3 -2.03969
ZNF559-ZNF177 ZNF559-ZNF177 readthrough -2.01278
COL1A1 collagen, type I, alpha 1 -2.00977
TSN translin -2.00927
CSE1L CSE1 chromosome segregation 1-like (yeast) -1.99993
TBP TATA box binding protein -1.99192
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase -1.98458
SEP15 15 kDa selenoprotein -1.97002
CLVS1 clavesin 1 -1.96136
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -1.96125
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -1.95763
MORC4 MORC family CW-type zinc finger 4 -1.95673
TM9SF2 transmembrane 9 superfamily member 2 -1.94521
DPYSL2 dihydropyrimidinase-like 2 -1.94149
MPV17 MpV17 mitochondrial inner membrane protein -1.9402
PCGF6 polycomb group ring finger 6 -1.93398
MPC1 mitochondrial pyruvate carrier 1 -1.93155
CNPY4 canopy FGF signaling regulator 4 -1.91354
GLRX3 glutaredoxin 3 -1.87418
GGPS1 geranylgeranyl diphosphate synthase 1 -1.87103
BBS1 Bardet-Biedl syndrome 1 -1.87059
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -1.85433
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -1.84744
SEC23A Sec23 homolog A (S. cerevisiae) -1.84573
C21ORF59 chromosome 21 open reading frame 59 -1.832
ERGIC3 ERGIC and golgi 3 -1.82519
H2AFV H2A histone family, member V -1.82223
C1GALT1C1 C1GALT1-specific chaperone 1 -1.81994
MRPL10 mitochondrial ribosomal protein L10 -1.81579
DEGS1 delta(4)-desaturase, sphingolipid 1 -1.80953
TRIM23 tripartite motif containing 23 -1.80859
ZNF638 zinc finger protein 638 -1.80853
RAP2C RAP2C, member of RAS oncogene family -1.80183
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -1.77494
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -1.76426
IDUA iduronidase, alpha-L- -1.75803
SMG7 SMG7 nonsense mediated mRNA decay factor -1.75743
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -1.75501
RPS3 ribosomal protein S3 -1.7542
CCDC90B coiled-coil domain containing 90B -1.74472
ZFAND1 zinc finger, AN1-type domain 1 -1.74334
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -1.74319
CCNL2 cyclin L2 -1.74044
LAMP1 lysosomal-associated membrane protein 1 -1.73783
NDFIP2 Nedd4 family interacting protein 2 -1.73563
GIGYF2 GRB10 interacting GYF protein 2 -1.73493
MTTP microsomal triglyceride transfer protein -1.71187
CXXC5 CXXC finger protein 5 -1.70834
ZFAND6 zinc finger, AN1-type domain 6 -1.70184
POLH polymerase (DNA directed), eta -1.70013
NDFIP1 Nedd4 family interacting protein 1 -1.6922
CD38 CD38 molecule -1.68984
IREB2 iron-responsive element binding protein 2 -1.68919
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -1.68732
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -1.67883
RBBP5 retinoblastoma binding protein 5 -1.67868
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -1.67445
SAR1B secretion associated, Ras related GTPase 1B -1.66811
ARL6 ADP-ribosylation factor-like 6 -1.65972
WDR92 WD repeat domain 92 -1.65934
EML4 echinoderm microtubule associated protein like 4 -1.655
HIST2H3A histone cluster 2, H3a -1.6533
VCAN versican -1.65004
KANSL1L KAT8 regulatory NSL complex subunit 1-like -1.64094
ERBB3 erb-b2 receptor tyrosine kinase 3 -1.63932
MOB4 MOB family member 4, phocein -1.63758
HMGXB3 HMG box domain containing 3 -1.63606
PAIP1 poly(A) binding protein interacting protein 1 -1.63211
TCF12 transcription factor 12 -1.62612
RHEB Ras homolog enriched in brain -1.62295
RPL3 ribosomal protein L3 -1.61977
CNPY2 canopy FGF signaling regulator 2 -1.60908
OGN osteoglycin -1.60563
MAMDC2 MAM domain containing 2 -1.60255
RAN RAN, member RAS oncogene family -1.59261
HSF2 heat shock transcription factor 2 -1.58874
APP amyloid beta (A4) precursor protein -1.58001
FGFRL1 fibroblast growth factor receptor-like 1 -1.57983
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -1.57705
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.57628
KIAA1033 KIAA1033 -1.57462
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -1.57226
