Diabetic Nephropathies Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D003928
Similar Terms
Downloads & Tools

Genes

626 genes/proteins associated with the disease Diabetic Nephropathies from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.88009
DGKH diacylglycerol kinase, eta 2.88009
ALB albumin 2.88009
NFE2L2 nuclear factor, erythroid 2-like 2 2.88009
COL4A1 collagen, type IV, alpha 1 2.88009
AOC3 amine oxidase, copper containing 3 2.88009
MIR145 microRNA 145 2.88009
PRKCE protein kinase C, epsilon 2.88009
TINAG tubulointerstitial nephritis antigen 2.88009
VDAC1 voltage-dependent anion channel 1 2.88009
VDAC2 voltage-dependent anion channel 2 2.88009
TXNIP thioredoxin interacting protein 2.88009
NOS3 nitric oxide synthase 3 (endothelial cell) 2.88009
GAS6 growth arrest-specific 6 2.88009
MDK midkine (neurite growth-promoting factor 2) 2.88009
AXL AXL receptor tyrosine kinase 2.88009
ACE angiotensin I converting enzyme 2.88009
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 2.88009
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.88009
KDR kinase insert domain receptor 2.88009
KLK1 kallikrein 1 2.88009
INS insulin 2.88009
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.88009
ACE2 angiotensin I converting enzyme 2 2.88009
TGFB1 transforming growth factor, beta 1 2.88009
TGFBI transforming growth factor, beta-induced, 68kDa 2.88009
CCL2 chemokine (C-C motif) ligand 2 2.88009
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.88009
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.88009
VEGFA vascular endothelial growth factor A 2.88009
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.88009
ADIPOQ adiponectin, C1Q and collagen domain containing 2.88009
ELMO1 engulfment and cell motility 1 2.88009
NOS2 nitric oxide synthase 2, inducible 2.45081
BCL2 B-cell CLL/lymphoma 2 2.40678
TNF tumor necrosis factor 2.40275
IL6 interleukin 6 2.39335
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.35108
IL1B interleukin 1, beta 2.34592
ICAM1 intercellular adhesion molecule 1 2.33974
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.33404
BAX BCL2-associated X protein 2.33243
CYBA cytochrome b-245, alpha polypeptide 2.31187
CAT catalase 2.29602
MAPK1 mitogen-activated protein kinase 1 2.28474
SOD1 superoxide dismutase 1, soluble 2.27688
MAPK3 mitogen-activated protein kinase 3 2.26845
ACTA2 actin, alpha 2, smooth muscle, aorta 2.25676
MMP2 matrix metallopeptidase 2 2.25592
HMOX1 heme oxygenase 1 2.24937
EDN1 endothelin 1 2.24781
VCAM1 vascular cell adhesion molecule 1 2.21267
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.19894
IFNG interferon, gamma 2.17108
BCL2L1 BCL2-like 1 2.14773
COL3A1 collagen, type III, alpha 1 2.13524
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.1317
FN1 fibronectin 1 2.11933
FOS FBJ murine osteosarcoma viral oncogene homolog 2.11447
MMP9 matrix metallopeptidase 9 2.10508
PPARG peroxisome proliferator-activated receptor gamma 2.09309
SOD2 superoxide dismutase 2, mitochondrial 2.08787
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.07961
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.04643
IGF1 insulin-like growth factor 1 (somatomedin C) 2.04554
NPPB natriuretic peptide B 2.04411
CYCS cytochrome c, somatic 2.03342
TIMP1 TIMP metallopeptidase inhibitor 1 2.02998
FASLG Fas ligand (TNF superfamily, member 6) 2.02905
NCF1 neutrophil cytosolic factor 1 2.01567
GSR glutathione reductase 2.00787
MAPK8 mitogen-activated protein kinase 8 2.0055
CTGF connective tissue growth factor 1.9915
BAD BCL2-associated agonist of cell death 1.9831
IRS1 insulin receptor substrate 1 1.9761
NPPA natriuretic peptide A 1.97508
REN renin 1.96551
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.96521
FAS Fas cell surface death receptor 1.96506
AGTR1 angiotensin II receptor, type 1 1.95721
MPO myeloperoxidase 1.94532
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.94311
COL1A1 collagen, type I, alpha 1 1.94264
PPARA peroxisome proliferator-activated receptor alpha 1.93322
CD36 CD36 molecule (thrombospondin receptor) 1.92642
SPP1 secreted phosphoprotein 1 1.92091
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.9196
INSR insulin receptor 1.90952
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.8978
