Diabetic Neuropathies Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

59 genes associated with the Diabetic Neuropathies phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA2B adrenoceptor alpha 2B
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
C10ORF2 chromosome 10 open reading frame 2
CAPN10 calpain 10
CAT catalase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DRD3 dopamine receptor D3
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HP haptoglobin
IFNG interferon, gamma
IL10 interleukin 10
IL4 interleukin 4
LPL lipoprotein lipase
MIOX myo-inositol oxygenase
MT-TL1 tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NCALD neurocalcin delta
NOS1 nitric oxide synthase 1 (neuronal)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
OPRM1 opioid receptor, mu 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARP1 poly (ADP-ribose) polymerase 1
POLG polymerase (DNA directed), gamma
PPARG peroxisome proliferator-activated receptor gamma
SELE selectin E
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SUMO4 small ubiquitin-like modifier 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A