RBBP7 retinoblastoma binding protein 7 -1.57158
SDHAF3 succinate dehydrogenase complex assembly factor 3 -1.57051
ULK2 unc-51 like autophagy activating kinase 2 -1.56606
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -1.56509
PCM1 pericentriolar material 1 -1.56172
VKORC1 vitamin K epoxide reductase complex, subunit 1 -1.55565
PIAS2 protein inhibitor of activated STAT, 2 -1.55475
MICALL1 MICAL-like 1 -1.55413
GOLPH3L golgi phosphoprotein 3-like -1.55103
SFPQ splicing factor proline/glutamine-rich -1.54667
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -1.54612
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -1.54114
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -1.53522
KCTD3 potassium channel tetramerization domain containing 3 -1.53505
YME1L1 YME1-like 1 ATPase -1.52349
THOC1 THO complex 1 -1.52313
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -1.51589
NTPCR nucleoside-triphosphatase, cancer-related -1.51376
WDR77 WD repeat domain 77 -1.50315
CHD2 chromodomain helicase DNA binding protein 2 -1.50274
RNF13 ring finger protein 13 -1.49716
FUBP1 far upstream element (FUSE) binding protein 1 -1.49631
ZNF148 zinc finger protein 148 -1.49494
CNBP CCHC-type zinc finger, nucleic acid binding protein -1.49204
TUBGCP4 tubulin, gamma complex associated protein 4 -1.49127
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -1.49122
RPL38 ribosomal protein L38 -1.48733
NAGK N-acetylglucosamine kinase -1.48061
SERBP1 SERPINE1 mRNA binding protein 1 -1.48023
ZC3H7A zinc finger CCCH-type containing 7A -1.47878
CCDC103 coiled-coil domain containing 103 -1.46755
SRSF1 serine/arginine-rich splicing factor 1 -1.46068
HSPB11 heat shock protein family B (small), member 11 -1.45787
STRN striatin, calmodulin binding protein -1.45662
SECTM1 secreted and transmembrane 1 -1.45353
TPST1 tyrosylprotein sulfotransferase 1 -1.45132
UBC ubiquitin C -1.45127
USP25 ubiquitin specific peptidase 25 -1.45069
CCDC66 coiled-coil domain containing 66 -1.44526
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -1.44337
FXR1 fragile X mental retardation, autosomal homolog 1 -1.44308
CDC37L1 cell division cycle 37-like 1 -1.44176
OPN1SW opsin 1 (cone pigments), short-wave-sensitive -1.4409
PTEN phosphatase and tensin homolog -1.43383
MDM4 MDM4, p53 regulator -1.42848
CCNH cyclin H -1.42786
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -1.42391
ZNF367 zinc finger protein 367 -1.42217
UBE2H ubiquitin-conjugating enzyme E2H -1.421
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -1.41993
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) -1.4164
TUSC3 tumor suppressor candidate 3 -1.41376
MKKS McKusick-Kaufman syndrome -1.40901
UBE3A ubiquitin protein ligase E3A -1.40215
HS1BP3 HCLS1 binding protein 3 -1.40101
SOX5 SRY (sex determining region Y)-box 5 -1.40002
PCOLCE procollagen C-endopeptidase enhancer -1.39998
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -1.39688
NR1H3 nuclear receptor subfamily 1, group H, member 3 -1.39269
UBN2 ubinuclein 2 -1.39247
RCN2 reticulocalbin 2, EF-hand calcium binding domain -1.39204
GGCX gamma-glutamyl carboxylase -1.39199
EMC1 ER membrane protein complex subunit 1 -1.39131
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -1.39047
GNS glucosamine (N-acetyl)-6-sulfatase -1.38785
MEOX1 mesenchyme homeobox 1 -1.3846
CNOT7 CCR4-NOT transcription complex, subunit 7 -1.38432
BRWD3 bromodomain and WD repeat domain containing 3 -1.38266
ZEB2 zinc finger E-box binding homeobox 2 -1.38102
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -1.3802
NUDCD1 NudC domain containing 1 -1.3753
COL2A1 collagen, type II, alpha 1 -1.37369
FAM109A family with sequence similarity 109, member A -1.37064
TXNRD2 thioredoxin reductase 2 -1.36857
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -1.36625
TMCC1 transmembrane and coiled-coil domain family 1 -1.36145