SIRT1 sirtuin 1 1.88979
CXCL8 chemokine (C-X-C motif) ligand 8 1.88109
DDIT3 DNA-damage-inducible transcript 3 1.87892
PDGFB platelet-derived growth factor beta polypeptide 1.87126
TP53 tumor protein p53 1.86958
GSK3B glycogen synthase kinase 3 beta 1.8689
LEP leptin 1.8655
MAPK9 mitogen-activated protein kinase 9 1.86515
JUN jun proto-oncogene 1.86358
NQO1 NAD(P)H dehydrogenase, quinone 1 1.85256
CYBB cytochrome b-245, beta polypeptide 1.85186
PARP1 poly (ADP-ribose) polymerase 1 1.84605
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.83325
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.82779
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.82621
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.82551
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.81921
CCND1 cyclin D1 1.80172
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.79751
IL10 interleukin 10 1.79369
SMAD3 SMAD family member 3 1.78091
MAPK14 mitogen-activated protein kinase 14 1.77374
NOX4 NADPH oxidase 4 1.76501
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.75361
GPX1 glutathione peroxidase 1 1.75221
CCL5 chemokine (C-C motif) ligand 5 1.74842
HSPB1 heat shock 27kDa protein 1 1.7426
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.73129
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.73069
BID BH3 interacting domain death agonist 1.72717
EDNRA endothelin receptor type A 1.72219
NCF2 neutrophil cytosolic factor 2 1.72137
EGR1 early growth response 1 1.72014
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.71912
IL2 interleukin 2 1.71009
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.70947
AGTR2 angiotensin II receptor, type 2 1.70388
BBC3 BCL2 binding component 3 1.6947
COL1A2 collagen, type I, alpha 2 1.6947
SREBF1 sterol regulatory element binding transcription factor 1 1.6906
PRKCD protein kinase C, delta 1.6891
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.68612
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.68358
AGER advanced glycosylation end product-specific receptor 1.67868
NOS1 nitric oxide synthase 1 (neuronal) 1.67483
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.66684
APP amyloid beta (A4) precursor protein 1.66038
PCNA proliferating cell nuclear antigen 1.6593
PECAM1 platelet/endothelial cell adhesion molecule 1 1.65489
PRKCA protein kinase C, alpha 1.65424
CCNE1 cyclin E1 1.65402
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.65292
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.64775
IL12A interleukin 12A 1.63966
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.63428
SP1 Sp1 transcription factor 1.63384
GADD45A growth arrest and DNA-damage-inducible, alpha 1.63072
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.62938
CDK2 cyclin-dependent kinase 2 1.62893
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.62803
G6PD glucose-6-phosphate dehydrogenase 1.6278
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.62713
CAV1 caveolin 1, caveolae protein, 22kDa 1.62601
APOE apolipoprotein E 1.62468
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.62379
CD44 CD44 molecule (Indian blood group) 1.62222
STAT1 signal transducer and activator of transcription 1, 91kDa 1.62153
TIMP2 TIMP metallopeptidase inhibitor 2 1.61828
RUNX2 runt-related transcription factor 2 1.61598
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.60874
EPO erythropoietin 1.60641
THBS1 thrombospondin 1 1.60407
CREB1 cAMP responsive element binding protein 1 1.60221
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.59966
GFAP glial fibrillary acidic protein 1.59778
CHUK conserved helix-loop-helix ubiquitous kinase 1.59731
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.59451
FOXO1 forkhead box O1 1.58818
NRF1 nuclear respiratory factor 1 1.57994
GCLC glutamate-cysteine ligase, catalytic subunit 1.57994
CCND3 cyclin D3 1.57971
NAMPT nicotinamide phosphoribosyltransferase 1.57735
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.57618
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.56582
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.5619
BIRC5 baculoviral IAP repeat containing 5 1.5619
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.55427
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.54815
IL18 interleukin 18 1.54232
PLAT plasminogen activator, tissue 1.54232
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.5382
TLR4 toll-like receptor 4 1.53748
CPT1A carnitine palmitoyltransferase 1A (liver) 1.53627
GJA1 gap junction protein, alpha 1, 43kDa 1.53431
CCNB1 cyclin B1 1.5311
XDH xanthine dehydrogenase 1.5311
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.53086
FGF2 fibroblast growth factor 2 (basic) 1.52938
IGF1R insulin-like growth factor 1 receptor 1.52865
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.52667
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.51708
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.51657
LIPE lipase, hormone-sensitive 1.51155
ACHE acetylcholinesterase (Yt blood group) 1.5065
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.49686
LPL lipoprotein lipase 1.49686
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.49558
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.49432
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.49174
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.49148
TXN thioredoxin 1.49148
LHB luteinizing hormone beta polypeptide 1.48941
AHR aryl hydrocarbon receptor 1.48941
ADRB2 adrenoceptor beta 2, surface 1.48941
G0S2 G0/G1 switch 2 1.48505
LDLR low density lipoprotein receptor 1.48068
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.47426
CCNA2 cyclin A2 1.47219
GSTA2 glutathione S-transferase alpha 2 1.46935
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.46781
MMP1 matrix metallopeptidase 1 1.45857
MMP13 matrix metallopeptidase 13 1.45723
IL12B interleukin 12B 1.45405
ALAD aminolevulinate dehydratase 1.44763
SOD3 superoxide dismutase 3, extracellular 1.44763
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.44084
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.44001
VIM vimentin 1.43864
TJP1 tight junction protein 1 1.43727
RB1 retinoblastoma 1 1.43673
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.43347
CPT1B carnitine palmitoyltransferase 1B (muscle) 1.43184
FABP4 fatty acid binding protein 4, adipocyte 1.42913
RPA3 replication protein A3, 14kDa 1.41911
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.41775
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.41775
CXCL12 chemokine (C-X-C motif) ligand 12 1.41775
CP ceruloplasmin (ferroxidase) 1.41396
S100B S100 calcium binding protein B 1.41285
PLAU plasminogen activator, urokinase 1.40815
CDK4 cyclin-dependent kinase 4 1.40732
TH tyrosine hydroxylase 1.40595
FASN fatty acid synthase 1.40595
HSPA1A heat shock 70kDa protein 1A 1.40457
CKS1B CDC28 protein kinase regulatory subunit 1B 1.40064
KNG1 kininogen 1 1.39897
TEK TEK tyrosine kinase, endothelial 1.39646
TERT telomerase reverse transcriptase 1.39451
APOB apolipoprotein B 1.39451
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.39366
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.39254
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.3917
UNG uracil-DNA glycosylase 1.3917
KEAP1 kelch-like ECH-associated protein 1 1.39002
BIRC2 baculoviral IAP repeat containing 2 1.39002
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 1.38584
CFLAR CASP8 and FADD-like apoptosis regulator 1.38555
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.38527
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.38441
SMAD2 SMAD family member 2 1.38015
HDAC1 histone deacetylase 1 1.38015
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.37246
TXNRD1 thioredoxin reductase 1 1.36933
CRP C-reactive protein, pentraxin-related 1.36905
FSHB follicle stimulating hormone, beta polypeptide 1.36905
TGFB2 transforming growth factor, beta 2 1.3682
MAP2K1 mitogen-activated protein kinase kinase 1 1.36735
ESR1 estrogen receptor 1 1.36619
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.36562
MKI67 marker of proliferation Ki-67 1.36562
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.36533
NDRG1 N-myc downstream regulated 1 1.36161
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.35962
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.35962
SGK1 serum/glucocorticoid regulated kinase 1 1.3556
H2AFX H2A histone family, member X 1.35213