SCRN3 secernin 3 -1.36111
SRSF6 serine/arginine-rich splicing factor 6 -1.36091
TMEM170A transmembrane protein 170A -1.36026
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -1.35842
GMFB glia maturation factor, beta -1.35836
PCED1A PC-esterase domain containing 1A -1.35642
SAR1A secretion associated, Ras related GTPase 1A -1.35119
KCTD14 potassium channel tetramerization domain containing 14 -1.34987
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -1.34737
CXORF38 chromosome X open reading frame 38 -1.34697
TADA1 transcriptional adaptor 1 -1.34337
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -1.33971
WDR75 WD repeat domain 75 -1.33512
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.33403
MAGOHB mago-nashi homolog B (Drosophila) -1.33224
TTC14 tetratricopeptide repeat domain 14 -1.33161
MINA MYC induced nuclear antigen -1.32713
CNOT2 CCR4-NOT transcription complex, subunit 2 -1.32603
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -1.3258
DMTF1 cyclin D binding myb-like transcription factor 1 -1.32371
TMEM126A transmembrane protein 126A -1.32274
CHMP4B charged multivesicular body protein 4B -1.32145
RAB8A RAB8A, member RAS oncogene family -1.31547
XPO1 exportin 1 -1.3152
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -1.31415
RNF145 ring finger protein 145 -1.31222
LAMA2 laminin, alpha 2 -1.31169
PDPN podoplanin -1.30994
ORC4 origin recognition complex, subunit 4 -1.30993
TMEM33 transmembrane protein 33 -1.30751
KDM5A lysine (K)-specific demethylase 5A -1.30745
MCM4 minichromosome maintenance complex component 4 -1.30534
CDK6 cyclin-dependent kinase 6 -1.3047
FUCA2 fucosidase, alpha-L- 2, plasma -1.29826
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 -1.2896
MINPP1 multiple inositol-polyphosphate phosphatase 1 -1.28912
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -1.2867
ACTG1 actin gamma 1 -1.28599
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -1.2855
UBE2B ubiquitin-conjugating enzyme E2B -1.28201
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -1.2806
CCNI cyclin I -1.27491
RXFP2 relaxin/insulin-like family peptide receptor 2 -1.27151
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 -1.27017
TMEM209 transmembrane protein 209 -1.26985
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 -1.26836
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -1.26811
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -1.26756
LRRC4B leucine rich repeat containing 4B -1.26511
MANEA mannosidase, endo-alpha -1.26341
FAM47A family with sequence similarity 47, member A -1.26334
PRPF31 pre-mRNA processing factor 31 -1.26328
IFT80 intraflagellar transport 80 -1.25817
LMAN2L lectin, mannose-binding 2-like -1.25785
SS18 synovial sarcoma translocation, chromosome 18 -1.2572
ACBD5 acyl-CoA binding domain containing 5 -1.257
SRP19 signal recognition particle 19kDa -1.25674
APOD apolipoprotein D -1.2565
CMC4 C-x(9)-C motif containing 4 -1.25558
CPD carboxypeptidase D -1.25533
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -1.25436
LYRM2 LYR motif containing 2 -1.2535
RPLP0 ribosomal protein, large, P0 -1.25196
C2ORF54 chromosome 2 open reading frame 54 -1.24966
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -1.24906
TMEM183A transmembrane protein 183A -1.24831
CP ceruloplasmin (ferroxidase) -1.24699
RNF11 ring finger protein 11 -1.24503
STX7 syntaxin 7 -1.24359
CRLF3 cytokine receptor-like factor 3 -1.24252
CUL4A cullin 4A -1.2419
IDS iduronate 2-sulfatase -1.24167
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -1.2385
ANKFY1 ankyrin repeat and FYVE domain containing 1 -1.23791
LRRK1 leucine-rich repeat kinase 1 -1.23774
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) -1.23751
TMEM60 transmembrane protein 60 -1.23501
KDM4A lysine (K)-specific demethylase 4A -1.23456
C20ORF194 chromosome 20 open reading frame 194 -1.23374