IL5 interleukin 5 1.35213
EGFR epidermal growth factor receptor 1.35184
F3 coagulation factor III (thromboplastin, tissue factor) 1.35127
IL4 interleukin 4 1.34983
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.34983
CCND2 cyclin D2 1.34926
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.34869
BGLAP bone gamma-carboxyglutamate (gla) protein 1.34723
EIF5 eukaryotic translation initiation factor 5 1.34343
IGFBP1 insulin-like growth factor binding protein 1 1.34314
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.34314
GSTM3 glutathione S-transferase mu 3 (brain) 1.34111
CLU clusterin 1.34082
PDX1 pancreatic and duodenal homeobox 1 1.33966
OAT ornithine aminotransferase 1.33938
TFRC transferrin receptor 1.33434
FOXO3 forkhead box O3 1.33434
CDK1 cyclin-dependent kinase 1 1.33257
MCL1 myeloid cell leukemia 1 1.33257
TFAM transcription factor A, mitochondrial 1.32637
G6PC glucose-6-phosphatase, catalytic subunit 1.32428
CYP3A cytochrome P450, family 3, subfamily A 1.3228
CREBBP CREB binding protein 1.32162
BDKRB2 bradykinin receptor B2 1.31956
MMP7 matrix metallopeptidase 7 1.31956
PPARD peroxisome proliferator-activated receptor delta 1.31927
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.31927
STAR steroidogenic acute regulatory protein 1.31867
ADRB3 adrenoceptor beta 3 1.31626
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.31566
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.31446
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.31446
IGFBP4 insulin-like growth factor binding protein 4 1.31297
PTHLH parathyroid hormone-like hormone 1.31297
IL1A interleukin 1, alpha 1.31267
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.31178
CALR calreticulin 1.30941
CD86 CD86 molecule 1.30819
CXCL2 chemokine (C-X-C motif) ligand 2 1.30788
ANGPT2 angiopoietin 2 1.30635
LDHB lactate dehydrogenase B 1.30329
GLUL glutamate-ammonia ligase 1.30238
F2 coagulation factor II (thrombin) 1.30056
TGFBR1 transforming growth factor, beta receptor 1 1.30026
PRKCB protein kinase C, beta 1.29996
PKM pyruvate kinase, muscle 1.29996
CXCL10 chemokine (C-X-C motif) ligand 10 1.29875
VASN vasorin 1.29688
APAF1 apoptotic peptidase activating factor 1 1.29502
ERN1 endoplasmic reticulum to nucleus signaling 1 1.29379
ALOX5 arachidonate 5-lipoxygenase 1.29133
MT1A metallothionein 1A 1.29133
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.29072
ADRB1 adrenoceptor beta 1 1.29041
DCN decorin 1.28765
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.28579
JAK2 Janus kinase 2 1.28579
PTGES prostaglandin E synthase 1.28456
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.28456
TBXA2R thromboxane A2 receptor 1.28425
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.28395
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.28364
ACACA acetyl-CoA carboxylase alpha 1.28364
BIRC3 baculoviral IAP repeat containing 3 1.28241
FOXA2 forkhead box A2 1.27997
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.27905
IER3 immediate early response 3 1.27471
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.27347
GCLM glutamate-cysteine ligase, modifier subunit 1.27224
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.26947
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.26452
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.26144
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.26113
HNF4A hepatocyte nuclear factor 4, alpha 1.26113
ATF3 activating transcription factor 3 1.26113
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.25838
ELOVL6 ELOVL fatty acid elongase 6 1.25838
PNPLA2 patatin-like phospholipase domain containing 2 1.25557
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.25307
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.25307
HSPA4 heat shock 70kDa protein 4 1.25276
KLHL24 kelch-like family member 24 1.24812
APOA1 apolipoprotein A-I 1.24812
GSTM1 glutathione S-transferase mu 1 1.24591
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.24496
LGALS1 lectin, galactoside-binding, soluble, 1 1.24465
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.2415
CXCR4 chemokine (C-X-C motif) receptor 4 1.24087
FGF21 fibroblast growth factor 21 1.24056
EGLN3 egl-9 family hypoxia-inducible factor 3 1.24056
GGT1 gamma-glutamyltransferase 1 1.2393
ENO1 enolase 1, (alpha) 1.23868
E2F1 E2F transcription factor 1 1.2368
ERBB2 erb-b2 receptor tyrosine kinase 2 1.2368
HSPE1 heat shock 10kDa protein 1 1.2368
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.23296
CTSB cathepsin B 1.23265
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.23074
HRAS Harvey rat sarcoma viral oncogene homolog 1.23042
PTX3 pentraxin 3, long 1.22948
F2R coagulation factor II (thrombin) receptor 1.22884
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.22884
HMGB1 high mobility group box 1 1.22884
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.22884
ATF4 activating transcription factor 4 1.22853
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.2279
AQP1 aquaporin 1 (Colton blood group) 1.22632
FLT1 fms-related tyrosine kinase 1 1.22632
MCM7 minichromosome maintenance complex component 7 1.22599
NFE2L1 nuclear factor, erythroid 2-like 1 1.22501
ATM ATM serine/threonine kinase 1.22469
C3 complement component 3 1.22274
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.2208
SFPQ splicing factor proline/glutamine-rich 1.21887
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.21791
ODC1 ornithine decarboxylase 1 1.21631
BMP7 bone morphogenetic protein 7 1.21534
COL18A1 collagen, type XVIII, alpha 1 1.21534
LTA lymphotoxin alpha 1.21534
ENG endoglin 1.21468
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.21337
MMP3 matrix metallopeptidase 3 1.21304
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.20526
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.20526
ELK1 ELK1, member of ETS oncogene family 1.20493
UQCRC1 ubiquinol-cytochrome c reductase core protein I 1.20427
CTF1 cardiotrophin 1 1.20427
THBS2 thrombospondin 2 1.20427
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 1.20427
DES desmin 1.20163
FBP1 fructose-1,6-bisphosphatase 1 1.20163
SMAD7 SMAD family member 7 1.19835
CDK6 cyclin-dependent kinase 6 1.19835
RPS6 ribosomal protein S6 1.19835
AR androgen receptor 1.19704
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 1.19477
ERO1L ERO1-like (S. cerevisiae) 1.19445
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.19146
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.19146
SPHK1 sphingosine kinase 1 1.19146
APLN apelin 1.18948
GSTA4 glutathione S-transferase alpha 4 1.18849
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.18816
MME membrane metallo-endopeptidase 1.18816
C1S complement component 1, s subcomponent 1.18816
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.18652
CD40 CD40 molecule, TNF receptor superfamily member 5 1.18652
RGS2 regulator of G-protein signaling 2 1.18652
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.18652
CD68 CD68 molecule 1.18521
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.18521
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.18489
GSTP1 glutathione S-transferase pi 1 1.18489
TIMP3 TIMP metallopeptidase inhibitor 3 1.18193
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.18026
BGN biglycan 1.18026
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.17959
CCL3 chemokine (C-C motif) ligand 3 1.17893
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.17893
IGFBP3 insulin-like growth factor binding protein 3 1.17761
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 1.17563
EPOR erythropoietin receptor 1.17563
RARA retinoic acid receptor, alpha 1.17497
PTK2 protein tyrosine kinase 2 1.17497
ARNT aryl hydrocarbon receptor nuclear translocator 1.17268
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.17268
TMSB4X thymosin beta 4, X-linked 1.17101
PKLR pyruvate kinase, liver and RBC 1.16967
WAS Wiskott-Aldrich syndrome 1.16967
TGFA transforming growth factor, alpha 1.16833
CSF1 colony stimulating factor 1 (macrophage) 1.16633
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.16633
GUSB glucuronidase, beta 1.16633
TLR2 toll-like receptor 2 1.16368
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.16335
PSAT1 phosphoserine aminotransferase 1 1.16335
GLO1 glyoxalase I 1.16236
GH1 growth hormone 1 1.15933
GRB10 growth factor receptor-bound protein 10 1.15797
CAPG capping protein (actin filament), gelsolin-like 1.15797
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.15763
ACO2 aconitase 2, mitochondrial 1.15458
IGF2 insulin-like growth factor 2 1.1529
IRAK1 interleukin-1 receptor-associated kinase 1 1.14954
PEMT phosphatidylethanolamine N-methyltransferase 1.14885
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.14885
PGF placental growth factor 1.14507
GPX3 glutathione peroxidase 3 1.142
INSIG1 insulin induced gene 1 1.142
BRCA1 breast cancer 1, early onset 1.13997
BAK1 BCL2-antagonist/killer 1 1.13793
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.13518
CD80 CD80 molecule 1.13449
ALPL alkaline phosphatase, liver/bone/kidney 1.13381
SOCS3 suppressor of cytokine signaling 3 1.13381
POSTN periostin, osteoblast specific factor 1.13313
ADORA2A adenosine A2a receptor 1.13177
BECN1 beclin 1, autophagy related 1.13177
SELE selectin E 1.13177
GSN gelsolin 1.13177
LIF leukemia inhibitory factor 1.13177
DUSP10 dual specificity phosphatase 10 1.12906
ATF2 activating transcription factor 2 1.12634
CDC6 cell division cycle 6 1.12634
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.1253
MGP matrix Gla protein 1.12357
XBP1 X-box binding protein 1 1.12151
MXD1 MAX dimerization protein 1 1.12117
MAP2K3 mitogen-activated protein kinase kinase 3 1.12117
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.12117
B2M beta-2-microglobulin 1.12082
PLAUR plasminogen activator, urokinase receptor 1.11945
HSPA1L heat shock 70kDa protein 1-like 1.11775
PML promyelocytic leukemia 1.11741
LCN2 lipocalin 2 1.11571
EIF5A eukaryotic translation initiation factor 5A 1.11396
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.1136
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.1136
LYN LYN proto-oncogene, Src family tyrosine kinase 1.1136
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.1129
MRPL12 mitochondrial ribosomal protein L12 1.11116
ZFP36 ZFP36 ring finger protein 1.11046
CCL11 chemokine (C-C motif) ligand 11 1.11046
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.11046
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.11011
ACTB actin, beta 1.10977
TYR tyrosinase 1.10769
ADIPOR2 adiponectin receptor 2 1.10631
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.10562
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.10424
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.10246
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 1.10033
TAGLN transgelin 1.09998
DDIT4 DNA-damage-inducible transcript 4 1.09998
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.09998
ANGPTL2 angiopoietin-like 2 1.09963
NDRG4 NDRG family member 4 1.09963
VCAN versican 1.09892
WNT5A wingless-type MMTV integration site family, member 5A 1.09892
ITGAV integrin, alpha V 1.09892
AQP3 aquaporin 3 (Gill blood group) 1.09751
CASP12 caspase 12 (gene/pseudogene) 1.09751
CTSD cathepsin D 1.09436
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.09436
BMP2 bone morphogenetic protein 2 1.09262
BMP4 bone morphogenetic protein 4 1.09262
FOSL1 FOS-like antigen 1 1.09262
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.09262
POU5F1 POU class 5 homeobox 1 1.0919
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 1.08904
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.08868
ACOT7 acyl-CoA thioesterase 7 1.08868
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.08833
POR P450 (cytochrome) oxidoreductase 1.08762
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.08513
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.08513
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.08513
DAXX death-domain associated protein 1.0784
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 1.07804
GATA4 GATA binding protein 4 1.07804
PON2 paraoxonase 2 1.07804
CFD complement factor D (adipsin) 1.07804
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.07768
JUND jun D proto-oncogene 1.07553
RGS4 regulator of G-protein signaling 4 1.07482
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.07482
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.07411
ADCY7 adenylate cyclase 7 1.07305
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.07269
HPCAL1 hippocalcin-like 1 1.07269
LITAF lipopolysaccharide-induced TNF factor 1.07128
VWF von Willebrand factor 1.07128
HBEGF heparin-binding EGF-like growth factor 1.07093
MAPK11 mitogen-activated protein kinase 11 1.06771
PRL prolactin 1.06771
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.06588
STIP1 stress-induced phosphoprotein 1 1.06479
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 1.06297
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.06261
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.06152
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.06152
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.06152
RAD50 RAD50 homolog (S. cerevisiae) 1.05828
EMP1 epithelial membrane protein 1 1.05828
FADS1 fatty acid desaturase 1 1.05828
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.05828
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.05828
MEF2A myocyte enhancer factor 2A 1.05793
RAD51 RAD51 recombinase 1.05685
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.05648
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.05498
DLG1 discs, large homolog 1 (Drosophila) 1.05312
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.05274
IFI27 interferon, alpha-inducible protein 27 1.05274
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.05274
GPX2 glutathione peroxidase 2 1.05237
CDC20 cell division cycle 20 1.052
CAPN2 calpain 2, (m/II) large subunit 1.052
CBS cystathionine-beta-synthase 1.04868
ADM adrenomedullin 1.04757
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.04757
MIR146A microRNA 146a 1.04574
DUSP5 dual specificity phosphatase 5 1.04574
EP300 E1A binding protein p300 1.04574
GPNMB glycoprotein (transmembrane) nmb 1.04538
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 1.04501
STAT5B signal transducer and activator of transcription 5B 1.04314
DAP death-associated protein 1.04314
PC pyruvate carboxylase 1.03864
FTH1 ferritin, heavy polypeptide 1 1.03864
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.03864
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.03641
NFIL3 nuclear factor, interleukin 3 regulated 1.03641
BDNF brain-derived neurotrophic factor 1.03456
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.03419
LXN latexin 1.03382
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 1.03382
KLF10 Kruppel-like factor 10 1.03308
GRN granulin 1.03308
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.03308
ESR2 estrogen receptor 2 (ER beta) 1.03046
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.03009
CDC42 cell division cycle 42 1.03009
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.03009
HPSE heparanase 1.03009
CNN1 calponin 1, basic, smooth muscle 1.02933
RANBP2 RAN binding protein 2 1.02933
NME6 NME/NM23 nucleoside diphosphate kinase 6 1.02933
WSB1 WD repeat and SOCS box containing 1 1.02896
JUNB jun B proto-oncogene 1.02783
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.02708
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.02559
HDAC2 histone deacetylase 2 1.02485
AXIN2 axin 2 1.02485
ANG angiogenin, ribonuclease, RNase A family, 5 1.02485
ERCC5 excision repair cross-complementation group 5 1.02485
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.02447
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.02373
MGST1 microsomal glutathione S-transferase 1 1.02373
PON1 paraoxonase 1 1.02299
TOP2A topoisomerase (DNA) II alpha 170kDa 1.02299
PLD1 phospholipase D1, phosphatidylcholine-specific 1.02151
VCP valosin containing protein 1.02077
BCL2L2 BCL2-like 2 1.02077
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.01852
EDNRB endothelin receptor type B 1.01739
IL1RN interleukin 1 receptor antagonist 1.01739
CHEK2 checkpoint kinase 2 1.01739
RYR2 ryanodine receptor 2 (cardiac) 1.01625
ALPI alkaline phosphatase, intestinal 1.01625
LYZ lysozyme 1.01625
FADD Fas (TNFRSF6)-associated via death domain 1.01549
AMHR2 anti-Mullerian hormone receptor, type II 1.01399
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.01324
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.01286
PHB prohibitin 1.01286
VLDLR very low density lipoprotein receptor 1.01286
CTSH cathepsin H 1.01174
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.01174
ESRRA estrogen-related receptor alpha 1.01174
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.01099